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The map label for this gene is atpA2

Identifier: 82702778

GI number: 82702778

Start: 1892977

End: 1894512

Strand: Reverse

Name: atpA2

Synonym: Nmul_A1654

Alternate gene names: 82702778

Gene position: 1894512-1892977 (Counterclockwise)

Preceding gene: 82702779

Following gene: 82702777

Centisome position: 59.5

GC content: 56.97

Gene sequence:

>1536_bases
GTGAATCAAGATCGATTGCGAGACGTTTTTGATGGCGCTTTTTCCCGGATTGCTCTCGCGCGGAAAATCGTGACTCCCCG
ACTCATGCTGAAGGAGATCGGGGTAATTAAGAGCATTGGTACTGGCATAGCGAAGGTTTCCGGCCTTCCCGGCACGTGCT
TCGAGGAGGTGCTCAAGTTTCCCGGCGGCTATGGCATTGCATTTAATATCGAAGAAGAGGAAATCGGGGTGATCCTGCTG
GGTGATCATTCTCACCTGCGTGCAGGAGATGAAGTGGAGCGCAGGGGACACGTAATGGATGTGCCGGTGGGCGACGCGTT
GATCGGAAGGATAGTCAATCCGCTGGGCCGGGCGCTCGATGGCGAAGCTCCGGTAATATCCTCGCGCCGTATGCCAATCG
AACGTCCCGCTCCCCAGATTATGGATCGGGCTCCTGTCACAGTGCCGCTTCAGACGGGCATCAAGGTCATCGATGCACTG
ATTCCTGTAGGGCGGGGGCAGCGCGAACTGATACTGGGCGACCGGCAGACGGGCAAGAGCGCTATAGCACTCGACACCAT
ACTGAATCAGAAAGACGAGAACGTGGTGTGCATCTACTGCGCCATCGGGCAGCAAGCATCGAGTGTTGCCAAGGTAGTGG
CTGCGCTGCAGGAAAATGACGCTCTGAGCTATACAGTTGTGGTAGTAACCGAAGGCAATGACCCGCCGGGGCTGATCTAT
GTTGCCCCCTATGCCGCGACTGCTATCGGAGAATACTTCATGGAGCAGGGCCGGGACGTTTTGATCGTTTACGATGACCT
TTCGCACCACGCTCGCGCCTACCGTGAACTTTCGCTGCTGATGCGGCGCCCCCCTGGACGCGAAGCCTATCCCGGAGACA
TCTTTTACATCCACTCACGCTTGCTGGAGCGCGCTACGCATCTGCGCCCCGAACTCGGCGGCGGTTCCCTGACCGCCTTG
CCGATCGTAGAAACAGAAGCGGAGGACATCGCAGCATATATTCCAACCAATCTGATCTCGATTACCGACGGGCAGATTTA
CCTTTCACCCACATTGTTTCAACTTGGAATACTGCCCGCCATCGACGTTGGCAAATCGGTTTCGCGGGTGGGAGGCAAGG
CGCAGCGGCCTGTGTACCGGGCCGCTACCGGCGAGCTGAGGCTGGATTATTCCCAGTTCAGCGAACTGGAAACATTTACA
CGCTTCGGGGGACGCCTCGATGAGCGTACCCGTACCGTTATCGAGCATGGCCGGCGTATTCGTGCCTGTTTGCAGCAGCC
AGAGTCCAGCCCGGTTTCCGTCTCAGAGCAGATCATTCTGCTGCTGGCATTGACCGCAAAACTATTCGACGAGGTACCGC
TGGAAAACATGGGGGAGGCGGAGCGGGCGGTGAGGGCAGTAGTGTTGAATATACCTCCCGAACTGCTTGCACGTATGGAA
GCCAACGAAAGCCTGAACGATGCAGATCGCCATGCACTTTTGTGGCATGCAAGCACTGCGCTGGATGGGTTAGGCTCAGC
ACATGCGAAAGCCTAA

Upstream 100 bases:

>100_bases
AAAGACGGACGACCCTTGTCAATCGAGACTGCACGAATGTCACACGGGGCGCTAGTAGGCAGCAACTCAATTGATCCTGG
CAGAGTAGGTGGCGGCTAGC

Downstream 100 bases:

>100_bases
GCGCAAGTGGTGGAAGCTGCAACCGCTGTTGAATTGGAACAGAGATCATGAGCGATACCACTGCCAGCATACGCCGCAAG
ATCGAGGGTGTGAAAGATCT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 2; F-ATPase subunit alpha 2

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MNQDRLRDVFDGAFSRIALARKIVTPRLMLKEIGVIKSIGTGIAKVSGLPGTCFEEVLKFPGGYGIAFNIEEEEIGVILL
GDHSHLRAGDEVERRGHVMDVPVGDALIGRIVNPLGRALDGEAPVISSRRMPIERPAPQIMDRAPVTVPLQTGIKVIDAL
IPVGRGQRELILGDRQTGKSAIALDTILNQKDENVVCIYCAIGQQASSVAKVVAALQENDALSYTVVVVTEGNDPPGLIY
VAPYAATAIGEYFMEQGRDVLIVYDDLSHHARAYRELSLLMRRPPGREAYPGDIFYIHSRLLERATHLRPELGGGSLTAL
PIVETEAEDIAAYIPTNLISITDGQIYLSPTLFQLGILPAIDVGKSVSRVGGKAQRPVYRAATGELRLDYSQFSELETFT
RFGGRLDERTRTVIEHGRRIRACLQQPESSPVSVSEQIILLLALTAKLFDEVPLENMGEAERAVRAVVLNIPPELLARME
ANESLNDADRHALLWHASTALDGLGSAHAKA

Sequences:

>Translated_511_residues
MNQDRLRDVFDGAFSRIALARKIVTPRLMLKEIGVIKSIGTGIAKVSGLPGTCFEEVLKFPGGYGIAFNIEEEEIGVILL
GDHSHLRAGDEVERRGHVMDVPVGDALIGRIVNPLGRALDGEAPVISSRRMPIERPAPQIMDRAPVTVPLQTGIKVIDAL
IPVGRGQRELILGDRQTGKSAIALDTILNQKDENVVCIYCAIGQQASSVAKVVAALQENDALSYTVVVVTEGNDPPGLIY
VAPYAATAIGEYFMEQGRDVLIVYDDLSHHARAYRELSLLMRRPPGREAYPGDIFYIHSRLLERATHLRPELGGGSLTAL
PIVETEAEDIAAYIPTNLISITDGQIYLSPTLFQLGILPAIDVGKSVSRVGGKAQRPVYRAATGELRLDYSQFSELETFT
RFGGRLDERTRTVIEHGRRIRACLQQPESSPVSVSEQIILLLALTAKLFDEVPLENMGEAERAVRAVVLNIPPELLARME
ANESLNDADRHALLWHASTALDGLGSAHAKA
>Mature_511_residues
MNQDRLRDVFDGAFSRIALARKIVTPRLMLKEIGVIKSIGTGIAKVSGLPGTCFEEVLKFPGGYGIAFNIEEEEIGVILL
GDHSHLRAGDEVERRGHVMDVPVGDALIGRIVNPLGRALDGEAPVISSRRMPIERPAPQIMDRAPVTVPLQTGIKVIDAL
IPVGRGQRELILGDRQTGKSAIALDTILNQKDENVVCIYCAIGQQASSVAKVVAALQENDALSYTVVVVTEGNDPPGLIY
VAPYAATAIGEYFMEQGRDVLIVYDDLSHHARAYRELSLLMRRPPGREAYPGDIFYIHSRLLERATHLRPELGGGSLTAL
PIVETEAEDIAAYIPTNLISITDGQIYLSPTLFQLGILPAIDVGKSVSRVGGKAQRPVYRAATGELRLDYSQFSELETFT
RFGGRLDERTRTVIEHGRRIRACLQQPESSPVSVSEQIILLLALTAKLFDEVPLENMGEAERAVRAVVLNIPPELLARME
ANESLNDADRHALLWHASTALDGLGSAHAKA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=467, Percent_Identity=46.6809421841542, Blast_Score=438, Evalue=1e-123,
Organism=Homo sapiens, GI4757810, Length=467, Percent_Identity=46.6809421841542, Blast_Score=438, Evalue=1e-123,
Organism=Homo sapiens, GI32189394, Length=375, Percent_Identity=26.1333333333333, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI19913426, Length=301, Percent_Identity=27.5747508305648, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI19913428, Length=302, Percent_Identity=27.8145695364238, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1790172, Length=466, Percent_Identity=44.8497854077253, Blast_Score=423, Evalue=1e-119,
Organism=Escherichia coli, GI1790170, Length=358, Percent_Identity=27.6536312849162, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788251, Length=269, Percent_Identity=31.5985130111524, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71988063, Length=432, Percent_Identity=48.3796296296296, Blast_Score=431, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI71988080, Length=432, Percent_Identity=48.3796296296296, Blast_Score=431, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI71988074, Length=432, Percent_Identity=44.9074074074074, Blast_Score=380, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17510931, Length=315, Percent_Identity=27.6190476190476, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17570191, Length=360, Percent_Identity=27.2222222222222, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI25144756, Length=352, Percent_Identity=25.5681818181818, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319370, Length=467, Percent_Identity=46.2526766595289, Blast_Score=429, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6322581, Length=373, Percent_Identity=27.0777479892761, Blast_Score=117, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6319603, Length=293, Percent_Identity=29.6928327645051, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24658560, Length=427, Percent_Identity=48.9461358313817, Blast_Score=435, Evalue=1e-122,
Organism=Drosophila melanogaster, GI281361666, Length=319, Percent_Identity=26.9592476489028, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24646341, Length=319, Percent_Identity=26.9592476489028, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17136796, Length=319, Percent_Identity=26.9592476489028, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24638766, Length=375, Percent_Identity=25.3333333333333, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28574560, Length=357, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24583988, Length=288, Percent_Identity=25.6944444444444, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583986, Length=288, Percent_Identity=25.6944444444444, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583984, Length=288, Percent_Identity=25.6944444444444, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583992, Length=288, Percent_Identity=26.0416666666667, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA2_NITMU (Q2Y8G9)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_412344.1
- ProteinModelPortal:   Q2Y8G9
- SMR:   Q2Y8G9
- STRING:   Q2Y8G9
- GeneID:   3785596
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1654
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   NVLCVYC
- ProtClustDB:   PRK13343
- BioCyc:   NMUL323848:NMUL_A1654-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR017710
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR03324
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55674; Mature: 55674

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQDRLRDVFDGAFSRIALARKIVTPRLMLKEIGVIKSIGTGIAKVSGLPGTCFEEVLKF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHC
PGGYGIAFNIEEEEIGVILLGDHSHLRAGDEVERRGHVMDVPVGDALIGRIVNPLGRALD
CCCCEEEEEECHHHEEEEEECCCCCCCCCCHHHHCCCEEECCCCHHHHHHHHHHHHHHCC
GEAPVISSRRMPIERPAPQIMDRAPVTVPLQTGIKVIDALIPVGRGQRELILGDRQTGKS
CCCCEECCCCCCCCCCCHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCCEEEECCCCCCCH
AIALDTILNQKDENVVCIYCAIGQQASSVAKVVAALQENDALSYTVVVVTEGNDPPGLIY
HHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEE
VAPYAATAIGEYFMEQGRDVLIVYDDLSHHARAYRELSLLMRRPPGREAYPGDIFYIHSR
ECCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LLERATHLRPELGGGSLTALPIVETEAEDIAAYIPTNLISITDGQIYLSPTLFQLGILPA
HHHHHHHCCCCCCCCCEEEEEEEECCHHHHHHHCCCCEEEEECCEEEECCHHHHHCCCCH
IDVGKSVSRVGGKAQRPVYRAATGELRLDYSQFSELETFTRFGGRLDERTRTVIEHGRRI
HHCCCHHHHHCCCCCCCEEEECCCCEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RACLQQPESSPVSVSEQIILLLALTAKLFDEVPLENMGEAERAVRAVVLNIPPELLARME
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEEECCCHHHHHHHH
ANESLNDADRHALLWHASTALDGLGSAHAKA
CCCCCCCCCCEEEEEECHHHHHCCCCCCCCC
>Mature Secondary Structure
MNQDRLRDVFDGAFSRIALARKIVTPRLMLKEIGVIKSIGTGIAKVSGLPGTCFEEVLKF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHC
PGGYGIAFNIEEEEIGVILLGDHSHLRAGDEVERRGHVMDVPVGDALIGRIVNPLGRALD
CCCCEEEEEECHHHEEEEEECCCCCCCCCCHHHHCCCEEECCCCHHHHHHHHHHHHHHCC
GEAPVISSRRMPIERPAPQIMDRAPVTVPLQTGIKVIDALIPVGRGQRELILGDRQTGKS
CCCCEECCCCCCCCCCCHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCCEEEECCCCCCCH
AIALDTILNQKDENVVCIYCAIGQQASSVAKVVAALQENDALSYTVVVVTEGNDPPGLIY
HHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEE
VAPYAATAIGEYFMEQGRDVLIVYDDLSHHARAYRELSLLMRRPPGREAYPGDIFYIHSR
ECCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LLERATHLRPELGGGSLTALPIVETEAEDIAAYIPTNLISITDGQIYLSPTLFQLGILPA
HHHHHHHCCCCCCCCCEEEEEEEECCHHHHHHHCCCCEEEEECCEEEECCHHHHHCCCCH
IDVGKSVSRVGGKAQRPVYRAATGELRLDYSQFSELETFTRFGGRLDERTRTVIEHGRRI
HHCCCHHHHHCCCCCCCEEEECCCCEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RACLQQPESSPVSVSEQIILLLALTAKLFDEVPLENMGEAERAVRAVVLNIPPELLARME
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEEECCCHHHHHHHH
ANESLNDADRHALLWHASTALDGLGSAHAKA
CCCCCCCCCCEEEEEECHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA