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The map label for this gene is fur

Identifier: 82751091

GI number: 82751091

Start: 1487645

End: 1488094

Strand: Reverse

Name: fur

Synonym: SAB1359c

Alternate gene names: 82751091

Gene position: 1488094-1487645 (Counterclockwise)

Preceding gene: 82751092

Following gene: 82751090

Centisome position: 54.26

GC content: 36.44

Gene sequence:

>450_bases
TTGGAAGAACGATTAAATCGCGTTAAGCAACAATTACAACAATCATCATATAAGCTAACGCCACAACGCGAAGCTACTGT
TAGAGTTCTAATTGAAAATGAAAAAGATCATCTAAGTGCTGAAGACGTATATCTGAAAGTAAAAGACAAAGCGCCTGAAA
TTGGCTTGGCGACAGTATACAGAACGTTAGAGTTGTTAGCTGAACTAAAAGTTGTCGACAAAATTAACTTTGGTGATGGC
GTCGCTCGTTTTGATTTAAGAAAAGAAGGCGCAAAACATTTCCACCATCATTTAGTATGCATGGAATGTGGTCGTGTAGA
TGAAATCGATGAAGATTTGTTACCAGAAGTTGAAAATCGAGTTGAAAATGAGTTCAATTTTAAAATTTTAGATCATCGTT
TAACTTTCCATGGTGTGTGTGAAACGTGCCAAGCTAAAGGTAAAGGATAG

Upstream 100 bases:

>100_bases
TGAGAAAAGCTTGCATTTTATTGAGAAAACTGTTAGTTTTAATTGTGAAGTTTGAAATAATTTGTAATGATTTTAATTAT
TAGTAGGGGAGTGGACATCG

Downstream 100 bases:

>100_bases
TAAATTGCGTAGGTTAAATTAACCTTCGCTTTTTTTAGAGGTGTGGTTATGGAAACAATTATTGAAGAATATTTGCGTTT
TATACAAATTGAAAAAGGAC

Product: iron transcriptional regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MEERLNRVKQQLQQSSYKLTPQREATVRVLIENEKDHLSAEDVYLKVKDKAPEIGLATVYRTLELLAELKVVDKINFGDG
VARFDLRKEGAKHFHHHLVCMECGRVDEIDEDLLPEVENRVENEFNFKILDHRLTFHGVCETCQAKGKG

Sequences:

>Translated_149_residues
MEERLNRVKQQLQQSSYKLTPQREATVRVLIENEKDHLSAEDVYLKVKDKAPEIGLATVYRTLELLAELKVVDKINFGDG
VARFDLRKEGAKHFHHHLVCMECGRVDEIDEDLLPEVENRVENEFNFKILDHRLTFHGVCETCQAKGKG
>Mature_149_residues
MEERLNRVKQQLQQSSYKLTPQREATVRVLIENEKDHLSAEDVYLKVKDKAPEIGLATVYRTLELLAELKVVDKINFGDG
VARFDLRKEGAKHFHHHLVCMECGRVDEIDEDLLPEVENRVENEFNFKILDHRLTFHGVCETCQAKGKG

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=129, Percent_Identity=34.1085271317829, Blast_Score=84, Evalue=4e-18,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17244; Mature: 17244

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEERLNRVKQQLQQSSYKLTPQREATVRVLIENEKDHLSAEDVYLKVKDKAPEIGLATVY
CHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHH
RTLELLAELKVVDKINFGDGVARFDLRKEGAKHFHHHLVCMECGRVDEIDEDLLPEVENR
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
VENEFNFKILDHRLTFHGVCETCQAKGKG
HCCCCCEEEEECHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEERLNRVKQQLQQSSYKLTPQREATVRVLIENEKDHLSAEDVYLKVKDKAPEIGLATVY
CHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHH
RTLELLAELKVVDKINFGDGVARFDLRKEGAKHFHHHLVCMECGRVDEIDEDLLPEVENR
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
VENEFNFKILDHRLTFHGVCETCQAKGKG
HCCCCCEEEEECHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]