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The map label for this gene is ctaD [H]

Identifier: 82702899

GI number: 82702899

Start: 2029010

End: 2030599

Strand: Reverse

Name: ctaD [H]

Synonym: Nmul_A1776

Alternate gene names: 82702899

Gene position: 2030599-2029010 (Counterclockwise)

Preceding gene: 82702900

Following gene: 82702898

Centisome position: 63.77

GC content: 55.97

Gene sequence:

>1590_bases
ATGGCAGCAATACCCGATCACGATGTCGTGCATGGCGCCGAGCACGCGCACGACCACCCCACCGGCCTGATGCGGTGGCT
GACTACCACGAATCACAAGGATATCGGTACGCTTTATCTCTGGTTCAGCTTCATCATGTTCCTCACGGGGGGCGTGATGG
CGCTGACCATCCGGGCCGAGTTATTTCAGCCAGGTATACAGATCGTCAATCCCGAATTTTTTAACCAGCTCACCACCATG
CACGGCTTGGTGATGGTGTTCGGCGCCATCATGCCGGCCTTCGTCGGTTTTGCCAACTGGCAGATACCGATGATGATCGG
CGCTCCCGACATGGCCTTCGCGCGAATGAACAACTGGAGCTTCTGGCTGCTGCCTCCTGCGGCATTGTTGCTCATCGCTT
CTTTCTTCGTGCCCGGCGGCGCTGCTGCCGGGGGCTGGACTTTCTATCCTCCGCTGTCGGTCCAAATGGGCATCGGGATG
GACATGATGATTTTCGCCATTCATATACTTGGCGCCTCTTCCATCATGGGCTCGATCAACATCATCACCACCATTCTCAA
CATGCGCGCCCCTGGCATGACCCTGATGAAGATGCCCATGTTCGTGTGGACCTGGCTGATTACCGCTTATCTGCTGGTGC
TGGTCATGCCGGTGCTCGCCGGTGTGGTGACCATGCTGCTGACCGACCGTAACTTCGGCACCAATTTCTTCAATGCGGCG
GGTGGGGGTGATCCCGTGCTGTTCCAGCATGTTTTCTGGTTCTTCGGTCACCCGGAAGTCTACATCATGATCCTGCCGTC
ATTCGGCATTGTCTCCGAGGTAATTCCCGCTTTTTCCCGCAAACCGCTGTTCGGTTATTCCTCGATGGTGTATGCAACTG
CTTCCATCGCCATTCTTTCCTGCATCGTCTGGGCGCACCATATGTTCACCGCAGGCATGCCTGTAACCGGACAACTGTTC
TTCATGTACGGCACCATGCTGATCGCGGTTCCGACGGGCGTGAAGGTATTCAACTGGACCGCCACGATGTGGCGTGGTTC
CATGACCTTTGAAACACCCATGCTGTTTTCCATCGGCTTCATTTTCCTGTTCGTCATCGGAGGTTTTAGCGGCGTGGTCT
GCGCTATTGTCCCGATCGATGTGCAGGTGCAGGATACCTACTATGTGATCGCGCACTTCCACTACGTGCTGGTATCCGGT
TCGCTCTTTGCCATCTTCGCCGGAGCGTACTACTGGCTGCCCAAGTGGACGGGTCACATGTATGACGAGACGTTGGGCAA
ATGGCATTTCTGGTTGTCGATGTTCTTCTTCAACCTCACCTTCTTCGTGCAGCACTTCCTGGGATTGGCCGGCATGCCGC
GCCGCATCCCCGACTATGCGCTGCAATTTGCGGACTTCAACATGATTTCCAGCATAGGAGCATTCGGATTCGGTACGACC
CAATTGTTGTTCCTCTATGTAGTGCTGAAGTGCATTCGCGGAGGAGCAAAGGCGCCCCAGAAACCGTGGGAGGGTGCAAA
AACACTGGAGTGGACCCTGCCCTCGCCGGCGCCGTATCACAGCTTTGAAACGCCGCCGCTCGTGAAGTAG

Upstream 100 bases:

>100_bases
GTGATCACCTACCAGCGCAATTCCTTCGGCAATTCGACGGGCGATGCCGTCCAGCCATCCGAAATCAATCAACACAGATA
ATAGCCTCAAGGAGGAAACC

Downstream 100 bases:

>100_bases
TCCGCTAATCGATATAAACAGGAGATCGTCATGTCGAAAAATATGGATATGCCGCAACCCGTAAGCCTGTCGGAAGACGA
GGAGATCGAGAGGAAGCTCT

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MAAIPDHDVVHGAEHAHDHPTGLMRWLTTTNHKDIGTLYLWFSFIMFLTGGVMALTIRAELFQPGIQIVNPEFFNQLTTM
HGLVMVFGAIMPAFVGFANWQIPMMIGAPDMAFARMNNWSFWLLPPAALLLIASFFVPGGAAAGGWTFYPPLSVQMGIGM
DMMIFAIHILGASSIMGSINIITTILNMRAPGMTLMKMPMFVWTWLITAYLLVLVMPVLAGVVTMLLTDRNFGTNFFNAA
GGGDPVLFQHVFWFFGHPEVYIMILPSFGIVSEVIPAFSRKPLFGYSSMVYATASIAILSCIVWAHHMFTAGMPVTGQLF
FMYGTMLIAVPTGVKVFNWTATMWRGSMTFETPMLFSIGFIFLFVIGGFSGVVCAIVPIDVQVQDTYYVIAHFHYVLVSG
SLFAIFAGAYYWLPKWTGHMYDETLGKWHFWLSMFFFNLTFFVQHFLGLAGMPRRIPDYALQFADFNMISSIGAFGFGTT
QLLFLYVVLKCIRGGAKAPQKPWEGAKTLEWTLPSPAPYHSFETPPLVK

Sequences:

>Translated_529_residues
MAAIPDHDVVHGAEHAHDHPTGLMRWLTTTNHKDIGTLYLWFSFIMFLTGGVMALTIRAELFQPGIQIVNPEFFNQLTTM
HGLVMVFGAIMPAFVGFANWQIPMMIGAPDMAFARMNNWSFWLLPPAALLLIASFFVPGGAAAGGWTFYPPLSVQMGIGM
DMMIFAIHILGASSIMGSINIITTILNMRAPGMTLMKMPMFVWTWLITAYLLVLVMPVLAGVVTMLLTDRNFGTNFFNAA
GGGDPVLFQHVFWFFGHPEVYIMILPSFGIVSEVIPAFSRKPLFGYSSMVYATASIAILSCIVWAHHMFTAGMPVTGQLF
FMYGTMLIAVPTGVKVFNWTATMWRGSMTFETPMLFSIGFIFLFVIGGFSGVVCAIVPIDVQVQDTYYVIAHFHYVLVSG
SLFAIFAGAYYWLPKWTGHMYDETLGKWHFWLSMFFFNLTFFVQHFLGLAGMPRRIPDYALQFADFNMISSIGAFGFGTT
QLLFLYVVLKCIRGGAKAPQKPWEGAKTLEWTLPSPAPYHSFETPPLVK
>Mature_528_residues
AAIPDHDVVHGAEHAHDHPTGLMRWLTTTNHKDIGTLYLWFSFIMFLTGGVMALTIRAELFQPGIQIVNPEFFNQLTTMH
GLVMVFGAIMPAFVGFANWQIPMMIGAPDMAFARMNNWSFWLLPPAALLLIASFFVPGGAAAGGWTFYPPLSVQMGIGMD
MMIFAIHILGASSIMGSINIITTILNMRAPGMTLMKMPMFVWTWLITAYLLVLVMPVLAGVVTMLLTDRNFGTNFFNAAG
GGDPVLFQHVFWFFGHPEVYIMILPSFGIVSEVIPAFSRKPLFGYSSMVYATASIAILSCIVWAHHMFTAGMPVTGQLFF
MYGTMLIAVPTGVKVFNWTATMWRGSMTFETPMLFSIGFIFLFVIGGFSGVVCAIVPIDVQVQDTYYVIAHFHYVLVSGS
LFAIFAGAYYWLPKWTGHMYDETLGKWHFWLSMFFFNLTFFVQHFLGLAGMPRRIPDYALQFADFNMISSIGAFGFGTTQ
LLFLYVVLKCIRGGAKAPQKPWEGAKTLEWTLPSPAPYHSFETPPLVK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=510, Percent_Identity=51.3725490196078, Blast_Score=464, Evalue=1e-130,
Organism=Escherichia coli, GI1786634, Length=514, Percent_Identity=40.272373540856, Blast_Score=354, Evalue=8e-99,
Organism=Saccharomyces cerevisiae, GI6226519, Length=530, Percent_Identity=46.7924528301887, Blast_Score=466, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6226524, Length=321, Percent_Identity=50.4672897196262, Blast_Score=317, Evalue=4e-87,
Organism=Saccharomyces cerevisiae, GI6226523, Length=249, Percent_Identity=46.9879518072289, Blast_Score=205, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59022; Mature: 58891

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
6.8 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
6.6 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAIPDHDVVHGAEHAHDHPTGLMRWLTTTNHKDIGTLYLWFSFIMFLTGGVMALTIRAE
CCCCCCCCHHCCCHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHH
LFQPGIQIVNPEFFNQLTTMHGLVMVFGAIMPAFVGFANWQIPMMIGAPDMAFARMNNWS
HHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHEECCCE
FWLLPPAALLLIASFFVPGGAAAGGWTFYPPLSVQMGIGMDMMIFAIHILGASSIMGSIN
EEECCHHHHHHHHHHHCCCCCCCCCCEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
IITTILNMRAPGMTLMKMPMFVWTWLITAYLLVLVMPVLAGVVTMLLTDRNFGTNFFNAA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GGGDPVLFQHVFWFFGHPEVYIMILPSFGIVSEVIPAFSRKPLFGYSSMVYATASIAILS
CCCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
CIVWAHHMFTAGMPVTGQLFFMYGTMLIAVPTGVKVFNWTATMWRGSMTFETPMLFSIGF
HHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCEEEEEEHHHHCCCCCCCCHHHHHHHH
IFLFVIGGFSGVVCAIVPIDVQVQDTYYVIAHFHYVLVSGSLFAIFAGAYYWLPKWTGHM
HHHHHHHCCCCEEEEEEEEEEEECCCEEEHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCH
YDETLGKWHFWLSMFFFNLTFFVQHFLGLAGMPRRIPDYALQFADFNMISSIGAFGFGTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHH
QLLFLYVVLKCIRGGAKAPQKPWEGAKTLEWTLPSPAPYHSFETPPLVK
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AAIPDHDVVHGAEHAHDHPTGLMRWLTTTNHKDIGTLYLWFSFIMFLTGGVMALTIRAE
CCCCCCCHHCCCHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHH
LFQPGIQIVNPEFFNQLTTMHGLVMVFGAIMPAFVGFANWQIPMMIGAPDMAFARMNNWS
HHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHEECCCE
FWLLPPAALLLIASFFVPGGAAAGGWTFYPPLSVQMGIGMDMMIFAIHILGASSIMGSIN
EEECCHHHHHHHHHHHCCCCCCCCCCEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
IITTILNMRAPGMTLMKMPMFVWTWLITAYLLVLVMPVLAGVVTMLLTDRNFGTNFFNAA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GGGDPVLFQHVFWFFGHPEVYIMILPSFGIVSEVIPAFSRKPLFGYSSMVYATASIAILS
CCCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
CIVWAHHMFTAGMPVTGQLFFMYGTMLIAVPTGVKVFNWTATMWRGSMTFETPMLFSIGF
HHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCEEEEEEHHHHCCCCCCCCHHHHHHHH
IFLFVIGGFSGVVCAIVPIDVQVQDTYYVIAHFHYVLVSGSLFAIFAGAYYWLPKWTGHM
HHHHHHHCCCCEEEEEEEEEEEECCCEEEHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCH
YDETLGKWHFWLSMFFFNLTFFVQHFLGLAGMPRRIPDYALQFADFNMISSIGAFGFGTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHH
QLLFLYVVLKCIRGGAKAPQKPWEGAKTLEWTLPSPAPYHSFETPPLVK
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]