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The map label for this gene is wbpM [H]

Identifier: 83719442

GI number: 83719442

Start: 1680085

End: 1682055

Strand: Direct

Name: wbpM [H]

Synonym: BTH_I1483

Alternate gene names: 83719442

Gene position: 1680085-1682055 (Clockwise)

Preceding gene: 83718571

Following gene: 83720904

Centisome position: 44.11

GC content: 64.64

Gene sequence:

>1971_bases
TTGGGGCAGCCATCGACGTTCGCTGGAGCCGCTTCCAAATACTCACATCAAAATAAACGCAATATGACGCGAACGTTTCG
CCCCAAGGCTTCATGGCTTTCCCTGGGCGCCTTCCTGTTCGACTTGATGGCGGTCGTATGCGCATGGTTGATCGCATACG
TGGTTCGATTCAACGGTGTAATACCGCCCCAATTCCTGAGCGGCGCCTTCGTCGCGCTCGTATGGGTGGTTCCGTTGTAC
GGTCTGCTGTTTCATGTTTTCGGCTTGTACCGCGGCCTCTGGGTATTCGCGAGCCTGCCGGATCTGCTGCGCATCTCGAA
GGCCGTGGTGGGCGGCAGCCTGATCGTAATGATCGGCGCGGTAATGCTACAGCCGGTTCCGATCATTCCCCGTTCGGTGC
TTGTCCTGTCGCCGATGCTGCTGTTTCTCGCGATGGGCGGCGCGCGGGCGCTCTATCGGGCGACGAAGGAGTTCTATCTA
TACGGCGGCTTGATCGGGCAGGGCAAGCCGGTGCTGATTCTCGGCGCGGGCAACGCCGGCGCGAGTCTCGCCCGTGAGCT
GTCTCGTTCCGGCGAATGGCGCCTTGCCGGTTTGCTCGACGACGATCCCGCAAAACACGGCCGTGAAGTCTACGGCTACA
AAGTCCTTGGCCCCATCAGCGAAGTCGCGCACTGGGCCGAGGCAGCAAAAGCCGAATACGCGATCATCGCGATTCCATCC
GCATCGGTCGAGACGCAACGCCGCGTCGCCACCCTCTGCGTGCGCGCCGGCGTCAAGGCGATGGTGCTGCCGTCGCTGAC
CGCATTGATGCCCGGCCAAGGCATCCTGTCGCAGATCCGCCAGATCGACCTCGAAGACCTGCTCGGCCGCGAGGCCGTGA
CGATCGACACGCCGCACGTCGAAGCGCTGTTGCGCGGCCGCGTCGTGATGGTGACGGGCGCAGGCGGCTCGATCGGCTCG
GAGCTGTGCCGCCAGATCCTGAAGTTCCAGCCCGCGCAACTGATCGCGTTCGACCTGTCCGAATATGCGATGTACCGTCT
CACGGAAGAGTTGCGCGAGCGCTTCCCCGATCTGCCCGTCGTGCCGATCATCGGCGATGCGAAGGATTCGCTGCTGCTCG
ACCAGGTGATGTCGCGCTACGCGCCGCACATCGTGTTCCATGCGGCCGCGTACAAGCACGTGCCGCTGATGGAGGAGCTC
AACGCGTGGCAGGCGTTGCGCAACAACGTGCTCGGCACCTATCGCGTCGCGCGCGCGGCGATTCGCCACGACGTCCGGCA
TTTCGTGCTGATCTCGACCGACAAGGCCGTGAACCCGACGAACGTGATGGGCGCGAGCAAGCGCTTGGCCGAGATGGCGT
GTCAGGCGCTGCAGCAGACGAGCGCGCGCACGCAGTTCGAGACGGTGCGCTTCGGCAACGTGCTAGGCAGCGCGGGCAGC
GTGATTCCGAAGTTCCAGCAGCAGATCGCGAAGGGCGGCCCGGTGACGGTCACGCATCCGGAGATCACGCGCTTCTTCAT
GACGATTCCCGAGGCGTCGCAGCTCGTGCTGCAGGCGTCGAGCATGGGGCAGGGCGGCGAGATCTTCATTCTCGACATGG
GCGAGCCGGTGAAGATCGTCGATCTCGCGCGCGACCTGATCCGCCTTTACGGCTTTACCGAGGACCACATCCGCATCGAG
TTCAGCGGGCTGCGTCCGGGCGAGAAGCTCTACGAGGAACTGCTCGCCGACGACGAGACGACAACCCGCACGCCGCATCC
GAAGCTGCGCACGGCGCGTGCGCGCGAGGTGCCGGATCATCTGCTCGACGAACTGCTGCCGTGGCTGATGCAGCACCGAG
TGCTGAGCGATGACGAAGTGCGGCGCGATCTGCGGCGCTGGGTGCCCGAGTATCAACCCGCCGTCGGCCCGACGCTGCAG
AGCGTGCCGACCGGCAGCGGGCTGGTCGCCGGCCTCGGTCGCGACGCCTGA

Upstream 100 bases:

>100_bases
ATCATGCTGGTTGGCGCCGTTGTGTCGCTTTCAGTGTTGACGAGTTCTCCCGCGATCCAGTGGATGAGCATCGCCATTTG
GGGATTGATTCTATTTCTCA

Downstream 100 bases:

>100_bases
CGCTACAAGGAAGGCACAAGGAAGGCGAGACGGTTCCGGCCGGGATGCTGTCGAAGTCGGCCCGCACGTCCGCCGCCCGG
GCGGCGGCAAGGCCGAGGGC

Product: capsular polysaccharide biosynthesis

Products: UDPglucoseal [C]

Alternate protein names: NA

Number of amino acids: Translated: 656; Mature: 655

Protein sequence:

>656_residues
MGQPSTFAGAASKYSHQNKRNMTRTFRPKASWLSLGAFLFDLMAVVCAWLIAYVVRFNGVIPPQFLSGAFVALVWVVPLY
GLLFHVFGLYRGLWVFASLPDLLRISKAVVGGSLIVMIGAVMLQPVPIIPRSVLVLSPMLLFLAMGGARALYRATKEFYL
YGGLIGQGKPVLILGAGNAGASLARELSRSGEWRLAGLLDDDPAKHGREVYGYKVLGPISEVAHWAEAAKAEYAIIAIPS
ASVETQRRVATLCVRAGVKAMVLPSLTALMPGQGILSQIRQIDLEDLLGREAVTIDTPHVEALLRGRVVMVTGAGGSIGS
ELCRQILKFQPAQLIAFDLSEYAMYRLTEELRERFPDLPVVPIIGDAKDSLLLDQVMSRYAPHIVFHAAAYKHVPLMEEL
NAWQALRNNVLGTYRVARAAIRHDVRHFVLISTDKAVNPTNVMGASKRLAEMACQALQQTSARTQFETVRFGNVLGSAGS
VIPKFQQQIAKGGPVTVTHPEITRFFMTIPEASQLVLQASSMGQGGEIFILDMGEPVKIVDLARDLIRLYGFTEDHIRIE
FSGLRPGEKLYEELLADDETTTRTPHPKLRTARAREVPDHLLDELLPWLMQHRVLSDDEVRRDLRRWVPEYQPAVGPTLQ
SVPTGSGLVAGLGRDA

Sequences:

>Translated_656_residues
MGQPSTFAGAASKYSHQNKRNMTRTFRPKASWLSLGAFLFDLMAVVCAWLIAYVVRFNGVIPPQFLSGAFVALVWVVPLY
GLLFHVFGLYRGLWVFASLPDLLRISKAVVGGSLIVMIGAVMLQPVPIIPRSVLVLSPMLLFLAMGGARALYRATKEFYL
YGGLIGQGKPVLILGAGNAGASLARELSRSGEWRLAGLLDDDPAKHGREVYGYKVLGPISEVAHWAEAAKAEYAIIAIPS
ASVETQRRVATLCVRAGVKAMVLPSLTALMPGQGILSQIRQIDLEDLLGREAVTIDTPHVEALLRGRVVMVTGAGGSIGS
ELCRQILKFQPAQLIAFDLSEYAMYRLTEELRERFPDLPVVPIIGDAKDSLLLDQVMSRYAPHIVFHAAAYKHVPLMEEL
NAWQALRNNVLGTYRVARAAIRHDVRHFVLISTDKAVNPTNVMGASKRLAEMACQALQQTSARTQFETVRFGNVLGSAGS
VIPKFQQQIAKGGPVTVTHPEITRFFMTIPEASQLVLQASSMGQGGEIFILDMGEPVKIVDLARDLIRLYGFTEDHIRIE
FSGLRPGEKLYEELLADDETTTRTPHPKLRTARAREVPDHLLDELLPWLMQHRVLSDDEVRRDLRRWVPEYQPAVGPTLQ
SVPTGSGLVAGLGRDA
>Mature_655_residues
GQPSTFAGAASKYSHQNKRNMTRTFRPKASWLSLGAFLFDLMAVVCAWLIAYVVRFNGVIPPQFLSGAFVALVWVVPLYG
LLFHVFGLYRGLWVFASLPDLLRISKAVVGGSLIVMIGAVMLQPVPIIPRSVLVLSPMLLFLAMGGARALYRATKEFYLY
GGLIGQGKPVLILGAGNAGASLARELSRSGEWRLAGLLDDDPAKHGREVYGYKVLGPISEVAHWAEAAKAEYAIIAIPSA
SVETQRRVATLCVRAGVKAMVLPSLTALMPGQGILSQIRQIDLEDLLGREAVTIDTPHVEALLRGRVVMVTGAGGSIGSE
LCRQILKFQPAQLIAFDLSEYAMYRLTEELRERFPDLPVVPIIGDAKDSLLLDQVMSRYAPHIVFHAAAYKHVPLMEELN
AWQALRNNVLGTYRVARAAIRHDVRHFVLISTDKAVNPTNVMGASKRLAEMACQALQQTSARTQFETVRFGNVLGSAGSV
IPKFQQQIAKGGPVTVTHPEITRFFMTIPEASQLVLQASSMGQGGEIFILDMGEPVKIVDLARDLIRLYGFTEDHIRIEF
SGLRPGEKLYEELLADDETTTRTPHPKLRTARAREVPDHLLDELLPWLMQHRVLSDDEVRRDLRRWVPEYQPAVGPTLQS
VPTGSGLVAGLGRDA

Specific function: Required for the biosynthesis of type 1 capsular polysaccharide [H]

COG id: COG1086

COG function: function code MG; Predicted nucleoside-diphosphate sugar epimerases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR003869 [H]

Pfam domain/function: PF02719 Polysacc_synt_2 [H]

EC number: 5.1.3.2 [C]

Molecular weight: Translated: 72093; Mature: 71962

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQPSTFAGAASKYSHQNKRNMTRTFRPKASWLSLGAFLFDLMAVVCAWLIAYVVRFNGV
CCCCCCCHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IPPQFLSGAFVALVWVVPLYGLLFHVFGLYRGLWVFASLPDLLRISKAVVGGSLIVMIGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHH
VMLQPVPIIPRSVLVLSPMLLFLAMGGARALYRATKEFYLYGGLIGQGKPVLILGAGNAG
HHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCEECCCCCEEEEECCCCC
ASLARELSRSGEWRLAGLLDDDPAKHGREVYGYKVLGPISEVAHWAEAAKAEYAIIAIPS
HHHHHHHHCCCCEEEEECCCCCCHHCCCCCCCEEECCHHHHHHHHHHHHCCCEEEEEECC
ASVETQRRVATLCVRAGVKAMVLPSLTALMPGQGILSQIRQIDLEDLLGREAVTIDTPHV
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHCCCCEEEECCHHH
EALLRGRVVMVTGAGGSIGSELCRQILKFQPAQLIAFDLSEYAMYRLTEELRERFPDLPV
HHHHCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VPIIGDAKDSLLLDQVMSRYAPHIVFHAAAYKHVPLMEELNAWQALRNNVLGTYRVARAA
EEEECCCHHHHHHHHHHHHHCCHHEEHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHH
IRHDVRHFVLISTDKAVNPTNVMGASKRLAEMACQALQQTSARTQFETVRFGNVLGSAGS
HHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VIPKFQQQIAKGGPVTVTHPEITRFFMTIPEASQLVLQASSMGQGGEIFILDMGEPVKIV
CCHHHHHHHHCCCCEEEECHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHH
DLARDLIRLYGFTEDHIRIEFSGLRPGEKLYEELLADDETTTRTPHPKLRTARAREVPDH
HHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHH
LLDELLPWLMQHRVLSDDEVRRDLRRWVPEYQPAVGPTLQSVPTGSGLVAGLGRDA
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GQPSTFAGAASKYSHQNKRNMTRTFRPKASWLSLGAFLFDLMAVVCAWLIAYVVRFNGV
CCCCCCHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IPPQFLSGAFVALVWVVPLYGLLFHVFGLYRGLWVFASLPDLLRISKAVVGGSLIVMIGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHH
VMLQPVPIIPRSVLVLSPMLLFLAMGGARALYRATKEFYLYGGLIGQGKPVLILGAGNAG
HHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCEECCCCCEEEEECCCCC
ASLARELSRSGEWRLAGLLDDDPAKHGREVYGYKVLGPISEVAHWAEAAKAEYAIIAIPS
HHHHHHHHCCCCEEEEECCCCCCHHCCCCCCCEEECCHHHHHHHHHHHHCCCEEEEEECC
ASVETQRRVATLCVRAGVKAMVLPSLTALMPGQGILSQIRQIDLEDLLGREAVTIDTPHV
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHCCCCEEEECCHHH
EALLRGRVVMVTGAGGSIGSELCRQILKFQPAQLIAFDLSEYAMYRLTEELRERFPDLPV
HHHHCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VPIIGDAKDSLLLDQVMSRYAPHIVFHAAAYKHVPLMEELNAWQALRNNVLGTYRVARAA
EEEECCCHHHHHHHHHHHHHCCHHEEHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHH
IRHDVRHFVLISTDKAVNPTNVMGASKRLAEMACQALQQTSARTQFETVRFGNVLGSAGS
HHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VIPKFQQQIAKGGPVTVTHPEITRFFMTIPEASQLVLQASSMGQGGEIFILDMGEPVKIV
CCHHHHHHHHCCCCEEEECHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHH
DLARDLIRLYGFTEDHIRIEFSGLRPGEKLYEELLADDETTTRTPHPKLRTARAREVPDH
HHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHH
LLDELLPWLMQHRVLSDDEVRRDLRRWVPEYQPAVGPTLQSVPTGSGLVAGLGRDA
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): 57600 [C]

Specific activity: 233.3

Km value (mM): 0.256 {UDPgalactose}} 0.225 {UDPgalactose}} 0.2 {UDPgalactose}} 0.18 {UDPgalactose}} 0.16 {UDPgalactose}} 0.14 {UDPgalactose}} 0.048 {UDPgalactose}} 0.026 {UDPgalactose}} [C]

Substrates: UDPglucose [C]

Specific reaction: UDPglucose <==> UDPglucoseal [C]

General reaction: Epimerization (specificity for carbon forming a hexosulose) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961465 [H]