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The map label for this gene is gph [C]

Identifier: 83718563

GI number: 83718563

Start: 1920416

End: 1921084

Strand: Direct

Name: gph [C]

Synonym: BTH_I1709

Alternate gene names: 83718563

Gene position: 1920416-1921084 (Clockwise)

Preceding gene: 83719283

Following gene: 83719236

Centisome position: 50.42

GC content: 69.36

Gene sequence:

>669_bases
ATGACACGCATGGCACGACAGCAATTTGATCTGATCGTCTTCGACTGGGACGGCACGCTGATGGATTCGACCGCGCACAT
CGCGCAGTGCATCCAGGCCGCGTGCCGGGATCTCGGCGTGCCCGCGCCGTCCGACGAGGCGGCCCGCTACGTGATCGGGC
TCGGCCTGCGCGACGCGCTCGCCGTGACCGCGCCGAGCGTCGATCCCGCCGACTATCCGCGGCTCGCCGAGCGCTACCGG
TTCCACTATCTGATCAAGGACCAGCGAACCGAGCTCTTCGGCGGCGTGCGCGAAATGCTGGAAGAACTGCGCGACACGGG
CTACCTGCTCGCCGTCGCGACGGGCAAGGGGCGCGTCGGGTTGAATCGCGCGCTCGATCAGGCGAAGCTCACGAGCCTCT
TCGACGCCACGCGCTGCGCGGACGAGACGTTCTCGAAGCCGCATCCGGCGATGCTGCAGGAATTGTCGCGCGAACTGGGG
CAGGATCTGGCGCGCACCGTGATGATCGGCGACACGACGCACGACCTGCAGATGGCGGCGAGCGCCGGCGCGGCGGGCAT
CGGCGTCGCGTACGGCGCGCATTCGGCTGACGCGCTCGCGGCGCTGTCGCCGCGCTTCGTCGCGCCCGACGTCGCATCGC
TCGCCAGTTGGCTGCGGGAGCACGCATGA

Upstream 100 bases:

>100_bases
TCGCGCATCCGCTGACGGGCGAGCCGCTGCAGTTCGACGCGCCGCTGCCCGCCGAGTGCCGGCAATTCCTCGATCAACTC
ACCGACTTGCGCGATACCGC

Downstream 100 bases:

>100_bases
CGGGCGGAGACGACGCGCGCTTCGTGTGCGCGGCCGATGCGCTCGTCGACGGCGGCGCGGGCGTGCGGCTCGACGCGACG
CTGCGCGGCGAGCCCGCCGT

Product: haloacid dehalogenase-like hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTRMARQQFDLIVFDWDGTLMDSTAHIAQCIQAACRDLGVPAPSDEAARYVIGLGLRDALAVTAPSVDPADYPRLAERYR
FHYLIKDQRTELFGGVREMLEELRDTGYLLAVATGKGRVGLNRALDQAKLTSLFDATRCADETFSKPHPAMLQELSRELG
QDLARTVMIGDTTHDLQMAASAGAAGIGVAYGAHSADALAALSPRFVAPDVASLASWLREHA

Sequences:

>Translated_222_residues
MTRMARQQFDLIVFDWDGTLMDSTAHIAQCIQAACRDLGVPAPSDEAARYVIGLGLRDALAVTAPSVDPADYPRLAERYR
FHYLIKDQRTELFGGVREMLEELRDTGYLLAVATGKGRVGLNRALDQAKLTSLFDATRCADETFSKPHPAMLQELSRELG
QDLARTVMIGDTTHDLQMAASAGAAGIGVAYGAHSADALAALSPRFVAPDVASLASWLREHA
>Mature_221_residues
TRMARQQFDLIVFDWDGTLMDSTAHIAQCIQAACRDLGVPAPSDEAARYVIGLGLRDALAVTAPSVDPADYPRLAERYRF
HYLIKDQRTELFGGVREMLEELRDTGYLLAVATGKGRVGLNRALDQAKLTSLFDATRCADETFSKPHPAMLQELSRELGQ
DLARTVMIGDTTHDLQMAASAGAAGIGVAYGAHSADALAALSPRFVAPDVASLASWLREHA

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR000150
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 24062; Mature: 23930

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRMARQQFDLIVFDWDGTLMDSTAHIAQCIQAACRDLGVPAPSDEAARYVIGLGLRDAL
CCCCHHHHCCEEEECCCCCHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHH
AVTAPSVDPADYPRLAERYRFHYLIKDQRTELFGGVREMLEELRDTGYLLAVATGKGRVG
HEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCC
LNRALDQAKLTSLFDATRCADETFSKPHPAMLQELSRELGQDLARTVMIGDTTHDLQMAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SAGAAGIGVAYGAHSADALAALSPRFVAPDVASLASWLREHA
HCCCCCHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TRMARQQFDLIVFDWDGTLMDSTAHIAQCIQAACRDLGVPAPSDEAARYVIGLGLRDAL
CCCHHHHCCEEEECCCCCHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHH
AVTAPSVDPADYPRLAERYRFHYLIKDQRTELFGGVREMLEELRDTGYLLAVATGKGRVG
HEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCC
LNRALDQAKLTSLFDATRCADETFSKPHPAMLQELSRELGQDLARTVMIGDTTHDLQMAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SAGAAGIGVAYGAHSADALAALSPRFVAPDVASLASWLREHA
HCCCCCHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA