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The map label for this gene is setC [H]

Identifier: 82750375

GI number: 82750375

Start: 689654

End: 690874

Strand: Direct

Name: setC [H]

Synonym: SAB0622

Alternate gene names: 82750375

Gene position: 689654-690874 (Clockwise)

Preceding gene: 82750374

Following gene: 82750376

Centisome position: 25.15

GC content: 32.19

Gene sequence:

>1221_bases
ATGGATATGTTTGCAGCGTTATTACAAATAAAGAATTATAAACTCTTTGTTGCTAATATGTTTCTACTAGGTATGGGTAT
TGCGGTTACAGTCCCATATCTTGTTCTTTTTGCAACTAAAGATTTAGGTATGACAACAAATCAGTATGGATTACTTCTAG
CATCTGCAGCGATTAGCCAGTTTACAGTAAATTCAATTATTGCTAGATTTTCGGATACGCATCACTTTAATAGAAAAATT
ATTATTATTCTCGCATTATTAATGGGTTCGCTTGGTTTTTCAATATACTTTTTTGTAGATACAATCTGGTTATTCATATT
ACTATATGCGATTTTCCAAGGATTATTTGCACCAGCAATGCCCCAACTTTACGCATCTGCTAGAGAATCTATCAATGTTT
CAAGCTCTAAAGATAGAGCTCAATTTGCCAACACAGTATTACGTTCAATGTTCTCATTGGGCTTTTTATTTGGTCCATTT
ATTGGTGCGCAATTAATCGGATTAAAAGGCTATGCTGGATTGTTTGGTGGAACAATAAGTATCATTTTATTTACTTTAGT
ACTTCAAGTGTTTTTCTATAAGGATTTAAACATTAAACAACCTATTAGTACGCAACAACATGTTGAAAAAATTGCTCCTA
ATATGTTTAAAGACAAAACGCTTTTATTACCATTTATTGCATTTATTTTATTACACATTGGACAATGGATGTATACGATG
AATATGCCTTTATTTGTTACTGATTATTTAAAAGAAAATGAGCAACATGTCGGTTATTTAGCTAGTTTATGTGCTGGTTT
AGAAGTGCCATTTATGATCATTCTTGGCGTTTTATCATCTAGATTACAGACTCGAACATTGTTGATTTATGGAGCGATTT
TTGGTGGTTTATTCTACTTCAGCATAGGGGTATTTAAAAACTTCTATATGATGTTAGCAGGACAGGTGTTTTTAGCTATT
TTCTTAGCGGTTCTTTTAGGAATTGGTATTAGTTATTTCCAAGATATCTTAGCAGATTTTCCAGGATACGCCTCAACACT
TTTTTCTAATGCAATGGTTATTGGACAGTTAGGCGGTAACTTATTAGGTGGTGCTATGAGTCACTGGGTAGGTTTGGAAA
ATGTATTTTTTGTATCAGCAGCATCAATCATGTTAGGTATGATACTTATATTCTTTACTAAAAATCAAAAAATTACAAAA
GAGGATGTGATATCAACATGA

Upstream 100 bases:

>100_bases
TTAAACTATTCGGTTAAATTGAACGCAGTTGGTTGCTAATGCATCAACAGCAAAAGATCCCCTAATTAATAAATTAAAAG
GGGCTCTAAAAAGCGGGGTT

Downstream 100 bases:

>100_bases
CAATTATTTTATGGCTAATTATCATCGCTGCCTTCATGTTAGCATTTGTTGGGTTGATTAAGCCGGTTATTCCTTCTGTT
TTAGTGTTATGGGTTGGCTT

Product: sugar efflux transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MDMFAALLQIKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGMTTNQYGLLLASAAISQFTVNSIIARFSDTHHFNRKI
IIILALLMGSLGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQLYASARESINVSSSKDRAQFANTVLRSMFSLGFLFGPF
IGAQLIGLKGYAGLFGGTISIILFTLVLQVFFYKDLNIKQPISTQQHVEKIAPNMFKDKTLLLPFIAFILLHIGQWMYTM
NMPLFVTDYLKENEQHVGYLASLCAGLEVPFMIILGVLSSRLQTRTLLIYGAIFGGLFYFSIGVFKNFYMMLAGQVFLAI
FLAVLLGIGISYFQDILADFPGYASTLFSNAMVIGQLGGNLLGGAMSHWVGLENVFFVSAASIMLGMILIFFTKNQKITK
EDVIST

Sequences:

>Translated_406_residues
MDMFAALLQIKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGMTTNQYGLLLASAAISQFTVNSIIARFSDTHHFNRKI
IIILALLMGSLGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQLYASARESINVSSSKDRAQFANTVLRSMFSLGFLFGPF
IGAQLIGLKGYAGLFGGTISIILFTLVLQVFFYKDLNIKQPISTQQHVEKIAPNMFKDKTLLLPFIAFILLHIGQWMYTM
NMPLFVTDYLKENEQHVGYLASLCAGLEVPFMIILGVLSSRLQTRTLLIYGAIFGGLFYFSIGVFKNFYMMLAGQVFLAI
FLAVLLGIGISYFQDILADFPGYASTLFSNAMVIGQLGGNLLGGAMSHWVGLENVFFVSAASIMLGMILIFFTKNQKITK
EDVIST
>Mature_406_residues
MDMFAALLQIKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGMTTNQYGLLLASAAISQFTVNSIIARFSDTHHFNRKI
IIILALLMGSLGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQLYASARESINVSSSKDRAQFANTVLRSMFSLGFLFGPF
IGAQLIGLKGYAGLFGGTISIILFTLVLQVFFYKDLNIKQPISTQQHVEKIAPNMFKDKTLLLPFIAFILLHIGQWMYTM
NMPLFVTDYLKENEQHVGYLASLCAGLEVPFMIILGVLSSRLQTRTLLIYGAIFGGLFYFSIGVFKNFYMMLAGQVFLAI
FLAVLLGIGISYFQDILADFPGYASTLFSNAMVIGQLGGNLLGGAMSHWVGLENVFFVSAASIMLGMILIFFTKNQKITK
EDVIST

Specific function: Involved in the efflux of sugars. The physiological role may be the detoxification of non-metabolizable sugar analogs [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Set transporter family [H]

Homologues:

Organism=Escherichia coli, GI1790091, Length=376, Percent_Identity=26.8617021276596, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI48994875, Length=393, Percent_Identity=27.735368956743, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1788495, Length=351, Percent_Identity=27.3504273504274, Blast_Score=102, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004750 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45113; Mature: 45113

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503; 10209755; 10438463 [H]