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The map label for this gene is mdtA [H]

Identifier: 82703092

GI number: 82703092

Start: 2268771

End: 2269859

Strand: Reverse

Name: mdtA [H]

Synonym: Nmul_A1971

Alternate gene names: 82703092

Gene position: 2269859-2268771 (Counterclockwise)

Preceding gene: 82703093

Following gene: 82703091

Centisome position: 71.28

GC content: 57.21

Gene sequence:

>1089_bases
ATGTGGCGTAACCCGAGTGGCGCGATCGATGCGAAGAAGAAGACTTCGGAACCTACGCCGGTAATAACAGCGGTCATCAA
CCAGCAGAACGTACCGGTACAACTCGCTGCCAACGGTACCGTGTCGGCGCAGCAGATGGTGGCCGTGCGTCCCCAGCTGA
GCGCAATGATCAGCGCCGTGCATATCAGGGAAGGTCAATTCGTTCGAAAGGGCGAGCCGCTTTTCACGCTCGACGCGCGC
ACTGAGGATGCCAATGTGCGCAGAACAGAGGGGCAACTGGCGAAGTCACGTGCCGATTTGAGAAATGCGGAACGTAATCT
TGAACGCCAGCGGGAACTGTTCAGGCAGGATTTTATTTCGCAGGCGGCCCTGGATGTGGCGGAGAATCAGGTGGATGCGC
TACGCGCCCAGCTTACAGTCGATGAGGCTACAGCTCAGGCGAATAGAATCGCCCGCGGCTTCAGCGAAATCACTGCCCCG
ATCTCTGGTCGTTCGGGCGCCATTTCGGTATATCAGGGCAGCTTGGTGCAGCCCAATGATGCTTTGGTGAGCATTACCCA
GATCGATCCGATCAACGTCAGCTTCACCTTGCCGGAACGCGACTTCATACCTTTGCAGCAGGCTTTTGCGAAAGGCGAAG
TGCCGGTAACCGTCGAGCTGAATGGGCCGCAAAAACAGACAAGAACGGGCCGCCTGATATTTATCGATAATGCCGTCGAT
ACGGCAAGCGGTACAATTCGTCTCAAGGCAGAGTTTCCCAATGCCGACAGGCACCTGTGGCCAGGCATGTTTGTCATGGT
GTCGCTCGCGCCGCAAACTTTGATCCATGCTCTGACGGTGCCGGTGCAGGCCGTGCAGAATGGACCGGAAGGAAAATTCC
TGTATGTACTGGACGAAACCGGAAAGGTAAAGCCTTTTTCGGTCGAGGTGCGCCTGGTACAGGAAGGGGTTGCGGTAGTA
GAGGGAAAGGCCATTACTTCCGGGATGCATGTGGTAGCGGAGGGGGCGCAGAATCTCCGTCCGGGCAGCGCCGTAACGGA
GGCGAGTTCCATCAAGACTGGTGCCGGGGCAGCGGGTAGAAACTCCTGA

Upstream 100 bases:

>100_bases
GATGGAAGCTATTTCTGAAATAAAAAGGACTACACCTGTCCGACGCCTGAGAGTCACAATCCTTGGTTTTATACTGGCTG
CCCTGATAGCGGGGACCTGG

Downstream 100 bases:

>100_bases
TGAGCAAATTGTTTTGGCAGGGCCGATCTGCAACAGCATGAAGTCAGCGCGATGAATCTCTCGGAACTGTGCATTCGCCG
TCCCATCATGACGGTGCTGT

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MWRNPSGAIDAKKKTSEPTPVITAVINQQNVPVQLAANGTVSAQQMVAVRPQLSAMISAVHIREGQFVRKGEPLFTLDAR
TEDANVRRTEGQLAKSRADLRNAERNLERQRELFRQDFISQAALDVAENQVDALRAQLTVDEATAQANRIARGFSEITAP
ISGRSGAISVYQGSLVQPNDALVSITQIDPINVSFTLPERDFIPLQQAFAKGEVPVTVELNGPQKQTRTGRLIFIDNAVD
TASGTIRLKAEFPNADRHLWPGMFVMVSLAPQTLIHALTVPVQAVQNGPEGKFLYVLDETGKVKPFSVEVRLVQEGVAVV
EGKAITSGMHVVAEGAQNLRPGSAVTEASSIKTGAGAAGRNS

Sequences:

>Translated_362_residues
MWRNPSGAIDAKKKTSEPTPVITAVINQQNVPVQLAANGTVSAQQMVAVRPQLSAMISAVHIREGQFVRKGEPLFTLDAR
TEDANVRRTEGQLAKSRADLRNAERNLERQRELFRQDFISQAALDVAENQVDALRAQLTVDEATAQANRIARGFSEITAP
ISGRSGAISVYQGSLVQPNDALVSITQIDPINVSFTLPERDFIPLQQAFAKGEVPVTVELNGPQKQTRTGRLIFIDNAVD
TASGTIRLKAEFPNADRHLWPGMFVMVSLAPQTLIHALTVPVQAVQNGPEGKFLYVLDETGKVKPFSVEVRLVQEGVAVV
EGKAITSGMHVVAEGAQNLRPGSAVTEASSIKTGAGAAGRNS
>Mature_362_residues
MWRNPSGAIDAKKKTSEPTPVITAVINQQNVPVQLAANGTVSAQQMVAVRPQLSAMISAVHIREGQFVRKGEPLFTLDAR
TEDANVRRTEGQLAKSRADLRNAERNLERQRELFRQDFISQAALDVAENQVDALRAQLTVDEATAQANRIARGFSEITAP
ISGRSGAISVYQGSLVQPNDALVSITQIDPINVSFTLPERDFIPLQQAFAKGEVPVTVELNGPQKQTRTGRLIFIDNAVD
TASGTIRLKAEFPNADRHLWPGMFVMVSLAPQTLIHALTVPVQAVQNGPEGKFLYVLDETGKVKPFSVEVRLVQEGVAVV
EGKAITSGMHVVAEGAQNLRPGSAVTEASSIKTGAGAAGRNS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=340, Percent_Identity=34.7058823529412, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1789929, Length=311, Percent_Identity=29.903536977492, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1789665, Length=322, Percent_Identity=32.9192546583851, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786668, Length=339, Percent_Identity=31.858407079646, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI87081951, Length=126, Percent_Identity=34.1269841269841, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38986; Mature: 38986

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWRNPSGAIDAKKKTSEPTPVITAVINQQNVPVQLAANGTVSAQQMVAVRPQLSAMISAV
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCHHHHEEECHHHHHHHHHH
HIREGQFVRKGEPLFTLDARTEDANVRRTEGQLAKSRADLRNAERNLERQRELFRQDFIS
EECCCCEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAALDVAENQVDALRAQLTVDEATAQANRIARGFSEITAPISGRSGAISVYQGSLVQPND
HHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEECCCC
ALVSITQIDPINVSFTLPERDFIPLQQAFAKGEVPVTVELNGPQKQTRTGRLIFIDNAVD
CEEEEEEECCEEEEEECCCCCCCCHHHHHHCCCCCEEEEECCCHHHCCCCCEEEEECCCC
TASGTIRLKAEFPNADRHLWPGMFVMVSLAPQTLIHALTVPVQAVQNGPEGKFLYVLDET
CCCCEEEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
GKVKPFSVEVRLVQEGVAVVEGKAITSGMHVVAEGAQNLRPGSAVTEASSIKTGAGAAGR
CCCCEEEEEEEEEECCCEEEECCCHHCCHHHEECCHHHCCCCCHHHHHHCCCCCCCCCCC
NS
CC
>Mature Secondary Structure
MWRNPSGAIDAKKKTSEPTPVITAVINQQNVPVQLAANGTVSAQQMVAVRPQLSAMISAV
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCHHHHEEECHHHHHHHHHH
HIREGQFVRKGEPLFTLDARTEDANVRRTEGQLAKSRADLRNAERNLERQRELFRQDFIS
EECCCCEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAALDVAENQVDALRAQLTVDEATAQANRIARGFSEITAPISGRSGAISVYQGSLVQPND
HHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEECCCC
ALVSITQIDPINVSFTLPERDFIPLQQAFAKGEVPVTVELNGPQKQTRTGRLIFIDNAVD
CEEEEEEECCEEEEEECCCCCCCCHHHHHHCCCCCEEEEECCCHHHCCCCCEEEEECCCC
TASGTIRLKAEFPNADRHLWPGMFVMVSLAPQTLIHALTVPVQAVQNGPEGKFLYVLDET
CCCCEEEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
GKVKPFSVEVRLVQEGVAVVEGKAITSGMHVVAEGAQNLRPGSAVTEASSIKTGAGAAGR
CCCCEEEEEEEEEECCCEEEECCCHHCCHHHEECCHHHCCCCCHHHHHHCCCCCCCCCCC
NS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA