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The map label for this gene is abcA [H]

Identifier: 82703318

GI number: 82703318

Start: 2498321

End: 2499817

Strand: Direct

Name: abcA [H]

Synonym: Nmul_A2200

Alternate gene names: 82703318

Gene position: 2498321-2499817 (Clockwise)

Preceding gene: 82703313

Following gene: 82703319

Centisome position: 78.46

GC content: 54.84

Gene sequence:

>1497_bases
ATGACAGCCCCGAGAGAACTCACAGCCGAAACAAGATGCGGCTCCTCCATGGACTCCTCTCCCCCAACGGCAACCGATGA
TATCAATAGCGCAGATATTGCGCTTCGCGTATCGGCCCTGTCAAAGACCTATCGCATTTATGGCCGTTCGCAGGACCGGC
TGCTGCAAGGCTTGTGGGGTAACCGGAAGCAACTGTATCGGGAATTCCGGGCGCTGGACAGCATTTCCTTCGAGATTCGT
CGCGGGGAAACTTTCGGCATCATCGGTCCGAACGGATCCGGGAAAAGCACGCTGCTGCAACTGATCGCGGGAACGCTGAC
ACCCACTCAGGGTGAAATATATATCAAAGGCAAAGTCTCGGCTTTACTTGAGCTGGGAGCCGGCTTCAACGGGGAATTTA
CTGGCCGCGAGAATATCCGTATGGCGGCATCGATTGCGGGATTGAATCCTGGCGAGATCGGACAACGCCACGAGTGCATC
GCCGCTTATGCCGACATTGGCGATTTCCTCGATCAACCGGTAAAGACGTACTCAAGCGGCATGTATGTACGCCTTGCATT
CGCCGTCGCCATCTCGGTCGAGCCGGAGGTACTGATCATAGATGAAGCACTGGCGGTGGGGGACATGGAATTTCAGGCGA
AGTGCATGGTGACATTGAAGCAGATGCAGGAACGCGGCACCACCATTCTGTTTGTCAGCCATGATGTGGGAGCGGTGAGC
GCCTTATGTAAGCGGACCCTTTATCTCAAGCATGGCCGGGCACTGGAAATCGGTCCTACTCCTGACGTCGTTGCACGCTA
TATTCGTGAAGTACAGGAAGCAAACAACCGGAAAATAAATGTAACCGTTTCTGAAAACAACGATTCGAGAACCACGAGCC
CATCCGACGCTTCTGAGACCGGGATCGCTCCCTCCCACCGTACTGCTTCCCTCACCAGCGCTGAGGCCGCATCTGGAGCC
GCTTCTGGATTCTTGACGGCAGCAAGCCCGTTCCGGAGCGTGGAGAAGAAACATCTTGCACGCTTTGCTGAAAATGCAAA
TCACTGCCGCTCGGGAACCGGCGATGTGCGTGTAATTTACGCGGAAATGACAGATGATGAAGGACTGCCGGTACGCTCGG
CAGAATTCGGACAATCAGTCCTCATACGGATCATCGTTGAAGCCGCCCGCACCTGTACTTTTTCAGTCAACTACAAAATT
TGCGATAAGAATCGGACGCCGGTGATAGGAGCGGACTTCCTCATGCAAAGGCAGGCGCTGCTGACCCTGGAGCCGTCGCA
GCAGGCCGAGGCGCTTTACCGGACATCGCTCCCGCTGACCGACGGCAGATACAGCTTGAGAATTTCACTCACACACCCCG
TCAACGCCCATCAACAGGCACTGTTCTTCGATATCGTGGAGATCGCCCATGTATTCGAGGTGCTGCCCAATCCGACTGCA
AAGTTCTGGACACAGGTTTATCTGCCGAATACGCTCGATGTAAGGGTTCTGGAATGA

Upstream 100 bases:

>100_bases
ACTAAGATAATTCTCGGCATACATTCCATACATGCCATACTTCCCCATTCCATCCAAAGCGTTTGATCGTGCCAGAACGA
AACCTCGACGGGACTTTGTA

Downstream 100 bases:

>100_bases
GCGAGGCCCGGCGGAACAATCTTTCCGACAATCTTCCCGGCAATCTTTACGGGACGGGCAATTTGCTGGTCATCGCCCAT
CCGGGGCATGAATTGCGCCT

Product: ABC transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MTAPRELTAETRCGSSMDSSPPTATDDINSADIALRVSALSKTYRIYGRSQDRLLQGLWGNRKQLYREFRALDSISFEIR
RGETFGIIGPNGSGKSTLLQLIAGTLTPTQGEIYIKGKVSALLELGAGFNGEFTGRENIRMAASIAGLNPGEIGQRHECI
AAYADIGDFLDQPVKTYSSGMYVRLAFAVAISVEPEVLIIDEALAVGDMEFQAKCMVTLKQMQERGTTILFVSHDVGAVS
ALCKRTLYLKHGRALEIGPTPDVVARYIREVQEANNRKINVTVSENNDSRTTSPSDASETGIAPSHRTASLTSAEAASGA
ASGFLTAASPFRSVEKKHLARFAENANHCRSGTGDVRVIYAEMTDDEGLPVRSAEFGQSVLIRIIVEAARTCTFSVNYKI
CDKNRTPVIGADFLMQRQALLTLEPSQQAEALYRTSLPLTDGRYSLRISLTHPVNAHQQALFFDIVEIAHVFEVLPNPTA
KFWTQVYLPNTLDVRVLE

Sequences:

>Translated_498_residues
MTAPRELTAETRCGSSMDSSPPTATDDINSADIALRVSALSKTYRIYGRSQDRLLQGLWGNRKQLYREFRALDSISFEIR
RGETFGIIGPNGSGKSTLLQLIAGTLTPTQGEIYIKGKVSALLELGAGFNGEFTGRENIRMAASIAGLNPGEIGQRHECI
AAYADIGDFLDQPVKTYSSGMYVRLAFAVAISVEPEVLIIDEALAVGDMEFQAKCMVTLKQMQERGTTILFVSHDVGAVS
ALCKRTLYLKHGRALEIGPTPDVVARYIREVQEANNRKINVTVSENNDSRTTSPSDASETGIAPSHRTASLTSAEAASGA
ASGFLTAASPFRSVEKKHLARFAENANHCRSGTGDVRVIYAEMTDDEGLPVRSAEFGQSVLIRIIVEAARTCTFSVNYKI
CDKNRTPVIGADFLMQRQALLTLEPSQQAEALYRTSLPLTDGRYSLRISLTHPVNAHQQALFFDIVEIAHVFEVLPNPTA
KFWTQVYLPNTLDVRVLE
>Mature_497_residues
TAPRELTAETRCGSSMDSSPPTATDDINSADIALRVSALSKTYRIYGRSQDRLLQGLWGNRKQLYREFRALDSISFEIRR
GETFGIIGPNGSGKSTLLQLIAGTLTPTQGEIYIKGKVSALLELGAGFNGEFTGRENIRMAASIAGLNPGEIGQRHECIA
AYADIGDFLDQPVKTYSSGMYVRLAFAVAISVEPEVLIIDEALAVGDMEFQAKCMVTLKQMQERGTTILFVSHDVGAVSA
LCKRTLYLKHGRALEIGPTPDVVARYIREVQEANNRKINVTVSENNDSRTTSPSDASETGIAPSHRTASLTSAEAASGAA
SGFLTAASPFRSVEKKHLARFAENANHCRSGTGDVRVIYAEMTDDEGLPVRSAEFGQSVLIRIIVEAARTCTFSVNYKIC
DKNRTPVIGADFLMQRQALLTLEPSQQAEALYRTSLPLTDGRYSLRISLTHPVNAHQQALFFDIVEIAHVFEVLPNPTAK
FWTQVYLPNTLDVRVLE

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI6005701, Length=228, Percent_Identity=28.0701754385965, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI150417984, Length=239, Percent_Identity=25.9414225941423, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI27477115, Length=224, Percent_Identity=27.2321428571429, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI27436953, Length=225, Percent_Identity=26.6666666666667, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI153792144, Length=196, Percent_Identity=30.6122448979592, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI30795238, Length=229, Percent_Identity=22.707423580786, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI27881501, Length=229, Percent_Identity=22.707423580786, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI116734710, Length=208, Percent_Identity=26.4423076923077, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI47078218, Length=210, Percent_Identity=24.7619047619048, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI45446740, Length=210, Percent_Identity=24.7619047619048, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI21536376, Length=220, Percent_Identity=26.3636363636364, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI31657092, Length=238, Percent_Identity=24.3697478991597, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI27262624, Length=210, Percent_Identity=21.9047619047619, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI27262626, Length=210, Percent_Identity=21.9047619047619, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI105990541, Length=195, Percent_Identity=27.1794871794872, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789891, Length=210, Percent_Identity=30.952380952381, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787712, Length=224, Percent_Identity=30.8035714285714, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI48994997, Length=232, Percent_Identity=28.448275862069, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790467, Length=209, Percent_Identity=28.2296650717703, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87081709, Length=205, Percent_Identity=27.8048780487805, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87081782, Length=231, Percent_Identity=25.5411255411255, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1786319, Length=198, Percent_Identity=28.7878787878788, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789032, Length=251, Percent_Identity=26.6932270916335, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082267, Length=205, Percent_Identity=26.8292682926829, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI48995001, Length=206, Percent_Identity=29.126213592233, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87081791, Length=210, Percent_Identity=25.7142857142857, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI48994943, Length=257, Percent_Identity=27.6264591439689, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786253, Length=209, Percent_Identity=31.5789473684211, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787029, Length=212, Percent_Identity=27.8301886792453, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788761, Length=222, Percent_Identity=27.4774774774775, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786398, Length=206, Percent_Identity=25.7281553398058, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789751, Length=212, Percent_Identity=29.2452830188679, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788165, Length=205, Percent_Identity=27.3170731707317, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787089, Length=213, Percent_Identity=26.7605633802817, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788225, Length=223, Percent_Identity=29.1479820627803, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786703, Length=214, Percent_Identity=28.9719626168224, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790525, Length=216, Percent_Identity=25.9259259259259, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081834, Length=199, Percent_Identity=28.643216080402, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1787370, Length=237, Percent_Identity=26.1603375527426, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787164, Length=195, Percent_Identity=29.2307692307692, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788210, Length=207, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789873, Length=202, Percent_Identity=27.7227722772277, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1786653, Length=214, Percent_Identity=27.1028037383178, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1786563, Length=205, Percent_Identity=30.7317073170732, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=218, Percent_Identity=26.1467889908257, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115533608, Length=214, Percent_Identity=24.7663551401869, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71983523, Length=269, Percent_Identity=24.907063197026, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71983516, Length=269, Percent_Identity=24.907063197026, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71983510, Length=269, Percent_Identity=24.907063197026, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17510237, Length=209, Percent_Identity=24.8803827751196, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24648314, Length=225, Percent_Identity=27.5555555555556, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24666092, Length=228, Percent_Identity=25.8771929824561, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24643674, Length=215, Percent_Identity=24.1860465116279, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI221512771, Length=190, Percent_Identity=27.3684210526316, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28573571, Length=263, Percent_Identity=25.4752851711027, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28573573, Length=263, Percent_Identity=25.4752851711027, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI116007184, Length=191, Percent_Identity=26.7015706806283, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221500365, Length=191, Percent_Identity=26.7015706806283, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI85725262, Length=239, Percent_Identity=25.1046025104602, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 54433; Mature: 54302

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPRELTAETRCGSSMDSSPPTATDDINSADIALRVSALSKTYRIYGRSQDRLLQGLWG
CCCCHHCCHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHEECCCHHHHHHHHCC
NRKQLYREFRALDSISFEIRRGETFGIIGPNGSGKSTLLQLIAGTLTPTQGEIYIKGKVS
CHHHHHHHHHHHHCCEEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEHHH
ALLELGAGFNGEFTGRENIRMAASIAGLNPGEIGQRHECIAAYADIGDFLDQPVKTYSSG
HHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
MYVRLAFAVAISVEPEVLIIDEALAVGDMEFQAKCMVTLKQMQERGTTILFVSHDVGAVS
EEEEEEEEEEEECCCCEEEEECHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHH
ALCKRTLYLKHGRALEIGPTPDVVARYIREVQEANNRKINVTVSENNDSRTTSPSDASET
HHHHHHHHEECCCEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCC
GIAPSHRTASLTSAEAASGAASGFLTAASPFRSVEKKHLARFAENANHCRSGTGDVRVIY
CCCCCCCCCCCCCHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEE
AEMTDDEGLPVRSAEFGQSVLIRIIVEAARTCTFSVNYKICDKNRTPVIGADFLMQRQAL
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCEECHHHHHHCCCE
LTLEPSQQAEALYRTSLPLTDGRYSLRISLTHPVNAHQQALFFDIVEIAHVFEVLPNPTA
EEECCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCH
KFWTQVYLPNTLDVRVLE
HHEEEEECCCCCEEEEEC
>Mature Secondary Structure 
TAPRELTAETRCGSSMDSSPPTATDDINSADIALRVSALSKTYRIYGRSQDRLLQGLWG
CCCHHCCHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHEECCCHHHHHHHHCC
NRKQLYREFRALDSISFEIRRGETFGIIGPNGSGKSTLLQLIAGTLTPTQGEIYIKGKVS
CHHHHHHHHHHHHCCEEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEHHH
ALLELGAGFNGEFTGRENIRMAASIAGLNPGEIGQRHECIAAYADIGDFLDQPVKTYSSG
HHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
MYVRLAFAVAISVEPEVLIIDEALAVGDMEFQAKCMVTLKQMQERGTTILFVSHDVGAVS
EEEEEEEEEEEECCCCEEEEECHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHH
ALCKRTLYLKHGRALEIGPTPDVVARYIREVQEANNRKINVTVSENNDSRTTSPSDASET
HHHHHHHHEECCCEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCC
GIAPSHRTASLTSAEAASGAASGFLTAASPFRSVEKKHLARFAENANHCRSGTGDVRVIY
CCCCCCCCCCCCCHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEE
AEMTDDEGLPVRSAEFGQSVLIRIIVEAARTCTFSVNYKICDKNRTPVIGADFLMQRQAL
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCEECHHHHHHCCCE
LTLEPSQQAEALYRTSLPLTDGRYSLRISLTHPVNAHQQALFFDIVEIAHVFEVLPNPTA
EEECCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCH
KFWTQVYLPNTLDVRVLE
HHEEEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]