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The map label for this gene is malR

Identifier: 82751101

GI number: 82751101

Start: 1497589

End: 1498608

Strand: Reverse

Name: malR

Synonym: SAB1369c

Alternate gene names: 82751101

Gene position: 1498608-1497589 (Counterclockwise)

Preceding gene: 82751102

Following gene: 82751100

Centisome position: 54.64

GC content: 31.96

Gene sequence:

>1020_bases
ATGGTTACGATTAAAGATGTTGCACTAAAAGCCGGTGTTTCTCCTTCGACAGTTTCAAGAGTTATAAAAGGAAATCAACG
TATTAGCGAAGCGACAATTTCAAAAGTGAAGAAAGTTATGGAAGAATTGAATTATTTTCCTAATACTGCTGCTAGAACTT
TAATTACTAACCAAACATATAAAATTGGTTTAGTGTTAAAAGGGTCTGAGGAGCCTATTCGACTGAATCCATTCTACATC
AATGTATTGCTAGGGATTTCTGAAACGTGCAACCAGCATGGCTATGGTACACAAACGACAGTCTCAAATAATATGAATGA
TTTAATGGATGAAGTTTATAAAATGATTAAACAACGAATGGTTGATGCGTTTATACTGCTCTATTCAAAAGAAAATGATC
CGATTAAACAAATGTTAATTGATGAAAACATGCCATTTATTGTGATTGGTAAGCCTACATCGGATATAGATCATCAATTT
ACACACATAGATAATGATAATATATTAGCTTCTGAAAATTTGACACGACATGTTATTGAACAAGGTGTAGATGAATTAAT
ATTTATTACAGAAAAAGGCGATTTTGAAGTTTCGAAAGACAGGATTCAAGGATTTGAAACGATAGCTTCTCAAAATAAAA
TTAATTATCAAATTATTGAGACTAGTAATGAAAGAGAAGTTATTTTTAATTACATGCAAAATCTACATACGCGTTTGAAG
GACCCAAATATTAAACAGGCAATCATTTCGTTAGATGCTATGTTACATTTAGCGATTTTAAGCGTCCTATATGAACTTAA
TATTGAAATTCCGAAAGATGTAATGACAGCAACGTTCAATGATTCTTATTTAACCGAAATTGCGTCACCACCTCAAACCA
GTATTGACATCAAGCCTCGAATGTTAGGTCAACAGGCTGGTGCAGCAATTTTAAATATATTAAAAAACAAAGCACAGGAT
GTTATTGAACTCGTCATTATAGATACAGAATTGAAAATAAGAAAATCAACACAACGATAG

Upstream 100 bases:

>100_bases
TTGCACAAATCTTTTGACTTTTTTAGAAAGTGTGACTAAACTGGTATTATACAGAGGTTGGAAGCGTTTTCCAATACAGA
GATTAACAGGAGGTGATTAA

Downstream 100 bases:

>100_bases
CACAGGAGTTTTAAAATGAATAAGCAATGGTGGAAAGAAGCAGTAGCATATCAAGTATATCCAAGAAGTTTTAATGATAG
TAATCACGATGGTATTGGGG

Product: maltose operon transcriptional repressor

Products: NA

Alternate protein names: Maltose operon transcriptional repressor [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MVTIKDVALKAGVSPSTVSRVIKGNQRISEATISKVKKVMEELNYFPNTAARTLITNQTYKIGLVLKGSEEPIRLNPFYI
NVLLGISETCNQHGYGTQTTVSNNMNDLMDEVYKMIKQRMVDAFILLYSKENDPIKQMLIDENMPFIVIGKPTSDIDHQF
THIDNDNILASENLTRHVIEQGVDELIFITEKGDFEVSKDRIQGFETIASQNKINYQIIETSNEREVIFNYMQNLHTRLK
DPNIKQAIISLDAMLHLAILSVLYELNIEIPKDVMTATFNDSYLTEIASPPQTSIDIKPRMLGQQAGAAILNILKNKAQD
VIELVIIDTELKIRKSTQR

Sequences:

>Translated_339_residues
MVTIKDVALKAGVSPSTVSRVIKGNQRISEATISKVKKVMEELNYFPNTAARTLITNQTYKIGLVLKGSEEPIRLNPFYI
NVLLGISETCNQHGYGTQTTVSNNMNDLMDEVYKMIKQRMVDAFILLYSKENDPIKQMLIDENMPFIVIGKPTSDIDHQF
THIDNDNILASENLTRHVIEQGVDELIFITEKGDFEVSKDRIQGFETIASQNKINYQIIETSNEREVIFNYMQNLHTRLK
DPNIKQAIISLDAMLHLAILSVLYELNIEIPKDVMTATFNDSYLTEIASPPQTSIDIKPRMLGQQAGAAILNILKNKAQD
VIELVIIDTELKIRKSTQR
>Mature_339_residues
MVTIKDVALKAGVSPSTVSRVIKGNQRISEATISKVKKVMEELNYFPNTAARTLITNQTYKIGLVLKGSEEPIRLNPFYI
NVLLGISETCNQHGYGTQTTVSNNMNDLMDEVYKMIKQRMVDAFILLYSKENDPIKQMLIDENMPFIVIGKPTSDIDHQF
THIDNDNILASENLTRHVIEQGVDELIFITEKGDFEVSKDRIQGFETIASQNKINYQIIETSNEREVIFNYMQNLHTRLK
DPNIKQAIISLDAMLHLAILSVLYELNIEIPKDVMTATFNDSYLTEIASPPQTSIDIKPRMLGQQAGAAILNILKNKAQD
VIELVIIDTELKIRKSTQR

Specific function: Transcriptional repressor of the malA gene for maltase [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=311, Percent_Identity=27.6527331189711, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787580, Length=321, Percent_Identity=28.6604361370716, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787948, Length=327, Percent_Identity=26.2996941896024, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790369, Length=343, Percent_Identity=26.2390670553936, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1787906, Length=207, Percent_Identity=27.0531400966184, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786268, Length=309, Percent_Identity=25.8899676375405, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789202, Length=308, Percent_Identity=24.3506493506494, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790715, Length=326, Percent_Identity=24.2331288343558, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1789068, Length=302, Percent_Identity=22.5165562913907, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789456, Length=352, Percent_Identity=25, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786540, Length=324, Percent_Identity=24.0740740740741, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI48994940, Length=304, Percent_Identity=22.6973684210526, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788474, Length=211, Percent_Identity=26.5402843601896, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38403; Mature: 38403

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTIKDVALKAGVSPSTVSRVIKGNQRISEATISKVKKVMEELNYFPNTAARTLITNQTY
CEEEHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHEEECCEE
KIGLVLKGSEEPIRLNPFYINVLLGISETCNQHGYGTQTTVSNNMNDLMDEVYKMIKQRM
EEEEEEECCCCCEEECCEEEEEEECCHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHH
VDAFILLYSKENDPIKQMLIDENMPFIVIGKPTSDIDHQFTHIDNDNILASENLTRHVIE
HHHHEEEEECCCCHHHHHHHCCCCCEEEEECCCCCCCCHHEEECCCCEEECCHHHHHHHH
QGVDELIFITEKGDFEVSKDRIQGFETIASQNKINYQIIETSNEREVIFNYMQNLHTRLK
CCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCC
DPNIKQAIISLDAMLHLAILSVLYELNIEIPKDVMTATFNDSYLTEIASPPQTSIDIKPR
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEECCCHHHHHHCCCCCCCCCCCHH
MLGQQAGAAILNILKNKAQDVIELVIIDTELKIRKSTQR
HHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECCCCCC
>Mature Secondary Structure
MVTIKDVALKAGVSPSTVSRVIKGNQRISEATISKVKKVMEELNYFPNTAARTLITNQTY
CEEEHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHEEECCEE
KIGLVLKGSEEPIRLNPFYINVLLGISETCNQHGYGTQTTVSNNMNDLMDEVYKMIKQRM
EEEEEEECCCCCEEECCEEEEEEECCHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHH
VDAFILLYSKENDPIKQMLIDENMPFIVIGKPTSDIDHQFTHIDNDNILASENLTRHVIE
HHHHEEEEECCCCHHHHHHHCCCCCEEEEECCCCCCCCHHEEECCCCEEECCHHHHHHHH
QGVDELIFITEKGDFEVSKDRIQGFETIASQNKINYQIIETSNEREVIFNYMQNLHTRLK
CCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCC
DPNIKQAIISLDAMLHLAILSVLYELNIEIPKDVMTATFNDSYLTEIASPPQTSIDIKPR
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEECCCHHHHHHCCCCCCCCCCCHH
MLGQQAGAAILNILKNKAQDVIELVIIDTELKIRKSTQR
HHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7730272 [H]