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The map label for this gene is atpB

Identifier: 82702781

GI number: 82702781

Start: 1895790

End: 1896545

Strand: Reverse

Name: atpB

Synonym: Nmul_A1657

Alternate gene names: 82702781

Gene position: 1896545-1895790 (Counterclockwise)

Preceding gene: 82702782

Following gene: 82702780

Centisome position: 59.56

GC content: 52.91

Gene sequence:

>756_bases
ATGCATATTAGCCCCGATCAGCTCATCTTCTGGGAATATGGTTTCGTGAAACTTAACGGCACCATCATTTACACATGGCT
GCTGATGCTGTTGCTTGCGGTCGGATCGAAGACTATTACTAAGCGACTGTCTCGCGGAGAGGAACGCTCCCGATGGCAAA
ATCTGCTGGAAGTCATCATTATTACGATACAAAAACAGATCAGCGAGGTAGGCCTTCGCCAGCCGCGCACCTACCTTCCA
TTTCTGGGGACTCTGTTTGTCTTTGTCGCCGTGGCAAACCTTTTTGCCGTCTTTCCCGGTTACGAGCCCCCGACCGGATC
GCTTTCCACAACTGTTGCACTGGCGATCTGCGTATTCGTTGCTGTCCCGTTTTATGGAATCAGGGAGCAAGGCCTGCGCC
GCTATTTGCAGTCCTATCTCAAGCCGGTGCCGCTCTTGCTCCCGTTCAATATCCTGGGGGAGTTCACACGCACGCTGGCT
CTTGCCGTGCGGCTGTTCGGCAACATGATGAGCGGGACCATGATCCTCGCTATCATGCTGATCATCACACCCTTTATTTT
CCCCGTGGTCATGGGAGTCCTCCACCTGTTGATAGGTGGCGTGCAAGCTTATATCTTCAGCATCCTGGCCACGGTCTACA
TCGCGGCCGCAACTTCCGATAATGGGGAAAATGCGGGAGCATCAGATGATGAAGGTGGTGAAGACGCCAAAAGCGCATGC
GCAGCTGGTGGGAAAATCTGCAAACATAAACCCTAA

Upstream 100 bases:

>100_bases
TAGTGGCAACCCAATTTCTGCCCACGCCGTTATCCCCATCGCTGGTCCGAATGGGGCGACCGGGAGGAAGTGCGATATCC
GCCGGAGAGCATTAGCAGTT

Downstream 100 bases:

>100_bases
GGAGCAAGCATGGACAGCATTACCCTAATCGCAATCATATCCATCCTGACGGCTGGTCTGACTATCAGTATTGGCGTGAT
CGGGCCCGCGCTGGGTGAAG

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MHISPDQLIFWEYGFVKLNGTIIYTWLLMLLLAVGSKTITKRLSRGEERSRWQNLLEVIIITIQKQISEVGLRQPRTYLP
FLGTLFVFVAVANLFAVFPGYEPPTGSLSTTVALAICVFVAVPFYGIREQGLRRYLQSYLKPVPLLLPFNILGEFTRTLA
LAVRLFGNMMSGTMILAIMLIITPFIFPVVMGVLHLLIGGVQAYIFSILATVYIAAATSDNGENAGASDDEGGEDAKSAC
AAGGKICKHKP

Sequences:

>Translated_251_residues
MHISPDQLIFWEYGFVKLNGTIIYTWLLMLLLAVGSKTITKRLSRGEERSRWQNLLEVIIITIQKQISEVGLRQPRTYLP
FLGTLFVFVAVANLFAVFPGYEPPTGSLSTTVALAICVFVAVPFYGIREQGLRRYLQSYLKPVPLLLPFNILGEFTRTLA
LAVRLFGNMMSGTMILAIMLIITPFIFPVVMGVLHLLIGGVQAYIFSILATVYIAAATSDNGENAGASDDEGGEDAKSAC
AAGGKICKHKP
>Mature_251_residues
MHISPDQLIFWEYGFVKLNGTIIYTWLLMLLLAVGSKTITKRLSRGEERSRWQNLLEVIIITIQKQISEVGLRQPRTYLP
FLGTLFVFVAVANLFAVFPGYEPPTGSLSTTVALAICVFVAVPFYGIREQGLRRYLQSYLKPVPLLLPFNILGEFTRTLA
LAVRLFGNMMSGTMILAIMLIITPFIFPVVMGVLHLLIGGVQAYIFSILATVYIAAATSDNGENAGASDDEGGEDAKSAC
AAGGKICKHKP

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=212, Percent_Identity=24.0566037735849, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_NITMU (Q2Y8G6)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_412347.1
- ProteinModelPortal:   Q2Y8G6
- SMR:   Q2Y8G6
- STRING:   Q2Y8G6
- GeneID:   3785599
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1657
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   PFIFPVV
- PhylomeDB:   Q2Y8G6
- ProtClustDB:   PRK05815
- BioCyc:   NMUL323848:NMUL_A1657-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR017692
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR03306
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 27564; Mature: 27564

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10c46c80)-; HASH(0x13b8187c)-; HASH(0x13c595f8)-; HASH(0x132b298c)-; HASH(0x1404d74c)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHISPDQLIFWEYGFVKLNGTIIYTWLLMLLLAVGSKTITKRLSRGEERSRWQNLLEVII
CCCCCCCEEEEECCEEEECCCHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHH
ITIQKQISEVGLRQPRTYLPFLGTLFVFVAVANLFAVFPGYEPPTGSLSTTVALAICVFV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AVPFYGIREQGLRRYLQSYLKPVPLLLPFNILGEFTRTLALAVRLFGNMMSGTMILAIML
HHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IITPFIFPVVMGVLHLLIGGVQAYIFSILATVYIAAATSDNGENAGASDDEGGEDAKSAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
AAGGKICKHKP
HCCCCCCCCCH
>Mature Secondary Structure
MHISPDQLIFWEYGFVKLNGTIIYTWLLMLLLAVGSKTITKRLSRGEERSRWQNLLEVII
CCCCCCCEEEEECCEEEECCCHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHH
ITIQKQISEVGLRQPRTYLPFLGTLFVFVAVANLFAVFPGYEPPTGSLSTTVALAICVFV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AVPFYGIREQGLRRYLQSYLKPVPLLLPFNILGEFTRTLALAVRLFGNMMSGTMILAIML
HHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IITPFIFPVVMGVLHLLIGGVQAYIFSILATVYIAAATSDNGENAGASDDEGGEDAKSAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
AAGGKICKHKP
HCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA