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The map label for this gene is rnz [H]

Identifier: 82751097

GI number: 82751097

Start: 1492028

End: 1492948

Strand: Reverse

Name: rnz [H]

Synonym: SAB1365c

Alternate gene names: 82751097

Gene position: 1492948-1492028 (Counterclockwise)

Preceding gene: 82751100

Following gene: 82751095

Centisome position: 54.44

GC content: 33.33

Gene sequence:

>921_bases
ATGGAAGTTACATTTTTTGGAACGAGTGCAGGTTTGCCTACAAAAGAGAGAAATACACAAGCAATCGCCTTAAATTTAGA
ACCATATTCCAATTCCATATGGCTTTTCGACGTTGGTGAAGGTACACAGCACCAAATTTTACATCATGCAATTAAATTAG
GAAAAGTGACACATATATTTATTACTCATATGCATGGCGATCATATTTTCGGTTTGCCAGGATTACTTTCTAGTCGTTCT
TTTCAGGGTGGTGAACAAAAGCCGCTTACATTAGTTGGACCAAAAGGAATTAAAGCATATGTGGAAATGTCTATGAATTT
ATCAGAGTCACATTTAAACTATCCAATTACATATATTGAAATCGATGATCATCTAACATATCATCATGATGGTTTTACTG
TAGAGGCGCATTTACTTAATCATGGTATTCCATCATATGGATATAGAGTAATGGCACCTGAAACTACAGGTACAATCAAT
GTTGAAGCGTTAAAAAACATTGGTCTTGAACCAGGTCCTAAATATCAAGAAGTAAAATCTCATGATACATTTGAACATAA
TGGTCAAGTTTATCAATCAAAAGATTTTAGAGGTGAGTCCAAACAGGGTCCAATTGTAGCAATTTTTGGTGATACAAAAC
CATGTTCTAATGAACGTGTGATTTCTAGAGATGCTGATGTGATGGTACATGAAGCGACCTATATAGATGGTGAAAAGCAT
TTAGCCAACAATTATCATCATAGCCATATTGAAGACGTATTTGCATTGATAAAAGAAGCCAATGTTAAACGTACGTTGAT
TACACATTTGAGCAATCGCTATAATACAGAAGATATAAATGAAATTTATCAAACATTGATACAAAATGAGGATACGCCGA
ATTTTAATTTTGTGAAAGATTTTGATAGTTTTAAAATCTAA

Upstream 100 bases:

>100_bases
GCAAAGATGAATTTTTAACAGATTTTGATTCAAGTATAAATTAAAACTAAATTGATACAAATTTTATGATAAAATGAATT
GAAGAAAAGGAGGGGCATAT

Downstream 100 bases:

>100_bases
TGACAAAGTAATAAACAATGCTTGCCAAATAGTAATAATTTATAAAAATAACCCGTCAAACACAGTGCTTGCGATGATGC
ATACATGTGTTGGCGGGTTT

Product: metallo-beta-lactamase

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIFITHMHGDHIFGLPGLLSSRS
FQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIEIDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTIN
VEALKNIGLEPGPKYQEVKSHDTFEHNGQVYQSKDFRGESKQGPIVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKH
LANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQTLIQNEDTPNFNFVKDFDSFKI

Sequences:

>Translated_306_residues
MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIFITHMHGDHIFGLPGLLSSRS
FQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIEIDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTIN
VEALKNIGLEPGPKYQEVKSHDTFEHNGQVYQSKDFRGESKQGPIVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKH
LANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQTLIQNEDTPNFNFVKDFDSFKI
>Mature_306_residues
MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIFITHMHGDHIFGLPGLLSSRS
FQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIEIDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTIN
VEALKNIGLEPGPKYQEVKSHDTFEHNGQVYQSKDFRGESKQGPIVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKH
LANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQTLIQNEDTPNFNFVKDFDSFKI

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

Organism=Homo sapiens, GI8922122, Length=355, Percent_Identity=29.8591549295775, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI260166619, Length=283, Percent_Identity=25.7950530035336, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI145553959, Length=283, Percent_Identity=25.7950530035336, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI260166622, Length=283, Percent_Identity=25.7950530035336, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI87082078, Length=308, Percent_Identity=41.2337662337662, Blast_Score=239, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 34599; Mature: 34599

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIF
CEEEEEECCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEE
ITHMHGDHIFGLPGLLSSRSFQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIE
EEEECCCEEECCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCHHHCCCCEEEEE
IDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTINVEALKNIGLEPGPKYQEVKS
ECCCEEEECCCEEEEEEEHHCCCCCCCEEEECCCCCCEEEHHHHHHCCCCCCCCHHHHCC
HDTFEHNGQVYQSKDFRGESKQGPIVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKH
CCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCEEEEEEEEECCHHH
LANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQTLIQNEDTPNFNFVKD
HHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEEC
FDSFKI
CCCCCC
>Mature Secondary Structure
MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIF
CEEEEEECCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEE
ITHMHGDHIFGLPGLLSSRSFQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIE
EEEECCCEEECCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCHHHCCCCEEEEE
IDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTINVEALKNIGLEPGPKYQEVKS
ECCCEEEECCCEEEEEEEHHCCCCCCCEEEECCCCCCEEEHHHHHHCCCCCCCCHHHHCC
HDTFEHNGQVYQSKDFRGESKQGPIVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKH
CCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCEEEEEEEEECCHHH
LANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQTLIQNEDTPNFNFVKD
HHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEEC
FDSFKI
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA