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The map label for this gene is fur [H]

Identifier: 83590262

GI number: 83590262

Start: 1459932

End: 1460354

Strand: Reverse

Name: fur [H]

Synonym: Moth_1415

Alternate gene names: 83590262

Gene position: 1460354-1459932 (Counterclockwise)

Preceding gene: 83590263

Following gene: 83590261

Centisome position: 55.55

GC content: 52.72

Gene sequence:

>423_bases
ATGGTCGCCGGGGTAGCCCTGGATCCGGAAAAGTTTAAAAAGAGCGAGCGGCGTTTAACCCCCCAGCGCCAGGCGGTGCT
TAAGGCCTTTCTGGAATTATCCCGGGAACACCCTACGGCCGAATCTATTTATCATGTAGCCCGGCGGTATTGCCCGACGG
TAGGGATGGCTACTGTCTATCGCTCCCTCGATCTCTTTGTCCAGATGGGTATTATTGTAAAGGCCCCGACCCTGAACGGG
ACGGCCCGTTATGAGATGAACCAAACCCCCCATAATCATTTTATCTGTCTCAAGTGCGGTCGTACCTACGAATTTCGCAG
GAGACAGGAACCCCTGGCGGAAAGGGAGATAGAAAAGGCCGGTTTTGAGGTTATCAGTGCTTCAATAATCTTCTTTGGCT
ATTGCCCCGCCTGTCGTGAATAG

Upstream 100 bases:

>100_bases
TTGCCGGAAGTTAAACTGCACTGCTCCAACCTGGGCGCCAGCGCCCTCCATGATGCAATCCGTAACTACCAGGCAAAAAT
GCAGGCGGGAGGGCAGCAAA

Downstream 100 bases:

>100_bases
ATTAGCCGCCTCCCTGGATTCAATCCTTTAAAATACCTCTTTGGCGGTAGAAAGCCCCCGTGACCCCGGAGAAACTCTCC
GGGGCTATTTTTATTACCGC

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MVAGVALDPEKFKKSERRLTPQRQAVLKAFLELSREHPTAESIYHVARRYCPTVGMATVYRSLDLFVQMGIIVKAPTLNG
TARYEMNQTPHNHFICLKCGRTYEFRRRQEPLAEREIEKAGFEVISASIIFFGYCPACRE

Sequences:

>Translated_140_residues
MVAGVALDPEKFKKSERRLTPQRQAVLKAFLELSREHPTAESIYHVARRYCPTVGMATVYRSLDLFVQMGIIVKAPTLNG
TARYEMNQTPHNHFICLKCGRTYEFRRRQEPLAEREIEKAGFEVISASIIFFGYCPACRE
>Mature_140_residues
MVAGVALDPEKFKKSERRLTPQRQAVLKAFLELSREHPTAESIYHVARRYCPTVGMATVYRSLDLFVQMGIIVKAPTLNG
TARYEMNQTPHNHFICLKCGRTYEFRRRQEPLAEREIEKAGFEVISASIIFFGYCPACRE

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates genes involved in iron scavenging or photosynthetic electron transport [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=133, Percent_Identity=32.3308270676692, Blast_Score=74, Evalue=2e-15,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16100; Mature: 16100

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAGVALDPEKFKKSERRLTPQRQAVLKAFLELSREHPTAESIYHVARRYCPTVGMATVY
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHH
RSLDLFVQMGIIVKAPTLNGTARYEMNQTPHNHFICLKCGRTYEFRRRQEPLAEREIEKA
HHHHHHHHHCEEEECCCCCCCEEEECCCCCCCCEEEEECCCCHHHHHHCCCHHHHHHHHH
GFEVISASIIFFGYCPACRE
HHHHHHHHHHEEECCCCCCC
>Mature Secondary Structure
MVAGVALDPEKFKKSERRLTPQRQAVLKAFLELSREHPTAESIYHVARRYCPTVGMATVY
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHH
RSLDLFVQMGIIVKAPTLNGTARYEMNQTPHNHFICLKCGRTYEFRRRQEPLAEREIEKA
HHHHHHHHHCEEEECCCCCCCEEEECCCCCCCCEEEEECCCCHHHHHHCCCHHHHHHHHH
GFEVISASIIFFGYCPACRE
HHHHHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704986 [H]