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The map label for this gene is deoR [H]

Identifier: 83593639

GI number: 83593639

Start: 2666101

End: 2666880

Strand: Direct

Name: deoR [H]

Synonym: Rru_A2304

Alternate gene names: 83593639

Gene position: 2666101-2666880 (Clockwise)

Preceding gene: 83593631

Following gene: 83593640

Centisome position: 61.25

GC content: 64.62

Gene sequence:

>780_bases
ATGCGAACCATGAGTTATCGACGGGTGGAACGTCTGGCGATGCTGGCAACGGCCCTGGAGGCCGGCGGCTCTTTACGCCT
GAAGGAAGCCGCGAAGATGCTGGGCGTTTCGGAAATGACCGTGCGCCGCGATATCGCCACCGGGGATGGCAGCCTGACCT
ATCTGGGCGGCTATATCGTCGCCGGCCAGGAGACGCCGGGGGGGATGGGCTATCTTTTCGCCACCGAACTGGCCTCCCAT
ACCGAAAAGAAGCGCGACGCCTGCACCCTTGCCGCCTCGCTGATCGAACCGGGCGACACGGTGTTTCTCGACTGCGGCAC
CACCATGCCCCATCTGGCCAGCCGCATTCCCACCGACCTGCGCCTGACGGTGGTCTGCTACGCCATCAATGTCGCCGAGA
TCCTGTGCAAGAAGCCCAATTTGAAAGTTGTGCTGCTGGGCGGCATCTACCACCCCTCCAGCGCCACCTTTTCCAGCGAG
GAGGCCCTGGGCACCCTGGCCAATATCGGCATCAACAAGGCCTTCATCTCGGCCGGCGGGCTGCATGCCGACCGCGGGGT
CAGTTGCTCGAACTTCCACGAGGTGCCGATCAAGCGCGCCGCCATGCAAAACGCCGTGCGCCGCATCGTCGTTCTCGATT
CAACCAAATTCGGCCGGGTCAAACCGGCCTTCATCGGCCAGATCGACGATTTCGACACCGTGGTCAGCGACGCCGCCGTC
CCCGCCCCCTGGCGCGAAACCCTTCCCCCCGGCGTCCGCCTGCTGATGCCCGCGCCCTGA

Upstream 100 bases:

>100_bases
CAGAGAGCGCGGCCAAAATCGATGATTGCGGTTTTTGGCGATTTCGCCGCTCTCCTCTTATGAGTCTAGATCCACCAAGG
GTGATCTGGCACGGAAGGCG

Downstream 100 bases:

>100_bases
GGGGCGGGGCGCGGAGAACCGGGGCGCCGGGCGCGATCTCCCCTGTCTGGGGAAGGCCAGCCCCGAATATAATGCCCGAC
GAACCACTGCGAGGAAGAGG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MRTMSYRRVERLAMLATALEAGGSLRLKEAAKMLGVSEMTVRRDIATGDGSLTYLGGYIVAGQETPGGMGYLFATELASH
TEKKRDACTLAASLIEPGDTVFLDCGTTMPHLASRIPTDLRLTVVCYAINVAEILCKKPNLKVVLLGGIYHPSSATFSSE
EALGTLANIGINKAFISAGGLHADRGVSCSNFHEVPIKRAAMQNAVRRIVVLDSTKFGRVKPAFIGQIDDFDTVVSDAAV
PAPWRETLPPGVRLLMPAP

Sequences:

>Translated_259_residues
MRTMSYRRVERLAMLATALEAGGSLRLKEAAKMLGVSEMTVRRDIATGDGSLTYLGGYIVAGQETPGGMGYLFATELASH
TEKKRDACTLAASLIEPGDTVFLDCGTTMPHLASRIPTDLRLTVVCYAINVAEILCKKPNLKVVLLGGIYHPSSATFSSE
EALGTLANIGINKAFISAGGLHADRGVSCSNFHEVPIKRAAMQNAVRRIVVLDSTKFGRVKPAFIGQIDDFDTVVSDAAV
PAPWRETLPPGVRLLMPAP
>Mature_259_residues
MRTMSYRRVERLAMLATALEAGGSLRLKEAAKMLGVSEMTVRRDIATGDGSLTYLGGYIVAGQETPGGMGYLFATELASH
TEKKRDACTLAASLIEPGDTVFLDCGTTMPHLASRIPTDLRLTVVCYAINVAEILCKKPNLKVVLLGGIYHPSSATFSSE
EALGTLANIGINKAFISAGGLHADRGVSCSNFHEVPIKRAAMQNAVRRIVVLDSTKFGRVKPAFIGQIDDFDTVVSDAAV
PAPWRETLPPGVRLLMPAP

Specific function: This protein is one of the repressors that regulate the expression of deoCABD genes, which encode nucleotide and deoxy ribonucleotide catabolizing enzymes. It also negatively regulates the expression of nupG (a transport protein) and tsx (a pore- forming

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787063, Length=234, Percent_Identity=41.8803418803419, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1790753, Length=265, Percent_Identity=26.0377358490566, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI226510968, Length=237, Percent_Identity=28.2700421940928, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=28.5714285714286, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787540, Length=224, Percent_Identity=28.125, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789059, Length=244, Percent_Identity=25, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789829, Length=247, Percent_Identity=25.9109311740891, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI87082344, Length=254, Percent_Identity=25.5905511811024, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789170, Length=216, Percent_Identity=24.0740740740741, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27677; Mature: 27677

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTMSYRRVERLAMLATALEAGGSLRLKEAAKMLGVSEMTVRRDIATGDGSLTYLGGYIV
CCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEEEEE
AGQETPGGMGYLFATELASHTEKKRDACTLAASLIEPGDTVFLDCGTTMPHLASRIPTDL
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCC
RLTVVCYAINVAEILCKKPNLKVVLLGGIYHPSSATFSSEEALGTLANIGINKAFISAGG
EEEEEEEHHHHHHHHHCCCCCEEEEEECEECCCCCCCCCHHHHHHHHHCCCCHHHHCCCC
LHADRGVSCSNFHEVPIKRAAMQNAVRRIVVLDSTKFGRVKPAFIGQIDDFDTVVSDAAV
CCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCHHHHCCCCCHHHHHHCCCC
PAPWRETLPPGVRLLMPAP
CCCHHHCCCCCCEEEECCC
>Mature Secondary Structure
MRTMSYRRVERLAMLATALEAGGSLRLKEAAKMLGVSEMTVRRDIATGDGSLTYLGGYIV
CCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEEEEE
AGQETPGGMGYLFATELASHTEKKRDACTLAASLIEPGDTVFLDCGTTMPHLASRIPTDL
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCC
RLTVVCYAINVAEILCKKPNLKVVLLGGIYHPSSATFSSEEALGTLANIGINKAFISAGG
EEEEEEEHHHHHHHHHCCCCCEEEEEECEECCCCCCCCCHHHHHHHHHCCCCHHHHCCCC
LHADRGVSCSNFHEVPIKRAAMQNAVRRIVVLDSTKFGRVKPAFIGQIDDFDTVVSDAAV
CCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCHHHHCCCCCHHHHHHCCCC
PAPWRETLPPGVRLLMPAP
CCCHHHCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]