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The map label for this gene is argS

Identifier: 82750314

GI number: 82750314

Start: 622800

End: 624461

Strand: Direct

Name: argS

Synonym: SAB0559

Alternate gene names: 82750314

Gene position: 622800-624461 (Clockwise)

Preceding gene: 82750313

Following gene: 82750315

Centisome position: 22.71

GC content: 33.09

Gene sequence:

>1662_bases
ATGAATATTATTGATCAAGTGAAACAAACATTAGTAGAAGAAATTGCAGCAAGTATTAACAAAGCAGGATTAGCAGATGA
GATTCCTGATATTAAAATTGAAGTTCCTAAAGATACAAAAAATGGAGATTATGCTACTAATATTGCGATGGTACTGACTA
AGATTGCAAAGCGTAATCCTCGTGAAATTGCTCAAGCGATTGTTGATAACTTAGATACTGAAAAAGCACATGTAAAACAA
ATTGACATTGCTGGTCCAGGATTCATTAATTTTTACTTAGATAATCAGTATTTAACAGCAATTATTCCTGAAGCAATTGA
AAAAGGTGATCAATTTGGATATGTAAATGAATCAAAAGGTCAAAATGTATTGCTTGAGTATGTTTCAGCTAACCCTACAG
GAGATTTACATATTGGTCATGCTAGAAATGCAGCAGTTGGTGATGCTTTAGCTAATATTTTAACTGCAGCTGGCTATAAT
GTAACACGTGAATATTATATTAATGATGCTGGTAATCAAATTACTAACTTAGCGCGTTCGATTGAAACACGTTTCTTTGA
AGCTTTAGGTGACAATAGTTATTCAATGCCAGAAGATGGCTATAATGGCAAAGATATTATTGAAATAGGTAAAGATTTAG
CAGAGAAACGCCCTGAAATTAAAGATTATTCTGAAGAAGCACGTTTGAAAGAATTTAGAAAATTAGGCGTAGAATACGAA
ATGGCTAAACTGAAAAATGATTTAGCAGAGTTCAATACGCATTTTGATAATTGGTTTAGTGAAACATCTTTATATGAAAA
AGGCGAAATTCTTGAAGTTTTAGCTAAAATGAAAGAATTAGGTTATACGTATGAAGCTGATGGCGCTACGTGGTTACGTA
CAACTGATTTTAAAGACGACAAAGACAGAGTATTAATTAAAAATGACGGTACATATACGTATTTCTTACCAGATATTGCG
TACCACTTCGATAAAGTTAAACGTGGTAATGACATTTTAATCGATTTATTTGGTGCTGATCATCATGGTTATATTAATCG
TTTGAAAGCATCTCTTGAAACGTTTGGTGTAGATAGTAATCGTTTAGAAATTCAAATCATGCAAATGGTTCGTTTAATGG
AAAATGGTAAAGAAGTGAAGATGAGTAAACGTACTGGTAATGCGATTACATTAAGAGAAATTATGGACGAAGTTGGAGTT
GACGCTGCACGTTATTTCTTAACTATGCGTAGTCCTGATAGTCACTTTGATTTTGATATGGAATTAGCGAAAGAGCAATC
TCAAGACAATCCAGTTTACTATGCTCAATATGCACATGCGCGTATTTGTTCAATTTTAAAACAAGCGAAAGAGCAAGGAA
TTGAGGTAGCTGCTGCGAATGATTTTACAACGATTACAAATGAAAAAGCGATTGAATTGTTGAAAAAAGTAGCTGATTTC
GAACCTACAATTGAAAGTGCTGCTGAGCATAGATCAGCACATAGAATTACTAATTATATTCAAGATTTAGCTTCTCATTT
CCATAAATTCTATAATGCTGAAAAAGTGTTAACAGATGATATTGAAAAAACAAAAGCACATGTTGCTATGATTGAAGCGG
TCAGAATTACATTGAAAAATGCATTGGCAATGGTCGGTGTAAGCGCACCTGAATCAATGTAA

Upstream 100 bases:

>100_bases
GTGGAGACGGTGGCAAGTTAAAGATTCATTATGAATTATATCAAGATAATGAAAAAATGGGTTCTTATCAATATGAAATT
AACTATAAGGAGATAGGCGA

Downstream 100 bases:

>100_bases
GAACATTTATATACACTCCAACGTAGAGTTTCTCGAAAGATACTTTGTGGGCTCTATGTCAAATTGGACTGATGCGTTCA
ATATCGGAAGTTAGGCAACT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQ
IDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGYVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYN
VTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKRPEIKDYSEEARLKEFRKLGVEYE
MAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIA
YHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGV
DAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVAAANDFTTITNEKAIELLKKVADF
EPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM

Sequences:

>Translated_553_residues
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQ
IDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGYVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYN
VTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKRPEIKDYSEEARLKEFRKLGVEYE
MAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIA
YHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGV
DAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVAAANDFTTITNEKAIELLKKVADF
EPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>Mature_553_residues
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQ
IDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGYVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYN
VTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKRPEIKDYSEEARLKEFRKLGVEYE
MAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIA
YHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGV
DAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVAAANDFTTITNEKAIELLKKVADF
EPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=619, Percent_Identity=23.5864297253635, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI197100773, Length=517, Percent_Identity=20.889748549323, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1788184, Length=592, Percent_Identity=25.6756756756757, Blast_Score=144, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71985061, Length=618, Percent_Identity=22.3300970873786, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71985068, Length=573, Percent_Identity=22.6876090750436, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320548, Length=614, Percent_Identity=22.1498371335505, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321883, Length=569, Percent_Identity=22.3198594024605, Blast_Score=104, Evalue=4e-23,
Organism=Drosophila melanogaster, GI28571570, Length=609, Percent_Identity=22.3316912972085, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI18859963, Length=608, Percent_Identity=21.7105263157895, Blast_Score=92, Evalue=1e-18,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 62397; Mature: 62397

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNP
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCH
REIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGYVNESKG
HHHHHHHHHCCCCCCHHHEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCC
QNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARS
CEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHH
IETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKRPEIKDYSEEARLKEFRKLGVEYE
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHH
MAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDD
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCC
KDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSN
CCEEEEEECCEEEEEHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCC
RLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDM
CHHHHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHHHCCCHHHHEEEECCCCCCCCCCH
ELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVAAANDFTTITNEKAIELLKKVADF
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCC
EPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAMVGVSAPESM
HHHHHCCCCCCCC
>Mature Secondary Structure
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNP
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCH
REIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGYVNESKG
HHHHHHHHHCCCCCCHHHEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCC
QNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARS
CEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHH
IETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKRPEIKDYSEEARLKEFRKLGVEYE
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHH
MAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDD
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCC
KDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSN
CCEEEEEECCEEEEEHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCC
RLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDM
CHHHHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHHHCCCHHHHEEEECCCCCCCCCCH
ELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVAAANDFTTITNEKAIELLKKVADF
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCC
EPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAMVGVSAPESM
HHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA