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The map label for this gene is aroC

Identifier: 82703079

GI number: 82703079

Start: 2251312

End: 2252493

Strand: Reverse

Name: aroC

Synonym: Nmul_A1958

Alternate gene names: 82703079

Gene position: 2252493-2251312 (Counterclockwise)

Preceding gene: 82703081

Following gene: 82703074

Centisome position: 70.74

GC content: 55.92

Gene sequence:

>1182_bases
ATGTCCGGCAATACCTTTGGCAAACTGTTTTGCGTGACGTCTTTCGGGGAATCCCATGGCCCTGCCTTAGGATGCGTAGT
GGATGGTTGTCCCCCGGGAATGGAACTGTCCGCTGAGGATATCCAGCAGGATCTTGATCGGCGCAAGCCCGGCACCTCCC
GGCACGTAACCCAGCGGCGCGAGCCCGATACGGTGGAAATTCTTTCGGGCGTGTTCGAGGGCAAGACTACGGGAACACCG
ATCGCGTTGTTGATTCGCAACGAAGATCAACGCAGCAAGGACTACAGCAAAATCATGGATACTTTCCGCCCCGGGCACGC
GGACTATGTTTATTGGCAAAAATACGGCATACGCGATTACCGGGGAGGAGGACGTTCATCCGCGCGCGAAACCGCCGTGC
GGGTGGCGGCAGCAGCCATAGCAAAAAAATGGCTGCGTGCAAGATATGGAGTGGTAATAAGAGGTCATATGGCGCAACTG
GGACCTGTCGAGATTCCATTCAAACAATGGGAAGCAGTGGGTGAGAATCCCTTTTTTTCGGCTGACCCGGACATCGTGCC
CAGCCTGGAAGAATTCATGGACAAACTGCGGAAATCGGGCGACTCGGTGGGCGCCAGGATTCGTGTGGTTGCCGAAGGTG
TGCCCGTGGGGTGGGGCGAACCTGTATATGATCGCCTCGATGCCGAAATCGCCTATGGCATGATGAGCATCAACGCCGTT
AAAGGCGTCGAAATCGGAGCTGGATTTGCTTCTGTAAGTCAGAAGGGAACGGAGCACTCCGATGAAATCAGTCCCGGGGG
TTTTCTCAGCAATAATGCGGGAGGCATATTGGGCGGGATTTCCACCGGTCAGGATATCGTGGTGAATATCGCCGTCAAGC
CCACTTCAAGCATACGTCTGCCGCGCCGCTCAGTAGACAAGATGGGCAATCCGGCAATAGTGGAAACTCATGGAAGACAT
GACCCCTGTGTCGGTATCCGGGCTACGCCCATTGCGGAAGCAATGCTGGCGCTGGTATTGATGGACCATGCGCTGCGCAA
TAGGGCACAAAACGCGGATGTTGCGTGCACAACTCCAAAAATTCCCGGCCACACTGGCCCTAGGGAAGGTCAGGAAGAGG
GCCCGTCAGATAGCGAGCCAAAAGTGGAGTTTGCGGATGATCCCGAGCCGGATGAAGCGTGA

Upstream 100 bases:

>100_bases
CCTCGGCTACGAGTGGAACAGGAATGAAAGGCGTAGCGGAGGACGGTAAGGCTATGGGGATATGTTAAACTTCGAGCCTC
GATTTGGCTAGAAAAGTGAA

Downstream 100 bases:

>100_bases
AAGATGAGTGTGCTGCAAAAGATGGCGAGGGCGGGTGCGAGACCAAAAGCTTGTTTTCTTCATGCATTCCCGGCATGCCA
GAGCACGGCTTCCGTCACAT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSGNTFGKLFCVTSFGESHGPALGCVVDGCPPGMELSAEDIQQDLDRRKPGTSRHVTQRREPDTVEILSGVFEGKTTGTP
IALLIRNEDQRSKDYSKIMDTFRPGHADYVYWQKYGIRDYRGGGRSSARETAVRVAAAAIAKKWLRARYGVVIRGHMAQL
GPVEIPFKQWEAVGENPFFSADPDIVPSLEEFMDKLRKSGDSVGARIRVVAEGVPVGWGEPVYDRLDAEIAYGMMSINAV
KGVEIGAGFASVSQKGTEHSDEISPGGFLSNNAGGILGGISTGQDIVVNIAVKPTSSIRLPRRSVDKMGNPAIVETHGRH
DPCVGIRATPIAEAMLALVLMDHALRNRAQNADVACTTPKIPGHTGPREGQEEGPSDSEPKVEFADDPEPDEA

Sequences:

>Translated_393_residues
MSGNTFGKLFCVTSFGESHGPALGCVVDGCPPGMELSAEDIQQDLDRRKPGTSRHVTQRREPDTVEILSGVFEGKTTGTP
IALLIRNEDQRSKDYSKIMDTFRPGHADYVYWQKYGIRDYRGGGRSSARETAVRVAAAAIAKKWLRARYGVVIRGHMAQL
GPVEIPFKQWEAVGENPFFSADPDIVPSLEEFMDKLRKSGDSVGARIRVVAEGVPVGWGEPVYDRLDAEIAYGMMSINAV
KGVEIGAGFASVSQKGTEHSDEISPGGFLSNNAGGILGGISTGQDIVVNIAVKPTSSIRLPRRSVDKMGNPAIVETHGRH
DPCVGIRATPIAEAMLALVLMDHALRNRAQNADVACTTPKIPGHTGPREGQEEGPSDSEPKVEFADDPEPDEA
>Mature_392_residues
SGNTFGKLFCVTSFGESHGPALGCVVDGCPPGMELSAEDIQQDLDRRKPGTSRHVTQRREPDTVEILSGVFEGKTTGTPI
ALLIRNEDQRSKDYSKIMDTFRPGHADYVYWQKYGIRDYRGGGRSSARETAVRVAAAAIAKKWLRARYGVVIRGHMAQLG
PVEIPFKQWEAVGENPFFSADPDIVPSLEEFMDKLRKSGDSVGARIRVVAEGVPVGWGEPVYDRLDAEIAYGMMSINAVK
GVEIGAGFASVSQKGTEHSDEISPGGFLSNNAGGILGGISTGQDIVVNIAVKPTSSIRLPRRSVDKMGNPAIVETHGRHD
PCVGIRATPIAEAMLALVLMDHALRNRAQNADVACTTPKIPGHTGPREGQEEGPSDSEPKVEFADDPEPDEA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=360, Percent_Identity=65, Blast_Score=471, Evalue=1e-134,
Organism=Saccharomyces cerevisiae, GI6321290, Length=369, Percent_Identity=43.0894308943089, Blast_Score=285, Evalue=9e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_NITMU (Q2Y7L8)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_412645.1
- HSSP:   P63611
- ProteinModelPortal:   Q2Y7L8
- SMR:   Q2Y7L8
- STRING:   Q2Y7L8
- GeneID:   3785136
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1958
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   Q2Y7L8
- ProtClustDB:   PRK05382
- BioCyc:   NMUL323848:NMUL_A1958-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 42349; Mature: 42218

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNTFGKLFCVTSFGESHGPALGCVVDGCPPGMELSAEDIQQDLDRRKPGTSRHVTQRR
CCCCCEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHCC
EPDTVEILSGVFEGKTTGTPIALLIRNEDQRSKDYSKIMDTFRPGHADYVYWQKYGIRDY
CCCHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
RGGGRSSARETAVRVAAAAIAKKWLRARYGVVIRGHMAQLGPVEIPFKQWEAVGENPFFS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHCCCCCCCC
ADPDIVPSLEEFMDKLRKSGDSVGARIRVVAEGVPVGWGEPVYDRLDAEIAYGMMSINAV
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHEECCC
KGVEIGAGFASVSQKGTEHSDEISPGGFLSNNAGGILGGISTGQDIVVNIAVKPTSSIRL
CCEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEECCCCCCCC
PRRSVDKMGNPAIVETHGRHDPCVGIRATPIAEAMLALVLMDHALRNRAQNADVACTTPK
CHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
IPGHTGPREGQEEGPSDSEPKVEFADDPEPDEA
CCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCC
>Mature Secondary Structure 
SGNTFGKLFCVTSFGESHGPALGCVVDGCPPGMELSAEDIQQDLDRRKPGTSRHVTQRR
CCCCEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHCC
EPDTVEILSGVFEGKTTGTPIALLIRNEDQRSKDYSKIMDTFRPGHADYVYWQKYGIRDY
CCCHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
RGGGRSSARETAVRVAAAAIAKKWLRARYGVVIRGHMAQLGPVEIPFKQWEAVGENPFFS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHCCCCCCCC
ADPDIVPSLEEFMDKLRKSGDSVGARIRVVAEGVPVGWGEPVYDRLDAEIAYGMMSINAV
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHEECCC
KGVEIGAGFASVSQKGTEHSDEISPGGFLSNNAGGILGGISTGQDIVVNIAVKPTSSIRL
CCEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEECCCCCCCC
PRRSVDKMGNPAIVETHGRHDPCVGIRATPIAEAMLALVLMDHALRNRAQNADVACTTPK
CHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
IPGHTGPREGQEEGPSDSEPKVEFADDPEPDEA
CCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA