Click here to switch to the map view.

The map label for this gene is trpD

Identifier: 78779231

GI number: 78779231

Start: 783257

End: 784306

Strand: Direct

Name: trpD

Synonym: PMT9312_0847

Alternate gene names: 78779231

Gene position: 783257-784306 (Clockwise)

Preceding gene: 78779230

Following gene: 78779232

Centisome position: 45.83

GC content: 34.48

Gene sequence:

>1050_bases
ATGTCTTTTAACATTTCTAACGCTGAAATCTTAAATATTTTGTTGGAGGGAGGAAATCTTGATGAGTTAACTTCTAGTTT
GTTAATGCAAAGATGGCTTAATGATGAAATATCTGATGTTCAAACAGGAGCTTTTTTGAGCGCTTTGAGAGCTAAGGGCT
GCACAGGTGTTGAATTGTCTTCTATGGCCGAGGAACTCTTGAAAGTTTGCGAGTTGCCAGTAGCAAGACCAAATTTGTAT
ATGGTAGATACTTGTGGAACTGGAGGTGATGGAGCTAATACATTTAATATTTCCACTGCGGTAGCATTTGTGGCTGCATC
TTGTGGTGCAAAAATTGCTAAACATGGAAATAAAAGTGCAAGTGGAAAGGTTGGCTCTGCTGATGTTTTGTTGAATCTTG
GCTTAAATTTAAATTGTTCATTAAAAAAAGTAATCTCAGCCGTTAATGAAATTGGAATAACTTTTTTGTTTGCACCTGTT
TGGCATAAATCTTTAATTAAACTTGCTCCTTTAAGAAAAGCCCTTGGAATAAGGACTGTATTTAATCAACTTGGACCATT
GGTAAATCCTTTAAGACCTAATGCGCAAGTATTAGGTGTTGCTTCTGAAGATCTTTTAGAGCCTATGGGAAGTGCGCTAT
TGAAAATGGGAATGAATAGAGTGATAGTAGTTCATGGCTCTGGCGGCCTTGATGAAGCATCACTTCAAGGAGACAATAAA
TTAGTATTTGTAGAGAAAGGAAAATTACGATTTTCAAAAATAAATATCTTAGATTTTAATCATGAAAATATTCCAAACGA
CAAGCTTGTTGTTTCTGGCAGTGACTCTAATGAGGAAATATTAAAGTCTGTTTTAAATGGTTCTGGACAAAAATCGCATA
AAGATGTTGTTGCCTTGAATGCTGCATTAGTTTTATGGGCAGCAGGAATTGAGGATGATTTACATAAAGGTTTTAATAAA
GCTTTATTTTCAATTAATCAAGGAAATCCTTGGGAGAAATTTTTACTCTTAAAAACTTATTTATCCTCAGATGATTTAAT
TTCACCTTAA

Upstream 100 bases:

>100_bases
CAAAAAGCTTCAGGCCTTCTAATACAAATAAAGAATTAGTTGGGTCAGGTTTTGATACTTCAAATTGAATTTCATTTTCA
CATTTTTCTTTAATAAATAA

Downstream 100 bases:

>100_bases
TGATTAATTCCTATAAGAAAAATGCAAAATTAGTTTTAAGTAATGGATTGATATTTCCTGGATTTTCTTTTGGATATTCG
GGAACTGCTGTTGGCGAAAT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSFNISNAEILNILLEGGNLDELTSSLLMQRWLNDEISDVQTGAFLSALRAKGCTGVELSSMAEELLKVCELPVARPNLY
MVDTCGTGGDGANTFNISTAVAFVAASCGAKIAKHGNKSASGKVGSADVLLNLGLNLNCSLKKVISAVNEIGITFLFAPV
WHKSLIKLAPLRKALGIRTVFNQLGPLVNPLRPNAQVLGVASEDLLEPMGSALLKMGMNRVIVVHGSGGLDEASLQGDNK
LVFVEKGKLRFSKINILDFNHENIPNDKLVVSGSDSNEEILKSVLNGSGQKSHKDVVALNAALVLWAAGIEDDLHKGFNK
ALFSINQGNPWEKFLLLKTYLSSDDLISP

Sequences:

>Translated_349_residues
MSFNISNAEILNILLEGGNLDELTSSLLMQRWLNDEISDVQTGAFLSALRAKGCTGVELSSMAEELLKVCELPVARPNLY
MVDTCGTGGDGANTFNISTAVAFVAASCGAKIAKHGNKSASGKVGSADVLLNLGLNLNCSLKKVISAVNEIGITFLFAPV
WHKSLIKLAPLRKALGIRTVFNQLGPLVNPLRPNAQVLGVASEDLLEPMGSALLKMGMNRVIVVHGSGGLDEASLQGDNK
LVFVEKGKLRFSKINILDFNHENIPNDKLVVSGSDSNEEILKSVLNGSGQKSHKDVVALNAALVLWAAGIEDDLHKGFNK
ALFSINQGNPWEKFLLLKTYLSSDDLISP
>Mature_348_residues
SFNISNAEILNILLEGGNLDELTSSLLMQRWLNDEISDVQTGAFLSALRAKGCTGVELSSMAEELLKVCELPVARPNLYM
VDTCGTGGDGANTFNISTAVAFVAASCGAKIAKHGNKSASGKVGSADVLLNLGLNLNCSLKKVISAVNEIGITFLFAPVW
HKSLIKLAPLRKALGIRTVFNQLGPLVNPLRPNAQVLGVASEDLLEPMGSALLKMGMNRVIVVHGSGGLDEASLQGDNKL
VFVEKGKLRFSKINILDFNHENIPNDKLVVSGSDSNEEILKSVLNGSGQKSHKDVVALNAALVLWAAGIEDDLHKGFNKA
LFSINQGNPWEKFLLLKTYLSSDDLISP

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=328, Percent_Identity=35.9756097560976, Blast_Score=183, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320561, Length=322, Percent_Identity=31.3664596273292, Blast_Score=111, Evalue=2e-25,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_PROM9 (Q31B38)

Other databases:

- EMBL:   CP000111
- RefSeq:   YP_397343.1
- HSSP:   P66992
- ProteinModelPortal:   Q31B38
- SMR:   Q31B38
- STRING:   Q31B38
- GeneID:   3765648
- GenomeReviews:   CP000111_GR
- KEGG:   pmi:PMT9312_0847
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   HGNKSAS
- ProtClustDB:   PRK00188
- BioCyc:   PMAR74546:PMT9312_0847-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 37277; Mature: 37146

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNISNAEILNILLEGGNLDELTSSLLMQRWLNDEISDVQTGAFLSALRAKGCTGVELS
CCCCCCCHHEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHH
SMAEELLKVCELPVARPNLYMVDTCGTGGDGANTFNISTAVAFVAASCGAKIAKHGNKSA
HHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCC
SGKVGSADVLLNLGLNLNCSLKKVISAVNEIGITFLFAPVWHKSLIKLAPLRKALGIRTV
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCHHEEEHHHHHHHHHHHHHHHHHHHHHHH
FNQLGPLVNPLRPNAQVLGVASEDLLEPMGSALLKMGMNRVIVVHGSGGLDEASLQGDNK
HHHHCHHCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCE
LVFVEKGKLRFSKINILDFNHENIPNDKLVVSGSDSNEEILKSVLNGSGQKSHKDVVALN
EEEEECCCEEEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHH
AALVLWAAGIEDDLHKGFNKALFSINQGNPWEKFLLLKTYLSSDDLISP
HHHHHHCCCCHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SFNISNAEILNILLEGGNLDELTSSLLMQRWLNDEISDVQTGAFLSALRAKGCTGVELS
CCCCCCHHEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHH
SMAEELLKVCELPVARPNLYMVDTCGTGGDGANTFNISTAVAFVAASCGAKIAKHGNKSA
HHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCC
SGKVGSADVLLNLGLNLNCSLKKVISAVNEIGITFLFAPVWHKSLIKLAPLRKALGIRTV
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCHHEEEHHHHHHHHHHHHHHHHHHHHHHH
FNQLGPLVNPLRPNAQVLGVASEDLLEPMGSALLKMGMNRVIVVHGSGGLDEASLQGDNK
HHHHCHHCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCE
LVFVEKGKLRFSKINILDFNHENIPNDKLVVSGSDSNEEILKSVLNGSGQKSHKDVVALN
EEEEECCCEEEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHH
AALVLWAAGIEDDLHKGFNKALFSINQGNPWEKFLLLKTYLSSDDLISP
HHHHHHCCCCHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA