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The map label for this gene is aroF [H]

Identifier: 82703312

GI number: 82703312

Start: 2492832

End: 2493848

Strand: Direct

Name: aroF [H]

Synonym: Nmul_A2194

Alternate gene names: 82703312

Gene position: 2492832-2493848 (Clockwise)

Preceding gene: 82703311

Following gene: 82703313

Centisome position: 78.29

GC content: 56.34

Gene sequence:

>1017_bases
GTGATCATAGTCATGAATAACGGCGCCACCGAAGAGCAGATCGAAACGGTGGTTGCAAAAATTCGAAGCTTCGACCTGGA
CGCGAACGTTTCGCGTGGCACCGAGCGTACCGTAATCGGCGCAATTGGCAATGAGCGCAAGCTCAGTCCCGAAATGTTCG
ATACCCTGAGCGGTGTCGAATATTCCATGCATATCGTCAAGCAGTACAAGATCGTGTCGCGCGAATGGCACAGGGATAAT
TCGATAATCAATGTGGGAGATGTGGCGATTGGCGGGGACCAGGTGCAGGTGATCGGAGGTCCCTGTTCAGTGGAGACGCA
AGAGCAAATGGATTCGGCGGCCCAACATGTCTCGGATGCCGGATGCCGGCTGATGCGGGGCGGCGCCTTCAAGCCCCGTA
CCAGTCCCTATACCTTCCAGGGCAATGGCGAAGAAGGATTGAAAATGTTCCGCAAGGCTGCGGATAAGCACAACCTCCGG
ATCGTCACGGAATTGATGGATGCGCGCATGCTGGACACTTTCCTCGAGTATGACGTGGATGTGATCCAGATCGGTACACG
CAGCATGCAGAACTTCGAACTTTTGAAAGAAGTGGGGCGCATCAACAAGCCCGTGATACTGAAGCGCGGGATGTCCGCGA
CCGTTTCCGAGTGGCTCATGGCCGCGGAATACATCGCCGCGGGCGGCAACCATAACATCATTTTCTGCGAACGCGGCATA
CGCACCTTTGAAACCGCTTATCGCAACGTAATGGATGTAACCTGCATCCCCGTGCTAAAAAAAGAAACGCACTTGCCGGT
AATCGTCGATCCCTCCCATGCGGGGGGAAAGGCATGGATGGTGCCCGCCCTGGCGCGCGCGGCAGTTGCAGCGGGAGCGG
ATGGCCTGCTGGTAGAGACGCATCCCAATCCATGCGAAGCCTGGTGCGACGCAGACCAGGCGTTGAATCCCGAGGAATTC
CGCGATCTGATGGGATCGCTGCAAGGAATAGCGGCAGTAATCGGACGGAGTCTGTGA

Upstream 100 bases:

>100_bases
AATCGCTGGCGATAGCCCTGGAGACGACGGAAGGGGCAGCAGCAGACACAATACCTGAGATGGCGGTAAGCTTTCCCAAA
GTTGCATCGGGGGGAACAGC

Downstream 100 bases:

>100_bases
TGAATAGCCGCTCCACCTGATAGCCATGCGAGGCTTGATATCAACCGCTCATATAAACCCCTCATATAAACCGATGCCGA
CAATGACTACTACTGTGATC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MIIVMNNGATEEQIETVVAKIRSFDLDANVSRGTERTVIGAIGNERKLSPEMFDTLSGVEYSMHIVKQYKIVSREWHRDN
SIINVGDVAIGGDQVQVIGGPCSVETQEQMDSAAQHVSDAGCRLMRGGAFKPRTSPYTFQGNGEEGLKMFRKAADKHNLR
IVTELMDARMLDTFLEYDVDVIQIGTRSMQNFELLKEVGRINKPVILKRGMSATVSEWLMAAEYIAAGGNHNIIFCERGI
RTFETAYRNVMDVTCIPVLKKETHLPVIVDPSHAGGKAWMVPALARAAVAAGADGLLVETHPNPCEAWCDADQALNPEEF
RDLMGSLQGIAAVIGRSL

Sequences:

>Translated_338_residues
MIIVMNNGATEEQIETVVAKIRSFDLDANVSRGTERTVIGAIGNERKLSPEMFDTLSGVEYSMHIVKQYKIVSREWHRDN
SIINVGDVAIGGDQVQVIGGPCSVETQEQMDSAAQHVSDAGCRLMRGGAFKPRTSPYTFQGNGEEGLKMFRKAADKHNLR
IVTELMDARMLDTFLEYDVDVIQIGTRSMQNFELLKEVGRINKPVILKRGMSATVSEWLMAAEYIAAGGNHNIIFCERGI
RTFETAYRNVMDVTCIPVLKKETHLPVIVDPSHAGGKAWMVPALARAAVAAGADGLLVETHPNPCEAWCDADQALNPEEF
RDLMGSLQGIAAVIGRSL
>Mature_338_residues
MIIVMNNGATEEQIETVVAKIRSFDLDANVSRGTERTVIGAIGNERKLSPEMFDTLSGVEYSMHIVKQYKIVSREWHRDN
SIINVGDVAIGGDQVQVIGGPCSVETQEQMDSAAQHVSDAGCRLMRGGAFKPRTSPYTFQGNGEEGLKMFRKAADKHNLR
IVTELMDARMLDTFLEYDVDVIQIGTRSMQNFELLKEVGRINKPVILKRGMSATVSEWLMAAEYIAAGGNHNIIFCERGI
RTFETAYRNVMDVTCIPVLKKETHLPVIVDPSHAGGKAWMVPALARAAVAAGADGLLVETHPNPCEAWCDADQALNPEEF
RDLMGSLQGIAAVIGRSL

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=272, Percent_Identity=25.3676470588235, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 37123; Mature: 37123

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVMNNGATEEQIETVVAKIRSFDLDANVSRGTERTVIGAIGNERKLSPEMFDTLSGVE
CEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCCH
YSMHIVKQYKIVSREWHRDNSIINVGDVAIGGDQVQVIGGPCSVETQEQMDSAAQHVSDA
HHHHHHHHHHHHHHHHCCCCCEEEECCEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHH
GCRLMRGGAFKPRTSPYTFQGNGEEGLKMFRKAADKHNLRIVTELMDARMLDTFLEYDVD
CCHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCE
VIQIGTRSMQNFELLKEVGRINKPVILKRGMSATVSEWLMAAEYIAAGGNHNIIFCERGI
EEEECCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCC
RTFETAYRNVMDVTCIPVLKKETHLPVIVDPSHAGGKAWMVPALARAAVAAGADGLLVET
HHHHHHHHHHHHHHEEHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEC
HPNPCEAWCDADQALNPEEFRDLMGSLQGIAAVIGRSL
CCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIIVMNNGATEEQIETVVAKIRSFDLDANVSRGTERTVIGAIGNERKLSPEMFDTLSGVE
CEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCCH
YSMHIVKQYKIVSREWHRDNSIINVGDVAIGGDQVQVIGGPCSVETQEQMDSAAQHVSDA
HHHHHHHHHHHHHHHHCCCCCEEEECCEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHH
GCRLMRGGAFKPRTSPYTFQGNGEEGLKMFRKAADKHNLRIVTELMDARMLDTFLEYDVD
CCHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCE
VIQIGTRSMQNFELLKEVGRINKPVILKRGMSATVSEWLMAAEYIAAGGNHNIIFCERGI
EEEECCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCC
RTFETAYRNVMDVTCIPVLKKETHLPVIVDPSHAGGKAWMVPALARAAVAAGADGLLVET
HHHHHHHHHHHHHHEEHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEC
HPNPCEAWCDADQALNPEEFRDLMGSLQGIAAVIGRSL
CCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]