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The map label for this gene is mntH [H]

Identifier: 83720381

GI number: 83720381

Start: 2562181

End: 2563743

Strand: Reverse

Name: mntH [H]

Synonym: BTH_I2275

Alternate gene names: 83720381

Gene position: 2563743-2562181 (Counterclockwise)

Preceding gene: 83719558

Following gene: 83720609

Centisome position: 67.3

GC content: 70.57

Gene sequence:

>1563_bases
TTGTCGCACAAACGGAACACATTTGCACTTTTCGATTGCACGGCGGGGCGCCGCGACGCGGCAGGTGGGCGCAATTTTAT
CGGGTTATCGGCGCGTGTCCATCCTGAAAAAAGGCCCGCGCAGGCCGAACGGATCACCTACCCTAAATTCAGGCGGCGCC
CGTTCGTCGTTTCGGATAGGAGGACGCGCGCCCCGCCCGTCCGAACGCCGCGCCCGCCGCCCGGCCGCGTGCGTCAAACC
GTTCGCCGGACCGCCATCATGAACAGTCGCCCGCTTGCCGTCCGCCGTGCATCGCGCCGCCCGTCCGCCTCCGGCGGGCC
GGGCGGCGGCGGCCGCTGGGCCGCGTTCGTCGGCGCGGGCGTGCTCGTCGCCGTCGGCTACATGGACCCCGGCAACTGGG
CGACCGCGCTCGCAGGCGGCGCAGGCTACGGCTACGCACTTCTCGGCGTCGTGATCGCCGCGAGCCTGATGGCGATGCTG
CTGCAATGGCTCGCCGCGCGGATCGGCGTCGTGTCCGGGCGCGACCTCGCGCAACTGTGCCGCGAACGCTTCGACCCGCG
CGCGACGGTGCCGCTGTGGATCGCCGCCGAAATCGCGATCGTCGCCTGCGACGTCGCCGAGGTCGTCGGCGCGGCGGTCG
CGCTGCAAATGCTGCTCGGCGTATCGCTGACGGCGGGCGTGCTCATATCGGCGATCGCAACGCTCGCGATGCTCGCGCTC
GAGCGGCATGGCCGGCGCACGCTCGAGGCGGCGATCGCGTCGCTCATCCTTTTCGTCGGCCTCTGCTTCGTGATCGAGGT
CGCGCTTGCGCGGCCCGACTGGCACGCGGCGCTCGCGGGCGCCGCGCCGTCGCCGCGGCTGCTGCGCGAGCCCGGCATGC
TGTGGCTCGCGGCCGGCATCCTCGGCGCGACCGTGATGCCGCACAACCTCTATCTGCACTCGATGCTCGTCAAGCACCAC
GCAAGCGAACGCGACGAGCAGTCGATCCGGCGCGCGCTGTTCGGCGTCAATCTCGATACGTTCGTGTCGCTCGGCTTCGC
GTTCGTGATCAACGCGGCGCTTCTCATCGTCGCGGCGGCGGTGTTCCATGCGAGCGGCCACGACGAGGTCACCGATCTCG
CCGATGCGCACCGGCTCATCGCACCGCTCGTCGGCAACCACTGGGCAGGCCTGCTGTTCGCGGCCGCGCTGCTCGCGTGC
GGACTGTCGGCGACGGTGACGGGCACGCTTGCCGGGCAAGCGATCATGGAAGGGTTCCTGAAGCTCTCGCTGCCGCGCTG
GCAGCGCGCGCTCCTCACCCGCGCGCTCGCGATCGGCCCGGCGCTCGCCGCGGTCGGCCTGTTCGGGCAGCACGGATCGA
ATCAGTTGCTCGTCGCGAGCCAGGTCGTGCTGAGCCTGCAATTGCCGCTCGCAATGGTTCCGCTCATCGTGTTCGCGTCG
AGCCGCGCGCTAATGGGAAACTGGCGTGTCCGCGGCTTGCCGCTCGCCGCCGCATGGGCGTGCGCCGCCGTGATTCTGCT
GCTGAACGGGGCGCTCGTCTGGCAGATCGCCGCGGCGCAGTGA

Upstream 100 bases:

>100_bases
TCGCCGTCAGCCTCGCCACTGCGGCGCACCGTTTCGCGCCGCCCCTTGAAAACCCCGAAAGCTACCACTAATCCGGCCCC
GCCACAAAAATTTCCCGCTT

Downstream 100 bases:

>100_bases
GCGGCGCAATCGGCGCAATCGAGGCGACCCGGGCAACCGGGGCGATTTGCGACCGCACGCCACGCATGCGCGCCCCGGGC
TGCCCCGAGCAGCTGCGCCA

Product: manganese/iron transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MSHKRNTFALFDCTAGRRDAAGGRNFIGLSARVHPEKRPAQAERITYPKFRRRPFVVSDRRTRAPPVRTPRPPPGRVRQT
VRRTAIMNSRPLAVRRASRRPSASGGPGGGGRWAAFVGAGVLVAVGYMDPGNWATALAGGAGYGYALLGVVIAASLMAML
LQWLAARIGVVSGRDLAQLCRERFDPRATVPLWIAAEIAIVACDVAEVVGAAVALQMLLGVSLTAGVLISAIATLAMLAL
ERHGRRTLEAAIASLILFVGLCFVIEVALARPDWHAALAGAAPSPRLLREPGMLWLAAGILGATVMPHNLYLHSMLVKHH
ASERDEQSIRRALFGVNLDTFVSLGFAFVINAALLIVAAAVFHASGHDEVTDLADAHRLIAPLVGNHWAGLLFAAALLAC
GLSATVTGTLAGQAIMEGFLKLSLPRWQRALLTRALAIGPALAAVGLFGQHGSNQLLVASQVVLSLQLPLAMVPLIVFAS
SRALMGNWRVRGLPLAAAWACAAVILLLNGALVWQIAAAQ

Sequences:

>Translated_520_residues
MSHKRNTFALFDCTAGRRDAAGGRNFIGLSARVHPEKRPAQAERITYPKFRRRPFVVSDRRTRAPPVRTPRPPPGRVRQT
VRRTAIMNSRPLAVRRASRRPSASGGPGGGGRWAAFVGAGVLVAVGYMDPGNWATALAGGAGYGYALLGVVIAASLMAML
LQWLAARIGVVSGRDLAQLCRERFDPRATVPLWIAAEIAIVACDVAEVVGAAVALQMLLGVSLTAGVLISAIATLAMLAL
ERHGRRTLEAAIASLILFVGLCFVIEVALARPDWHAALAGAAPSPRLLREPGMLWLAAGILGATVMPHNLYLHSMLVKHH
ASERDEQSIRRALFGVNLDTFVSLGFAFVINAALLIVAAAVFHASGHDEVTDLADAHRLIAPLVGNHWAGLLFAAALLAC
GLSATVTGTLAGQAIMEGFLKLSLPRWQRALLTRALAIGPALAAVGLFGQHGSNQLLVASQVVLSLQLPLAMVPLIVFAS
SRALMGNWRVRGLPLAAAWACAAVILLLNGALVWQIAAAQ
>Mature_519_residues
SHKRNTFALFDCTAGRRDAAGGRNFIGLSARVHPEKRPAQAERITYPKFRRRPFVVSDRRTRAPPVRTPRPPPGRVRQTV
RRTAIMNSRPLAVRRASRRPSASGGPGGGGRWAAFVGAGVLVAVGYMDPGNWATALAGGAGYGYALLGVVIAASLMAMLL
QWLAARIGVVSGRDLAQLCRERFDPRATVPLWIAAEIAIVACDVAEVVGAAVALQMLLGVSLTAGVLISAIATLAMLALE
RHGRRTLEAAIASLILFVGLCFVIEVALARPDWHAALAGAAPSPRLLREPGMLWLAAGILGATVMPHNLYLHSMLVKHHA
SERDEQSIRRALFGVNLDTFVSLGFAFVINAALLIVAAAVFHASGHDEVTDLADAHRLIAPLVGNHWAGLLFAAALLACG
LSATVTGTLAGQAIMEGFLKLSLPRWQRALLTRALAIGPALAAVGLFGQHGSNQLLVASQVVLSLQLPLAMVPLIVFASS
RALMGNWRVRGLPLAAAWACAAVILLLNGALVWQIAAAQ

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI295293167, Length=413, Percent_Identity=36.5617433414044, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI295293178, Length=413, Percent_Identity=36.5617433414044, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI295293175, Length=413, Percent_Identity=36.5617433414044, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI295293173, Length=413, Percent_Identity=36.5617433414044, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI10835169, Length=413, Percent_Identity=36.5617433414044, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI295293171, Length=413, Percent_Identity=36.5617433414044, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI295293169, Length=413, Percent_Identity=36.5617433414044, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI109255241, Length=401, Percent_Identity=36.1596009975062, Blast_Score=198, Evalue=1e-50,
Organism=Escherichia coli, GI1788736, Length=414, Percent_Identity=38.4057971014493, Blast_Score=254, Evalue=7e-69,
Organism=Caenorhabditis elegans, GI193210616, Length=425, Percent_Identity=33.6470588235294, Blast_Score=207, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17569473, Length=375, Percent_Identity=34.6666666666667, Blast_Score=205, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI71999499, Length=434, Percent_Identity=31.5668202764977, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI71993856, Length=206, Percent_Identity=38.3495145631068, Blast_Score=137, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6323062, Length=394, Percent_Identity=39.3401015228426, Blast_Score=248, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6321841, Length=434, Percent_Identity=35.2534562211982, Blast_Score=217, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6324450, Length=423, Percent_Identity=32.8605200945626, Blast_Score=204, Evalue=3e-53,
Organism=Drosophila melanogaster, GI45553443, Length=413, Percent_Identity=34.6246973365617, Blast_Score=211, Evalue=9e-55,
Organism=Drosophila melanogaster, GI24648607, Length=413, Percent_Identity=34.6246973365617, Blast_Score=211, Evalue=9e-55,
Organism=Drosophila melanogaster, GI281362176, Length=413, Percent_Identity=34.6246973365617, Blast_Score=211, Evalue=9e-55,
Organism=Drosophila melanogaster, GI24648609, Length=413, Percent_Identity=34.6246973365617, Blast_Score=211, Evalue=9e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 54983; Mature: 54851

Theoretical pI: Translated: 11.86; Mature: 11.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHKRNTFALFDCTAGRRDAAGGRNFIGLSARVHPEKRPAQAERITYPKFRRRPFVVSDR
CCCCCCEEEEEECCCCCCCCCCCCCEEEECEEECCCCCCCCHHHCCCHHHHCCCCEECCC
RTRAPPVRTPRPPPGRVRQTVRRTAIMNSRPLAVRRASRRPSASGGPGGGGRWAAFVGAG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHCC
VLVAVGYMDPGNWATALAGGAGYGYALLGVVIAASLMAMLLQWLAARIGVVSGRDLAQLC
HHEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RERFDPRATVPLWIAAEIAIVACDVAEVVGAAVALQMLLGVSLTAGVLISAIATLAMLAL
HHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERHGRRTLEAAIASLILFVGLCFVIEVALARPDWHAALAGAAPSPRLLREPGMLWLAAGI
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHCCCHHHHHHHH
LGATVMPHNLYLHSMLVKHHASERDEQSIRRALFGVNLDTFVSLGFAFVINAALLIVAAA
HHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VFHASGHDEVTDLADAHRLIAPLVGNHWAGLLFAAALLACGLSATVTGTLAGQAIMEGFL
HHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KLSLPRWQRALLTRALAIGPALAAVGLFGQHGSNQLLVASQVVLSLQLPLAMVPLIVFAS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHC
SRALMGNWRVRGLPLAAAWACAAVILLLNGALVWQIAAAQ
CCHHCCCCEECCCCHHHHHHHHHHHHHHCCHHEEEEECCC
>Mature Secondary Structure 
SHKRNTFALFDCTAGRRDAAGGRNFIGLSARVHPEKRPAQAERITYPKFRRRPFVVSDR
CCCCCEEEEEECCCCCCCCCCCCCEEEECEEECCCCCCCCHHHCCCHHHHCCCCEECCC
RTRAPPVRTPRPPPGRVRQTVRRTAIMNSRPLAVRRASRRPSASGGPGGGGRWAAFVGAG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHCC
VLVAVGYMDPGNWATALAGGAGYGYALLGVVIAASLMAMLLQWLAARIGVVSGRDLAQLC
HHEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RERFDPRATVPLWIAAEIAIVACDVAEVVGAAVALQMLLGVSLTAGVLISAIATLAMLAL
HHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERHGRRTLEAAIASLILFVGLCFVIEVALARPDWHAALAGAAPSPRLLREPGMLWLAAGI
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHCCCHHHHHHHH
LGATVMPHNLYLHSMLVKHHASERDEQSIRRALFGVNLDTFVSLGFAFVINAALLIVAAA
HHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VFHASGHDEVTDLADAHRLIAPLVGNHWAGLLFAAALLACGLSATVTGTLAGQAIMEGFL
HHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KLSLPRWQRALLTRALAIGPALAAVGLFGQHGSNQLLVASQVVLSLQLPLAMVPLIVFAS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHC
SRALMGNWRVRGLPLAAAWACAAVILLLNGALVWQIAAAQ
CCHHCCCCEECCCCHHHHHHHHHHHHHHCCHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]