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The map label for this gene is engD [H]

Identifier: 78779617

GI number: 78779617

Start: 1147114

End: 1148205

Strand: Reverse

Name: engD [H]

Synonym: PMT9312_1234

Alternate gene names: 78779617

Gene position: 1148205-1147114 (Counterclockwise)

Preceding gene: 78779622

Following gene: 78779616

Centisome position: 67.18

GC content: 32.23

Gene sequence:

>1092_bases
ATGTTAAAAGCAGGTATTATTGGATTACCAAATGTTGGAAAATCAACTTTATTTAATGCACTTGTAGAAAATGCTAAAGC
ACAAGCGGCTAATTTCCCCTTTTGTACTATAGAACCTAATAAAGGTATAGTTTCAGTCCCAGATCAAAGGTTGCAAGAGT
TAGGTGATTTAAGTTCTAGCCAAAATATTATCCCAACAAAAATTGAATTTGTAGATATCGCAGGACTAGTAAAAGGAGCC
AGTAAAGGCGAAGGTTTGGGAAATAAATTTTTATCAAATATTAGGGAGGTTGATGCAATAATTCATGTTGTAAGGTGCTT
TGAGGATAATGATGTAATTCATGTATCCGGGAAGGTAGATCCCTTGGATGACATTGAGATAATTAATCTGGAATTGAATT
TAGCTGATTTATCCCAACTCCAAAAAAGAAGAGAAAGAATTAAAAAACAGGTTAGAACTAGTAAAGAGGCAGCAAAAGAA
GATGCTTTACTAGAAAAAATTGAAGAAGAGTTACATAAAGGACTTTCAGTTAGATCAATATCTTTGAGTGAAGAAGAAAA
TTTAATAATTAAGCAATTAGGCTTTCTTACCGCAAAACCAATTATTTACGCAACAAATTTGAATGAAAATGATTTAGCTG
AAGGTAATGATTTCTCATCAAAAGTTCAGAGTTTTGCAGGTAGTGAAAATACAGAATGCATAAAAATATCAGCTCAAGTG
GAATCTGAATTAATAGAGTTAGAACCAGAAGATAAAAAAGACTACCTTATTGGTTTAGGAGTAGAAGAAGGGGGATTAAG
TTCTTTAATTAGATCAACATATAAATTACTGGGATTAAAAACTTATTTCACTACTGGAGAAAAGGAGACAAAAGCCTGGA
CTATAAAAGATGGGATGACTGCGCCACAAGCAGCAGGCGTCATCCATACTGATTTTGAAAAAGGATTTATTAGAGCTCAA
ACTATTTCATATCAAAATTTAATTGATTCTGGTTCAATTGCAAATGCAAAAACTAAAGGTTTGTTAAGAAGTGAAGGTAA
GGAATATATTGTAAACGAAGGAGATGTAATGGAGTTCTTATTTAATGTTTAG

Upstream 100 bases:

>100_bases
ATAATCAAGACGATTATAATTAACTTATCCAAGATTGGTTAAGTAAATACTATATTACTAGAAGATGTTTTCTTGATAAT
TTTTCCATAAATTTTTTCAA

Downstream 100 bases:

>100_bases
TAAGTCTCTTAAGGCTTACTATTTTGCTTTTTGAATTTAAATTCAAAAAATGAAATTAATAAAATTAAGATACATCCTAA
GCAACTTCCTACTAACCCAA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDQRLQELGDLSSSQNIIPTKIEFVDIAGLVKGA
SKGEGLGNKFLSNIREVDAIIHVVRCFEDNDVIHVSGKVDPLDDIEIINLELNLADLSQLQKRRERIKKQVRTSKEAAKE
DALLEKIEEELHKGLSVRSISLSEEENLIIKQLGFLTAKPIIYATNLNENDLAEGNDFSSKVQSFAGSENTECIKISAQV
ESELIELEPEDKKDYLIGLGVEEGGLSSLIRSTYKLLGLKTYFTTGEKETKAWTIKDGMTAPQAAGVIHTDFEKGFIRAQ
TISYQNLIDSGSIANAKTKGLLRSEGKEYIVNEGDVMEFLFNV

Sequences:

>Translated_363_residues
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDQRLQELGDLSSSQNIIPTKIEFVDIAGLVKGA
SKGEGLGNKFLSNIREVDAIIHVVRCFEDNDVIHVSGKVDPLDDIEIINLELNLADLSQLQKRRERIKKQVRTSKEAAKE
DALLEKIEEELHKGLSVRSISLSEEENLIIKQLGFLTAKPIIYATNLNENDLAEGNDFSSKVQSFAGSENTECIKISAQV
ESELIELEPEDKKDYLIGLGVEEGGLSSLIRSTYKLLGLKTYFTTGEKETKAWTIKDGMTAPQAAGVIHTDFEKGFIRAQ
TISYQNLIDSGSIANAKTKGLLRSEGKEYIVNEGDVMEFLFNV
>Mature_363_residues
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDQRLQELGDLSSSQNIIPTKIEFVDIAGLVKGA
SKGEGLGNKFLSNIREVDAIIHVVRCFEDNDVIHVSGKVDPLDDIEIINLELNLADLSQLQKRRERIKKQVRTSKEAAKE
DALLEKIEEELHKGLSVRSISLSEEENLIIKQLGFLTAKPIIYATNLNENDLAEGNDFSSKVQSFAGSENTECIKISAQV
ESELIELEPEDKKDYLIGLGVEEGGLSSLIRSTYKLLGLKTYFTTGEKETKAWTIKDGMTAPQAAGVIHTDFEKGFIRAQ
TISYQNLIDSGSIANAKTKGLLRSEGKEYIVNEGDVMEFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=40.650406504065, Blast_Score=269, Evalue=2e-72,
Organism=Homo sapiens, GI58761502, Length=171, Percent_Identity=38.5964912280702, Blast_Score=126, Evalue=4e-29,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=55.0964187327824, Blast_Score=401, Evalue=1e-113,
Organism=Escherichia coli, GI1789574, Length=128, Percent_Identity=31.25, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=42.6229508196721, Blast_Score=281, Evalue=5e-76,
Organism=Saccharomyces cerevisiae, GI6319499, Length=368, Percent_Identity=40.2173913043478, Blast_Score=247, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6321773, Length=378, Percent_Identity=35.1851851851852, Blast_Score=216, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6321649, Length=168, Percent_Identity=39.2857142857143, Blast_Score=93, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24640873, Length=376, Percent_Identity=40.4255319148936, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24640877, Length=376, Percent_Identity=40.4255319148936, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24640875, Length=376, Percent_Identity=40.4255319148936, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24640879, Length=334, Percent_Identity=37.7245508982036, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24585318, Length=141, Percent_Identity=36.1702127659575, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39874; Mature: 39874

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDQRLQELGDLSSS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCHHHHHHHHCCCCC
QNIIPTKIEFVDIAGLVKGASKGEGLGNKFLSNIREVDAIIHVVRCFEDNDVIHVSGKVD
CCCCCCEEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PLDDIEIINLELNLADLSQLQKRRERIKKQVRTSKEAAKEDALLEKIEEELHKGLSVRSI
CCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
SLSEEENLIIKQLGFLTAKPIIYATNLNENDLAEGNDFSSKVQSFAGSENTECIKISAQV
ECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEHH
ESELIELEPEDKKDYLIGLGVEEGGLSSLIRSTYKLLGLKTYFTTGEKETKAWTIKDGMT
HHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCC
APQAAGVIHTDFEKGFIRAQTISYQNLIDSGSIANAKTKGLLRSEGKEYIVNEGDVMEFL
CCCCCCCEEECCCCCEEEEEEECHHHHHCCCCCCCHHHHHHHHHCCCEEECCCCHHHHHH
FNV
HCC
>Mature Secondary Structure
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDQRLQELGDLSSS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCHHHHHHHHCCCCC
QNIIPTKIEFVDIAGLVKGASKGEGLGNKFLSNIREVDAIIHVVRCFEDNDVIHVSGKVD
CCCCCCEEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PLDDIEIINLELNLADLSQLQKRRERIKKQVRTSKEAAKEDALLEKIEEELHKGLSVRSI
CCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
SLSEEENLIIKQLGFLTAKPIIYATNLNENDLAEGNDFSSKVQSFAGSENTECIKISAQV
ECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEHH
ESELIELEPEDKKDYLIGLGVEEGGLSSLIRSTYKLLGLKTYFTTGEKETKAWTIKDGMT
HHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCC
APQAAGVIHTDFEKGFIRAQTISYQNLIDSGSIANAKTKGLLRSEGKEYIVNEGDVMEFL
CCCCCCCEEECCCCCEEEEEEECHHHHHCCCCCCCHHHHHHHHHCCCEEECCCCHHHHHH
FNV
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]