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The map label for this gene is gcp

Identifier: 82703181

GI number: 82703181

Start: 2353857

End: 2354900

Strand: Direct

Name: gcp

Synonym: Nmul_A2061

Alternate gene names: 82703181

Gene position: 2353857-2354900 (Clockwise)

Preceding gene: 82703172

Following gene: 82703183

Centisome position: 73.92

GC content: 56.61

Gene sequence:

>1044_bases
TTGCTCGTACTCGGAATTGAAACCTCCTGCGATGAAACGGGTGTCGCACTTTATCACACCCAGCAGGGCTTACTCAGCCA
TGCGCTATATTCGCAAATCGAAATGCATGGGGAATATGGCGGAGTAGTTCCCGAACTCGCCTCCCGCGACCACATCAGGC
GGTTGCTGCCCCTCATCCGGCAGATATTTGCGGAAGCCGGCGTCTCACTGCGAGATCTGGATGCCATTGCATACACCCAG
GGTCCCGGACTTGCCGGGGCCTTGCTCGTGGGTGCAAGCGTGGCAGCCGCGCTTGGTTTTGCGCTCAAAGTTCCCGTGCT
GGGGATTCACCACCTCGAAGGCCATCTTTTATCTCCTCTGCTCTCCGACCCCGCTCCTGCTTTTCCATTCGTAGCCCTGC
TTGTATCGGGGGGTCATACGCAACTGATGGAAGTGACCGGTCTGGGGCAGTACCGATTGCTTGGCGAAACTGTGGACGAT
GCGGCAGGAGAAGCCTTCGACAAGACGGCCAAGCTGCTCGGTCTGGGTTATCCAGGAGGGCCCGCGCTTTCCCGTCTGGC
GGATGAATTTACCCGATCAGGCCAATCCGCGCGCTTCGAGCTTCCACGACCCATGCTCCATAGCGGCGATTTCAATTTCA
GCTTCAGTGGCCTCAAAACCGCCGTCCTGACGCTGGTGAACAAACACGAGATGACACCCCAGATTCGCGGTGCGATCGCA
CAAGCTTTCCAGGAGGCGGCAGTCGAAGTGCTGACCGAGAAATCGCTTGCGGCACTTGCAAAAACGGGACTTACCCAACT
GGTAGTGGCTGGCGGGGTAGGAGCCAATCGTCAATTGAGGAGTAATCTCGACCGCAGGGCAGGAACGATTGGCGCGACAG
TATATTATCCGAAACTCGAATTCTGCACTGACAACGGGGCAATGATCGCATTTGCGGGAGCAATGCGTCTGGAATCTGGA
GAGTCTGAAAGTTCAAGGCTTGGCAAGTTCACGATAAACGCCCGCTGGGATCTGGAAATGCAGGAAATCGGGCGAGAAGC
ATAA

Upstream 100 bases:

>100_bases
TGACGATCGGTCTTCGTCTAAATATAGACAGCCCACTATTATATAACAAGTAACAATTCCTAAAAAACTCCTGTAAAGAA
TCTGATTCTCCCTGCCTCAA

Downstream 100 bases:

>100_bases
GATGCCATCTGTTTCCGCACTTGTTCTGCTCCCCCGACAATATACCGGGAAGGCGGAGTGCCCAGCCCTCAAGAGGTACT
GCGCTTGCCAATGCGCGATT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MLVLGIETSCDETGVALYHTQQGLLSHALYSQIEMHGEYGGVVPELASRDHIRRLLPLIRQIFAEAGVSLRDLDAIAYTQ
GPGLAGALLVGASVAAALGFALKVPVLGIHHLEGHLLSPLLSDPAPAFPFVALLVSGGHTQLMEVTGLGQYRLLGETVDD
AAGEAFDKTAKLLGLGYPGGPALSRLADEFTRSGQSARFELPRPMLHSGDFNFSFSGLKTAVLTLVNKHEMTPQIRGAIA
QAFQEAAVEVLTEKSLAALAKTGLTQLVVAGGVGANRQLRSNLDRRAGTIGATVYYPKLEFCTDNGAMIAFAGAMRLESG
ESESSRLGKFTINARWDLEMQEIGREA

Sequences:

>Translated_347_residues
MLVLGIETSCDETGVALYHTQQGLLSHALYSQIEMHGEYGGVVPELASRDHIRRLLPLIRQIFAEAGVSLRDLDAIAYTQ
GPGLAGALLVGASVAAALGFALKVPVLGIHHLEGHLLSPLLSDPAPAFPFVALLVSGGHTQLMEVTGLGQYRLLGETVDD
AAGEAFDKTAKLLGLGYPGGPALSRLADEFTRSGQSARFELPRPMLHSGDFNFSFSGLKTAVLTLVNKHEMTPQIRGAIA
QAFQEAAVEVLTEKSLAALAKTGLTQLVVAGGVGANRQLRSNLDRRAGTIGATVYYPKLEFCTDNGAMIAFAGAMRLESG
ESESSRLGKFTINARWDLEMQEIGREA
>Mature_347_residues
MLVLGIETSCDETGVALYHTQQGLLSHALYSQIEMHGEYGGVVPELASRDHIRRLLPLIRQIFAEAGVSLRDLDAIAYTQ
GPGLAGALLVGASVAAALGFALKVPVLGIHHLEGHLLSPLLSDPAPAFPFVALLVSGGHTQLMEVTGLGQYRLLGETVDD
AAGEAFDKTAKLLGLGYPGGPALSRLADEFTRSGQSARFELPRPMLHSGDFNFSFSGLKTAVLTLVNKHEMTPQIRGAIA
QAFQEAAVEVLTEKSLAALAKTGLTQLVVAGGVGANRQLRSNLDRRAGTIGATVYYPKLEFCTDNGAMIAFAGAMRLESG
ESESSRLGKFTINARWDLEMQEIGREA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=342, Percent_Identity=35.3801169590643, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI8923380, Length=322, Percent_Identity=29.8136645962733, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1789445, Length=338, Percent_Identity=55.9171597633136, Blast_Score=383, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17557464, Length=330, Percent_Identity=33.030303030303, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71995670, Length=344, Percent_Identity=30.8139534883721, Blast_Score=127, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320099, Length=346, Percent_Identity=30.9248554913295, Blast_Score=160, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6322891, Length=357, Percent_Identity=26.890756302521, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI20129063, Length=357, Percent_Identity=33.0532212885154, Blast_Score=178, Evalue=6e-45,
Organism=Drosophila melanogaster, GI21357207, Length=332, Percent_Identity=31.0240963855422, Blast_Score=135, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_NITMU (Q2Y7B6)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_412747.1
- ProteinModelPortal:   Q2Y7B6
- SMR:   Q2Y7B6
- STRING:   Q2Y7B6
- MEROPS:   M22.001
- GeneID:   3784379
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A2061
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- PhylomeDB:   Q2Y7B6
- ProtClustDB:   PRK09604
- BioCyc:   NMUL323848:NMUL_A2061-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36865; Mature: 36865

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVLGIETSCDETGVALYHTQQGLLSHALYSQIEMHGEYGGVVPELASRDHIRRLLPLIR
CEEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHH
QIFAEAGVSLRDLDAIAYTQGPGLAGALLVGASVAAALGFALKVPVLGIHHLEGHLLSPL
HHHHHCCCCHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHH
LSDPAPAFPFVALLVSGGHTQLMEVTGLGQYRLLGETVDDAAGEAFDKTAKLLGLGYPGG
HCCCCCHHHHHHHHHCCCCCEEEEECCCCCEEECCCHHHHHCCHHHHHHHHHHCCCCCCC
PALSRLADEFTRSGQSARFELPRPMLHSGDFNFSFSGLKTAVLTLVNKHEMTPQIRGAIA
HHHHHHHHHHHHCCCCCEECCCCCHHHCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHH
QAFQEAAVEVLTEKSLAALAKTGLTQLVVAGGVGANRQLRSNLDRRAGTIGATVYYPKLE
HHHHHHHHHHHHHHHHHHHHHHCHHHHHEECCCCCCHHHHHHHHHHCCCCCEEEEECCEE
FCTDNGAMIAFAGAMRLESGESESSRLGKFTINARWDLEMQEIGREA
EECCCCCEEEEECHHHCCCCCCCHHCCCEEEEEEEECCCHHHCCCCC
>Mature Secondary Structure
MLVLGIETSCDETGVALYHTQQGLLSHALYSQIEMHGEYGGVVPELASRDHIRRLLPLIR
CEEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHH
QIFAEAGVSLRDLDAIAYTQGPGLAGALLVGASVAAALGFALKVPVLGIHHLEGHLLSPL
HHHHHCCCCHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHH
LSDPAPAFPFVALLVSGGHTQLMEVTGLGQYRLLGETVDDAAGEAFDKTAKLLGLGYPGG
HCCCCCHHHHHHHHHCCCCCEEEEECCCCCEEECCCHHHHHCCHHHHHHHHHHCCCCCCC
PALSRLADEFTRSGQSARFELPRPMLHSGDFNFSFSGLKTAVLTLVNKHEMTPQIRGAIA
HHHHHHHHHHHHCCCCCEECCCCCHHHCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHH
QAFQEAAVEVLTEKSLAALAKTGLTQLVVAGGVGANRQLRSNLDRRAGTIGATVYYPKLE
HHHHHHHHHHHHHHHHHHHHHHCHHHHHEECCCCCCHHHHHHHHHHCCCCCEEEEECCEE
FCTDNGAMIAFAGAMRLESGESESSRLGKFTINARWDLEMQEIGREA
EECCCCCEEEEECHHHCCCCCCCHHCCCEEEEEEEECCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA