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The map label for this gene is ubiB [H]

Identifier: 82702725

GI number: 82702725

Start: 1831254

End: 1833029

Strand: Reverse

Name: ubiB [H]

Synonym: Nmul_A1598

Alternate gene names: 82702725

Gene position: 1833029-1831254 (Counterclockwise)

Preceding gene: 82702726

Following gene: 82702724

Centisome position: 57.57

GC content: 58.22

Gene sequence:

>1776_bases
ATGCTCTGGCAGGCAATGACCGCAGCGCGGGATCTCGGGCGCCTGCACGAGATTGCTTCAATCCTCATACGGCATGGTTT
CGGGGATGTGGTGCGCCGGCTCGGGTTTGCCCACGCGCTGGAGCGCGCGGGACGCGCATTGCGCTGGAGCGAGGCCACCG
AACTGGCACAGCTTGAACCTCAGGCGAGTGTGCGGCGCGCCATGGAGGAGATGGGCCCTACCTTCGTCAAGCTCGGCCAG
ATTCTGGCAACACGCGTTGACCTTTTCGATCCCGAATGGATCGCTGAATTCAGCAAGCTGCAGGACAGTACACCCGCCTC
CCCTTATCCCGAAGTCCATCAGCAGCTCACTGAGGATCTGGGGGCTCCCCCCGAGGAAATATTTGCCGCCTTTGAGCCGG
AACCGTTCGCCGCCGGGTCTATTGCCCAGGTCCATCTTGCACGACTGGAAGATGGTACCGAAGTTGTGGTCAAGGTGCGG
CGTCCCGGCATTCGGGTGGTGGTTGAAGCGGATTTGCGCTGGCTCTCTAGACTTGCCGAACTTATCGAAACCGGCAACTC
GGAACTGCGTCATTTTCATTGGCAGGAAGTGGTTGCGCAATTTACACAGTCACTCCGGCGTGAACTCGATTTTGGTGCTG
AATGCCGCCATGCAGAACGTGTTGCCTCTAACTTCGCCGGCTACTCGGACGAGGCCTCGCCCATTTTGCCCCTGGCACAG
CCTGCCGGCGAGGGTGAATCTTCTTCGTTACTTCCACTCATTGTCATTCCCAAGGTTTATTGGCAATGGACCGGTGAACG
CGTATGTGTGCAGGAGTATATTCAAGGTATTTCAGGTCGGGATGTCGCGGCGGTGGATCGGGCGGGTCTTGACCGCAAGG
TTCTCGCCCGCCGTGGGGTGGGGGCGGTGATAAAAATGATACTGGTGGATGGCCTGTTCCACGCAGACCCGCACCCTGGC
AACCTGTTTTATCTTCCGGGCAATCGAATTGCCTTCATCGATTTCGGCATGATCGGCCTGCTGGGGGAAGCACGGCGCGG
AGAGCTGATTCATCTTTTACTCGGGTTGGTTCAGTATGATTCCGCCGCGGTAGCCGGTGTGTTGCTCGACTGGACCGGGG
AGGGGGATGTCAACGAAGAAGCGCTTAAGACTGAAATCCAGCTGTTTGTCGATCAATATCTGGGCGTTCCTCTAAAGCAG
CTCAAGCTTGGTTCCATGCTTGCAGATCTTGTTGCCATCCTGCGCGGACATCGGCTGCATCTGCCGCCCGATCTTGCGCT
CTTTTTCAAGGCGTTCATTACGCTTGAAGGCACAGGAAGAGAGCTCGATCCGGAACTGGATATCGCAGGCGAAGCACTGC
CCCTGTTACGGGATGCAATGGCTATCCGTTACGCGCCAGCCGCCATGGCAAAGCGCGGATGGCGCACAGCGATCGAGCTG
GCAAGCCTGCTAAGCAATCTGCCTCGCGATCTCTCGCGATTGTTGCGTTCCGCCCGTCGGGGCAAAGTGGATATTCATAT
CGAGGTGGCGCATCTCAAACACGTTGGTGATCAACTGGACGGTGCAGTCAACCGGTTGGTCGTGGGTATCGTGGTTGCCG
CTGTCATCGTGGGTTCCTCAGTCGTGATGGCAGTTTCCACCGGGCCCACTCTATGGGGCGTCCCTTTCTTCAGTCTGCTC
GGCTTTGCCTGTGCAACGATTGGGGCAATATGGCTGTTTTCGGCCATTTCCCGCGCCAACAGGGCCGATCGCGAGAGGAA
GCCGCGAGGCGATTGA

Upstream 100 bases:

>100_bases
TCAGGCTGTGGAAGCGTGGCTGTATGACACGGTCCAGAGACTGGAGCGGGATTAGATAAGGTAAAGGTCGGGTCGAAATC
ATGAATCCGGGAAAGAGCTG

Downstream 100 bases:

>100_bases
TCGCAGGCTTGCGCTTGTTTGCGTGTGCTCGTATTCATAGCTCTCTATTTCATTCTTCCTTTCAGTAGCAGAAACCGGGG
TAGAAAATGAGAACAATCGA

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 591; Mature: 591

Protein sequence:

>591_residues
MLWQAMTAARDLGRLHEIASILIRHGFGDVVRRLGFAHALERAGRALRWSEATELAQLEPQASVRRAMEEMGPTFVKLGQ
ILATRVDLFDPEWIAEFSKLQDSTPASPYPEVHQQLTEDLGAPPEEIFAAFEPEPFAAGSIAQVHLARLEDGTEVVVKVR
RPGIRVVVEADLRWLSRLAELIETGNSELRHFHWQEVVAQFTQSLRRELDFGAECRHAERVASNFAGYSDEASPILPLAQ
PAGEGESSSLLPLIVIPKVYWQWTGERVCVQEYIQGISGRDVAAVDRAGLDRKVLARRGVGAVIKMILVDGLFHADPHPG
NLFYLPGNRIAFIDFGMIGLLGEARRGELIHLLLGLVQYDSAAVAGVLLDWTGEGDVNEEALKTEIQLFVDQYLGVPLKQ
LKLGSMLADLVAILRGHRLHLPPDLALFFKAFITLEGTGRELDPELDIAGEALPLLRDAMAIRYAPAAMAKRGWRTAIEL
ASLLSNLPRDLSRLLRSARRGKVDIHIEVAHLKHVGDQLDGAVNRLVVGIVVAAVIVGSSVVMAVSTGPTLWGVPFFSLL
GFACATIGAIWLFSAISRANRADRERKPRGD

Sequences:

>Translated_591_residues
MLWQAMTAARDLGRLHEIASILIRHGFGDVVRRLGFAHALERAGRALRWSEATELAQLEPQASVRRAMEEMGPTFVKLGQ
ILATRVDLFDPEWIAEFSKLQDSTPASPYPEVHQQLTEDLGAPPEEIFAAFEPEPFAAGSIAQVHLARLEDGTEVVVKVR
RPGIRVVVEADLRWLSRLAELIETGNSELRHFHWQEVVAQFTQSLRRELDFGAECRHAERVASNFAGYSDEASPILPLAQ
PAGEGESSSLLPLIVIPKVYWQWTGERVCVQEYIQGISGRDVAAVDRAGLDRKVLARRGVGAVIKMILVDGLFHADPHPG
NLFYLPGNRIAFIDFGMIGLLGEARRGELIHLLLGLVQYDSAAVAGVLLDWTGEGDVNEEALKTEIQLFVDQYLGVPLKQ
LKLGSMLADLVAILRGHRLHLPPDLALFFKAFITLEGTGRELDPELDIAGEALPLLRDAMAIRYAPAAMAKRGWRTAIEL
ASLLSNLPRDLSRLLRSARRGKVDIHIEVAHLKHVGDQLDGAVNRLVVGIVVAAVIVGSSVVMAVSTGPTLWGVPFFSLL
GFACATIGAIWLFSAISRANRADRERKPRGD
>Mature_591_residues
MLWQAMTAARDLGRLHEIASILIRHGFGDVVRRLGFAHALERAGRALRWSEATELAQLEPQASVRRAMEEMGPTFVKLGQ
ILATRVDLFDPEWIAEFSKLQDSTPASPYPEVHQQLTEDLGAPPEEIFAAFEPEPFAAGSIAQVHLARLEDGTEVVVKVR
RPGIRVVVEADLRWLSRLAELIETGNSELRHFHWQEVVAQFTQSLRRELDFGAECRHAERVASNFAGYSDEASPILPLAQ
PAGEGESSSLLPLIVIPKVYWQWTGERVCVQEYIQGISGRDVAAVDRAGLDRKVLARRGVGAVIKMILVDGLFHADPHPG
NLFYLPGNRIAFIDFGMIGLLGEARRGELIHLLLGLVQYDSAAVAGVLLDWTGEGDVNEEALKTEIQLFVDQYLGVPLKQ
LKLGSMLADLVAILRGHRLHLPPDLALFFKAFITLEGTGRELDPELDIAGEALPLLRDAMAIRYAPAAMAKRGWRTAIEL
ASLLSNLPRDLSRLLRSARRGKVDIHIEVAHLKHVGDQLDGAVNRLVVGIVVAAVIVGSSVVMAVSTGPTLWGVPFFSLL
GFACATIGAIWLFSAISRANRADRERKPRGD

Specific function: Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis [H]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC1 family. UbiB subfamily [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=293, Percent_Identity=31.3993174061433, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI40254938, Length=296, Percent_Identity=29.0540540540541, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI217035081, Length=268, Percent_Identity=27.9850746268657, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI34147522, Length=329, Percent_Identity=24.3161094224924, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI2367309, Length=543, Percent_Identity=29.097605893186, Blast_Score=198, Evalue=9e-52,
Organism=Caenorhabditis elegans, GI17559152, Length=271, Percent_Identity=27.3062730627306, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI32565180, Length=268, Percent_Identity=25, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6325148, Length=458, Percent_Identity=23.3624454148472, Blast_Score=115, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6323282, Length=261, Percent_Identity=26.4367816091954, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321319, Length=265, Percent_Identity=24.1509433962264, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI22024280, Length=294, Percent_Identity=29.5918367346939, Blast_Score=138, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24662575, Length=286, Percent_Identity=28.3216783216783, Blast_Score=119, Evalue=7e-27,
Organism=Drosophila melanogaster, GI18859849, Length=268, Percent_Identity=25.3731343283582, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR010232 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 64959; Mature: 64959

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWQAMTAARDLGRLHEIASILIRHGFGDVVRRLGFAHALERAGRALRWSEATELAQLEP
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
QASVRRAMEEMGPTFVKLGQILATRVDLFDPEWIAEFSKLQDSTPASPYPEVHQQLTEDL
HHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
GAPPEEIFAAFEPEPFAAGSIAQVHLARLEDGTEVVVKVRRPGIRVVVEADLRWLSRLAE
CCCHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCEEEEEHHHHHHHHHHHH
LIETGNSELRHFHWQEVVAQFTQSLRRELDFGAECRHAERVASNFAGYSDEASPILPLAQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
PAGEGESSSLLPLIVIPKVYWQWTGERVCVQEYIQGISGRDVAAVDRAGLDRKVLARRGV
CCCCCCCCCCCCEEEECHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHCCH
GAVIKMILVDGLFHADPHPGNLFYLPGNRIAFIDFGMIGLLGEARRGELIHLLLGLVQYD
HHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEECCHHHHHCCCCCCHHHHHHHHHHHHC
SAAVAGVLLDWTGEGDVNEEALKTEIQLFVDQYLGVPLKQLKLGSMLADLVAILRGHRLH
CHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
LPPDLALFFKAFITLEGTGRELDPELDIAGEALPLLRDAMAIRYAPAAMAKRGWRTAIEL
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
ASLLSNLPRDLSRLLRSARRGKVDIHIEVAHLKHVGDQLDGAVNRLVVGIVVAAVIVGSS
HHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VVMAVSTGPTLWGVPFFSLLGFACATIGAIWLFSAISRANRADRERKPRGD
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLWQAMTAARDLGRLHEIASILIRHGFGDVVRRLGFAHALERAGRALRWSEATELAQLEP
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
QASVRRAMEEMGPTFVKLGQILATRVDLFDPEWIAEFSKLQDSTPASPYPEVHQQLTEDL
HHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
GAPPEEIFAAFEPEPFAAGSIAQVHLARLEDGTEVVVKVRRPGIRVVVEADLRWLSRLAE
CCCHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCEEEEEHHHHHHHHHHHH
LIETGNSELRHFHWQEVVAQFTQSLRRELDFGAECRHAERVASNFAGYSDEASPILPLAQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
PAGEGESSSLLPLIVIPKVYWQWTGERVCVQEYIQGISGRDVAAVDRAGLDRKVLARRGV
CCCCCCCCCCCCEEEECHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHCCH
GAVIKMILVDGLFHADPHPGNLFYLPGNRIAFIDFGMIGLLGEARRGELIHLLLGLVQYD
HHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEECCHHHHHCCCCCCHHHHHHHHHHHHC
SAAVAGVLLDWTGEGDVNEEALKTEIQLFVDQYLGVPLKQLKLGSMLADLVAILRGHRLH
CHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
LPPDLALFFKAFITLEGTGRELDPELDIAGEALPLLRDAMAIRYAPAAMAKRGWRTAIEL
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
ASLLSNLPRDLSRLLRSARRGKVDIHIEVAHLKHVGDQLDGAVNRLVVGIVVAAVIVGSS
HHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VVMAVSTGPTLWGVPFFSLLGFACATIGAIWLFSAISRANRADRERKPRGD
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA