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The map label for this gene is ubiA [H]

Identifier: 83721151

GI number: 83721151

Start: 1437691

End: 1438623

Strand: Direct

Name: ubiA [H]

Synonym: BTH_I1286

Alternate gene names: 83721151

Gene position: 1437691-1438623 (Clockwise)

Preceding gene: 83718988

Following gene: 83719852

Centisome position: 37.74

GC content: 65.17

Gene sequence:

>933_bases
TTGCCGCAAATCCCGTGCGGTTCTACAATGCCGGGGTTACGTTTCCGGGCCCGCCGCCCGTTCTCGCCGATGCTCGCCCG
TTTTCCCCTCTATTTGCGGCTGATCCGGATGGACAAGCCGATCGGCAGCCTGCTGCTGCTGTGGCCGACGCTCAATGCGC
TGTGGATCGCGTCCGACGGACATCCTGCGCCGTCGCTCGTCGTCATCTTCGTGCTCGGCACGCTGCTGATGCGCTCGGCC
GGCTGCGCGATCAACGATTACGCCGATCGCGATTTCGATCGCCACGTGAAGCGCACAGCCGAGCGGCCGCTCACGTCGGG
CAAGATTCGAGCATGGGAGGCGGTCGCGATCGCGGTCGGCCTTGCGCTCGTGTCGTTTCTGCTGATCCTGCCGCTCAATG
CGTTGACGAAGGAACTGTCCGTCGTCGCGGTGTTCGTCGCGGCCACCTATCCGTTCATGAAGCGTTTCTTCGCGATTCCG
CAGGCGTATCTCGGCATCGCGTTCGGCTTCGGGATTCCGATGGCGTTCGCGGCCGTGCAGGACACGGTGCCGGCGCTCGC
ATGGATGCTGCTGGCCGCCAACGTGTTCTGGTCGGTCGCGTACGACACCGCGTACGCGATGGTCGATCGCGACGACGACC
TGAAGATCGGCATGCGCACGTCGGCGATCACGTTCGGCCGCTACGACGTGCTCGCGATCATGCTCTGCTACGCGGCGATG
CTCGGCATCTACGTGTGGGTGGGCGTGACGCAGCATTTCGGCTGGCCTTACTGGGCGGGCTGGGCGGCGGCTGCCGGCTG
CTCGATCTACCATTACACGCTGATCAAGGACCGCGAGCGGATGGCGTGCTTCGCCGCGTTCCGGCACAACAACTGGCTCG
GCGGCGCGCTTTTTGCGGGGATCGCCGCGCATTACGCGCTGAGTGCGCTGTAG

Upstream 100 bases:

>100_bases
CGCGGGCGGCCTGCGCGATTCGAGCGAAGCGGTCGGGCGGGGCGCACGTGCGAACGCTGGCGGAATCGACAAAAAAGGGC
AATAGCGCCGCTCCGCGTTT

Downstream 100 bases:

>100_bases
GCGCCGCGGCGGCGGCTTTGTCCGTTCGCGCGGCAGAGAACGGAAAGCGGCCGTCAGGCCGCTTTCTCTTTTTGTGCGCC
GACGCCGTGCGCGGGCCCCG

Product: 4-hydroxybenzoate octaprenyltransferase

Products: @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MPQIPCGSTMPGLRFRARRPFSPMLARFPLYLRLIRMDKPIGSLLLLWPTLNALWIASDGHPAPSLVVIFVLGTLLMRSA
GCAINDYADRDFDRHVKRTAERPLTSGKIRAWEAVAIAVGLALVSFLLILPLNALTKELSVVAVFVAATYPFMKRFFAIP
QAYLGIAFGFGIPMAFAAVQDTVPALAWMLLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRYDVLAIMLCYAAM
LGIYVWVGVTQHFGWPYWAGWAAAAGCSIYHYTLIKDRERMACFAAFRHNNWLGGALFAGIAAHYALSAL

Sequences:

>Translated_310_residues
MPQIPCGSTMPGLRFRARRPFSPMLARFPLYLRLIRMDKPIGSLLLLWPTLNALWIASDGHPAPSLVVIFVLGTLLMRSA
GCAINDYADRDFDRHVKRTAERPLTSGKIRAWEAVAIAVGLALVSFLLILPLNALTKELSVVAVFVAATYPFMKRFFAIP
QAYLGIAFGFGIPMAFAAVQDTVPALAWMLLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRYDVLAIMLCYAAM
LGIYVWVGVTQHFGWPYWAGWAAAAGCSIYHYTLIKDRERMACFAAFRHNNWLGGALFAGIAAHYALSAL
>Mature_309_residues
PQIPCGSTMPGLRFRARRPFSPMLARFPLYLRLIRMDKPIGSLLLLWPTLNALWIASDGHPAPSLVVIFVLGTLLMRSAG
CAINDYADRDFDRHVKRTAERPLTSGKIRAWEAVAIAVGLALVSFLLILPLNALTKELSVVAVFVAATYPFMKRFFAIPQ
AYLGIAFGFGIPMAFAAVQDTVPALAWMLLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRYDVLAIMLCYAAML
GIYVWVGVTQHFGWPYWAGWAAAAGCSIYHYTLIKDRERMACFAAFRHNNWLGGALFAGIAAHYALSAL

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=289, Percent_Identity=34.2560553633218, Blast_Score=152, Evalue=4e-37,
Organism=Escherichia coli, GI1790473, Length=273, Percent_Identity=53.1135531135531, Blast_Score=280, Evalue=6e-77,
Organism=Caenorhabditis elegans, GI17553718, Length=284, Percent_Identity=32.7464788732394, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32565247, Length=280, Percent_Identity=31.4285714285714, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17553720, Length=337, Percent_Identity=28.486646884273, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI32565245, Length=137, Percent_Identity=40.1459854014599, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI32565243, Length=133, Percent_Identity=39.8496240601504, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324370, Length=215, Percent_Identity=31.6279069767442, Blast_Score=109, Evalue=4e-25,
Organism=Drosophila melanogaster, GI21355567, Length=289, Percent_Identity=32.1799307958478, Blast_Score=146, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 34286; Mature: 34155

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQIPCGSTMPGLRFRARRPFSPMLARFPLYLRLIRMDKPIGSLLLLWPTLNALWIASDG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHEEHCCCCCEEEEECCC
HPAPSLVVIFVLGTLLMRSAGCAINDYADRDFDRHVKRTAERPLTSGKIRAWEAVAIAVG
CCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LALVSFLLILPLNALTKELSVVAVFVAATYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTVPALAWMLLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRYDVLAIMLCYAAM
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEEEEEECCHHHHHHHHHHHHHH
LGIYVWVGVTQHFGWPYWAGWAAAAGCSIYHYTLIKDRERMACFAAFRHNNWLGGALFAG
HHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEHHCHHHHHHHHHHHCCCCCHHHHHHH
IAAHYALSAL
HHHHHHHHCC
>Mature Secondary Structure 
PQIPCGSTMPGLRFRARRPFSPMLARFPLYLRLIRMDKPIGSLLLLWPTLNALWIASDG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHEEHCCCCCEEEEECCC
HPAPSLVVIFVLGTLLMRSAGCAINDYADRDFDRHVKRTAERPLTSGKIRAWEAVAIAVG
CCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LALVSFLLILPLNALTKELSVVAVFVAATYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTVPALAWMLLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRYDVLAIMLCYAAM
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEEEEEECCHHHHHHHHHHHHHH
LGIYVWVGVTQHFGWPYWAGWAAAAGCSIYHYTLIKDRERMACFAAFRHNNWLGGALFAG
HHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEHHCHHHHHHHHHHHCCCCCHHHHHHH
IAAHYALSAL
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-Hydroxybenzoate; Farnesylfarnesylgeraniol [C]

Specific reaction: 4-Hydroxybenzoate + Farnesylfarnesylgeraniol = @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA