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The map label for this gene is pbpG [H]

Identifier: 83593855

GI number: 83593855

Start: 2929751

End: 2932003

Strand: Direct

Name: pbpG [H]

Synonym: Rru_A2520

Alternate gene names: 83593855

Gene position: 2929751-2932003 (Clockwise)

Preceding gene: 83593853

Following gene: 83593856

Centisome position: 67.31

GC content: 70.84

Gene sequence:

>2253_bases
ATGATTCCCTCGCCTTCTGATCGCCTGTCGGGCAACCGCCGTCCCGAAGACATCGACCCGCCCGAAGCCCCCCGCCCCCC
TCGCCGACCGGCTTTGCGGCACCCGGGACGGATCGCCCTGGCGATCGCCGGCGTGGTTCTGGCGCTTGGCGTCCTTGTGC
TGGCGATCAACCTCTACACCATGCCGCTGTCGCCCAGCTTCCAGGAGCCCGAGCGTTCGGGGTTTCTGATCGCCGACGCG
GAAGGCACGGTGGTGGCGACGCGGGGGGTCACCGCCGGCCGGCCAGTCGCCCTGGCCGAGATGCCCGCTTCGCTGGTCAA
CGCGGTGATCGCCTTCGAAGACCGCCGCTTCCGCGACCATTGGGGCGTCGATCCGAGGGGCATCGCGCGGGCGATCTGGG
TCAATCTGCGCTCGGGCGGACGGACGCAAGGGGCCAGCACCCTGACCCAGCAACTGGTCAAGAACACCCTGCTCACCCCG
GAAAAGACCTTCACCCGCAAGATCCAGGAGGCCATGCTCGCCCTGTGGATCGAGCGCAAGCTGACCAAGGACGAGATTCT
AGAACGCTACCTCAATTCGCTGTATCTCGGCGCCGGCTCCTATGGCGTCGATGCCGCCGCCCGGCGTTATTTCAACAAGC
CGGTGACCGATCTGTCGCTGGCGGAATCGGCGATGATCGCCGGATTGATCCAGGCCCCGGCCCGCACCGGCCCGACCACG
GCCCTTGATGTCGCCCGCCAGCGCGCCGAACTGGTTCTGGACGTGATGCGCGACCAGGGACTGATCGGCGCCGACGAGGC
GACCTGGGCCAAGGCCCATCCCGCCTCGCTCGCCGTTCCGCCGGTCGAACTGCCGGCCTATGGCGCGGTGTCGGACTGGA
TCGCCGATGAGGCGCGCAAGGCCCTGGGGCCGCTGTCGGGCGACTTCCTGGTGGTCAGCACCCTTGATCGCCGGCTGCAG
GTGCTGGCCCAGCAGACGATCCAGGAGGGAATGGCCGCCGAGGGCGCAGGCCTGCGCGCCACCCAGGCCGCCCTGGTGGC
GATGGCCCCCGATGGCCGGGTCCTGGCCATGGTCGGCGGTCGCGACTATCAGGAAAGCCAGTTCAATCGCGCCGTCCAGG
CCCGCCGCCAGCCCGGTTCGATCTTCAAGCTGTTTGTCTATCTTACGGCGCTGTCGAACAACTGGCGCCCCGATGACCCG
ATCGACGACACGCCGCTGACGATCGACGGCTGGAGCCCCGAGAATTATGGCGGCGGTGCCGGCCATGGCAGCGTGCCGCT
GCGCGTCGCCTTCGCCCATTCCTACAATCTGGCCGCCGTCCGCCTGCAAGAGGCGGTGGGCCGCGAGGCGGTGATCGCCA
CGGCGCGATCGATGGGATTGAAGGACGATCTCCAACCTTTGCCCAGTCTGGCCCTTGGCACCTTCCCCGCCACCTTGCTT
GATCTGACCAGCGCCTTCGCCGCCGTCGCCGCCGACCGTGCCACCGTCCAGCCCCGGGTGATCGAGGTTCTGCGCACCCC
GGGCAGTGGCGAGATCCGCCCGCCGGTGCGCCAGTCGGGCCGGGCGCCCTGGCCGCGCGCCAGCGCCCTTGATCTGCTCA
ACGCCGTTGTCACCCAAGGGACCGGACGGGCCGCCGCCCTGGGGGTGCCGACCTACGGCAAGACCGGCACCACCCAGGAC
AACCGCGACGCCTGGTTCATCGGCTTCGCCGGCAATCTGGTGATCGGCGTCTGGGTCGGCAATGACGACGAAACGCCGAT
GACCGGCATCAGCGGCGGCGGCCTGCCGGCCAAGCTGTGGCAAAGCTTCGCCGCCCGCGCCCTGGCCGGCGGGGTCGCGG
GCAGCGCCCCGGCCGCGCCGATCGCCGCCGCCACCACCGCCACCCTCCCCGCCGCCGCTCCGCCCGCCCCCACCCCGGCG
CCGGCCGTCCCGTCGCGCCAACCGTTCTCGGCCGTGCCCGAGGCGGTGGTCGATACCGGAACCTTGCGCCTGGGCGGGCG
GGTGGTTCGCCTTGAAGGGGTGAAGGGCCTCACCGGCCGTCCGGCCCGCGATATGGCGGGCTATATCGGCGATCGCTCCG
TCACCTGCCGCCCGGCGGGACGCGAGCGCTGGCGCTGCGATGTCGAAGGCTGGGATCTGTCGGAAGTGGCCTTGTTCAAC
GGCGGCGCCCGCGCCACCGCCGACGCGCCGGCCGATCTGGTCGCCGCCGAACGCAAGGCCCGCCAAGCCGGCCGGGGTGT
CTGGGGGCGCTGA

Upstream 100 bases:

>100_bases
TGCCCTAGGACGGCCATGGTCTTTGACTTAGGCTTGACCGCCACCCAAGCCCGCCGTCTCCTCTTCCCGGCCCGAAAGCG
GCCACACGCAAGGCCCGCCC

Downstream 100 bases:

>100_bases
CCCCCGCCCCCCTCCCGCCGGCGGGTCCTTGGCGTCCACGATCACGCCCTTTTCCCGACATCGCGCTTTCCTGCCCCCTT
GGCCTGCGCTACATCATTGG

Product: penicillin-binding protein 1A

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 750; Mature: 750

Protein sequence:

>750_residues
MIPSPSDRLSGNRRPEDIDPPEAPRPPRRPALRHPGRIALAIAGVVLALGVLVLAINLYTMPLSPSFQEPERSGFLIADA
EGTVVATRGVTAGRPVALAEMPASLVNAVIAFEDRRFRDHWGVDPRGIARAIWVNLRSGGRTQGASTLTQQLVKNTLLTP
EKTFTRKIQEAMLALWIERKLTKDEILERYLNSLYLGAGSYGVDAAARRYFNKPVTDLSLAESAMIAGLIQAPARTGPTT
ALDVARQRAELVLDVMRDQGLIGADEATWAKAHPASLAVPPVELPAYGAVSDWIADEARKALGPLSGDFLVVSTLDRRLQ
VLAQQTIQEGMAAEGAGLRATQAALVAMAPDGRVLAMVGGRDYQESQFNRAVQARRQPGSIFKLFVYLTALSNNWRPDDP
IDDTPLTIDGWSPENYGGGAGHGSVPLRVAFAHSYNLAAVRLQEAVGREAVIATARSMGLKDDLQPLPSLALGTFPATLL
DLTSAFAAVAADRATVQPRVIEVLRTPGSGEIRPPVRQSGRAPWPRASALDLLNAVVTQGTGRAAALGVPTYGKTGTTQD
NRDAWFIGFAGNLVIGVWVGNDDETPMTGISGGGLPAKLWQSFAARALAGGVAGSAPAAPIAAATTATLPAAAPPAPTPA
PAVPSRQPFSAVPEAVVDTGTLRLGGRVVRLEGVKGLTGRPARDMAGYIGDRSVTCRPAGRERWRCDVEGWDLSEVALFN
GGARATADAPADLVAAERKARQAGRGVWGR

Sequences:

>Translated_750_residues
MIPSPSDRLSGNRRPEDIDPPEAPRPPRRPALRHPGRIALAIAGVVLALGVLVLAINLYTMPLSPSFQEPERSGFLIADA
EGTVVATRGVTAGRPVALAEMPASLVNAVIAFEDRRFRDHWGVDPRGIARAIWVNLRSGGRTQGASTLTQQLVKNTLLTP
EKTFTRKIQEAMLALWIERKLTKDEILERYLNSLYLGAGSYGVDAAARRYFNKPVTDLSLAESAMIAGLIQAPARTGPTT
ALDVARQRAELVLDVMRDQGLIGADEATWAKAHPASLAVPPVELPAYGAVSDWIADEARKALGPLSGDFLVVSTLDRRLQ
VLAQQTIQEGMAAEGAGLRATQAALVAMAPDGRVLAMVGGRDYQESQFNRAVQARRQPGSIFKLFVYLTALSNNWRPDDP
IDDTPLTIDGWSPENYGGGAGHGSVPLRVAFAHSYNLAAVRLQEAVGREAVIATARSMGLKDDLQPLPSLALGTFPATLL
DLTSAFAAVAADRATVQPRVIEVLRTPGSGEIRPPVRQSGRAPWPRASALDLLNAVVTQGTGRAAALGVPTYGKTGTTQD
NRDAWFIGFAGNLVIGVWVGNDDETPMTGISGGGLPAKLWQSFAARALAGGVAGSAPAAPIAAATTATLPAAAPPAPTPA
PAVPSRQPFSAVPEAVVDTGTLRLGGRVVRLEGVKGLTGRPARDMAGYIGDRSVTCRPAGRERWRCDVEGWDLSEVALFN
GGARATADAPADLVAAERKARQAGRGVWGR
>Mature_750_residues
MIPSPSDRLSGNRRPEDIDPPEAPRPPRRPALRHPGRIALAIAGVVLALGVLVLAINLYTMPLSPSFQEPERSGFLIADA
EGTVVATRGVTAGRPVALAEMPASLVNAVIAFEDRRFRDHWGVDPRGIARAIWVNLRSGGRTQGASTLTQQLVKNTLLTP
EKTFTRKIQEAMLALWIERKLTKDEILERYLNSLYLGAGSYGVDAAARRYFNKPVTDLSLAESAMIAGLIQAPARTGPTT
ALDVARQRAELVLDVMRDQGLIGADEATWAKAHPASLAVPPVELPAYGAVSDWIADEARKALGPLSGDFLVVSTLDRRLQ
VLAQQTIQEGMAAEGAGLRATQAALVAMAPDGRVLAMVGGRDYQESQFNRAVQARRQPGSIFKLFVYLTALSNNWRPDDP
IDDTPLTIDGWSPENYGGGAGHGSVPLRVAFAHSYNLAAVRLQEAVGREAVIATARSMGLKDDLQPLPSLALGTFPATLL
DLTSAFAAVAADRATVQPRVIEVLRTPGSGEIRPPVRQSGRAPWPRASALDLLNAVVTQGTGRAAALGVPTYGKTGTTQD
NRDAWFIGFAGNLVIGVWVGNDDETPMTGISGGGLPAKLWQSFAARALAGGVAGSAPAAPIAAATTATLPAAAPPAPTPA
PAVPSRQPFSAVPEAVVDTGTLRLGGRVVRLEGVKGLTGRPARDMAGYIGDRSVTCRPAGRERWRCDVEGWDLSEVALFN
GGARATADAPADLVAAERKARQAGRGVWGR

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=529, Percent_Identity=33.2703213610586, Blast_Score=209, Evalue=5e-55,
Organism=Escherichia coli, GI87082258, Length=259, Percent_Identity=42.4710424710425, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1788867, Length=511, Percent_Identity=33.8551859099804, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI1789601, Length=153, Percent_Identity=40.5228758169935, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 79271; Mature: 79271

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPSPSDRLSGNRRPEDIDPPEAPRPPRRPALRHPGRIALAIAGVVLALGVLVLAINLYT
CCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHE
MPLSPSFQEPERSGFLIADAEGTVVATRGVTAGRPVALAEMPASLVNAVIAFEDRRFRDH
ECCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
WGVDPRGIARAIWVNLRSGGRTQGASTLTQQLVKNTLLTPEKTFTRKIQEAMLALWIERK
CCCCHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LTKDEILERYLNSLYLGAGSYGVDAAARRYFNKPVTDLSLAESAMIAGLIQAPARTGPTT
CCHHHHHHHHHHHHEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHH
ALDVARQRAELVLDVMRDQGLIGADEATWAKAHPASLAVPPVELPAYGAVSDWIADEARK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ALGPLSGDFLVVSTLDRRLQVLAQQTIQEGMAAEGAGLRATQAALVAMAPDGRVLAMVGG
HHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEECCCCCEEEEECC
RDYQESQFNRAVQARRQPGSIFKLFVYLTALSNNWRPDDPIDDTPLTIDGWSPENYGGGA
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCC
GHGSVPLRVAFAHSYNLAAVRLQEAVGREAVIATARSMGLKDDLQPLPSLALGTFPATLL
CCCCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
DLTSAFAAVAADRATVQPRVIEVLRTPGSGEIRPPVRQSGRAPWPRASALDLLNAVVTQG
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCC
TGRAAALGVPTYGKTGTTQDNRDAWFIGFAGNLVIGVWVGNDDETPMTGISGGGLPAKLW
CCCEEEECCCCCCCCCCCCCCCCEEEEEEECCEEEEEEECCCCCCCCCCCCCCCCHHHHH
QSFAARALAGGVAGSAPAAPIAAATTATLPAAAPPAPTPAPAVPSRQPFSAVPEAVVDTG
HHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHCCC
TLRLGGRVVRLEGVKGLTGRPARDMAGYIGDRSVTCRPAGRERWRCDVEGWDLSEVALFN
EEEECCEEEEEECCCCCCCCCHHHHHHHCCCCCEEECCCCCCCEEECCCCCCCHHEEEEC
GGARATADAPADLVAAERKARQAGRGVWGR
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIPSPSDRLSGNRRPEDIDPPEAPRPPRRPALRHPGRIALAIAGVVLALGVLVLAINLYT
CCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHE
MPLSPSFQEPERSGFLIADAEGTVVATRGVTAGRPVALAEMPASLVNAVIAFEDRRFRDH
ECCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
WGVDPRGIARAIWVNLRSGGRTQGASTLTQQLVKNTLLTPEKTFTRKIQEAMLALWIERK
CCCCHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LTKDEILERYLNSLYLGAGSYGVDAAARRYFNKPVTDLSLAESAMIAGLIQAPARTGPTT
CCHHHHHHHHHHHHEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHH
ALDVARQRAELVLDVMRDQGLIGADEATWAKAHPASLAVPPVELPAYGAVSDWIADEARK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ALGPLSGDFLVVSTLDRRLQVLAQQTIQEGMAAEGAGLRATQAALVAMAPDGRVLAMVGG
HHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEECCCCCEEEEECC
RDYQESQFNRAVQARRQPGSIFKLFVYLTALSNNWRPDDPIDDTPLTIDGWSPENYGGGA
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCC
GHGSVPLRVAFAHSYNLAAVRLQEAVGREAVIATARSMGLKDDLQPLPSLALGTFPATLL
CCCCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
DLTSAFAAVAADRATVQPRVIEVLRTPGSGEIRPPVRQSGRAPWPRASALDLLNAVVTQG
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCC
TGRAAALGVPTYGKTGTTQDNRDAWFIGFAGNLVIGVWVGNDDETPMTGISGGGLPAKLW
CCCEEEECCCCCCCCCCCCCCCCEEEEEEECCEEEEEEECCCCCCCCCCCCCCCCHHHHH
QSFAARALAGGVAGSAPAAPIAAATTATLPAAAPPAPTPAPAVPSRQPFSAVPEAVVDTG
HHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHCCC
TLRLGGRVVRLEGVKGLTGRPARDMAGYIGDRSVTCRPAGRERWRCDVEGWDLSEVALFN
EEEECCEEEEEECCCCCCCCCHHHHHHHCCCCCEEECCCCCCCEEECCCCCCCHHEEEEC
GGARATADAPADLVAAERKARQAGRGVWGR
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]