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The map label for this gene is prc [C]

Identifier: 82751011

GI number: 82751011

Start: 1393108

End: 1394598

Strand: Reverse

Name: prc [C]

Synonym: SAB1275c

Alternate gene names: 82751011

Gene position: 1394598-1393108 (Counterclockwise)

Preceding gene: 82751012

Following gene: 82751010

Centisome position: 50.85

GC content: 30.92

Gene sequence:

>1491_bases
ATGGATGATAAGCAACACACATCTTCATCCGATGATGAACGCGCTGAAATTGCAACAAGCAATCAAGACCAACAAACTAA
TTCATCGAAACGCGTTCACTTAAAACGTTGGCAATTCATATCAATTTTAATTGGTACAATCCTAATAACAGCTGTCATCA
CAGTTGTTGCATATATTTTTATAAATCAAAAAATAAATGGTTTAAACAAAACTGATCAAGCAAACTTAAATAAAATTGAA
AATGTGTATAAAATCTTAAATAGTGATTATTATAAAAAACAGAGCTCTGACAAGTTGAGTAAAGCTGCAATTGATGGCAT
GGTCAAAGAATTAAAAGATCCTTATTCTGAATATTTAACAAAAGAACAAACTAAATCCTTTAATGAAGGTGTTTCAGGTG
ATTTTGTAGGTATTGGTGCAGAAATGCAAAAGAAAAATGATCAAATTATGGTTACTAGCCCTATGAAGGGTTCTCCAGCA
GAACGTGCTGGCATCCGTCCTAAAGATGTCATTACTAAAGTAAATGGAAAATCAATTAAAGGTAAAGCATTAGATGAAGT
TGTCAAAGATGTTCGTGGTAAAGAAAACACTGAAGTAACTTTAACTGTTCAACGAGGCAGTGAAGAAAAAGACGTTAAGA
TTAAACGTGAAAAAATTCATGTTAAAAGTGTTGAGTATAAGAAAAAAGGTAAGGTTGGAGTTATTACTATTAATAAATTC
CAGAATGATACATCAGGTGAATTGAAAGATGCAGTTCTTAAAGCTCACAAAGATGGTTTGAAAAAGATTGTTTTAGATTT
AAGAAATAATCCAGGTGGACTACTAGATGAAGCTGTTAAAATGGCAAATATTTTTATCGATAAAGGAAAAACTGTTGTTA
AACTAGAAAAAGGTAAAGATACTGAAGCAATTCAAACTTCTAATGATGCGTTAAAGGAAGCGAAAGACATGGATATATCC
ATCTTAGTGAATGAAGGTTCAGCTAGCGCTTCTGAAGTGTTTACTGGTGCGCTAAAGGACTATAATAAAGCTAAAGTTTA
TGGGTCAAAAACATTCGGCAAAGGTGTCGTACAAACTACAAGAGAGTTTAAGGATGGTTCATTGTTAAAATATACTGAAA
TGAAATGGTTAACGCCAGATGGTCATTATATTCACGGTAAAGGCATTAAACCAGACGTTACTATTGACACACCTAAATAT
CAATCTTTAAATGTCATTCCTAATACAAAAACATTTAAAGTTGGAGACGATGATAAAAATATTAAAACTATTAAAATTGG
TTTATCAGCTTTAGGTTATAAAGTTGATAATGAATCAACGCAATTTGATCAAGCTTTAGAAAATCAGGTTAAAGCTTTCC
AACAAACGAATAAACTCGAGGTAACTGGTGAATTTAATAAAGAAACGAATAATAAATTTACTGAGTTATTAGTTGAAAAA
GCTAATAAACATGATGATGTTCTCGATAAATTGATTAATATTTTAAAATAA

Upstream 100 bases:

>100_bases
AATCAATTATAGAGAAATATGGTGCGCTATCTTGCATAAATTGATATGATTAACTACACAGAATTTAAAAGTACATAATA
CATAATAAGGAAGTGATACA

Downstream 100 bases:

>100_bases
GCGATACACACTGCTAAAATTGTATTATTATTATGTTAATGACACGCTTCCTAAATTTGCAAAGATAGCAATTTAGGAGG
CGTGTTTATTTTTATTGACG

Product: carboxy-terminal processing proteinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MDDKQHTSSSDDERAEIATSNQDQQTNSSKRVHLKRWQFISILIGTILITAVITVVAYIFINQKINGLNKTDQANLNKIE
NVYKILNSDYYKKQSSDKLSKAAIDGMVKELKDPYSEYLTKEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPA
ERAGIRPKDVITKVNGKSIKGKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVEYKKKGKVGVITINKF
QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKDTEAIQTSNDALKEAKDMDIS
ILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTTREFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKY
QSLNVIPNTKTFKVGDDDKNIKTIKIGLSALGYKVDNESTQFDQALENQVKAFQQTNKLEVTGEFNKETNNKFTELLVEK
ANKHDDVLDKLINILK

Sequences:

>Translated_496_residues
MDDKQHTSSSDDERAEIATSNQDQQTNSSKRVHLKRWQFISILIGTILITAVITVVAYIFINQKINGLNKTDQANLNKIE
NVYKILNSDYYKKQSSDKLSKAAIDGMVKELKDPYSEYLTKEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPA
ERAGIRPKDVITKVNGKSIKGKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVEYKKKGKVGVITINKF
QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKDTEAIQTSNDALKEAKDMDIS
ILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTTREFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKY
QSLNVIPNTKTFKVGDDDKNIKTIKIGLSALGYKVDNESTQFDQALENQVKAFQQTNKLEVTGEFNKETNNKFTELLVEK
ANKHDDVLDKLINILK
>Mature_496_residues
MDDKQHTSSSDDERAEIATSNQDQQTNSSKRVHLKRWQFISILIGTILITAVITVVAYIFINQKINGLNKTDQANLNKIE
NVYKILNSDYYKKQSSDKLSKAAIDGMVKELKDPYSEYLTKEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPA
ERAGIRPKDVITKVNGKSIKGKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVEYKKKGKVGVITINKF
QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKDTEAIQTSNDALKEAKDMDIS
ILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTTREFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKY
QSLNVIPNTKTFKVGDDDKNIKTIKIGLSALGYKVDNESTQFDQALENQVKAFQQTNKLEVTGEFNKETNNKFTELLVEK
ANKHDDVLDKLINILK

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain

Homologues:

Organism=Escherichia coli, GI1788134, Length=365, Percent_Identity=30.958904109589, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTPAL_STAAB (Q2YXZ9)

Other databases:

- EMBL:   AJ938182
- RefSeq:   YP_416752.1
- ProteinModelPortal:   Q2YXZ9
- STRING:   Q2YXZ9
- EnsemblBacteria:   EBSTAT00000012691
- GeneID:   3793436
- GenomeReviews:   AJ938182_GR
- KEGG:   sab:SAB1275c
- NMPDR:   fig|273036.3.peg.835
- eggNOG:   COG0793
- GeneTree:   EBGT00050000024165
- HOGENOM:   HBG750030
- OMA:   VESIFAF
- PhylomeDB:   Q2YXZ9
- ProtClustDB:   CLSK885341
- BioCyc:   SAUR273036:SAB1275C-MONOMER
- GO:   GO:0006508
- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477
- Gene3D:   G3DSA:1.10.101.10
- SMART:   SM00228
- SMART:   SM00245
- TIGRFAMs:   TIGR00225

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1; SSF50156 PDZ; SSF47090 PGBD_like

EC number: 3.4.21.102 [C]

Molecular weight: Translated: 55290; Mature: 55290

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50106 PDZ

Important sites: ACT_SITE 329-329 ACT_SITE 340-340 ACT_SITE 354-354

Signals:

None

Transmembrane regions:

HASH(0x185d5418)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDKQHTSSSDDERAEIATSNQDQQTNSSKRVHLKRWQFISILIGTILITAVITVVAYIF
CCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
INQKINGLNKTDQANLNKIENVYKILNSDYYKKQSSDKLSKAAIDGMVKELKDPYSEYLT
HHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIK
HHHHHHHHCCCCCCEEEECCHHHCCCCEEEEECCCCCCCHHHCCCCHHHHHEECCCCCCC
GKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVEYKKKGKVGVITINKF
CHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEHHEEEEEEECHHCCCCEEEEEEECC
QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKD
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCEEEEEECCCC
TEAIQTSNDALKEAKDMDISILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTT
CCHHCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCHHEEECCCCCCCHHHHHH
REFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKYQSLNVIPNTKTFKVGDDDKN
HHCCCCCEEEEECEEEECCCCCEEECCCCCCCEEECCCCCCEEEECCCCEEEEECCCCCC
IKTIKIGLSALGYKVDNESTQFDQALENQVKAFQQTNKLEVTGEFNKETNNKFTELLVEK
EEEEEEEHHHHCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHH
ANKHDDVLDKLINILK
CCCHHHHHHHHHHHHH
>Mature Secondary Structure
MDDKQHTSSSDDERAEIATSNQDQQTNSSKRVHLKRWQFISILIGTILITAVITVVAYIF
CCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
INQKINGLNKTDQANLNKIENVYKILNSDYYKKQSSDKLSKAAIDGMVKELKDPYSEYLT
HHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIK
HHHHHHHHCCCCCCEEEECCHHHCCCCEEEEECCCCCCCHHHCCCCHHHHHEECCCCCCC
GKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVEYKKKGKVGVITINKF
CHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEHHEEEEEEECHHCCCCEEEEEEECC
QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKD
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCEEEEEECCCC
TEAIQTSNDALKEAKDMDISILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTT
CCHHCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCHHEEECCCCCCCHHHHHH
REFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKYQSLNVIPNTKTFKVGDDDKN
HHCCCCCEEEEECEEEECCCCCEEECCCCCCCEEECCCCCCEEEECCCCEEEEECCCCCC
IKTIKIGLSALGYKVDNESTQFDQALENQVKAFQQTNKLEVTGEFNKETNNKFTELLVEK
EEEEEEEHHHHCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHH
ANKHDDVLDKLINILK
CCCHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Cleavage of the C-terminal peptide from the precursor form of penicillin-binding protein 3 [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA