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The map label for this gene is prlC [H]

Identifier: 83718681

GI number: 83718681

Start: 2099203

End: 2101305

Strand: Reverse

Name: prlC [H]

Synonym: BTH_I1860

Alternate gene names: 83718681

Gene position: 2101305-2099203 (Counterclockwise)

Preceding gene: 83720145

Following gene: 83720627

Centisome position: 55.16

GC content: 67.76

Gene sequence:

>2103_bases
ATGTCCGTCAGCGCAAACGCCAATCCGCTTCTCGATTTCTCAGGTCTGCCTCGCTTCGGCGAAATTCGCCCCGAGCACGT
GACGCCCGCGCTCGACACGCTGCTCGCGAGCGCAAACGAAGCCGTCGAGCAAGCCGCGCGGCCCGACACGCCCGCGACCT
GGGCCGATGTCGTCGAGACCATCGAGCATGCGACCGAGCCGCTCGGCCGCGCATGGGGCGTCGTCGGCCACCTGAACGCG
GTCGCCGACACGCCCGAGCTGCGCGCCGTCTACGGCGAGAACCTGCCGCGCGTGACCGAGTTCTGGTCGAGCGTCGGCCA
GAATCTCGCGCTCTACGAGAAATACAAGGCGATCGCCGCGAGCGCGGAATACGCGACGCTGTCCGCCGAGCGCAAGAAGA
TCCTCGACAACGCGCTGCGCGACTTCCGCCTGTCGGGCGCGGAGCTGCCCGAGGACCGGAAGCCGCGCTTCGCCGAGCTG
CAGGAGCAGCAGGCGGCGCTGTCGAAATCGTTCTCCGATCACGTGCTCGACGCGACGAACGGCTACGCGTACTACGCGCA
GAGCGACGACGAACTGGCCGGCCTGCCCGACGATGCGATCGCGGCCGCCCGCGAGGCCGCGCAGAAGGAAGACAAGACCG
GCTGGAAGTTCACGCTGCACTTCCCGTCGTATTTCCCGGTGCTGCAATACGCGCAGAACCGCGCGATGCGCGAGGCGATG
TACCGCGCCTACGTGACGCGCGCGTCCGAGCTCGGCCCGCAGTACGGCAACGGCAAGGCAGACTGGGACAACACGACGAT
CGTCGCCGATCAACTCGCGCTGCGCCGCGAAGAGGCGACGATGCTCGGCTATCACGACTTCGCCGAGGTGTCGCTCGCGC
CGAAGATGGCGGAATCGCCGCAGCAGGTAATCGCGTTCCTCGAGGATCTCGCGAAGCGCGCGCGCCCGTTCGCCGAGAAG
GACTGGGACGAGCTGCGCGCGTTCGCGTCGAGCGAGCTCGGCCTCGCCGCGCTCGAGCCGTGGGACGTCGCGTATGCGGC
CGAGAAGCTGCGCGAGCGGCGCTACGCGTTCTCCGAGAACGAGGTGAAGCAGTACTTCCCCGAACCCGCGGTGCTCAAGG
GCCTGTTCACGGTCGCCGAGACGCTGTTCGGCGTGCGCATCGCGCGCGACGAAGCGCCCGTCTGGCACGAGGACGTGCGC
TTCTTCCGCGTCGAGAATCGCGACGGCTCGCTCGTCGCGCAGTTCTATCTCGACCTGTACGCGCGCGAAGGCAAGCGCGG
CGGCGCGTGGATGGACGACGCGCGCTCGCGCGCGAAGCGCGGCGACGGCAGCGTGCAGACGCCCGTCGCATACCTGACCT
GCAACTTCTCCGCGCCGATCGGCGGCAAACCCGCGTGCTTCACGCACGACGAAGTGATCACGCTGTTCCACGAGTTCGGC
CACGGGCTGCATCACATGCTCACGCGTGTCGACGAGATCGGCGTGTCGGGCATCAACGGCGTCGAATGGGACGCGGTCGA
GCTGCCGTCGCAGTTCATGGAGAACTTCTGCTGGGAATGGGACGTGCTCTCGTCGATGTCGTCGCACGTCGATACCGCGC
AGCCGCTGCCGCGCGCGCTGTTCGACAAGATGCTCGCCGCGAAGAACTTCCAGAGCGGCCTCGGCACGCTGCGCCAGATC
GTGTTCTCGATGTTCGACATGCTGCTGCACGTCGACTTCGATCCCGCGTCGGACAAGACAAGCGTCAACGACTTCGCGCG
CGAGATCAACGAGCGCTTCCACGTGATTCCGCAAGCGCCGTTCTCGCGCTGGCCGAACACGTTCAGCCACATCTTCGCGG
GCGGCTATGCGGCCGGCTACTACAGCTACAAGTGGGCCGAAGTGCTGTCCGCCGACGCATACGCGGCGTTCGAGGAAGCG
GCCGGCTCGGCGGGCAGCGTGCTCGACGCGACGACGGGCGCGCGCTATCGGCGCGAGATCCTCGAAGTCGGCGGCAGCCG
CCCGGCGATGGACTCGTTCAAGGCGTTCCGGGGCCGCGAGCCGAACATCGACGCATTGCTGCGTCACAGCGGGATGGCCG
ACGCCGAGCAGGCGCGCGCGTAA

Upstream 100 bases:

>100_bases
TTGGAAAGCGCGCGATGCGCCCCAATAATGTCGACATGACGCGACGGCCGGCGCCGTGCGCCGCCGTCTTTCGCCCAACC
CGAAACCGCCAGGGAGCTCT

Downstream 100 bases:

>100_bases
TGCGGCCGGCTTCGCGCGCGTAGATCGGGCGATCGCCCCGGCAATCGGCTCGGGGCGCGACAGGCCGCGTGCGCGCGCCG
CGCCCCGTCACATCGGCAGA

Product: oligopeptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 700; Mature: 699

Protein sequence:

>700_residues
MSVSANANPLLDFSGLPRFGEIRPEHVTPALDTLLASANEAVEQAARPDTPATWADVVETIEHATEPLGRAWGVVGHLNA
VADTPELRAVYGENLPRVTEFWSSVGQNLALYEKYKAIAASAEYATLSAERKKILDNALRDFRLSGAELPEDRKPRFAEL
QEQQAALSKSFSDHVLDATNGYAYYAQSDDELAGLPDDAIAAAREAAQKEDKTGWKFTLHFPSYFPVLQYAQNRAMREAM
YRAYVTRASELGPQYGNGKADWDNTTIVADQLALRREEATMLGYHDFAEVSLAPKMAESPQQVIAFLEDLAKRARPFAEK
DWDELRAFASSELGLAALEPWDVAYAAEKLRERRYAFSENEVKQYFPEPAVLKGLFTVAETLFGVRIARDEAPVWHEDVR
FFRVENRDGSLVAQFYLDLYAREGKRGGAWMDDARSRAKRGDGSVQTPVAYLTCNFSAPIGGKPACFTHDEVITLFHEFG
HGLHHMLTRVDEIGVSGINGVEWDAVELPSQFMENFCWEWDVLSSMSSHVDTAQPLPRALFDKMLAAKNFQSGLGTLRQI
VFSMFDMLLHVDFDPASDKTSVNDFAREINERFHVIPQAPFSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEA
AGSAGSVLDATTGARYRREILEVGGSRPAMDSFKAFRGREPNIDALLRHSGMADAEQARA

Sequences:

>Translated_700_residues
MSVSANANPLLDFSGLPRFGEIRPEHVTPALDTLLASANEAVEQAARPDTPATWADVVETIEHATEPLGRAWGVVGHLNA
VADTPELRAVYGENLPRVTEFWSSVGQNLALYEKYKAIAASAEYATLSAERKKILDNALRDFRLSGAELPEDRKPRFAEL
QEQQAALSKSFSDHVLDATNGYAYYAQSDDELAGLPDDAIAAAREAAQKEDKTGWKFTLHFPSYFPVLQYAQNRAMREAM
YRAYVTRASELGPQYGNGKADWDNTTIVADQLALRREEATMLGYHDFAEVSLAPKMAESPQQVIAFLEDLAKRARPFAEK
DWDELRAFASSELGLAALEPWDVAYAAEKLRERRYAFSENEVKQYFPEPAVLKGLFTVAETLFGVRIARDEAPVWHEDVR
FFRVENRDGSLVAQFYLDLYAREGKRGGAWMDDARSRAKRGDGSVQTPVAYLTCNFSAPIGGKPACFTHDEVITLFHEFG
HGLHHMLTRVDEIGVSGINGVEWDAVELPSQFMENFCWEWDVLSSMSSHVDTAQPLPRALFDKMLAAKNFQSGLGTLRQI
VFSMFDMLLHVDFDPASDKTSVNDFAREINERFHVIPQAPFSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEA
AGSAGSVLDATTGARYRREILEVGGSRPAMDSFKAFRGREPNIDALLRHSGMADAEQARA
>Mature_699_residues
SVSANANPLLDFSGLPRFGEIRPEHVTPALDTLLASANEAVEQAARPDTPATWADVVETIEHATEPLGRAWGVVGHLNAV
ADTPELRAVYGENLPRVTEFWSSVGQNLALYEKYKAIAASAEYATLSAERKKILDNALRDFRLSGAELPEDRKPRFAELQ
EQQAALSKSFSDHVLDATNGYAYYAQSDDELAGLPDDAIAAAREAAQKEDKTGWKFTLHFPSYFPVLQYAQNRAMREAMY
RAYVTRASELGPQYGNGKADWDNTTIVADQLALRREEATMLGYHDFAEVSLAPKMAESPQQVIAFLEDLAKRARPFAEKD
WDELRAFASSELGLAALEPWDVAYAAEKLRERRYAFSENEVKQYFPEPAVLKGLFTVAETLFGVRIARDEAPVWHEDVRF
FRVENRDGSLVAQFYLDLYAREGKRGGAWMDDARSRAKRGDGSVQTPVAYLTCNFSAPIGGKPACFTHDEVITLFHEFGH
GLHHMLTRVDEIGVSGINGVEWDAVELPSQFMENFCWEWDVLSSMSSHVDTAQPLPRALFDKMLAAKNFQSGLGTLRQIV
FSMFDMLLHVDFDPASDKTSVNDFAREINERFHVIPQAPFSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAA
GSAGSVLDATTGARYRREILEVGGSRPAMDSFKAFRGREPNIDALLRHSGMADAEQARA

Specific function: May play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. Can cleave N-acetyl-L-Ala(4) [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=622, Percent_Identity=31.9935691318328, Blast_Score=311, Evalue=2e-84,
Organism=Homo sapiens, GI14149738, Length=623, Percent_Identity=31.7817014446228, Blast_Score=291, Evalue=1e-78,
Organism=Homo sapiens, GI156105687, Length=670, Percent_Identity=24.9253731343284, Blast_Score=177, Evalue=4e-44,
Organism=Escherichia coli, GI1789913, Length=687, Percent_Identity=49.7816593886463, Blast_Score=685, Evalue=0.0,
Organism=Escherichia coli, GI1787819, Length=695, Percent_Identity=30.0719424460432, Blast_Score=266, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71999758, Length=488, Percent_Identity=26.2295081967213, Blast_Score=129, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI32565901, Length=630, Percent_Identity=20.952380952381, Blast_Score=95, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319793, Length=691, Percent_Identity=27.7858176555716, Blast_Score=280, Evalue=4e-76,
Organism=Saccharomyces cerevisiae, GI6322715, Length=614, Percent_Identity=24.5928338762215, Blast_Score=137, Evalue=5e-33,
Organism=Drosophila melanogaster, GI21356111, Length=697, Percent_Identity=26.9727403156385, Blast_Score=238, Evalue=1e-62,
Organism=Drosophila melanogaster, GI20129717, Length=557, Percent_Identity=25.673249551167, Blast_Score=164, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.24.70 [H]

Molecular weight: Translated: 77965; Mature: 77833

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSANANPLLDFSGLPRFGEIRPEHVTPALDTLLASANEAVEQAARPDTPATWADVVET
CCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
IEHATEPLGRAWGVVGHLNAVADTPELRAVYGENLPRVTEFWSSVGQNLALYEKYKAIAA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
SAEYATLSAERKKILDNALRDFRLSGAELPEDRKPRFAELQEQQAALSKSFSDHVLDATN
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
GYAYYAQSDDELAGLPDDAIAAAREAAQKEDKTGWKFTLHFPSYFPVLQYAQNRAMREAM
CEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
YRAYVTRASELGPQYGNGKADWDNTTIVADQLALRREEATMLGYHDFAEVSLAPKMAESP
HHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHCCH
QQVIAFLEDLAKRARPFAEKDWDELRAFASSELGLAALEPWDVAYAAEKLRERRYAFSEN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHCCCHH
EVKQYFPEPAVLKGLFTVAETLFGVRIARDEAPVWHEDVRFFRVENRDGSLVAQFYLDLY
HHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCHHCCEEEEEECCCCHHHHHHHHHHH
AREGKRGGAWMDDARSRAKRGDGSVQTPVAYLTCNFSAPIGGKPACFTHDEVITLFHEFG
HHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCEECHHHHHHHHHHHH
HGLHHMLTRVDEIGVSGINGVEWDAVELPSQFMENFCWEWDVLSSMSSHVDTAQPLPRAL
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHH
FDKMLAAKNFQSGLGTLRQIVFSMFDMLLHVDFDPASDKTSVNDFAREINERFHVIPQAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHEECCCCH
FSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAAGSAGSVLDATTGARYRREI
HHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHH
LEVGGSRPAMDSFKAFRGREPNIDALLRHSGMADAEQARA
HHCCCCCCCHHHHHHHCCCCCCHHHHHHHCCCCCHHHCCC
>Mature Secondary Structure 
SVSANANPLLDFSGLPRFGEIRPEHVTPALDTLLASANEAVEQAARPDTPATWADVVET
CCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
IEHATEPLGRAWGVVGHLNAVADTPELRAVYGENLPRVTEFWSSVGQNLALYEKYKAIAA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
SAEYATLSAERKKILDNALRDFRLSGAELPEDRKPRFAELQEQQAALSKSFSDHVLDATN
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
GYAYYAQSDDELAGLPDDAIAAAREAAQKEDKTGWKFTLHFPSYFPVLQYAQNRAMREAM
CEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
YRAYVTRASELGPQYGNGKADWDNTTIVADQLALRREEATMLGYHDFAEVSLAPKMAESP
HHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHCCH
QQVIAFLEDLAKRARPFAEKDWDELRAFASSELGLAALEPWDVAYAAEKLRERRYAFSEN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHCCCHH
EVKQYFPEPAVLKGLFTVAETLFGVRIARDEAPVWHEDVRFFRVENRDGSLVAQFYLDLY
HHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCHHCCEEEEEECCCCHHHHHHHHHHH
AREGKRGGAWMDDARSRAKRGDGSVQTPVAYLTCNFSAPIGGKPACFTHDEVITLFHEFG
HHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCEECHHHHHHHHHHHH
HGLHHMLTRVDEIGVSGINGVEWDAVELPSQFMENFCWEWDVLSSMSSHVDTAQPLPRAL
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHH
FDKMLAAKNFQSGLGTLRQIVFSMFDMLLHVDFDPASDKTSVNDFAREINERFHVIPQAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHEECCCCH
FSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAAGSAGSVLDATTGARYRREI
HHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHH
LEVGGSRPAMDSFKAFRGREPNIDALLRHSGMADAEQARA
HHCCCCCCCHHHHHHHCCCCCCHHHHHHHCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]