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The map label for this gene is mvaIM [H]

Identifier: 82703344

GI number: 82703344

Start: 2526538

End: 2527941

Strand: Reverse

Name: mvaIM [H]

Synonym: Nmul_A2226

Alternate gene names: 82703344

Gene position: 2527941-2526538 (Counterclockwise)

Preceding gene: 82703345

Following gene: 82703343

Centisome position: 79.39

GC content: 43.73

Gene sequence:

>1404_bases
GTGAATCTATCTGGATTAGAAGAAGTGTATTCTCAAAGGATGCCAGAAAAGATAGACACTTCGGAAATGCTAAATCTGCT
CAAAACGGCATATATTACTACCGGCGAGCCGGTTGAAGTTGATTTTCGCTCGCTTGTCGATTGGGTAAAGATTGGAGACC
AATACTCTCACCTACTTCATCCGTACCCAGCGAAACTTTTACCACACATAGCCAACTTTTTTTTACGTTGTAGTTCATTG
GTTGGAAAGGAGGCGATGGTTTTGGATCCATTTTGCGGATCGGGAACAGTCGCTCTTGAAGCGTTTCTTGCTGGCCATAC
ACCGCTAATAGCAGATGCAAATCCCTTGGCACTGTTGATCGCTAAAGTTAAGACAACTACATTTAATGAGACGGTCTTGG
TACAACTTGCTAAGAGCATATGTTGTAGGGCAAAGTCTTTTCGAACCGCCCCAACGATACATGTTATAAACGATCATCTC
TGGTATTCGCCGAGAATTAAAATTGCCCTCGAAAAGCTTGTGAGGGCAATTAGGGAATTGCCGAGAAATATCGAGCGGGA
ATTTTTTGAGCTTTGCTTATCAGTGACCGCACGCCGTCTCAGTTTTGCTGATCCACGCATTTCAGTGCCAGTGCGACTAC
GGATAAAACCTAGTCTTGGAAACGTAGCTTCTAAAATAATTTCCGAACGCTTGGAATGGCTTCAAGACGTTAACGTGATT
GCAGAGTTCCAAAAAACTGTAGACACAAATATCCAACGAATCCAGCAGACTAATCGAGCTGCTAACGGTTGCCGGGCACG
AACCAAAATCGTCGGTAGTGATGCTCGTGATCTCAGAGAGTCTGTCTCAGGCACAAAGCTTCAAGACAATTGCGTGGATT
TGGTGATTACGTCGCCGCCTTATGGAAGTGCGCAAAAATATGTTCGTGCCAGCAGTCTTTCATTGAACTGGTTGGGCTAT
GCATCTCCAGACACACTAAAACATCTCGAACGTATCTCTATTGGGAGAGAGCATGTGCCGGCATCTTGGCAAATATCGAA
TGGAAGTCTTTCAAGTTCTTTCGAGAATCTTTTAGATCGGGTTGGGCAAAAAAATAGAACAAGGGAACGAATAACCAGGA
CGTACTTGATAGAGTTGCGGCAAGCAATGGTGGAAGTCGCGCGCGTAACCAAAGACGGAGGAACAATCATTGTAGTAGTA
GGAAATAATCAGGTCTGTGGTGAAACCTTGAGGAATGATGAATACTTGAAGGAAGTGTTAACTGATCTTCGATTTGAGAT
AACCCTGCATTTGATTGATCACATAAAATCCCGTGGCTTGATGACAAAGAGAAACAAGACTGCTTCTATTATTTCACGGG
AAAGTGTTCTCGTTTTCACGAAGAGTTTGTATAGAGGGAGCTAA

Upstream 100 bases:

>100_bases
TCCATTAAGAAGTTTTAAGAAGAGAAGCTTATTGATGCCAGTCGTTAATGAGATCTTCTCTTGGTGGCTTTATTGTTGGA
TTTGATGGGCAGATAGATTT

Downstream 100 bases:

>100_bases
ACGTGCTTGACGAGATGTCACTGCTAGAGGACAAAATTCGAGTCCTTGTTCAGGAAGCCTGGGAAAGAGAAGTTCATTGG
GCTGATATTGAGATGTGGCT

Product: hypothetical protein

Products: NA

Alternate protein names: M.MvaI; N-4 cytosine-specific methyltransferase MvaI [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MNLSGLEEVYSQRMPEKIDTSEMLNLLKTAYITTGEPVEVDFRSLVDWVKIGDQYSHLLHPYPAKLLPHIANFFLRCSSL
VGKEAMVLDPFCGSGTVALEAFLAGHTPLIADANPLALLIAKVKTTTFNETVLVQLAKSICCRAKSFRTAPTIHVINDHL
WYSPRIKIALEKLVRAIRELPRNIEREFFELCLSVTARRLSFADPRISVPVRLRIKPSLGNVASKIISERLEWLQDVNVI
AEFQKTVDTNIQRIQQTNRAANGCRARTKIVGSDARDLRESVSGTKLQDNCVDLVITSPPYGSAQKYVRASSLSLNWLGY
ASPDTLKHLERISIGREHVPASWQISNGSLSSSFENLLDRVGQKNRTRERITRTYLIELRQAMVEVARVTKDGGTIIVVV
GNNQVCGETLRNDEYLKEVLTDLRFEITLHLIDHIKSRGLMTKRNKTASIISRESVLVFTKSLYRGS

Sequences:

>Translated_467_residues
MNLSGLEEVYSQRMPEKIDTSEMLNLLKTAYITTGEPVEVDFRSLVDWVKIGDQYSHLLHPYPAKLLPHIANFFLRCSSL
VGKEAMVLDPFCGSGTVALEAFLAGHTPLIADANPLALLIAKVKTTTFNETVLVQLAKSICCRAKSFRTAPTIHVINDHL
WYSPRIKIALEKLVRAIRELPRNIEREFFELCLSVTARRLSFADPRISVPVRLRIKPSLGNVASKIISERLEWLQDVNVI
AEFQKTVDTNIQRIQQTNRAANGCRARTKIVGSDARDLRESVSGTKLQDNCVDLVITSPPYGSAQKYVRASSLSLNWLGY
ASPDTLKHLERISIGREHVPASWQISNGSLSSSFENLLDRVGQKNRTRERITRTYLIELRQAMVEVARVTKDGGTIIVVV
GNNQVCGETLRNDEYLKEVLTDLRFEITLHLIDHIKSRGLMTKRNKTASIISRESVLVFTKSLYRGS
>Mature_467_residues
MNLSGLEEVYSQRMPEKIDTSEMLNLLKTAYITTGEPVEVDFRSLVDWVKIGDQYSHLLHPYPAKLLPHIANFFLRCSSL
VGKEAMVLDPFCGSGTVALEAFLAGHTPLIADANPLALLIAKVKTTTFNETVLVQLAKSICCRAKSFRTAPTIHVINDHL
WYSPRIKIALEKLVRAIRELPRNIEREFFELCLSVTARRLSFADPRISVPVRLRIKPSLGNVASKIISERLEWLQDVNVI
AEFQKTVDTNIQRIQQTNRAANGCRARTKIVGSDARDLRESVSGTKLQDNCVDLVITSPPYGSAQKYVRASSLSLNWLGY
ASPDTLKHLERISIGREHVPASWQISNGSLSSSFENLLDRVGQKNRTRERITRTYLIELRQAMVEVARVTKDGGTIIVVV
GNNQVCGETLRNDEYLKEVLTDLRFEITLHLIDHIKSRGLMTKRNKTASIISRESVLVFTKSLYRGS

Specific function: This methylase recognizes the double-stranded sequence CCWGG, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the MvaI endonuclease [H]

COG id: COG0863

COG function: function code L; DNA modification methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017985
- InterPro:   IPR000241 [H]

Pfam domain/function: PF01170 UPF0020 [H]

EC number: =2.1.1.113 [H]

Molecular weight: Translated: 52527; Mature: 52527

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00093 N4_MTASE ; PS01261 UPF0020

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSGLEEVYSQRMPEKIDTSEMLNLLKTAYITTGEPVEVDFRSLVDWVKIGDQYSHLLH
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHCC
PYPAKLLPHIANFFLRCSSLVGKEAMVLDPFCGSGTVALEAFLAGHTPLIADANPLALLI
CCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHCCCCEEECCCCHHHHH
AKVKTTTFNETVLVQLAKSICCRAKSFRTAPTIHVINDHLWYSPRIKIALEKLVRAIREL
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCHHHHHHHHHHHHHHHH
PRNIEREFFELCLSVTARRLSFADPRISVPVRLRIKPSLGNVASKIISERLEWLQDVNVI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
AEFQKTVDTNIQRIQQTNRAANGCRARTKIVGSDARDLRESVSGTKLQDNCVDLVITSPP
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEEECCC
YGSAQKYVRASSLSLNWLGYASPDTLKHLERISIGREHVPASWQISNGSLSSSFENLLDR
CCCHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHH
VGQKNRTRERITRTYLIELRQAMVEVARVTKDGGTIIVVVGNNQVCGETLRNDEYLKEVL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCHHHHHHHH
TDLRFEITLHLIDHIKSRGLMTKRNKTASIISRESVLVFTKSLYRGS
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNLSGLEEVYSQRMPEKIDTSEMLNLLKTAYITTGEPVEVDFRSLVDWVKIGDQYSHLLH
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHCC
PYPAKLLPHIANFFLRCSSLVGKEAMVLDPFCGSGTVALEAFLAGHTPLIADANPLALLI
CCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHCCCCEEECCCCHHHHH
AKVKTTTFNETVLVQLAKSICCRAKSFRTAPTIHVINDHLWYSPRIKIALEKLVRAIREL
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCHHHHHHHHHHHHHHHH
PRNIEREFFELCLSVTARRLSFADPRISVPVRLRIKPSLGNVASKIISERLEWLQDVNVI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
AEFQKTVDTNIQRIQQTNRAANGCRARTKIVGSDARDLRESVSGTKLQDNCVDLVITSPP
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEEECCC
YGSAQKYVRASSLSLNWLGYASPDTLKHLERISIGREHVPASWQISNGSLSSSFENLLDR
CCCHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHH
VGQKNRTRERITRTYLIELRQAMVEVARVTKDGGTIIVVVGNNQVCGETLRNDEYLKEVL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCHHHHHHHH
TDLRFEITLHLIDHIKSRGLMTKRNKTASIISRESVLVFTKSLYRGS
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2690010 [H]