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The map label for this gene is atoC [H]

Identifier: 83719121

GI number: 83719121

Start: 1944269

End: 1945666

Strand: Reverse

Name: atoC [H]

Synonym: BTH_I1736

Alternate gene names: 83719121

Gene position: 1945666-1944269 (Counterclockwise)

Preceding gene: 83718614

Following gene: 83718620

Centisome position: 51.08

GC content: 69.74

Gene sequence:

>1398_bases
ATGCCACTCGCCCTGATTGTCGAAGACGATCCCAATAGCTTATCCGGCCTGACCGCGCTTCTTGCCGCGGACGGCTTCTC
GGTCGATACGGCGACATCGCTCGCCGAGGCGCGCGGCGCCCTCGCCCGGTCGATTCCCGACGTCGTCCTCGTCGACCTGA
ACCTGCCCGACGGCAGCGGCTTCGACCTGCTGCAGAACCTGCCGCAACAACAGCCGAACGGCTCGCTGCCGGTGATCGTG
CTGACCGGCAACGCGACCGTCGAGAGCGCGATCGAAGGGTTGCGGCACGGCGTCTGGGATTACCTGCTGAAGCCCGTCAA
CATCCCCCGGCTGCGCAGCCTGCTCGCGCGAATTCCCCGCCCGTACGAACTGATCGAGGAAGTGCAGGCGCTGCGCGCGT
CGCTGCGCCGACTCGGGCGCTTCGGTTCGCTCGTCGGGCGCAGCGACGCGATCCAGCACGTCTACGACATGATCGAGCAC
AACGCGCGCACCGAAACCGCGGTGCTGCTGTGGGGCGAGCCCGGCACCGGCAAGGAAGCGGCCGCGCGCACGCTGCACGA
GCTGAGCCGCCGCCGCAAGGGCCCGTTCGTCGCGTTCGATTGCCGCGCCGCCGTGCAATCGCCGCGCAACATCGAGACCA
ACGGCCGCGCGATCGAAAGCATGCTGCTCGGCCGCGAGCGCGGCGCGTACACGGGCGTCGAGCGGCGCGACCCCGGCCTC
TTCGAGCAGGCGAGCGGCGGCACGCTGTTCCTCGAGGAAATCACCGCGCTGCCGCTGCCGCTGCAGGAGGCGCTGTTGCG
CGCGCTCGATTCGCAGAACTTCATGCGCGTCGGCGGCACGACGGAAATCGCGAGCGACTTCCGGCTGATCGCGACGACGC
GCCGCCCCGCGCGCGAAGCGGTCGCGAACGGCACACTGCGCGAGGATCTTTGGCTGCGCCTCGACGCCGCATCGATCGGC
CTGCCGCCGCTGCGCGAGCGTGACGACGACGTCGTCGTCATGGCCGAGGCGTTCGTCGACGATCTGAACCGCGACGCGCG
CGCGGCGGGCCTGAACATCACCGACAAGCGAATCGCGCCCGCCTTCATCCGCGAATGCCTCGCATACGACTGGCCCGGCA
ACGTGCGCGAGTTGCGGGAGCGCGTGCGCATCGCATACGACCAGTCGGGCGATTTCATCGAAACGCTGCGCGCGGGCGAC
GCATATCCGCAGCCCGGCGCGGCGCTGAACGGCAGCAGCGTGCAGGTGCGCGTCGGCACGCCGCTCGCCGACGTCGAGGA
TCTGCTGATCCGCGCGACGCTCGACGCGGTCGGCGGCACGCGCCACCGCGCGGCGACGCTCCTCGGCATCAGCCCGAAGA
CGCTCTACAACAAGCTGCAGCGAATGAAGATCGGCTGA

Upstream 100 bases:

>100_bases
ACGCCAAGTGTGCGATGGGGCATAAAATTCATTTCTCATCCCGAAATGGGGGCTGTACGCCTGTCCTGCCGATGGACCGG
TCTTTCAACTCGCGCACACC

Downstream 100 bases:

>100_bases
CGCCCGGCCGACATCGAAGCGGGGCGGCCGCGCGCCGCCCTCGCCTGTTTCAAGTCAAGCGAACGTGCTGCGCAACAGTT
CCTGCGCGCTCAGATAGCGC

Product: sigma-54 dependent DNA-binding response regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MPLALIVEDDPNSLSGLTALLAADGFSVDTATSLAEARGALARSIPDVVLVDLNLPDGSGFDLLQNLPQQQPNGSLPVIV
LTGNATVESAIEGLRHGVWDYLLKPVNIPRLRSLLARIPRPYELIEEVQALRASLRRLGRFGSLVGRSDAIQHVYDMIEH
NARTETAVLLWGEPGTGKEAAARTLHELSRRRKGPFVAFDCRAAVQSPRNIETNGRAIESMLLGRERGAYTGVERRDPGL
FEQASGGTLFLEEITALPLPLQEALLRALDSQNFMRVGGTTEIASDFRLIATTRRPAREAVANGTLREDLWLRLDAASIG
LPPLRERDDDVVVMAEAFVDDLNRDARAAGLNITDKRIAPAFIRECLAYDWPGNVRELRERVRIAYDQSGDFIETLRAGD
AYPQPGAALNGSSVQVRVGTPLADVEDLLIRATLDAVGGTRHRAATLLGISPKTLYNKLQRMKIG

Sequences:

>Translated_465_residues
MPLALIVEDDPNSLSGLTALLAADGFSVDTATSLAEARGALARSIPDVVLVDLNLPDGSGFDLLQNLPQQQPNGSLPVIV
LTGNATVESAIEGLRHGVWDYLLKPVNIPRLRSLLARIPRPYELIEEVQALRASLRRLGRFGSLVGRSDAIQHVYDMIEH
NARTETAVLLWGEPGTGKEAAARTLHELSRRRKGPFVAFDCRAAVQSPRNIETNGRAIESMLLGRERGAYTGVERRDPGL
FEQASGGTLFLEEITALPLPLQEALLRALDSQNFMRVGGTTEIASDFRLIATTRRPAREAVANGTLREDLWLRLDAASIG
LPPLRERDDDVVVMAEAFVDDLNRDARAAGLNITDKRIAPAFIRECLAYDWPGNVRELRERVRIAYDQSGDFIETLRAGD
AYPQPGAALNGSSVQVRVGTPLADVEDLLIRATLDAVGGTRHRAATLLGISPKTLYNKLQRMKIG
>Mature_464_residues
PLALIVEDDPNSLSGLTALLAADGFSVDTATSLAEARGALARSIPDVVLVDLNLPDGSGFDLLQNLPQQQPNGSLPVIVL
TGNATVESAIEGLRHGVWDYLLKPVNIPRLRSLLARIPRPYELIEEVQALRASLRRLGRFGSLVGRSDAIQHVYDMIEHN
ARTETAVLLWGEPGTGKEAAARTLHELSRRRKGPFVAFDCRAAVQSPRNIETNGRAIESMLLGRERGAYTGVERRDPGLF
EQASGGTLFLEEITALPLPLQEALLRALDSQNFMRVGGTTEIASDFRLIATTRRPAREAVANGTLREDLWLRLDAASIGL
PPLRERDDDVVVMAEAFVDDLNRDARAAGLNITDKRIAPAFIRECLAYDWPGNVRELRERVRIAYDQSGDFIETLRAGDA
YPQPGAALNGSSVQVRVGTPLADVEDLLIRATLDAVGGTRHRAATLLGISPKTLYNKLQRMKIG

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=467, Percent_Identity=34.6895074946467, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1790437, Length=462, Percent_Identity=35.4978354978355, Blast_Score=238, Evalue=6e-64,
Organism=Escherichia coli, GI1790299, Length=482, Percent_Identity=33.6099585062241, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1788905, Length=380, Percent_Identity=33.9473684210526, Blast_Score=182, Evalue=6e-47,
Organism=Escherichia coli, GI87082117, Length=343, Percent_Identity=35.8600583090379, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1789087, Length=343, Percent_Identity=35.5685131195335, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1786524, Length=341, Percent_Identity=36.0703812316716, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI87081872, Length=244, Percent_Identity=38.9344262295082, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1789233, Length=338, Percent_Identity=32.5443786982249, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI87082152, Length=266, Percent_Identity=36.0902255639098, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1787583, Length=254, Percent_Identity=33.0708661417323, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789828, Length=277, Percent_Identity=33.5740072202166, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI87081858, Length=305, Percent_Identity=28.1967213114754, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786838, Length=132, Percent_Identity=34.0909090909091, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790552, Length=117, Percent_Identity=36.7521367521368, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786599, Length=132, Percent_Identity=30.3030303030303, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786784, Length=117, Percent_Identity=34.1880341880342, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50737; Mature: 50605

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLALIVEDDPNSLSGLTALLAADGFSVDTATSLAEARGALARSIPDVVLVDLNLPDGSG
CCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
FDLLQNLPQQQPNGSLPVIVLTGNATVESAIEGLRHGVWDYLLKPVNIPRLRSLLARIPR
HHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PYELIEEVQALRASLRRLGRFGSLVGRSDAIQHVYDMIEHNARTETAVLLWGEPGTGKEA
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHH
AARTLHELSRRRKGPFVAFDCRAAVQSPRNIETNGRAIESMLLGRERGAYTGVERRDPGL
HHHHHHHHHHHCCCCEEEEECHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
FEQASGGTLFLEEITALPLPLQEALLRALDSQNFMRVGGTTEIASDFRLIATTRRPAREA
CCCCCCCEEEHHHHHCCCCCHHHHHHHHHCCCCEEEECCCHHHHHCCEEEEECCCHHHHH
VANGTLREDLWLRLDAASIGLPPLRERDDDVVVMAEAFVDDLNRDARAAGLNITDKRIAP
HHCCCHHHHHEEEEEHHHCCCCCCCCCCCCEEEEHHHHHHHHCCCHHHCCCCCCHHHCCH
AFIRECLAYDWPGNVRELRERVRIAYDQSGDFIETLRAGDAYPQPGAALNGSSVQVRVGT
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEECC
PLADVEDLLIRATLDAVGGTRHRAATLLGISPKTLYNKLQRMKIG
CHHHHHHHHHHHHHHHHCCCHHHHEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PLALIVEDDPNSLSGLTALLAADGFSVDTATSLAEARGALARSIPDVVLVDLNLPDGSG
CEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
FDLLQNLPQQQPNGSLPVIVLTGNATVESAIEGLRHGVWDYLLKPVNIPRLRSLLARIPR
HHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PYELIEEVQALRASLRRLGRFGSLVGRSDAIQHVYDMIEHNARTETAVLLWGEPGTGKEA
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHH
AARTLHELSRRRKGPFVAFDCRAAVQSPRNIETNGRAIESMLLGRERGAYTGVERRDPGL
HHHHHHHHHHHCCCCEEEEECHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
FEQASGGTLFLEEITALPLPLQEALLRALDSQNFMRVGGTTEIASDFRLIATTRRPAREA
CCCCCCCEEEHHHHHCCCCCHHHHHHHHHCCCCEEEECCCHHHHHCCEEEEECCCHHHHH
VANGTLREDLWLRLDAASIGLPPLRERDDDVVVMAEAFVDDLNRDARAAGLNITDKRIAP
HHCCCHHHHHEEEEEHHHCCCCCCCCCCCCEEEEHHHHHHHHCCCHHHCCCCCCHHHCCH
AFIRECLAYDWPGNVRELRERVRIAYDQSGDFIETLRAGDAYPQPGAALNGSSVQVRVGT
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEECC
PLADVEDLLIRATLDAVGGTRHRAATLLGISPKTLYNKLQRMKIG
CHHHHHHHHHHHHHHHHCCCHHHHEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]