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The map label for this gene is 83593948

Identifier: 83593948

GI number: 83593948

Start: 3044654

End: 3045583

Strand: Direct

Name: 83593948

Synonym: Rru_A2616

Alternate gene names: NA

Gene position: 3044654-3045583 (Clockwise)

Preceding gene: 83593943

Following gene: 83593949

Centisome position: 69.95

GC content: 64.52

Gene sequence:

>930_bases
ATGACGACATTGTTGGTCTCTCATCATGCCTGTGTCGAACACGATCCCGGGGCCTTCCATCCGGAATGTCCCGACCGGTT
GCGCGCCGTTCAGCGGGTCCTTGAAGCCGAGGACTTCATGCTGCTGTTGCGCGACGAAGCTCCCCATGTGACCCGCGAAC
AGCTGCTGCGGGTCCACCCCCTCTCGCATGTCGAATTTCTTCTCGATCACGTGCCGCGCGAGGGCACCTATCACATCGAC
GGCGATACGGTGATGTCGCCGGATTCGGGCGAGGCCGCCCTGCGCGCCGCCGGCGGCATGGTTCAGGCGGTGGACGCGGT
GATGGACAAATCGGTCCGCAACGCCTTCGTCGCCGTCCGTCCCCCCGGTCACCACGCCGAACTGGCCACGGCCATGGGCT
TCTGCCTGTTCAACAACGCCGCCATCGGCGCCTATCACGCCCGGGCGCGCTGGGGGGCCGAACGCGTCGCGGTGATCGAC
TGGGACGTTCACCACGGCAATGGCACCCAGCATATCTTCTGGGATGATCCGGCGATGTTCTATGCCTCGACCCACGAGGC
CCACAGCTTTCCCAATACCGGCTTCGTCGATGAAACCGGCGGTCACGGCAATATCGTCAATTGCCCCCTGCGCTCGGGCG
CCGACGGCCTGCGCTTTCGCGAGGCCTTCACCGAGCGGATCACCCCGGCGCTGCGCGCCTTCGCCCCCGATCTGATCATC
ATTTCCGCCGGCTTCGACGCCCATGTGATGGACCCGATGGCCAATCTCAACCTCAAGGTCGCCGATTTCGTCTGGGCGAC
CGAGCAGGTCCTCGATGTCGCCAATGACGTCTGCGACAGCCGGGTGGTGTCGGTGCTCGAAGGCGGTTACGATCTGACGG
CCCTGGCCTCTTGCGTCTCGGCTCACGTCAAGACCTTGATGGAACGCTGA

Upstream 100 bases:

>100_bases
CAACCAAGTTTTGGAAAGCCCCTTGCGTACATCAGCACTGCCTGAAATATAGGAATCGAAGGGCTGCAAAAAACTCATAA
CGACGCCCGGGGAGGAAGAC

Downstream 100 bases:

>100_bases
CCCCGCCCGAAAACCGCCGGGCTTTGGCGTAAACGCGGTTTCGGTGGGCGGTGTGCGCGGGGCGGTTGCTCCGCGCCCCG
CCTGTCGTTACAATCCCGCG

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTTLLVSHHACVEHDPGAFHPECPDRLRAVQRVLEAEDFMLLLRDEAPHVTREQLLRVHPLSHVEFLLDHVPREGTYHID
GDTVMSPDSGEAALRAAGGMVQAVDAVMDKSVRNAFVAVRPPGHHAELATAMGFCLFNNAAIGAYHARARWGAERVAVID
WDVHHGNGTQHIFWDDPAMFYASTHEAHSFPNTGFVDETGGHGNIVNCPLRSGADGLRFREAFTERITPALRAFAPDLII
ISAGFDAHVMDPMANLNLKVADFVWATEQVLDVANDVCDSRVVSVLEGGYDLTALASCVSAHVKTLMER

Sequences:

>Translated_309_residues
MTTLLVSHHACVEHDPGAFHPECPDRLRAVQRVLEAEDFMLLLRDEAPHVTREQLLRVHPLSHVEFLLDHVPREGTYHID
GDTVMSPDSGEAALRAAGGMVQAVDAVMDKSVRNAFVAVRPPGHHAELATAMGFCLFNNAAIGAYHARARWGAERVAVID
WDVHHGNGTQHIFWDDPAMFYASTHEAHSFPNTGFVDETGGHGNIVNCPLRSGADGLRFREAFTERITPALRAFAPDLII
ISAGFDAHVMDPMANLNLKVADFVWATEQVLDVANDVCDSRVVSVLEGGYDLTALASCVSAHVKTLMER
>Mature_308_residues
TTLLVSHHACVEHDPGAFHPECPDRLRAVQRVLEAEDFMLLLRDEAPHVTREQLLRVHPLSHVEFLLDHVPREGTYHIDG
DTVMSPDSGEAALRAAGGMVQAVDAVMDKSVRNAFVAVRPPGHHAELATAMGFCLFNNAAIGAYHARARWGAERVAVIDW
DVHHGNGTQHIFWDDPAMFYASTHEAHSFPNTGFVDETGGHGNIVNCPLRSGADGLRFREAFTERITPALRAFAPDLIII
SAGFDAHVMDPMANLNLKVADFVWATEQVLDVANDVCDSRVVSVLEGGYDLTALASCVSAHVKTLMER

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128864, Length=305, Percent_Identity=33.4426229508197, Blast_Score=164, Evalue=7e-41,
Organism=Homo sapiens, GI20070354, Length=310, Percent_Identity=36.4516129032258, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI17158039, Length=247, Percent_Identity=38.0566801619433, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI30795204, Length=247, Percent_Identity=38.0566801619433, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI30795202, Length=247, Percent_Identity=38.0566801619433, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI169234807, Length=246, Percent_Identity=38.2113821138211, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI148539870, Length=246, Percent_Identity=38.2113821138211, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI153085395, Length=247, Percent_Identity=38.4615384615385, Blast_Score=157, Evalue=8e-39,
Organism=Homo sapiens, GI62750349, Length=247, Percent_Identity=36.4372469635627, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI62750347, Length=247, Percent_Identity=36.4372469635627, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI226529806, Length=310, Percent_Identity=34.1935483870968, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI13128862, Length=314, Percent_Identity=25.1592356687898, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI8923769, Length=293, Percent_Identity=24.9146757679181, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI13128860, Length=302, Percent_Identity=23.841059602649, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI293336691, Length=265, Percent_Identity=24.9056603773585, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI262073088, Length=173, Percent_Identity=27.1676300578035, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540334, Length=309, Percent_Identity=35.2750809061489, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI17540332, Length=309, Percent_Identity=35.2750809061489, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI193206283, Length=309, Percent_Identity=35.2750809061489, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI193209491, Length=336, Percent_Identity=33.0357142857143, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI25154020, Length=294, Percent_Identity=27.891156462585, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI25154022, Length=294, Percent_Identity=28.2312925170068, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17537347, Length=296, Percent_Identity=30.4054054054054, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17534739, Length=304, Percent_Identity=25, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561978, Length=147, Percent_Identity=30.6122448979592, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508561, Length=139, Percent_Identity=29.4964028776978, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324307, Length=317, Percent_Identity=33.1230283911672, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6325141, Length=333, Percent_Identity=27.027027027027, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323999, Length=263, Percent_Identity=26.615969581749, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6321244, Length=263, Percent_Identity=26.2357414448669, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6325325, Length=192, Percent_Identity=23.9583333333333, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI281360899, Length=315, Percent_Identity=34.9206349206349, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24642146, Length=315, Percent_Identity=34.9206349206349, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24642142, Length=315, Percent_Identity=34.9206349206349, Blast_Score=171, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24642144, Length=315, Percent_Identity=34.9206349206349, Blast_Score=171, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24641720, Length=338, Percent_Identity=34.3195266272189, Blast_Score=150, Evalue=8e-37,
Organism=Drosophila melanogaster, GI281360799, Length=339, Percent_Identity=34.8082595870207, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281360801, Length=339, Percent_Identity=34.8082595870207, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24657891, Length=300, Percent_Identity=26, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24644244, Length=196, Percent_Identity=29.0816326530612, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33854; Mature: 33722

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLLVSHHACVEHDPGAFHPECPDRLRAVQRVLEAEDFMLLLRDEAPHVTREQLLRVHP
CCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHCC
LSHVEFLLDHVPREGTYHIDGDTVMSPDSGEAALRAAGGMVQAVDAVMDKSVRNAFVAVR
HHHHHHHHHHCCCCCEEEECCCEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHCCEEEEC
PPGHHAELATAMGFCLFNNAAIGAYHARARWGAERVAVIDWDVHHGNGTQHIFWDDPAMF
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEEEEECCCCCEEEEECCCEEE
YASTHEAHSFPNTGFVDETGGHGNIVNCPLRSGADGLRFREAFTERITPALRAFAPDLII
EEECCHHCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
ISAGFDAHVMDPMANLNLKVADFVWATEQVLDVANDVCDSRVVSVLEGGYDLTALASCVS
EECCCCCHHHCHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AHVKTLMER
HHHHHHHCC
>Mature Secondary Structure 
TTLLVSHHACVEHDPGAFHPECPDRLRAVQRVLEAEDFMLLLRDEAPHVTREQLLRVHP
CEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHCC
LSHVEFLLDHVPREGTYHIDGDTVMSPDSGEAALRAAGGMVQAVDAVMDKSVRNAFVAVR
HHHHHHHHHHCCCCCEEEECCCEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHCCEEEEC
PPGHHAELATAMGFCLFNNAAIGAYHARARWGAERVAVIDWDVHHGNGTQHIFWDDPAMF
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEEEEECCCCCEEEEECCCEEE
YASTHEAHSFPNTGFVDETGGHGNIVNCPLRSGADGLRFREAFTERITPALRAFAPDLII
EEECCHHCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
ISAGFDAHVMDPMANLNLKVADFVWATEQVLDVANDVCDSRVVSVLEGGYDLTALASCVS
EECCCCCHHHCHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AHVKTLMER
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]