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The map label for this gene is katA [H]

Identifier: 83593824

GI number: 83593824

Start: 2894407

End: 2895861

Strand: Direct

Name: katA [H]

Synonym: Rru_A2489

Alternate gene names: 83593824

Gene position: 2894407-2895861 (Clockwise)

Preceding gene: 83593821

Following gene: 83593826

Centisome position: 66.49

GC content: 63.09

Gene sequence:

>1455_bases
ATGACCACGCGCCTGACCACCACCGCCGGTGCCCCGGTCGCCGATAATCAAAACAGCCTGACCGCCGGACCCCGGGGGCC
GGTGCTGCTGCAGGATTATCAGTTGATCGAGAAGCTGGCCCACCAGAACCGGGAACGCATTCCCGAACGCGTCGTCCACG
CCAAGGGCTGGGGCGCCCATGGCACCTTGACCATCACCCATGACATCAGCCGCTATACCCGAGCCAAGCTGTTCTCGGCG
GTCGGCAAAACGACACCGGTGCTCGCCCGCTTTTCGACGGTGGCGGGCGAATTGGGGGCGGCCGACGCCGAACGCGACGT
GCGCGGCTTTTCGCTGAAGTTCTATACCGAGGAAGGCAACTGGGATCTGGCGGGCAACAACACCCCGGTGTTCTTCGTGC
GCGATCCTTTGAAGTTTCCCGATTTCATCCATACCCAGAAACGCCATCCGCGCACCCATCTGCGCTCGCCCACCGCCATG
TGGGATTTCTGGTCGCTCAGCCCGGAAAGCCTGCATCAGGTCACCATCTTGATGAGCGATCGCGGTCTGCCGCTTGATCC
CATGCATATGAACGGCTACGGCAGCCACACCTATTCCTTCTGGAACGACGCCGGCGAGCGCTTTTGGGTGAAGTTCCACT
TCAAGACCCAACAGGGCCATGCTCATCTGACCAATGCCGCCGCCAAGGTCGTGGTCGGCGAGTCGCGCGAAAGCTATCAG
GAGGCGCTGTTTGGCACCATCGAGTCGGGTCACTTCCCGCGCTGGACGCTGTTTGTGCAGATCATGGCCGAACGCGAGGC
CGAAACCACCCCCTATAACCCCTTCGACCTCACCAAGGTCTGGCCGCACGGCGATTTTCCGCTGATCGAGGTCGGGGTGC
TGGAACTCAACCGCAACGCCGAGAACTATTTCGCCGAGATCGAGCAGGCGGCCTTTTCGCCGTCGAACGTCGTCCCGGGC
ATCGGCCATTCGCCCGACAAGATGCTTCAAGCCCGGGTGTTCGCCTATGCCGACGCCCATCGCTATCGCCTGGGCACCCA
TTACGAGGCCCTGCCGGTGAACGCCCCGCTCAGCCCGGTCAATCACTACCACAAAGACGGGCCGATGCGCTTTTTCCCCA
ATAATCCCAACGCCGACGCCTATTACGAGCCCAACAGCTTCGGTGGACCCAAAGAGGACCCCTCGGTCAAGGAGCCGCCG
CTGCGCATCAACGGCGATGCCGATCACTACAACCACCGCGAGGGCAACGACGATTACGTCCAGGTCGGCGCCCTCTTCGC
CCTGTTTGACGAGGGCGAGCGCCAGCGTCTGTTCTCCAATATCGCCGAGGCCATGGCCGGCGTGCCCGAGGAGATCATCC
GCCGCCAGTTGGTCCATTTCCACCGCGCCGATCCGGCTTACGGCGAGGGCGTGGCCAAGGCGCTGGGACTGGCCCCGGTT
TCCCAACCGGCCTGA

Upstream 100 bases:

>100_bases
AATAACCCAGTAAAGTTATGTATTTCCGCTGATAGATCGCCTCTAGGATGAGGGGTATCGGATCACGCCCTTAGCGCCAT
CCACTTTCGGGGAGAAGCCC

Downstream 100 bases:

>100_bases
CCGGCCCCTCCATCCCACCACCATCTCAAGGGAGCGACCCGCCCGGGCCGCTCCTTTTCTTAGCGGAAATAGGCCCCCGG
CGTCGTGCCGAGCAGCCGGC

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MTTRLTTTAGAPVADNQNSLTAGPRGPVLLQDYQLIEKLAHQNRERIPERVVHAKGWGAHGTLTITHDISRYTRAKLFSA
VGKTTPVLARFSTVAGELGAADAERDVRGFSLKFYTEEGNWDLAGNNTPVFFVRDPLKFPDFIHTQKRHPRTHLRSPTAM
WDFWSLSPESLHQVTILMSDRGLPLDPMHMNGYGSHTYSFWNDAGERFWVKFHFKTQQGHAHLTNAAAKVVVGESRESYQ
EALFGTIESGHFPRWTLFVQIMAEREAETTPYNPFDLTKVWPHGDFPLIEVGVLELNRNAENYFAEIEQAAFSPSNVVPG
IGHSPDKMLQARVFAYADAHRYRLGTHYEALPVNAPLSPVNHYHKDGPMRFFPNNPNADAYYEPNSFGGPKEDPSVKEPP
LRINGDADHYNHREGNDDYVQVGALFALFDEGERQRLFSNIAEAMAGVPEEIIRRQLVHFHRADPAYGEGVAKALGLAPV
SQPA

Sequences:

>Translated_484_residues
MTTRLTTTAGAPVADNQNSLTAGPRGPVLLQDYQLIEKLAHQNRERIPERVVHAKGWGAHGTLTITHDISRYTRAKLFSA
VGKTTPVLARFSTVAGELGAADAERDVRGFSLKFYTEEGNWDLAGNNTPVFFVRDPLKFPDFIHTQKRHPRTHLRSPTAM
WDFWSLSPESLHQVTILMSDRGLPLDPMHMNGYGSHTYSFWNDAGERFWVKFHFKTQQGHAHLTNAAAKVVVGESRESYQ
EALFGTIESGHFPRWTLFVQIMAEREAETTPYNPFDLTKVWPHGDFPLIEVGVLELNRNAENYFAEIEQAAFSPSNVVPG
IGHSPDKMLQARVFAYADAHRYRLGTHYEALPVNAPLSPVNHYHKDGPMRFFPNNPNADAYYEPNSFGGPKEDPSVKEPP
LRINGDADHYNHREGNDDYVQVGALFALFDEGERQRLFSNIAEAMAGVPEEIIRRQLVHFHRADPAYGEGVAKALGLAPV
SQPA
>Mature_483_residues
TTRLTTTAGAPVADNQNSLTAGPRGPVLLQDYQLIEKLAHQNRERIPERVVHAKGWGAHGTLTITHDISRYTRAKLFSAV
GKTTPVLARFSTVAGELGAADAERDVRGFSLKFYTEEGNWDLAGNNTPVFFVRDPLKFPDFIHTQKRHPRTHLRSPTAMW
DFWSLSPESLHQVTILMSDRGLPLDPMHMNGYGSHTYSFWNDAGERFWVKFHFKTQQGHAHLTNAAAKVVVGESRESYQE
ALFGTIESGHFPRWTLFVQIMAEREAETTPYNPFDLTKVWPHGDFPLIEVGVLELNRNAENYFAEIEQAAFSPSNVVPGI
GHSPDKMLQARVFAYADAHRYRLGTHYEALPVNAPLSPVNHYHKDGPMRFFPNNPNADAYYEPNSFGGPKEDPSVKEPPL
RINGDADHYNHREGNDDYVQVGALFALFDEGERQRLFSNIAEAMAGVPEEIIRRQLVHFHRADPAYGEGVAKALGLAPVS
QPA

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=482, Percent_Identity=52.2821576763486, Blast_Score=504, Evalue=1e-143,
Organism=Escherichia coli, GI48994891, Length=495, Percent_Identity=40.2020202020202, Blast_Score=324, Evalue=9e-90,
Organism=Caenorhabditis elegans, GI71998444, Length=473, Percent_Identity=51.1627906976744, Blast_Score=481, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI25151141, Length=475, Percent_Identity=50.7368421052632, Blast_Score=474, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI25147792, Length=475, Percent_Identity=50.5263157894737, Blast_Score=473, Evalue=1e-134,
Organism=Saccharomyces cerevisiae, GI6320462, Length=485, Percent_Identity=43.9175257731959, Blast_Score=385, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6321525, Length=510, Percent_Identity=37.4509803921569, Blast_Score=320, Evalue=2e-88,
Organism=Drosophila melanogaster, GI17981717, Length=482, Percent_Identity=46.8879668049792, Blast_Score=463, Evalue=1e-130,
Organism=Drosophila melanogaster, GI19920968, Length=482, Percent_Identity=42.7385892116183, Blast_Score=421, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 54318; Mature: 54187

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00437 CATALASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRLTTTAGAPVADNQNSLTAGPRGPVLLQDYQLIEKLAHQNRERIPERVVHAKGWGAH
CCCEEEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTLTITHDISRYTRAKLFSAVGKTTPVLARFSTVAGELGAADAERDVRGFSLKFYTEEGN
CEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCC
WDLAGNNTPVFFVRDPLKFPDFIHTQKRHPRTHLRSPTAMWDFWSLSPESLHQVTILMSD
EEECCCCCCEEEEECCCCCCHHHHHHCCCCHHHCCCCCCEEEECCCCHHHHEEEEEEEEC
RGLPLDPMHMNGYGSHTYSFWNDAGERFWVKFHFKTQQGHAHLTNAAAKVVVGESRESYQ
CCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEEEEECCCCCEEHHHHHEEEEECCCHHHHH
EALFGTIESGHFPRWTLFVQIMAEREAETTPYNPFDLTKVWPHGDFPLIEVGVLELNRNA
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECCCH
ENYFAEIEQAAFSPSNVVPGIGHSPDKMLQARVFAYADAHRYRLGTHYEALPVNAPLSPV
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEECCCCCEEEECCCCCCHH
NHYHKDGPMRFFPNNPNADAYYEPNSFGGPKEDPSVKEPPLRINGDADHYNHREGNDDYV
HHHCCCCCEEECCCCCCCCCEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEE
QVGALFALFDEGERQRLFSNIAEAMAGVPEEIIRRQLVHFHRADPAYGEGVAKALGLAPV
EHEEHEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
SQPA
CCCC
>Mature Secondary Structure 
TTRLTTTAGAPVADNQNSLTAGPRGPVLLQDYQLIEKLAHQNRERIPERVVHAKGWGAH
CCEEEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTLTITHDISRYTRAKLFSAVGKTTPVLARFSTVAGELGAADAERDVRGFSLKFYTEEGN
CEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCC
WDLAGNNTPVFFVRDPLKFPDFIHTQKRHPRTHLRSPTAMWDFWSLSPESLHQVTILMSD
EEECCCCCCEEEEECCCCCCHHHHHHCCCCHHHCCCCCCEEEECCCCHHHHEEEEEEEEC
RGLPLDPMHMNGYGSHTYSFWNDAGERFWVKFHFKTQQGHAHLTNAAAKVVVGESRESYQ
CCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEEEEECCCCCEEHHHHHEEEEECCCHHHHH
EALFGTIESGHFPRWTLFVQIMAEREAETTPYNPFDLTKVWPHGDFPLIEVGVLELNRNA
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECCCH
ENYFAEIEQAAFSPSNVVPGIGHSPDKMLQARVFAYADAHRYRLGTHYEALPVNAPLSPV
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEECCCCCEEEECCCCCCHH
NHYHKDGPMRFFPNNPNADAYYEPNSFGGPKEDPSVKEPPLRINGDADHYNHREGNDDYV
HHHCCCCCEEECCCCCCCCCEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEE
QVGALFALFDEGERQRLFSNIAEAMAGVPEEIIRRQLVHFHRADPAYGEGVAKALGLAPV
EHEEHEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
SQPA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8955300; 11481430 [H]