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The map label for this gene is hmp [H]

Identifier: 83720496

GI number: 83720496

Start: 1446773

End: 1447981

Strand: Direct

Name: hmp [H]

Synonym: BTH_I1294

Alternate gene names: 83720496

Gene position: 1446773-1447981 (Clockwise)

Preceding gene: 83719852

Following gene: 83719747

Centisome position: 37.98

GC content: 66.83

Gene sequence:

>1209_bases
ATGACGCAGATGACCGCCGAGCAAATGGCCCGAGTGAAAGCGACCGCCCCGGTTCTCGCGGAGCACGGCGCGACGATCAC
GAAGCATTTTTATCAGCGGATGTTCGGACGCCACCCCGAACTGAAGAACGTTTTCAACCAGACGCACCAGAAGACGGGCA
GCCAGCCGGAGACGCTCGCGAAGGCGGTCTACGCGTACGCGGCGAACATCGACAATCTCGGCGCGCTCGGCGGTGCCGTG
TCGCGGATCGCGCACAAGCACGCGAGCCTGAACATCCGGCCGGAGCACTATCCGATCGTCGGCGAGAACCTGCTCGCGTC
GATCGTCGAGGTGCTCGGCGACGCGGTGGACGCGCACACGCTCGAAGCGTGGCGCATCGCGTACGGCCAACTGGCGACGA
TCCTGATCGGCGCGGAGGCGAACCTGTACGAGAACGCCGCATGGAGCGGTTTCCGTCCGTTCAAGGTCGCGAAGAAGGTG
CGCGAGAGCGACGAGATCACGTCGTTCTACCTGACGCCCGCCGACGGCGGCGCGGCGCCCGAGTTCGCGCCGGGCCAGTA
CATCTCGGTGAAGCGCTTCGTCGGCGACATGGGCGTCGAGCAGCCGCGGCAGTACAGCCTGTCCGACGCGCCCCACGGCA
AGTGGCTGCGCATCTCGGTCAAGCGCGAAGCGGGGCGCAGCGAGGAAGTGCCGGCGGGCAAGGTGTCGACGCTGATGCAC
GACGGCGTCGACGTCGATTCGATCGTCGAAGTCACCGCGCCGATGGGCGATTTCACGCTGAACCGCGACGCGTCGACGCC
TGTCGTGCTGATTTCGGGCGGCGTCGGGATCACGCCGATGATGTCGATGGCGTCGACGCTCGTCGCGTCGGGCAGCGAGC
GCGAAGTGCGGTTCCTGCACGCTTGCCGGTCGGCGAACGTGCACGCGTTTCGCGACTGGCTGAACGACACGACGGATGCC
CATCCGAACGTGAAGCGCACGGTGTTCTACGAGGAAGTCGGCCCGAACGACCGGGTCGGCGTCGATCACGACTACGAAGG
CCGGATCACGCCGGCCGCGCTCGAGCGCCACGCGCTCGTGCCGGACGCCGATTACTACATCTGCGGGCCGATTGCGTTCA
TGAAGCAGCAACGCGATGCGCTCGTCGCGCTCGGCGTCGCGCCGGAGCGCGTGCAGACGGAAATCTTCGGCTCGGGCGCG
CTCGAATGA

Upstream 100 bases:

>100_bases
GCAATCGCGGGCCTGTTGTGGCGAGGTGCGACAATTTGACCGCCGGGCGCGCGCCCATAAAGATGTATCGTTTGAGAATG
TTTAACGGAGGAATACTTTC

Downstream 100 bases:

>100_bases
AGGAACATCGGCGAACGGCACGCGTTCGCTGACGCAGAACGAAAAAGCCCGGCGCAACGCGTCGGGCTTTTTCTTGGGCA
ATGCTCGCCCGGAACGGTGC

Product: flavohemoprotein

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MTQMTAEQMARVKATAPVLAEHGATITKHFYQRMFGRHPELKNVFNQTHQKTGSQPETLAKAVYAYAANIDNLGALGGAV
SRIAHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDAHTLEAWRIAYGQLATILIGAEANLYENAAWSGFRPFKVAKKV
RESDEITSFYLTPADGGAAPEFAPGQYISVKRFVGDMGVEQPRQYSLSDAPHGKWLRISVKREAGRSEEVPAGKVSTLMH
DGVDVDSIVEVTAPMGDFTLNRDASTPVVLISGGVGITPMMSMASTLVASGSEREVRFLHACRSANVHAFRDWLNDTTDA
HPNVKRTVFYEEVGPNDRVGVDHDYEGRITPAALERHALVPDADYYICGPIAFMKQQRDALVALGVAPERVQTEIFGSGA
LE

Sequences:

>Translated_402_residues
MTQMTAEQMARVKATAPVLAEHGATITKHFYQRMFGRHPELKNVFNQTHQKTGSQPETLAKAVYAYAANIDNLGALGGAV
SRIAHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDAHTLEAWRIAYGQLATILIGAEANLYENAAWSGFRPFKVAKKV
RESDEITSFYLTPADGGAAPEFAPGQYISVKRFVGDMGVEQPRQYSLSDAPHGKWLRISVKREAGRSEEVPAGKVSTLMH
DGVDVDSIVEVTAPMGDFTLNRDASTPVVLISGGVGITPMMSMASTLVASGSEREVRFLHACRSANVHAFRDWLNDTTDA
HPNVKRTVFYEEVGPNDRVGVDHDYEGRITPAALERHALVPDADYYICGPIAFMKQQRDALVALGVAPERVQTEIFGSGA
LE
>Mature_401_residues
TQMTAEQMARVKATAPVLAEHGATITKHFYQRMFGRHPELKNVFNQTHQKTGSQPETLAKAVYAYAANIDNLGALGGAVS
RIAHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDAHTLEAWRIAYGQLATILIGAEANLYENAAWSGFRPFKVAKKVR
ESDEITSFYLTPADGGAAPEFAPGQYISVKRFVGDMGVEQPRQYSLSDAPHGKWLRISVKREAGRSEEVPAGKVSTLMHD
GVDVDSIVEVTAPMGDFTLNRDASTPVVLISGGVGITPMMSMASTLVASGSEREVRFLHACRSANVHAFRDWLNDTTDAH
PNVKRTVFYEEVGPNDRVGVDHDYEGRITPAALERHALVPDADYYICGPIAFMKQQRDALVALGVAPERVQTEIFGSGAL
E

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=399, Percent_Identity=42.3558897243108, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1787658, Length=258, Percent_Identity=26.3565891472868, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788104, Length=253, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321673, Length=405, Percent_Identity=37.037037037037, Blast_Score=239, Evalue=4e-64,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 43809; Mature: 43678

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQMTAEQMARVKATAPVLAEHGATITKHFYQRMFGRHPELKNVFNQTHQKTGSQPETLA
CCCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHH
KAVYAYAANIDNLGALGGAVSRIAHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDAHT
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
LEAWRIAYGQLATILIGAEANLYENAAWSGFRPFKVAKKVRESDEITSFYLTPADGGAAP
HHHHHHHHHCEEEEEEECCCCHHCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCC
EFAPGQYISVKRFVGDMGVEQPRQYSLSDAPHGKWLRISVKREAGRSEEVPAGKVSTLMH
CCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHH
DGVDVDSIVEVTAPMGDFTLNRDASTPVVLISGGVGITPMMSMASTLVASGSEREVRFLH
CCCCHHHHHHHHCCCCCEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHH
ACRSANVHAFRDWLNDTTDAHPNVKRTVFYEEVGPNDRVGVDHDYEGRITPAALERHALV
HHHCCCHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCC
PDADYYICGPIAFMKQQRDALVALGVAPERVQTEIFGSGALE
CCCCEEEECHHHHHHHHCCEEEEECCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQMTAEQMARVKATAPVLAEHGATITKHFYQRMFGRHPELKNVFNQTHQKTGSQPETLA
CCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHH
KAVYAYAANIDNLGALGGAVSRIAHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDAHT
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
LEAWRIAYGQLATILIGAEANLYENAAWSGFRPFKVAKKVRESDEITSFYLTPADGGAAP
HHHHHHHHHCEEEEEEECCCCHHCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCC
EFAPGQYISVKRFVGDMGVEQPRQYSLSDAPHGKWLRISVKREAGRSEEVPAGKVSTLMH
CCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHH
DGVDVDSIVEVTAPMGDFTLNRDASTPVVLISGGVGITPMMSMASTLVASGSEREVRFLH
CCCCHHHHHHHHCCCCCEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHH
ACRSANVHAFRDWLNDTTDAHPNVKRTVFYEEVGPNDRVGVDHDYEGRITPAALERHALV
HHHCCCHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCC
PDADYYICGPIAFMKQQRDALVALGVAPERVQTEIFGSGALE
CCCCEEEECHHHHHHHHCCEEEEECCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]