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The map label for this gene is aroE [H]

Identifier: 83719204

GI number: 83719204

Start: 1316838

End: 1317710

Strand: Direct

Name: aroE [H]

Synonym: BTH_I1171

Alternate gene names: 83719204

Gene position: 1316838-1317710 (Clockwise)

Preceding gene: 83721664

Following gene: 83721431

Centisome position: 34.57

GC content: 72.51

Gene sequence:

>873_bases
ATGAGCGCGGCCGTCGAACCGCTCGTGCGCGATCGCTACGCGGTGATCGGCAATCCGGTCGCGCACAGTAAATCGCCGTT
CATTCATGCGCGCTTCGCCGAGCAGACGGGCGAGGCGATCGAATACACGCATCTGCTCGCGCCGCTCGACGGCTTCGCGG
CCACGGTGCGCGAATTCACCGCGCAGGGCGGCCGGGGCGTGAACGTCACCGTGCCGTTCAAGCTCGAGGCCTACGCGCTT
GCCGATACGCTGTCGCCGCGCGCGGCGGCGGCGGGCGCTGTCAACACGCTGCGCTTCGATGCGGACGGCATCTTCGGCGA
CAACACCGACGGCGTCGGCCTCGTGCGCGACATCGAGACGAATCTCGGCGTGAGCCTGACGGGCGCGCGGATCCTGCTGC
TCGGCGCGGGCGGCGCGGCGCGCGGCGTCGTGCTGCCGATGCTCGAGCGCGGGCCCGCGTCGCTCACGATCGTCAATCGG
ACCGCGAGCAAGGCGGAAGAACTCGTCGGCCAGTTCACGCAAGCGGCGCACGACGCGGGCTGCGTGCTCGCGGGCGGCGG
GCCCGAGCGGGTCGCGCGCGAGCCGTACGACGTGATCGTCAACGCGACGGCGGGCAGTCTCGACGCGGCGTTGCCCGAGT
GCGACGCCGCGGCGTTCTGCCCGGCGACGCTCGCGTACGACATGATGTACGGCGCGCGGCCGACCGTCTTCATGGAGCAT
GCGGCGACGCTCGGCGCGCGCACGGCGGACGGGCTCGGAATGCTCGTCGAGCAGGCAGCGGAATCGTTCTATCTCTGGCG
CGGCGTGCGGCCCGACGGCGCGCCCGTGCTCGCCGCGCTGCGCGCCGCACTCGCGGCGTCGGCGGCGCACTGA

Upstream 100 bases:

>100_bases
ACGCCGCCGACGAATCGGCGGAAAGCGAAGCGGAAGCGCTCGCCGAGGCGAGCGGCGGCGGCAATGGCGAATCGCCGGCG
AACGGCGAGGAACAGTCGAA

Downstream 100 bases:

>100_bases
GCGCGAGAGGCGAAGGCGGGATGCGCAACAGTCCCGTTTCGCCCGGCCCGGGCTACGCGCCGTCGCGCGGCGCGGCGCGC
ACGCGCAAACGCGGCGTCGC

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSAAVEPLVRDRYAVIGNPVAHSKSPFIHARFAEQTGEAIEYTHLLAPLDGFAATVREFTAQGGRGVNVTVPFKLEAYAL
ADTLSPRAAAAGAVNTLRFDADGIFGDNTDGVGLVRDIETNLGVSLTGARILLLGAGGAARGVVLPMLERGPASLTIVNR
TASKAEELVGQFTQAAHDAGCVLAGGGPERVAREPYDVIVNATAGSLDAALPECDAAAFCPATLAYDMMYGARPTVFMEH
AATLGARTADGLGMLVEQAAESFYLWRGVRPDGAPVLAALRAALAASAAH

Sequences:

>Translated_290_residues
MSAAVEPLVRDRYAVIGNPVAHSKSPFIHARFAEQTGEAIEYTHLLAPLDGFAATVREFTAQGGRGVNVTVPFKLEAYAL
ADTLSPRAAAAGAVNTLRFDADGIFGDNTDGVGLVRDIETNLGVSLTGARILLLGAGGAARGVVLPMLERGPASLTIVNR
TASKAEELVGQFTQAAHDAGCVLAGGGPERVAREPYDVIVNATAGSLDAALPECDAAAFCPATLAYDMMYGARPTVFMEH
AATLGARTADGLGMLVEQAAESFYLWRGVRPDGAPVLAALRAALAASAAH
>Mature_289_residues
SAAVEPLVRDRYAVIGNPVAHSKSPFIHARFAEQTGEAIEYTHLLAPLDGFAATVREFTAQGGRGVNVTVPFKLEAYALA
DTLSPRAAAAGAVNTLRFDADGIFGDNTDGVGLVRDIETNLGVSLTGARILLLGAGGAARGVVLPMLERGPASLTIVNRT
ASKAEELVGQFTQAAHDAGCVLAGGGPERVAREPYDVIVNATAGSLDAALPECDAAAFCPATLAYDMMYGARPTVFMEHA
ATLGARTADGLGMLVEQAAESFYLWRGVRPDGAPVLAALRAALAASAAH

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=278, Percent_Identity=49.2805755395683, Blast_Score=231, Evalue=4e-62,
Organism=Escherichia coli, GI1787983, Length=268, Percent_Identity=29.1044776119403, Blast_Score=102, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6320332, Length=165, Percent_Identity=33.9393939393939, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29945; Mature: 29814

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAVEPLVRDRYAVIGNPVAHSKSPFIHARFAEQTGEAIEYTHLLAPLDGFAATVREFT
CCCCHHHHHHCCHHHCCCCCCCCCCCEEEEEEHHHCCCHHHHHHHHHCHHHHHHHHHHHH
AQGGRGVNVTVPFKLEAYALADTLSPRAAAAGAVNTLRFDADGIFGDNTDGVGLVRDIET
HCCCCCEEEEECCEEEEEEHHHCCCCHHHHCCCCEEEEECCCCCCCCCCCCCEEEEECCC
NLGVSLTGARILLLGAGGAARGVVLPMLERGPASLTIVNRTASKAEELVGQFTQAAHDAG
CCCEEECCCEEEEEECCCCCCCEEEHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCC
CVLAGGGPERVAREPYDVIVNATAGSLDAALPECDAAAFCPATLAYDMMYGARPTVFMEH
EEEECCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHCHHHHHHHHHHCCCCHHHHHH
AATLGARTADGLGMLVEQAAESFYLWRGVRPDGAPVLAALRAALAASAAH
HHHHCCCCCCHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAAVEPLVRDRYAVIGNPVAHSKSPFIHARFAEQTGEAIEYTHLLAPLDGFAATVREFT
CCCHHHHHHCCHHHCCCCCCCCCCCEEEEEEHHHCCCHHHHHHHHHCHHHHHHHHHHHH
AQGGRGVNVTVPFKLEAYALADTLSPRAAAAGAVNTLRFDADGIFGDNTDGVGLVRDIET
HCCCCCEEEEECCEEEEEEHHHCCCCHHHHCCCCEEEEECCCCCCCCCCCCCEEEEECCC
NLGVSLTGARILLLGAGGAARGVVLPMLERGPASLTIVNRTASKAEELVGQFTQAAHDAG
CCCEEECCCEEEEEECCCCCCCEEEHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCC
CVLAGGGPERVAREPYDVIVNATAGSLDAALPECDAAAFCPATLAYDMMYGARPTVFMEH
EEEECCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHCHHHHHHHHHHCCCCHHHHHH
AATLGARTADGLGMLVEQAAESFYLWRGVRPDGAPVLAALRAALAASAAH
HHHHCCCCCCHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA