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The map label for this gene is yafC [H]

Identifier: 83593592

GI number: 83593592

Start: 2618273

End: 2619187

Strand: Direct

Name: yafC [H]

Synonym: Rru_A2257

Alternate gene names: 83593592

Gene position: 2618273-2619187 (Clockwise)

Preceding gene: 83593591

Following gene: 83593596

Centisome position: 60.15

GC content: 64.59

Gene sequence:

>915_bases
ATGGATATCCTGAGCGGTATGCGCCTGCTGAGCCGGGTGGTCGAGGCGGGGAGTTTTTCCGAAGCCGGCCGCCTGTTGGG
CATGGCGCCCTCGTCGGTGTCACGCCAAGTCAGCGCCCTGGAAGACACCCTTGGCACCCAGTTGCTCAACCGCACCACCC
GTCGGCTCAGCCTGACCGAGGCCGGCGGCCTGTTTCACGACCGGGCCCTGCGCATCCTGGCCGATGTCGAAGACGCGACC
CGGGTGGTCTCCTCGCTGGAATCGGCGCCGCGCGGTACCTTGAAGCTCAATGTGCCGGTGGGCTTTGGCAATTACCACGT
CGCCCCCGCCCTGCCGCTGTTTCTCGCCCGCTACCCGGATCTGACCGTCGATCTGACGCTTTCCGACCACTTCATCGATC
TGATCGAGGAAGGCGTCGATGTCGCCGTGCGCATCGGCGCCCTGCGCGATTCCAGTCTGGTCGCCCGCCGGCTGGCCGAT
AATCGACGGATGGTTTATGGCAGCCCCGATTACCTGCGACGCATGGGTACCCCCGAGACCCCCCATGATCTGACCGCCCA
CCGCTGCATCGCCTATCGCTACCGCCCCGGTCCCCAGGGCTGGCTGTTCGAGCGCGACGGCATCCGCCTTGACATCACCG
TCACCGGGCCTTTGACCGCCAACAACTCGGAAAGCCTGCATAAGATGATTTTGGGGGGCTCGGGTCTGGCGATGCTGCCG
ACCTGGATGGCCTATAGCGATGTCAAAAGCGGCCTGCTGGTGCCCTTGCTCGGTGATTGGACGATGTCGCCGACCAGCCT
GGAAAGCGCCATTCACGTCGTCTATCCCGAAAGCCGCCACCTGTCGGCCAAGGTCCGCGCCTTCATCGATTTCATGGCCG
ACCACATCGGCAAGCCCCCCTATTGGGAGCGCTAA

Upstream 100 bases:

>100_bases
TTAACGGAGTAGGATATAACCCTCGGCCCCTGCGGAAAAGCCACAGGATGGGACAGTCTCTTTTGCGTCTTGCGCAAAAA
CGAAAAGGGTCTCGGACATC

Downstream 100 bases:

>100_bases
AACCCACGAAGGCCCCCCGGTCGGCAAACCGGGGGGCCTTCGCGTAAGGCTATGGGCGTAAACTCAGTGCAGGTCGCGTT
CCATCTTGGTCGCGGCCTTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MDILSGMRLLSRVVEAGSFSEAGRLLGMAPSSVSRQVSALEDTLGTQLLNRTTRRLSLTEAGGLFHDRALRILADVEDAT
RVVSSLESAPRGTLKLNVPVGFGNYHVAPALPLFLARYPDLTVDLTLSDHFIDLIEEGVDVAVRIGALRDSSLVARRLAD
NRRMVYGSPDYLRRMGTPETPHDLTAHRCIAYRYRPGPQGWLFERDGIRLDITVTGPLTANNSESLHKMILGGSGLAMLP
TWMAYSDVKSGLLVPLLGDWTMSPTSLESAIHVVYPESRHLSAKVRAFIDFMADHIGKPPYWER

Sequences:

>Translated_304_residues
MDILSGMRLLSRVVEAGSFSEAGRLLGMAPSSVSRQVSALEDTLGTQLLNRTTRRLSLTEAGGLFHDRALRILADVEDAT
RVVSSLESAPRGTLKLNVPVGFGNYHVAPALPLFLARYPDLTVDLTLSDHFIDLIEEGVDVAVRIGALRDSSLVARRLAD
NRRMVYGSPDYLRRMGTPETPHDLTAHRCIAYRYRPGPQGWLFERDGIRLDITVTGPLTANNSESLHKMILGGSGLAMLP
TWMAYSDVKSGLLVPLLGDWTMSPTSLESAIHVVYPESRHLSAKVRAFIDFMADHIGKPPYWER
>Mature_304_residues
MDILSGMRLLSRVVEAGSFSEAGRLLGMAPSSVSRQVSALEDTLGTQLLNRTTRRLSLTEAGGLFHDRALRILADVEDAT
RVVSSLESAPRGTLKLNVPVGFGNYHVAPALPLFLARYPDLTVDLTLSDHFIDLIEEGVDVAVRIGALRDSSLVARRLAD
NRRMVYGSPDYLRRMGTPETPHDLTAHRCIAYRYRPGPQGWLFERDGIRLDITVTGPLTANNSESLHKMILGGSGLAMLP
TWMAYSDVKSGLLVPLLGDWTMSPTSLESAIHVVYPESRHLSAKVRAFIDFMADHIGKPPYWER

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=39.2361111111111, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1789639, Length=296, Percent_Identity=33.7837837837838, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789440, Length=298, Percent_Identity=30.8724832214765, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI87081978, Length=297, Percent_Identity=33.6700336700337, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI145693193, Length=296, Percent_Identity=33.1081081081081, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787128, Length=282, Percent_Identity=29.4326241134752, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1787589, Length=282, Percent_Identity=30.1418439716312, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789173, Length=285, Percent_Identity=26.3157894736842, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786448, Length=307, Percent_Identity=23.4527687296417, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI157672245, Length=146, Percent_Identity=30.8219178082192, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790011, Length=264, Percent_Identity=24.6212121212121, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788706, Length=264, Percent_Identity=24.2424242424242, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788481, Length=295, Percent_Identity=21.6949152542373, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787806, Length=251, Percent_Identity=26.6932270916335, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33521; Mature: 33521

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS00024 HEMOPEXIN ; PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILSGMRLLSRVVEAGSFSEAGRLLGMAPSSVSRQVSALEDTLGTQLLNRTTRRLSLTE
CCHHHHHHHHHHHHHCCCCHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEHH
AGGLFHDRALRILADVEDATRVVSSLESAPRGTLKLNVPVGFGNYHVAPALPLFLARYPD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEHHHHHHHHHHCCCC
LTVDLTLSDHFIDLIEEGVDVAVRIGALRDSSLVARRLADNRRMVYGSPDYLRRMGTPET
CEEEEEEHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCEEEECCHHHHHHCCCCCC
PHDLTAHRCIAYRYRPGPQGWLFERDGIRLDITVTGPLTANNSESLHKMILGGSGLAMLP
CCCHHHHHEEEEEECCCCCCCEEECCCEEEEEEEECCCCCCCHHHHHHHHHCCCCHHHHH
TWMAYSDVKSGLLVPLLGDWTMSPTSLESAIHVVYPESRHLSAKVRAFIDFMADHIGKPP
HHHHHHHHHCCEEEEEECCCCCCCHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCC
YWER
CCCC
>Mature Secondary Structure
MDILSGMRLLSRVVEAGSFSEAGRLLGMAPSSVSRQVSALEDTLGTQLLNRTTRRLSLTE
CCHHHHHHHHHHHHHCCCCHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEHH
AGGLFHDRALRILADVEDATRVVSSLESAPRGTLKLNVPVGFGNYHVAPALPLFLARYPD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEHHHHHHHHHHCCCC
LTVDLTLSDHFIDLIEEGVDVAVRIGALRDSSLVARRLADNRRMVYGSPDYLRRMGTPET
CEEEEEEHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCEEEECCHHHHHHCCCCCC
PHDLTAHRCIAYRYRPGPQGWLFERDGIRLDITVTGPLTANNSESLHKMILGGSGLAMLP
CCCHHHHHEEEEEECCCCCCCEEECCCEEEEEEEECCCCCCCHHHHHHHHHCCCCHHHHH
TWMAYSDVKSGLLVPLLGDWTMSPTSLESAIHVVYPESRHLSAKVRAFIDFMADHIGKPP
HHHHHHHHHCCEEEEEECCCCCCCHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCC
YWER
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]