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The map label for this gene is cheA [H]

Identifier: 83593662

GI number: 83593662

Start: 2696616

End: 2699204

Strand: Direct

Name: cheA [H]

Synonym: Rru_A2327

Alternate gene names: 83593662

Gene position: 2696616-2699204 (Clockwise)

Preceding gene: 83593661

Following gene: 83593663

Centisome position: 61.95

GC content: 68.02

Gene sequence:

>2589_bases
ATGAGCACGCCGCTGCTGCTCCGCTTCCTCTCCGAGGCCCGCGACCTGTTGCAGACCGCCGCCAGCGGCTTGCTGGCGCT
CGAAAAGACGCCGGGCGACGACGCCGCCCTCAACGAGGTGTTTCGCTCGGTTCACACCTTGAAGGGATCGGTCGGGCTGT
TCGACTACCCGGCCTTCACCAAACTGGTTCATGCCGGCGAAGATGTTCTGAGCGCGGTGCGCGCCGGACAGGTGGCGCTG
ACCTCCGAACTGGTCGATCTGCTGCTCGATACCCTCGATCAGGTCGGAGCCTGGGTCGATGCGATCGAGCGCTCCGGGCT
CCTGCCCGATGGCGCCGAGGGCCTCTCTCTCGCCCTGACCACCAGCCTGCGGGCGACCCTGCCCCGGGAACACGGCGCCG
AGCCGACCTCCGCGCCCGAGCCGACGGAAGCACCGGTCTCCATCGATCACCTCGCCCTCCTGCCGGAGGCGGATCGGCTG
GCCGCGTTCCGGGCGGCCCTCTGCGGAGCCCCCTTGCTGTCTTTGGACTACGCTCCCGCCGAGGATTGCTTTTTCAGCGG
TGAGGACCCGGTCAATCTGTTCCGCCAGATACCAGACCTGTTCTCTCTGGTGATCGAGCCGCGAACCCCCTGGCAAAGCG
TCGAAACGGTCGATCCCTATTGCTGCCTGCTGCGCCTGCGGGCTCTCTGCGGCGGGAACAAGACCGCGATCGAGCAGCTT
TTTCGCTATGTCATCGAACAGGTGACGGTCCATACGGTGCCGGCCCATCTGCTGGTGATCCCCCAAGGGGAGCGCAATGA
CGGCCCGGTCTACGGCGATTTCGTCGAGGAGGCCTCGACCCATCTCGCCAAGGCCGACTGGCCGGCTTTGCGCCGGGCGG
TCGGCGCCTTGCTAGACCTCACCGCCCGCCCGTTGTTCGTCGCCTCGGCCCTGAGGTGGCTCGACGCGGTCTTGTCGGTC
CCGACGCCCGATCCGGGGTGGGTCGAGGCACTGATCGCGGCGGTCGCCCACGGCAACGCGGTGGTCTTGCCGCCGGCCGG
CACGGGCGCGGCCTCCGCCCGCTCCAGCGCCGCCCTGTCGGCCACCATCCTGTCGATCCTTGACGGCCAGCGGGTGATCC
TCGAGATGCCCCGGGACGAGGGGCTCCCCGGTCGTCTGGCCTCGGTGGCGCGCACGGTCGACAATGTTCTGCGCGCCGCT
GGCCATGACACCGCGCCGTGGACCGGGGCGACGGCGGCGGCGGGCCAAAGCGGGTCGGCCGCGCCGATGCTGGCCTTTCT
CGCCGCCCTTTTCGAGACCTCCGAAACGACGAACGAAACGGCGAGCGAAACGGCGAGCGAAACGGTGGGCGCCCCGCCTC
CCGAGGGGGGGGAGGCGCTCGGCCCGGTCCTCGCCGACCAGCGGCCGGCCAACCGCGTGCTGAAAGTTGATCAGGCCAAG
ATCGACACCCTGATGGCCTTGATCGGCGAATTGGTGGTGTCGAAGAACAGCCTGCCGTTCCTGGCGCGGCGGGCCGAGGA
AGTCCATGGTTCACGCGAGATGGGGCGCGAGATCAAGGACACCTTCGCCGTGGTCGACCGCTTGGCCCAGGAGATGCAGG
CCGCCATCATGGCCGTCCGCATGCTGCCGGTCTCGGAGGTCTTCGAACGCTTCCCCCGGCTGGTGCGCGACATCGCCCGC
AAGCTGGGCAAGCACATCGACTTGGTGATCGAGGGGGAGGATACCGCCGCCGACAAGACGATCGTCGAGATGCTGGGAGA
CCCGTTGCTCCACATCATCCGCAATTCCCTTGATCACGGCATTGAATCGCCGGAGGAGCGCGAGGCCGCCGGCAAGCCGC
CGACGGCCCGCGTCCTGGTCAAGGCGTTCCACGACAGTGATCAGGTGGTGATCGAGGTTTCCGACGATGGCCGCGGCATC
GACCCGGTCAAGATCCGCGCCGCGGCGGTCGCCAAGGGCGTGATCGAGGCCGAGCGAGCCGCCCGGCTGAGCGACCAGGA
GGCGGTCAATCTGGTGTTCCTTCCCGGCTTCTCAACCGCCGGCCAGGTCTCCGACCTGTCGGGGCGCGGCGTCGGCATGG
ACGTGGTGGTCTCCACGATGGACAAGGCCAACGGCGTGGTCAGCCTGTCCTCGACCCCGGGCCTCGGCACCACCGTCCGC
CTGTCGCTGCCGCTGAGCATGGCGGTGACCCGGGTGATGATGGTCGAGGCCGGCGGCGGCATGCTGTTTGGCATCCCCAT
GGACCATATCGCCCAAACGGTGCGGATCCCGCGCAAGGCGGTCCGCCGGATCAAGCAGTCGGAAGCCTTCGTCCTGCGCG
ACGCCATCGTGCCACTGGTGCGGCTCGACACCCTGCTCGGCCTCGCCCCCCCTGTCTGGTTCGGCGATGAGTCGCAAGAG
GACGCGGTCTTGGTCGTGCGGGTCGGCAATGCCCTGACCGGTTTGGTCGTCGACCATTTCCGCGAGGGAATGGATATCAT
TTTGAAGCCCTTCGATGGCATCCTGGCCGGCCTTCCCGGGTATTCGGGCACCGCGCTGCTCGGCGATGGCCGGGTCTTGC
TGGTGCTCAATCTGAAGGAGCTGTTTTGA

Upstream 100 bases:

>100_bases
CCCTCAAGGCCTTCGAGGCCGGGGCGAATTATTATCTGGTCAAGCCGGTCGCTCCGGCGATGCTGACCGAGGTCGCTCAA
TTGCTGGCGGGGGTCGGTCG

Downstream 100 bases:

>100_bases
GATGCCGATCCGGACCAGCAAGACCACCATCACGATCGAAGGCGCCTGCACCGTCGAGGACGCCCTGCCTCTGCTCGAAG
CGTTGCAGGCGACCCCCAAG

Product: CheA Signal transduction histidine Kinases (STHK)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 862; Mature: 861

Protein sequence:

>862_residues
MSTPLLLRFLSEARDLLQTAASGLLALEKTPGDDAALNEVFRSVHTLKGSVGLFDYPAFTKLVHAGEDVLSAVRAGQVAL
TSELVDLLLDTLDQVGAWVDAIERSGLLPDGAEGLSLALTTSLRATLPREHGAEPTSAPEPTEAPVSIDHLALLPEADRL
AAFRAALCGAPLLSLDYAPAEDCFFSGEDPVNLFRQIPDLFSLVIEPRTPWQSVETVDPYCCLLRLRALCGGNKTAIEQL
FRYVIEQVTVHTVPAHLLVIPQGERNDGPVYGDFVEEASTHLAKADWPALRRAVGALLDLTARPLFVASALRWLDAVLSV
PTPDPGWVEALIAAVAHGNAVVLPPAGTGAASARSSAALSATILSILDGQRVILEMPRDEGLPGRLASVARTVDNVLRAA
GHDTAPWTGATAAAGQSGSAAPMLAFLAALFETSETTNETASETASETVGAPPPEGGEALGPVLADQRPANRVLKVDQAK
IDTLMALIGELVVSKNSLPFLARRAEEVHGSREMGREIKDTFAVVDRLAQEMQAAIMAVRMLPVSEVFERFPRLVRDIAR
KLGKHIDLVIEGEDTAADKTIVEMLGDPLLHIIRNSLDHGIESPEEREAAGKPPTARVLVKAFHDSDQVVIEVSDDGRGI
DPVKIRAAAVAKGVIEAERAARLSDQEAVNLVFLPGFSTAGQVSDLSGRGVGMDVVVSTMDKANGVVSLSSTPGLGTTVR
LSLPLSMAVTRVMMVEAGGGMLFGIPMDHIAQTVRIPRKAVRRIKQSEAFVLRDAIVPLVRLDTLLGLAPPVWFGDESQE
DAVLVVRVGNALTGLVVDHFREGMDIILKPFDGILAGLPGYSGTALLGDGRVLLVLNLKELF

Sequences:

>Translated_862_residues
MSTPLLLRFLSEARDLLQTAASGLLALEKTPGDDAALNEVFRSVHTLKGSVGLFDYPAFTKLVHAGEDVLSAVRAGQVAL
TSELVDLLLDTLDQVGAWVDAIERSGLLPDGAEGLSLALTTSLRATLPREHGAEPTSAPEPTEAPVSIDHLALLPEADRL
AAFRAALCGAPLLSLDYAPAEDCFFSGEDPVNLFRQIPDLFSLVIEPRTPWQSVETVDPYCCLLRLRALCGGNKTAIEQL
FRYVIEQVTVHTVPAHLLVIPQGERNDGPVYGDFVEEASTHLAKADWPALRRAVGALLDLTARPLFVASALRWLDAVLSV
PTPDPGWVEALIAAVAHGNAVVLPPAGTGAASARSSAALSATILSILDGQRVILEMPRDEGLPGRLASVARTVDNVLRAA
GHDTAPWTGATAAAGQSGSAAPMLAFLAALFETSETTNETASETASETVGAPPPEGGEALGPVLADQRPANRVLKVDQAK
IDTLMALIGELVVSKNSLPFLARRAEEVHGSREMGREIKDTFAVVDRLAQEMQAAIMAVRMLPVSEVFERFPRLVRDIAR
KLGKHIDLVIEGEDTAADKTIVEMLGDPLLHIIRNSLDHGIESPEEREAAGKPPTARVLVKAFHDSDQVVIEVSDDGRGI
DPVKIRAAAVAKGVIEAERAARLSDQEAVNLVFLPGFSTAGQVSDLSGRGVGMDVVVSTMDKANGVVSLSSTPGLGTTVR
LSLPLSMAVTRVMMVEAGGGMLFGIPMDHIAQTVRIPRKAVRRIKQSEAFVLRDAIVPLVRLDTLLGLAPPVWFGDESQE
DAVLVVRVGNALTGLVVDHFREGMDIILKPFDGILAGLPGYSGTALLGDGRVLLVLNLKELF
>Mature_861_residues
STPLLLRFLSEARDLLQTAASGLLALEKTPGDDAALNEVFRSVHTLKGSVGLFDYPAFTKLVHAGEDVLSAVRAGQVALT
SELVDLLLDTLDQVGAWVDAIERSGLLPDGAEGLSLALTTSLRATLPREHGAEPTSAPEPTEAPVSIDHLALLPEADRLA
AFRAALCGAPLLSLDYAPAEDCFFSGEDPVNLFRQIPDLFSLVIEPRTPWQSVETVDPYCCLLRLRALCGGNKTAIEQLF
RYVIEQVTVHTVPAHLLVIPQGERNDGPVYGDFVEEASTHLAKADWPALRRAVGALLDLTARPLFVASALRWLDAVLSVP
TPDPGWVEALIAAVAHGNAVVLPPAGTGAASARSSAALSATILSILDGQRVILEMPRDEGLPGRLASVARTVDNVLRAAG
HDTAPWTGATAAAGQSGSAAPMLAFLAALFETSETTNETASETASETVGAPPPEGGEALGPVLADQRPANRVLKVDQAKI
DTLMALIGELVVSKNSLPFLARRAEEVHGSREMGREIKDTFAVVDRLAQEMQAAIMAVRMLPVSEVFERFPRLVRDIARK
LGKHIDLVIEGEDTAADKTIVEMLGDPLLHIIRNSLDHGIESPEEREAAGKPPTARVLVKAFHDSDQVVIEVSDDGRGID
PVKIRAAAVAKGVIEAERAARLSDQEAVNLVFLPGFSTAGQVSDLSGRGVGMDVVVSTMDKANGVVSLSSTPGLGTTVRL
SLPLSMAVTRVMMVEAGGGMLFGIPMDHIAQTVRIPRKAVRRIKQSEAFVLRDAIVPLVRLDTLLGLAPPVWFGDESQED
AVLVVRVGNALTGLVVDHFREGMDIILKPFDGILAGLPGYSGTALLGDGRVLLVLNLKELF

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=456, Percent_Identity=34.4298245614035, Blast_Score=244, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 91586; Mature: 91455

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPLLLRFLSEARDLLQTAASGLLALEKTPGDDAALNEVFRSVHTLKGSVGLFDYPAFT
CCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHH
KLVHAGEDVLSAVRAGQVALTSELVDLLLDTLDQVGAWVDAIERSGLLPDGAEGLSLALT
HHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
TSLRATLPREHGAEPTSAPEPTEAPVSIDHLALLPEADRLAAFRAALCGAPLLSLDYAPA
HHHHHHCCHHCCCCCCCCCCCCCCCCCHHHEEECCCHHHHHHHHHHHHCCCHHCCCCCCH
EDCFFSGEDPVNLFRQIPDLFSLVIEPRTPWQSVETVDPYCCLLRLRALCGGNKTAIEQL
HHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
FRYVIEQVTVHTVPAHLLVIPQGERNDGPVYGDFVEEASTHLAKADWPALRRAVGALLDL
HHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TARPLFVASALRWLDAVLSVPTPDPGWVEALIAAVAHGNAVVLPPAGTGAASARSSAALS
HCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHH
ATILSILDGQRVILEMPRDEGLPGRLASVARTVDNVLRAAGHDTAPWTGATAAAGQSGSA
HHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
APMLAFLAALFETSETTNETASETASETVGAPPPEGGEALGPVLADQRPANRVLKVDQAK
HHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHCCHHCCCCCHHHHHHHHHHH
IDTLMALIGELVVSKNSLPFLARRAEEVHGSREMGREIKDTFAVVDRLAQEMQAAIMAVR
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLPVSEVFERFPRLVRDIARKLGKHIDLVIEGEDTAADKTIVEMLGDPLLHIIRNSLDHG
HCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHC
IESPEEREAAGKPPTARVLVKAFHDSDQVVIEVSDDGRGIDPVKIRAAAVAKGVIEAERA
CCCCHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
ARLSDQEAVNLVFLPGFSTAGQVSDLSGRGVGMDVVVSTMDKANGVVSLSSTPGLGTTVR
HHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCEEEE
LSLPLSMAVTRVMMVEAGGGMLFGIPMDHIAQTVRIPRKAVRRIKQSEAFVLRDAIVPLV
EECCHHHHHHHHHHEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLDTLLGLAPPVWFGDESQEDAVLVVRVGNALTGLVVDHFREGMDIILKPFDGILAGLPG
HHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCHHEECCCHHHHHHCCCC
YSGTALLGDGRVLLVLNLKELF
CCCCEEECCCCEEEEEECHHHC
>Mature Secondary Structure 
STPLLLRFLSEARDLLQTAASGLLALEKTPGDDAALNEVFRSVHTLKGSVGLFDYPAFT
CCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHH
KLVHAGEDVLSAVRAGQVALTSELVDLLLDTLDQVGAWVDAIERSGLLPDGAEGLSLALT
HHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
TSLRATLPREHGAEPTSAPEPTEAPVSIDHLALLPEADRLAAFRAALCGAPLLSLDYAPA
HHHHHHCCHHCCCCCCCCCCCCCCCCCHHHEEECCCHHHHHHHHHHHHCCCHHCCCCCCH
EDCFFSGEDPVNLFRQIPDLFSLVIEPRTPWQSVETVDPYCCLLRLRALCGGNKTAIEQL
HHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
FRYVIEQVTVHTVPAHLLVIPQGERNDGPVYGDFVEEASTHLAKADWPALRRAVGALLDL
HHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TARPLFVASALRWLDAVLSVPTPDPGWVEALIAAVAHGNAVVLPPAGTGAASARSSAALS
HCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHH
ATILSILDGQRVILEMPRDEGLPGRLASVARTVDNVLRAAGHDTAPWTGATAAAGQSGSA
HHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
APMLAFLAALFETSETTNETASETASETVGAPPPEGGEALGPVLADQRPANRVLKVDQAK
HHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHCCHHCCCCCHHHHHHHHHHH
IDTLMALIGELVVSKNSLPFLARRAEEVHGSREMGREIKDTFAVVDRLAQEMQAAIMAVR
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLPVSEVFERFPRLVRDIARKLGKHIDLVIEGEDTAADKTIVEMLGDPLLHIIRNSLDHG
HCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHC
IESPEEREAAGKPPTARVLVKAFHDSDQVVIEVSDDGRGIDPVKIRAAAVAKGVIEAERA
CCCCHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
ARLSDQEAVNLVFLPGFSTAGQVSDLSGRGVGMDVVVSTMDKANGVVSLSSTPGLGTTVR
HHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCEEEE
LSLPLSMAVTRVMMVEAGGGMLFGIPMDHIAQTVRIPRKAVRRIKQSEAFVLRDAIVPLV
EECCHHHHHHHHHHEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLDTLLGLAPPVWFGDESQEDAVLVVRVGNALTGLVVDHFREGMDIILKPFDGILAGLPG
HHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCHHEECCCHHHHHHCCCC
YSGTALLGDGRVLLVLNLKELF
CCCCEEECCCCEEEEEECHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]