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The map label for this gene is yfnA [H]

Identifier: 82750289

GI number: 82750289

Start: 598025

End: 599509

Strand: Direct

Name: yfnA [H]

Synonym: SAB0534

Alternate gene names: 82750289

Gene position: 598025-599509 (Clockwise)

Preceding gene: 82750288

Following gene: 82750293

Centisome position: 21.81

GC content: 35.76

Gene sequence:

>1485_bases
ATGGAAAAAAAGAATAAGCAAATAGATAGAGGCGATTTAAAACAAAACCTATCTGAAAAGTTTGTATGGGCGATTGCATA
TGGTTCGTGTATCGGATGGGGCGCATTCATCTTACCAGGAGACTGGATTAAGCAGTCAGGTCCGATTGCAGCATCAATTG
GTATTGTTATTGGTGCATTATTAATGATATTAATTGCGGTTAGTTATGGCGCATTAGTAGAGAGATTTCCAGTATCAGGG
GGCGCGTTTGCCTTTAGTTTCTTAAGTTTCGGCAGATATGTGAGTTTCTTCTCATCATGGTTTTTAACTTTTGGTTATGT
CTGTGTCGTTGCTTTAAATGCGACCGCATTCAGTTTACTAGTTAAATTCTTATTGCCGGATGTCTTAAATAATGGGAAAC
TATACACCATTGCGGGCTGGGACGTTTATATTACGGAAATCATTATTGCGACCGTATTACTACTTGTATTCATGCTAGTA
ACGATTCGTGGCGCAAGTGTATCTGGATCATTACAATATCATTTCTGTGTGGCGATGGTAATCGTCGTATTATTGATGTT
CTTTGGTTCATTCTTTGGTAATAATTTTGCACTTGAAAATTTACAACCGTTAGCTGAACCTAGCAAAGGATGGTTAGTGT
CTATTGTGGTTATTGTATCCGTGGCACCATGGGCATATGTTGGATTTGATAATATTCCACAAACAGCAGAAGAGTTTAAC
TTTGCACCAAACAAGACATTTAAGCTTATCGTGTACAGTTTATTAGCAGCATCATTAACTTATGTTGTCATGATTTTATA
CACTGGTTGGTTATCAACAAGTCATCAAAGTTTAAATGGACAGTTGTGGTTAACAGGTGCTGTTACACAAACAGCATTTG
GTTATATTGGATTAGGTGTATTAGCAATTGCAATTATGATGGGTATATTTACTGGTTTAAATGGATTCTTGATGAGTTCA
AGTCGCTTGTTATTTTCTATGGGACGTTCAGGTATTATGCCAACAATGTTTAGTAAATTACATAGTAAATACAAAACACC
ATATGTCGCAATCATATTCCTAGTAAGTGTGTCTTTAATTGCACCATGGCTAGGAAGAACGGCATTGACTTGGATTGTAG
ATATGTCATCTACAGGTGTATCCATTGCCTACTTTATTACATGTTTGTCTGCTGCGAAATTATTCAGCTATAACAAACAA
AGTAATACGTATGCACCGGTTTACAAAACGTTTGCTATTATCGGCTCATTTGTATCATTCATTTTCTTAGCGTTGTTATT
AGTGCCAGGTTCTCCTGCAGCACTGACTGCACCATCTTATATTGCATTACTTGGATGGTTAATCATCGGTTTAATATTCT
TTGTCATTCGATATCCTAAATTGAAAAATATGGATAATGATGAATTAAGTCGCCTGATTTTAAATAGAAGTGAAAATGAA
GTTGATGATATGATTGAAGAACCTGAAAAAGAAAAAACTAAATAA

Upstream 100 bases:

>100_bases
CTATGTAACTAAACATTAAATTTTTAATAAAAATAATCAAGAAAAAGAGTTACAAACTCATCTTTTGGGTATAGAATACC
TTCGAGGTGAGTTTTTATTT

Downstream 100 bases:

>100_bases
TAAAAGAATCGCACAGTATACCTTCTTAATTCGAAGGCGTATCGTGCGATTTTTTGTATCATAAATTGACATTTAAGACG
AGGCAGTTAAACCTTATATA

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MEKKNKQIDRGDLKQNLSEKFVWAIAYGSCIGWGAFILPGDWIKQSGPIAASIGIVIGALLMILIAVSYGALVERFPVSG
GAFAFSFLSFGRYVSFFSSWFLTFGYVCVVALNATAFSLLVKFLLPDVLNNGKLYTIAGWDVYITEIIIATVLLLVFMLV
TIRGASVSGSLQYHFCVAMVIVVLLMFFGSFFGNNFALENLQPLAEPSKGWLVSIVVIVSVAPWAYVGFDNIPQTAEEFN
FAPNKTFKLIVYSLLAASLTYVVMILYTGWLSTSHQSLNGQLWLTGAVTQTAFGYIGLGVLAIAIMMGIFTGLNGFLMSS
SRLLFSMGRSGIMPTMFSKLHSKYKTPYVAIIFLVSVSLIAPWLGRTALTWIVDMSSTGVSIAYFITCLSAAKLFSYNKQ
SNTYAPVYKTFAIIGSFVSFIFLALLLVPGSPAALTAPSYIALLGWLIIGLIFFVIRYPKLKNMDNDELSRLILNRSENE
VDDMIEEPEKEKTK

Sequences:

>Translated_494_residues
MEKKNKQIDRGDLKQNLSEKFVWAIAYGSCIGWGAFILPGDWIKQSGPIAASIGIVIGALLMILIAVSYGALVERFPVSG
GAFAFSFLSFGRYVSFFSSWFLTFGYVCVVALNATAFSLLVKFLLPDVLNNGKLYTIAGWDVYITEIIIATVLLLVFMLV
TIRGASVSGSLQYHFCVAMVIVVLLMFFGSFFGNNFALENLQPLAEPSKGWLVSIVVIVSVAPWAYVGFDNIPQTAEEFN
FAPNKTFKLIVYSLLAASLTYVVMILYTGWLSTSHQSLNGQLWLTGAVTQTAFGYIGLGVLAIAIMMGIFTGLNGFLMSS
SRLLFSMGRSGIMPTMFSKLHSKYKTPYVAIIFLVSVSLIAPWLGRTALTWIVDMSSTGVSIAYFITCLSAAKLFSYNKQ
SNTYAPVYKTFAIIGSFVSFIFLALLLVPGSPAALTAPSYIALLGWLIIGLIFFVIRYPKLKNMDNDELSRLILNRSENE
VDDMIEEPEKEKTK
>Mature_494_residues
MEKKNKQIDRGDLKQNLSEKFVWAIAYGSCIGWGAFILPGDWIKQSGPIAASIGIVIGALLMILIAVSYGALVERFPVSG
GAFAFSFLSFGRYVSFFSSWFLTFGYVCVVALNATAFSLLVKFLLPDVLNNGKLYTIAGWDVYITEIIIATVLLLVFMLV
TIRGASVSGSLQYHFCVAMVIVVLLMFFGSFFGNNFALENLQPLAEPSKGWLVSIVVIVSVAPWAYVGFDNIPQTAEEFN
FAPNKTFKLIVYSLLAASLTYVVMILYTGWLSTSHQSLNGQLWLTGAVTQTAFGYIGLGVLAIAIMMGIFTGLNGFLMSS
SRLLFSMGRSGIMPTMFSKLHSKYKTPYVAIIFLVSVSLIAPWLGRTALTWIVDMSSTGVSIAYFITCLSAAKLFSYNKQ
SNTYAPVYKTFAIIGSFVSFIFLALLLVPGSPAALTAPSYIALLGWLIIGLIFFVIRYPKLKNMDNDELSRLILNRSENE
VDDMIEEPEKEKTK

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI181337167, Length=397, Percent_Identity=23.9294710327456, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI258614003, Length=412, Percent_Identity=25, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI258614005, Length=412, Percent_Identity=25, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI87082250, Length=412, Percent_Identity=24.2718446601942, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221512776, Length=397, Percent_Identity=23.6775818639798, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666159, Length=397, Percent_Identity=23.6775818639798, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24668806, Length=413, Percent_Identity=25.4237288135593, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356285, Length=413, Percent_Identity=25.4237288135593, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24668802, Length=413, Percent_Identity=25.4237288135593, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 54342; Mature: 54342

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS01331 THYMIDYLATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCCCCCCC
>Mature Secondary Structure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HHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]