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The map label for this gene is aroA

Identifier: 82751063

GI number: 82751063

Start: 1456227

End: 1457525

Strand: Reverse

Name: aroA

Synonym: SAB1328c

Alternate gene names: 82751063

Gene position: 1457525-1456227 (Counterclockwise)

Preceding gene: 82751064

Following gene: 82751062

Centisome position: 53.15

GC content: 36.49

Gene sequence:

>1299_bases
ATGGTAAATGAACAAATCATTGATATTTCAGGTCCGTTAAAGGGCGAAATAGAAGTGCCGGGCGATAAATCAATGACACA
CCGTGCAATCATGTTGGCGTCGCTAGCTGAAGGTGTATCTACTATATATAAGCCACTACTTGGCGAAGATTGTCGTCGTA
CGATGGACATTTTCCGACTGTTAGGTGTAGAAATCAAAGAAGATGATGAAAAATTAGTTGTGACTTCCCCAGGATATCAA
TCTTTTAACACGCCACATCAAGTATTGTATACAGGTAATTCTGGTACGACAACACGATTATTGGCAGGTTTGTTAAGTGG
TTTAGGTATTGAAAGTGTCTTGTCTGGAGATGTTTCCATAGGTAAAAGGCCGATGGATCGTGTTTTAAGACCGTTAAAAA
GTATGAATGCAAATATTGAAGGAATTGAAGACAATTACACCCCATTAATCATTAAACCATCTGTAATTAAAGGTATTAAT
TACAAGATGGAAGTGGCAAGTGCACAAGTGAAAAGTGCCATCTTATTCGCAAGTCTATTTTCTAAGGAAGCGACCATCAT
TAAAGAATTAGATGTAAGTCGAAATCATACTGAGACGATGTTCAGACATTTTAATATTCCAATTGAAGCAGAAGGGTTGT
CAATTACTACAACTCCTGAAGCAATTCGATACATTAAACCTGCAGATTTTCATGTTCCTGGCGATATTTCATCTGCAGCG
TTCTTTATTGTTGCAGCACTTATCACACCAGGAAGTGATGTAACAATTCATAATGTTGGAATCAATCCAACACGTTCAGG
TATTATTGATATTGTTGAAAAAATGGGCGGTAATATTCAACTTTTCAATCAAACAACTGGTGCTGAACCCACTGCTTCTA
TTCGTATTCAATACACACCAATGCTTCAACCAATAACAATCGAAGGAGAATTAGTGCCAAAAGCAATTGATGAACTGCCA
GTGATAGCATTACTTTGTACACAAGCAGTTGGCACGAGTACAATTAAAGATGCCGAGGAATTAAAAGTAAAAGAAACAAA
TAGAATTGATACAACGGCTGATATGTTAAACTTGTTAGGGTTTGAATTACAACCAACTAATGATGGATTGATTATTCATC
CGTCAGAATTTAAAACAAATGCAACAGTGGATAGTTTAACGGATCATCGAATAGGGATGATGCTTGCAGTTGCTTCTCTA
CTTTCAAGCGAACCTGTCAAAATCAAACAATTTGATGCTGTAAATGTATCATTTCCAGGATTTTTACCAAAACTAAAGCT
TTTAGAAAATGAGGGATAA

Upstream 100 bases:

>100_bases
GATTAGACAATTTGGAGATATCGTTGTACAACATGTTGATCAACTAACATTACAACATGCATGTGAACAATTAAAAACAT
ATTTTAAGTAGGTGAATGAA

Downstream 100 bases:

>100_bases
TATAAAATGGAAGATATCTATAAATTAATAGACGATATCAATCTACAAAAACTAGAAAATTTAGACTCTCGTGTTAATGA
AGCAATAACTACTGACAACG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MVNEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGVSTIYKPLLGEDCRRTMDIFRLLGVEIKEDDEKLVVTSPGYQ
SFNTPHQVLYTGNSGTTTRLLAGLLSGLGIESVLSGDVSIGKRPMDRVLRPLKSMNANIEGIEDNYTPLIIKPSVIKGIN
YKMEVASAQVKSAILFASLFSKEATIIKELDVSRNHTETMFRHFNIPIEAEGLSITTTPEAIRYIKPADFHVPGDISSAA
FFIVAALITPGSDVTIHNVGINPTRSGIIDIVEKMGGNIQLFNQTTGAEPTASIRIQYTPMLQPITIEGELVPKAIDELP
VIALLCTQAVGTSTIKDAEELKVKETNRIDTTADMLNLLGFELQPTNDGLIIHPSEFKTNATVDSLTDHRIGMMLAVASL
LSSEPVKIKQFDAVNVSFPGFLPKLKLLENEG

Sequences:

>Translated_432_residues
MVNEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGVSTIYKPLLGEDCRRTMDIFRLLGVEIKEDDEKLVVTSPGYQ
SFNTPHQVLYTGNSGTTTRLLAGLLSGLGIESVLSGDVSIGKRPMDRVLRPLKSMNANIEGIEDNYTPLIIKPSVIKGIN
YKMEVASAQVKSAILFASLFSKEATIIKELDVSRNHTETMFRHFNIPIEAEGLSITTTPEAIRYIKPADFHVPGDISSAA
FFIVAALITPGSDVTIHNVGINPTRSGIIDIVEKMGGNIQLFNQTTGAEPTASIRIQYTPMLQPITIEGELVPKAIDELP
VIALLCTQAVGTSTIKDAEELKVKETNRIDTTADMLNLLGFELQPTNDGLIIHPSEFKTNATVDSLTDHRIGMMLAVASL
LSSEPVKIKQFDAVNVSFPGFLPKLKLLENEG
>Mature_432_residues
MVNEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGVSTIYKPLLGEDCRRTMDIFRLLGVEIKEDDEKLVVTSPGYQ
SFNTPHQVLYTGNSGTTTRLLAGLLSGLGIESVLSGDVSIGKRPMDRVLRPLKSMNANIEGIEDNYTPLIIKPSVIKGIN
YKMEVASAQVKSAILFASLFSKEATIIKELDVSRNHTETMFRHFNIPIEAEGLSITTTPEAIRYIKPADFHVPGDISSAA
FFIVAALITPGSDVTIHNVGINPTRSGIIDIVEKMGGNIQLFNQTTGAEPTASIRIQYTPMLQPITIEGELVPKAIDELP
VIALLCTQAVGTSTIKDAEELKVKETNRIDTTADMLNLLGFELQPTNDGLIIHPSEFKTNATVDSLTDHRIGMMLAVASL
LSSEPVKIKQFDAVNVSFPGFLPKLKLLENEG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=428, Percent_Identity=27.5700934579439, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320332, Length=458, Percent_Identity=27.0742358078603, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46966; Mature: 46966

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGVSTIYKPLLGEDCRRTMDIFRL
CCCCEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LGVEIKEDDEKLVVTSPGYQSFNTPHQVLYTGNSGTTTRLLAGLLSGLGIESVLSGDVSI
HCCEEECCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHCCCCCC
GKRPMDRVLRPLKSMNANIEGIEDNYTPLIIKPSVIKGINYKMEVASAQVKSAILFASLF
CCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHCCCCEEEEHHHHHHHHHHHHHHHH
SKEATIIKELDVSRNHTETMFRHFNIPIEAEGLSITTTPEAIRYIKPADFHVPGDISSAA
CCCHHHHHHHCCCCCHHHHHHHHCCCCEEECCEEEEECHHHHHEECCCCCCCCCCCHHHH
FFIVAALITPGSDVTIHNVGINPTRSGIIDIVEKMGGNIQLFNQTTGAEPTASIRIQYTP
HHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEEEC
MLQPITIEGELVPKAIDELPVIALLCTQAVGTSTIKDAEELKVKETNRIDTTADMLNLLG
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHCCHHHHEECCCCCCCHHHHHHHHHC
FELQPTNDGLIIHPSEFKTNATVDSLTDHRIGMMLAVASLLSSEPVKIKQFDAVNVSFPG
CEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEEECCCC
FLPKLKLLENEG
CCCHHHHHCCCC
>Mature Secondary Structure
MVNEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGVSTIYKPLLGEDCRRTMDIFRL
CCCCEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LGVEIKEDDEKLVVTSPGYQSFNTPHQVLYTGNSGTTTRLLAGLLSGLGIESVLSGDVSI
HCCEEECCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHCCCCCC
GKRPMDRVLRPLKSMNANIEGIEDNYTPLIIKPSVIKGINYKMEVASAQVKSAILFASLF
CCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHCCCCEEEEHHHHHHHHHHHHHHHH
SKEATIIKELDVSRNHTETMFRHFNIPIEAEGLSITTTPEAIRYIKPADFHVPGDISSAA
CCCHHHHHHHCCCCCHHHHHHHHCCCCEEECCEEEEECHHHHHEECCCCCCCCCCCHHHH
FFIVAALITPGSDVTIHNVGINPTRSGIIDIVEKMGGNIQLFNQTTGAEPTASIRIQYTP
HHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEEEC
MLQPITIEGELVPKAIDELPVIALLCTQAVGTSTIKDAEELKVKETNRIDTTADMLNLLG
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHCCHHHHEECCCCCCCHHHHHHHHHC
FELQPTNDGLIIHPSEFKTNATVDSLTDHRIGMMLAVASLLSSEPVKIKQFDAVNVSFPG
CEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEEECCCC
FLPKLKLLENEG
CCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA