| Definition | Shigella boydii Sb227, complete genome. |
|---|---|
| Accession | NC_007613 |
| Length | 4,519,823 |
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The map label for this gene is entA [H]
Identifier: 82543042
GI number: 82543042
Start: 477028
End: 477774
Strand: Direct
Name: entA [H]
Synonym: SBO_0457
Alternate gene names: 82543042
Gene position: 477028-477774 (Clockwise)
Preceding gene: 82543041
Following gene: 82543043
Centisome position: 10.55
GC content: 57.7
Gene sequence:
>747_bases ATGGATTTCAGCGGTAAAAATGTCTGGGTAACCGGCGCAGGTAAAGGTATCGGCTACGCCACGGCGCTGGCGTTTGTTGA GGCGGGAGCGAAAGTTACAGGTTTTGATCAAGCGTTCACTCAGGAGCAATATCCCTTTGCGACCGAAGTAATGGATGTTG CCGACGCCGGGCAGGTGGCGCAGGTATGTCAGCGACTGTTAGCTGAAACGGAGCGACTGGACGTGCTGATCAATGCGGCG GGAATTTTGCGCATGGGCGCGACCGATCAGCTCAGTAAAGAGGACTGGCAGCAGACTTTTGCGGTTAACGTCGGCGGTGC GTTTAACCTGTTCCAGCAAACCATGAACCAGTTTCGCCGTCAGCGGGGCGGGGCGATTGTCACTGTGGCGTCCGACGCCG CACACACGCCGCGTATTGGTATGAGTGCTTATGGCGCATCGAAAGCGGCGCTGAAAAGCCTGGCGTTGAGCGTCGGGCTG GAACTGGCGGGTAGCGGCGTGCGCTGTAATGTGGTTTCGCCTGGCTCCACCGACACCGATATGCAACGCACGCTGTGGGT GAGCGATGACGCCGAAGAACAGCGTATTCGCGGCTTTGGCGAGCAGTTTAAACTCGGCATTCCGCTGGGGAAAATCGCCC GTCCACAAGAGATCGCCAACACGATTTTGTTCCTCGCCTCTGACCTCGCCAGCCATATCACCCTACAGGATATTGTGGTC GATGGCGGCTCAACGCTGGGGGCATAA
Upstream 100 bases:
>100_bases CGCGCTGGCGCAAAGTGCATGGTGATATCGACTTTGTCATGCTGGCGAAAAACCCGACCATCGACGCCTGGTGGAAGCTA CTCTCCCGCGAGGTTAAATA
Downstream 100 bases:
>100_bases GCATGATCTGGAAACGCCATTTAACGCTCGACGAACTGAACGCCACCAGCGATAACACAATGGTGGCGCATCTGGGAATT GTGTATACCCGTCTGGGAGA
Product: 2,3-dihydroxybenzoate-2,3-dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 248; Mature: 248
Protein sequence:
>248_residues MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAGQVAQVCQRLLAETERLDVLINAA GILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVV DGGSTLGA
Sequences:
>Translated_248_residues MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAGQVAQVCQRLLAETERLDVLINAA GILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVV DGGSTLGA >Mature_248_residues MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAGQVAQVCQRLLAETERLDVLINAA GILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVV DGGSTLGA
Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=32.6693227091633, Blast_Score=109, Evalue=3e-24, Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=30.8880308880309, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=29.9595141700405, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=29.4354838709677, Blast_Score=91, Evalue=8e-19, Organism=Homo sapiens, GI40254992, Length=195, Percent_Identity=32.8205128205128, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI15277342, Length=256, Percent_Identity=30.078125, Blast_Score=85, Evalue=5e-17, Organism=Homo sapiens, GI4504505, Length=208, Percent_Identity=28.8461538461538, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI126723750, Length=265, Percent_Identity=26.7924528301887, Blast_Score=81, Evalue=7e-16, Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=24.21875, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=30.6878306878307, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=25, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI31542939, Length=263, Percent_Identity=28.8973384030418, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=25.974025974026, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI4503817, Length=236, Percent_Identity=24.5762711864407, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=98.7903225806452, Blast_Score=499, Evalue=1e-143, Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=35.6, Blast_Score=128, Evalue=5e-31, Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=31.0077519379845, Blast_Score=116, Evalue=2e-27, Organism=Escherichia coli, GI1788459, Length=197, Percent_Identity=31.4720812182741, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=25.6916996047431, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=27.6, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=31.1023622047244, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI1789378, Length=264, Percent_Identity=28.030303030303, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=27.5590551181102, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI87082160, Length=262, Percent_Identity=27.0992366412214, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=29.1497975708502, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1787820, Length=176, Percent_Identity=29.5454545454545, Blast_Score=72, Evalue=5e-14, Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=32.4, Blast_Score=114, Evalue=6e-26, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=34.9624060150376, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=34.3396226415094, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=34.7328244274809, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=34.0996168582375, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=32.824427480916, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=30.1960784313725, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=34.0823970037453, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=34.3283582089552, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=33.0827067669173, Blast_Score=99, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=29.9625468164794, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=31.4393939393939, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=32.1969696969697, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=28.125, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=30.0751879699248, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=31.2, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=29.7959183673469, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=29.9242424242424, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=29.0836653386454, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI71994600, Length=172, Percent_Identity=33.7209302325581, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17508651, Length=194, Percent_Identity=30.9278350515464, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=29.368029739777, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=30, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=28.7313432835821, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=30.6818181818182, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI212645366, Length=250, Percent_Identity=31.6, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17568967, Length=205, Percent_Identity=30.2439024390244, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=29.6153846153846, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17538182, Length=229, Percent_Identity=29.2576419213974, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17508895, Length=194, Percent_Identity=28.8659793814433, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=28.5171102661597, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI193207185, Length=148, Percent_Identity=36.4864864864865, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17564282, Length=190, Percent_Identity=30, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17561272, Length=200, Percent_Identity=24.5, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=29.7709923664122, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=219, Percent_Identity=28.7671232876712, Blast_Score=74, Evalue=3e-14, Organism=Saccharomyces cerevisiae, GI6322227, Length=197, Percent_Identity=28.4263959390863, Blast_Score=73, Evalue=3e-14, Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=28.2722513089005, Blast_Score=72, Evalue=9e-14, Organism=Saccharomyces cerevisiae, GI6324126, Length=256, Percent_Identity=23.4375, Blast_Score=67, Evalue=2e-12, Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=33.203125, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=33.7349397590361, Blast_Score=104, Evalue=5e-23, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=32.9365079365079, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=31.6, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=31.6205533596838, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=32.0158102766798, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=28.2352941176471, Blast_Score=91, Evalue=8e-19, Organism=Drosophila melanogaster, GI24644337, Length=260, Percent_Identity=32.6923076923077, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=32.6315789473684, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI21356301, Length=190, Percent_Identity=29.4736842105263, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI221331218, Length=216, Percent_Identity=27.3148148148148, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24665243, Length=216, Percent_Identity=27.3148148148148, Blast_Score=67, Evalue=7e-12, Organism=Drosophila melanogaster, GI17737361, Length=236, Percent_Identity=28.8135593220339, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24665247, Length=217, Percent_Identity=27.6497695852535, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI221331216, Length=217, Percent_Identity=27.6497695852535, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI45554248, Length=207, Percent_Identity=28.5024154589372, Blast_Score=64, Evalue=1e-10, Organism=Drosophila melanogaster, GI24640117, Length=207, Percent_Identity=28.5024154589372, Blast_Score=64, Evalue=1e-10,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR003560 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.28 [H]
Molecular weight: Translated: 26278; Mature: 26278
Theoretical pI: Translated: 4.74; Mature: 4.74
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAGQVA CCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEECCHHHHCCCCCCHHHHHHHHHCCCHHH QVCQRLLAETERLDVLINAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRR HHHHHHHHHHHHHHEEEECCHHEEECCCCCCCHHHHHHHEEEECCCHHHHHHHHHHHHHH QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTD HHCCEEEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC MQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVV CHHEEEECCCHHHHHHHCCCCCEEECCCHHCCCCHHHHHHHHHHHHHHHHHHCCHHHEEE DGGSTLGA ECCCCCCC >Mature Secondary Structure MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAGQVA CCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEECCHHHHCCCCCCHHHHHHHHHCCCHHH QVCQRLLAETERLDVLINAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRR HHHHHHHHHHHHHHEEEECCHHEEECCCCCCCHHHHHHHEEEECCCHHHHHHHHHHHHHH QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTD HHCCEEEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC MQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVV CHHEEEECCCHHHHHHHCCCCCEEECCCHHCCCCHHHHHHHHHHHHHHHHHHCCHHHEEE DGGSTLGA ECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2521622; 2521621; 9278503 [H]