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The map label for this gene is oxlT [H]

Identifier: 83590430

GI number: 83590430

Start: 1624610

End: 1625905

Strand: Reverse

Name: oxlT [H]

Synonym: Moth_1590

Alternate gene names: 83590430

Gene position: 1625905-1624610 (Counterclockwise)

Preceding gene: 83590431

Following gene: 83590429

Centisome position: 61.85

GC content: 50.39

Gene sequence:

>1296_bases
ATGTCAATCCAGAACCCTGAGACCCCGTTCGGGCCCCGGGAAGTACCCAAACCTTTTTTCGAGAATAAATGGGTGCAATT
GATTATTGCCATGATCGGCATGATCATGATTGCCAACCTCCAGTATGCCTGGACTCTCTTTGTGCCGGAAGTAGTAAAAG
GTCTTAACTCAACGAAAGCTGCAGTCCAGATGGGGTTTTCCCTCTTTATCGCCTTTGAGAGCTGGGGCCAGCCTATTGCC
GGATACTTCATGGATCGCTACAGCCCCCGGGCTTTGCTGACTGTAGCCGCCTTGATGATCGGTATTGGATGGGCCGGTAT
GGGATTAGTCAAATCCCTTGGTGCTTTGTATTTCTTATATAGTATGGCGGGTGTGGGTGCAGCCCTGATCTATAGCGGCT
CCATTGCCTCGGGCGTGCGCTGGTTTGAGGCCTCCAAGAGGGGAATGGCCTCCGGACTGGTAGCTGCCGCTTTCGGTTCC
GGGGCCGCCCTCTTTATCCCCTTTATCGCTATCATATTGAAAAAGCAGGGTTATAATTCAGCATTCGTAACTACAGGCGT
TATCCAGGGAATTATCGCCTTGATTGCCGCCCAGTTCATGCGTTTCCCTGCTAAACCTAAGACGAGTAGCTCCAGTACGG
CGAAAGCCCAGGTTTCCGCCAGCCAGCGTGATTTTACTACAGTGGAAATGTTTAAAACAGCTCATTTCTGGATTATTTAT
TTAATGTTCTTGTTTATTTGTACCGGCGGCATGATTGTAACGGCCCAGACAAAACCCTTTGGTACGGAGGCGGGTATAGC
TGCCAGCATCATTGTGACAGCAGCCACAATCAATACCATTGCCAATGGTGCCGGGCGGATAATCTGGGGTATGATTTCCG
ACAAACTGGGGCGTTACCAGACAATGTTTGTGGCCTTTACCATTAACGCCATCGCCATGGCCCTGGTTCCTTTTATCGGC
CATAACGCCTTTATGTTTGTCTTTATCTTTGCCCTGATTATGTTCACCTGGGGTGAACTATATTCCTTGTTCCCGGCCGT
CAACGCCGATATTTTCGGAACTACCTACGCCGCAACAAATTATGGTTTCATTTACAGTGCCAAGGGTTTGAGCGGTATTG
TTGGCGGCTTTGTGGCCGCCCTGGTGGCCCAGATGAGCGGCTGGACACCGGTATTTTTAACTGGTGCCGTAATGTCCCTG
CTGGCCGGTTTGGGTGCCCTTTTATTGCGGAGTATTCCTAAACCAGTCCCCTCAGGGATTAAGAGCGGAAGCAGTGGTTT
TTCCAGCCAGGCTTAA

Upstream 100 bases:

>100_bases
AATAGCCAATCTACCTCCCAAATATAGTCAGTAAATGCAAAAAAGATCGAAATAAATAACCTTAGGGGGTAAATTGCATT
TAATTTGGGAGGTGCTTATA

Downstream 100 bases:

>100_bases
TAATAAGTTGAGAGTTCCGCTATAAGCAGGGGTACCTGGTACCCCTGCTTATGCTAAAAGGAGGCATTAACCATGGAGCT
TCTGATAACTGGCGGGTCTG

Product: major facilitator transporter

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MSIQNPETPFGPREVPKPFFENKWVQLIIAMIGMIMIANLQYAWTLFVPEVVKGLNSTKAAVQMGFSLFIAFESWGQPIA
GYFMDRYSPRALLTVAALMIGIGWAGMGLVKSLGALYFLYSMAGVGAALIYSGSIASGVRWFEASKRGMASGLVAAAFGS
GAALFIPFIAIILKKQGYNSAFVTTGVIQGIIALIAAQFMRFPAKPKTSSSSTAKAQVSASQRDFTTVEMFKTAHFWIIY
LMFLFICTGGMIVTAQTKPFGTEAGIAASIIVTAATINTIANGAGRIIWGMISDKLGRYQTMFVAFTINAIAMALVPFIG
HNAFMFVFIFALIMFTWGELYSLFPAVNADIFGTTYAATNYGFIYSAKGLSGIVGGFVAALVAQMSGWTPVFLTGAVMSL
LAGLGALLLRSIPKPVPSGIKSGSSGFSSQA

Sequences:

>Translated_431_residues
MSIQNPETPFGPREVPKPFFENKWVQLIIAMIGMIMIANLQYAWTLFVPEVVKGLNSTKAAVQMGFSLFIAFESWGQPIA
GYFMDRYSPRALLTVAALMIGIGWAGMGLVKSLGALYFLYSMAGVGAALIYSGSIASGVRWFEASKRGMASGLVAAAFGS
GAALFIPFIAIILKKQGYNSAFVTTGVIQGIIALIAAQFMRFPAKPKTSSSSTAKAQVSASQRDFTTVEMFKTAHFWIIY
LMFLFICTGGMIVTAQTKPFGTEAGIAASIIVTAATINTIANGAGRIIWGMISDKLGRYQTMFVAFTINAIAMALVPFIG
HNAFMFVFIFALIMFTWGELYSLFPAVNADIFGTTYAATNYGFIYSAKGLSGIVGGFVAALVAQMSGWTPVFLTGAVMSL
LAGLGALLLRSIPKPVPSGIKSGSSGFSSQA
>Mature_430_residues
SIQNPETPFGPREVPKPFFENKWVQLIIAMIGMIMIANLQYAWTLFVPEVVKGLNSTKAAVQMGFSLFIAFESWGQPIAG
YFMDRYSPRALLTVAALMIGIGWAGMGLVKSLGALYFLYSMAGVGAALIYSGSIASGVRWFEASKRGMASGLVAAAFGSG
AALFIPFIAIILKKQGYNSAFVTTGVIQGIIALIAAQFMRFPAKPKTSSSSTAKAQVSASQRDFTTVEMFKTAHFWIIYL
MFLFICTGGMIVTAQTKPFGTEAGIAASIIVTAATINTIANGAGRIIWGMISDKLGRYQTMFVAFTINAIAMALVPFIGH
NAFMFVFIFALIMFTWGELYSLFPAVNADIFGTTYAATNYGFIYSAKGLSGIVGGFVAALVAQMSGWTPVFLTGAVMSLL
AGLGALLLRSIPKPVPSGIKSGSSGFSSQA

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Escherichia coli, GI1789969, Length=373, Percent_Identity=25.4691689008043, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI193209150, Length=366, Percent_Identity=22.4043715846995, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45921; Mature: 45790

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCC
>Mature Secondary Structure 
SIQNPETPFGPREVPKPFFENKWVQLIIAMIGMIMIANLQYAWTLFVPEVVKGLNSTKA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHH
AVQMGFSLFIAFESWGQPIAGYFMDRYSPRALLTVAALMIGIGWAGMGLVKSLGALYFLY
HHHHHHHHEEEEHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
SMAGVGAALIYSGSIASGVRWFEASKRGMASGLVAAAFGSGAALFIPFIAIILKKQGYNS
HHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
AFVTTGVIQGIIALIAAQFMRFPAKPKTSSSSTAKAQVSASQRDFTTVEMFKTAHFWIIY
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHH
LMFLFICTGGMIVTAQTKPFGTEAGIAASIIVTAATINTIANGAGRIIWGMISDKLGRYQ
HHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHCCHHH
TMFVAFTINAIAMALVPFIGHNAFMFVFIFALIMFTWGELYSLFPAVNADIFGTTYAATN
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHCCC
YGFIYSAKGLSGIVGGFVAALVAQMSGWTPVFLTGAVMSLLAGLGALLLRSIPKPVPSGI
CCEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
KSGSSGFSSQA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]