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The map label for this gene is emrY [H]

Identifier: 83720062

GI number: 83720062

Start: 2490569

End: 2492125

Strand: Reverse

Name: emrY [H]

Synonym: BTH_I2215

Alternate gene names: 83720062

Gene position: 2492125-2490569 (Counterclockwise)

Preceding gene: 83720022

Following gene: 83720796

Centisome position: 65.42

GC content: 67.69

Gene sequence:

>1557_bases
ATGAGCGCCGCGCCGGGCCGGCCACCGCTCTGGAGCGCCGCGAACCTGCGCGGCGATATCTTTCCATGGGTGCTCGCGAT
CGTCACCGGACTCGACTACTTCGACAACGCGGCGTTCTCGTTCTTCGCGAGCTATATCGCGGGCGGCGTCAACGCGTCGC
CGGACGAGCTCGTGTGGGCGTCGAGCGCGTACGCGGTGGCGGCGGTGCTCGGCATCCTGCAGCAGCAATGGTGGGTCGAC
CGGCTCGGGCACCGGCGTTACGTCGCCGGCTGCATGCTGATGTTCTCGCTCGGCGCGGCGGCCGCGGCGCTTGCCGACAC
GTCGCTGCAGCTCGCGTTCGCGCGCGGCTTCCAGGGCTACTTCATCGGCCCGATGATGGGCGCGTGCCGGATCCTGATCC
AGACCAGCTTCGCGCCGAAGGATCGCCCGCCCGCGACGCGCGCGTTCCTCGTCATGCTGCTGCTCGGCAGCGCGATCGCG
CCGATCGCGGGCGGCCTGCTCGTCGCGCACTTCACGTGGCGCGCGCTGTTCGCGTGCACGGTGCCGACGGGCATCCTGTT
CGCGGCGCTCGCGTTCGTCGCGCTGCCGAATTCCGGCCACACGCCGCCCGACGAGCGCGGCGGCGCGCACTTCTGGCCGT
ACGTGATCTTCGCGCTCGCGCAAGGCGCGCTGCAGATCGTGATGCAGCAAGTGCGCTTCCAGCTTTTCGCCGGATCTCCG
CAGCTCGTGCTGCTCGCCGTCGGCGGCCTCGCGGCCCTCGCGTGGTTCGGCTATCACCAGTGGCATCATCCGGCGCCGCT
CGTGCGGCTGCACGCGTTTCGCGAGCGCACGTTCCAGGTCGGGCTGCTGCTCTACATGTTCTACTACTACGAAACGACGG
GCTACAGCTATCTGATCTCCCGCTTTCTCGAAACCGGGCTCGGCTATCCGGTCGAGAACGCCGGGCGGCTCGTCGGCACG
ATGTCGCTGATTTCCGCGAGCGCGCTCTTCGTCTATCTGCGCTACGCGAAGCTGCTCACGCACAAGAAATGGATCATCGT
GCCCGGCTTCGCGCTCGCCGCGTTCGCCGCGCTGTGGATGACGCGGATGTCGCCCGAGGCCGGCGAAGCGGCGCTCGTCG
CGCCGCTCCTGATGCGCGGGCTGCTGCTCCTCTTCATCGTGCTGCCCGTCGCGAACCTGACGTTCCGCATATTCGCGATC
GACGAGTATTCGCACGGCTACCGGCTGAAGAATATCGTCCGGCAACTGACGATTTCGTTTGCGACCGCGTCCGTCATCAT
CGTCGAGCAGCATCGGCTCGCCGTGCACGAGACGCGGCTCGTCGAACGGGCGAACGTCTACAATCCGCTGTTCCAGCAAA
CCGTCGACACGCTCACGCGCGGCTTCGCGGCCGCGGGCCACGCACTGTCCGACGCGCACGCGCTCGCGCTCGTCACCGTG
AGCCGCACGATCGCGCAACAGGCATCGTTCCTGTCATCGCTCGACGGCTTCTACTTTCTCGCGGGCGTCGCGATCTGCGG
CGGCCTCTTCGCCGCCTGGCAAAAAGAGATCGATTGA

Upstream 100 bases:

>100_bases
TCGACTACGTCGAGCGCCGGCTCGCCGGCGAAAGCCCCGACGAACTGATCGCGCAGCGCCGCGCCGCCGCGCACGGGCGC
AAGACGGGCGGGACGGGCGC

Downstream 100 bases:

>100_bases
GGTACGTTTAGCGCCTGTCGCTTCACGCCCTTTCCGCCGCGATGCTCTCCAAACTCAACCAATGGCTCGACGCGCGCCGC
CGCGATCGCGCGCTGCGCGC

Product: multidrug resistance protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MSAAPGRPPLWSAANLRGDIFPWVLAIVTGLDYFDNAAFSFFASYIAGGVNASPDELVWASSAYAVAAVLGILQQQWWVD
RLGHRRYVAGCMLMFSLGAAAAALADTSLQLAFARGFQGYFIGPMMGACRILIQTSFAPKDRPPATRAFLVMLLLGSAIA
PIAGGLLVAHFTWRALFACTVPTGILFAALAFVALPNSGHTPPDERGGAHFWPYVIFALAQGALQIVMQQVRFQLFAGSP
QLVLLAVGGLAALAWFGYHQWHHPAPLVRLHAFRERTFQVGLLLYMFYYYETTGYSYLISRFLETGLGYPVENAGRLVGT
MSLISASALFVYLRYAKLLTHKKWIIVPGFALAAFAALWMTRMSPEAGEAALVAPLLMRGLLLLFIVLPVANLTFRIFAI
DEYSHGYRLKNIVRQLTISFATASVIIVEQHRLAVHETRLVERANVYNPLFQQTVDTLTRGFAAAGHALSDAHALALVTV
SRTIAQQASFLSSLDGFYFLAGVAICGGLFAAWQKEID

Sequences:

>Translated_518_residues
MSAAPGRPPLWSAANLRGDIFPWVLAIVTGLDYFDNAAFSFFASYIAGGVNASPDELVWASSAYAVAAVLGILQQQWWVD
RLGHRRYVAGCMLMFSLGAAAAALADTSLQLAFARGFQGYFIGPMMGACRILIQTSFAPKDRPPATRAFLVMLLLGSAIA
PIAGGLLVAHFTWRALFACTVPTGILFAALAFVALPNSGHTPPDERGGAHFWPYVIFALAQGALQIVMQQVRFQLFAGSP
QLVLLAVGGLAALAWFGYHQWHHPAPLVRLHAFRERTFQVGLLLYMFYYYETTGYSYLISRFLETGLGYPVENAGRLVGT
MSLISASALFVYLRYAKLLTHKKWIIVPGFALAAFAALWMTRMSPEAGEAALVAPLLMRGLLLLFIVLPVANLTFRIFAI
DEYSHGYRLKNIVRQLTISFATASVIIVEQHRLAVHETRLVERANVYNPLFQQTVDTLTRGFAAAGHALSDAHALALVTV
SRTIAQQASFLSSLDGFYFLAGVAICGGLFAAWQKEID
>Mature_517_residues
SAAPGRPPLWSAANLRGDIFPWVLAIVTGLDYFDNAAFSFFASYIAGGVNASPDELVWASSAYAVAAVLGILQQQWWVDR
LGHRRYVAGCMLMFSLGAAAAALADTSLQLAFARGFQGYFIGPMMGACRILIQTSFAPKDRPPATRAFLVMLLLGSAIAP
IAGGLLVAHFTWRALFACTVPTGILFAALAFVALPNSGHTPPDERGGAHFWPYVIFALAQGALQIVMQQVRFQLFAGSPQ
LVLLAVGGLAALAWFGYHQWHHPAPLVRLHAFRERTFQVGLLLYMFYYYETTGYSYLISRFLETGLGYPVENAGRLVGTM
SLISASALFVYLRYAKLLTHKKWIIVPGFALAAFAALWMTRMSPEAGEAALVAPLLMRGLLLLFIVLPVANLTFRIFAID
EYSHGYRLKNIVRQLTISFATASVIIVEQHRLAVHETRLVERANVYNPLFQQTVDTLTRGFAAAGHALSDAHALALVTVS
RTIAQQASFLSSLDGFYFLAGVAICGGLFAAWQKEID

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1788710, Length=477, Percent_Identity=20.9643605870021, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1789042, Length=484, Percent_Identity=20.6611570247934, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790195, Length=411, Percent_Identity=24.0875912408759, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87081983, Length=301, Percent_Identity=25.2491694352159, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 56541; Mature: 56410

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAAPGRPPLWSAANLRGDIFPWVLAIVTGLDYFDNAAFSFFASYIAGGVNASPDELVWA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEC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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]