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The map label for this gene is pqqL [C]

Identifier: 78779138

GI number: 78779138

Start: 699415

End: 700680

Strand: Reverse

Name: pqqL [C]

Synonym: PMT9312_0754

Alternate gene names: 78779138

Gene position: 700680-699415 (Counterclockwise)

Preceding gene: 78779150

Following gene: 78779137

Centisome position: 40.99

GC content: 30.41

Gene sequence:

>1266_bases
ATGAATGTAGGAGAGGTTAACTACTATACCCATTCAAGCAAAACTAGATGTGTATTTGTGGATAATAAAGAATTACCGCT
TGTAAGCATTGATATTTGGTGCAAAGCAGGTTCTTCATTTGAGGAAGTTGATAAAAATGGCACTGCTCATTTTCTAGAGC
ATATGATTTTTAAAGGATCTAACAACATAATGCCAGGTGAATTTGATCATAAAATTGAATCACTTGGCGGATTAAGCAAT
GCCTCAACAGGTTATGATGATGTACATTACCATGTCCTCATTCCACCAAATAACTTTAGAGAATCACTTGCTCTTTTGAC
AAATATTGTCGTTTCTCCAAATTTTAATCCTGATGAGTTTATAAAAGAAAAAGGGGTGGTCATTGATGAAATCAAACAAC
AGAATGATCAGCCCGAAGAAAAATTATTTAATTACTTTTTGAAAAGGGTTTGGATAAGTTCTGATTATGCCAATTCTATT
CTCGGAACTGAAAATAGTATTAGAAAATTGGAGATAAATGACCTTGAAAAATTTCATAGAAAACATTATACATCCGAAAA
AATTTGCATGGCAATTGCCGGGAATCTCTCTGGAGAAATATATAAAATTTTTGAAAACAGTGATCTATCTGGGATAAAGA
AAAATCCAAAGAATAAAGATCCAAATTTACTAAATCTTGAAAATAAACCTTTTTTAAAAATTAGGAATGGTAGAGAGTTA
ATTAATTTTGATAATTTAGAGTTTTCAAGAATATTTATGGCATGGTTTATCCCAAACCTCAATGATCAAAAAACGATTAT
TGGATTAGAGATATTAGCATCAGTACTCTCTGTAGGAAGAAACAGCAGGTTAGTAAAATTTTTAAAAGAGGACAATAATC
TTGTTGAATCAGTATATGTAGATGTAAATGCTGGTGAATTAGGTGGATTATTTATCTTGGAAGCAACTTGTGAACCCAAA
GATATTTATTTAGTAGAAAACGAGATTCTTAAAATAATAGATGAAATCTCAGATTCTAAAGCTTTGACTTTGGATGAAAT
AAAAAAAGCCATAAATATAGTCAAAAGCAATTATGTTTTTAATCTAGAGACATCTTCACAGCTTTCTGCATTCTTTGGGA
ATGAACTTCTTTGGGGGAGAAAATCTTCGATCAATAATTTAAAAGGTCATTTAAAGTATTGGAAGGATTTGGGGAATTTT
AAAGAGATCATAAATTATATTCATGGAGATAAATTCACCTTAATAGTATCCCCTAGTAAATGTTAA

Upstream 100 bases:

>100_bases
AACAATTCCAAAATTAGAGGGTCTGTTAATTTAGTTTTAGTTAAAGATTCAGACAACAAGAGTAAAAAGTACCAAAATAG
AGTTTAAAGAGAGAATTTAA

Downstream 100 bases:

>100_bases
AAAGATATTTTTTAAATCATAAACAAAGAAATTTTTCTACTGCTTCAATTTGGATTAAAGGGGGTAGTGATATGGATAGT
GTTAGCAAAAAAGGTATTAA

Product: Zn-dependent peptidase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MNVGEVNYYTHSSKTRCVFVDNKELPLVSIDIWCKAGSSFEEVDKNGTAHFLEHMIFKGSNNIMPGEFDHKIESLGGLSN
ASTGYDDVHYHVLIPPNNFRESLALLTNIVVSPNFNPDEFIKEKGVVIDEIKQQNDQPEEKLFNYFLKRVWISSDYANSI
LGTENSIRKLEINDLEKFHRKHYTSEKICMAIAGNLSGEIYKIFENSDLSGIKKNPKNKDPNLLNLENKPFLKIRNGREL
INFDNLEFSRIFMAWFIPNLNDQKTIIGLEILASVLSVGRNSRLVKFLKEDNNLVESVYVDVNAGELGGLFILEATCEPK
DIYLVENEILKIIDEISDSKALTLDEIKKAINIVKSNYVFNLETSSQLSAFFGNELLWGRKSSINNLKGHLKYWKDLGNF
KEIINYIHGDKFTLIVSPSKC

Sequences:

>Translated_421_residues
MNVGEVNYYTHSSKTRCVFVDNKELPLVSIDIWCKAGSSFEEVDKNGTAHFLEHMIFKGSNNIMPGEFDHKIESLGGLSN
ASTGYDDVHYHVLIPPNNFRESLALLTNIVVSPNFNPDEFIKEKGVVIDEIKQQNDQPEEKLFNYFLKRVWISSDYANSI
LGTENSIRKLEINDLEKFHRKHYTSEKICMAIAGNLSGEIYKIFENSDLSGIKKNPKNKDPNLLNLENKPFLKIRNGREL
INFDNLEFSRIFMAWFIPNLNDQKTIIGLEILASVLSVGRNSRLVKFLKEDNNLVESVYVDVNAGELGGLFILEATCEPK
DIYLVENEILKIIDEISDSKALTLDEIKKAINIVKSNYVFNLETSSQLSAFFGNELLWGRKSSINNLKGHLKYWKDLGNF
KEIINYIHGDKFTLIVSPSKC
>Mature_421_residues
MNVGEVNYYTHSSKTRCVFVDNKELPLVSIDIWCKAGSSFEEVDKNGTAHFLEHMIFKGSNNIMPGEFDHKIESLGGLSN
ASTGYDDVHYHVLIPPNNFRESLALLTNIVVSPNFNPDEFIKEKGVVIDEIKQQNDQPEEKLFNYFLKRVWISSDYANSI
LGTENSIRKLEINDLEKFHRKHYTSEKICMAIAGNLSGEIYKIFENSDLSGIKKNPKNKDPNLLNLENKPFLKIRNGREL
INFDNLEFSRIFMAWFIPNLNDQKTIIGLEILASVLSVGRNSRLVKFLKEDNNLVESVYVDVNAGELGGLFILEATCEPK
DIYLVENEILKIIDEISDSKALTLDEIKKAINIVKSNYVFNLETSSQLSAFFGNELLWGRKSSINNLKGHLKYWKDLGNF
KEIINYIHGDKFTLIVSPSKC

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=406, Percent_Identity=23.1527093596059, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI46593007, Length=374, Percent_Identity=21.6577540106952, Blast_Score=99, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71999683, Length=179, Percent_Identity=27.9329608938547, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17553678, Length=408, Percent_Identity=22.7941176470588, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323192, Length=365, Percent_Identity=23.8356164383562, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357875, Length=395, Percent_Identity=21.0126582278481, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24646943, Length=395, Percent_Identity=21.0126582278481, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24641429, Length=420, Percent_Identity=21.6666666666667, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 48019; Mature: 48019

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVGEVNYYTHSSKTRCVFVDNKELPLVSIDIWCKAGSSFEEVDKNGTAHFLEHMIFKGS
CCCCCEEEEECCCCEEEEEECCCCCCEEEEEEEECCCCCHHHHHCCCHHHHHHHHHHCCC
NNIMPGEFDHKIESLGGLSNASTGYDDVHYHVLIPPNNFRESLALLTNIVVSPNFNPDEF
CCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHEECCCCCHHHH
IKEKGVVIDEIKQQNDQPEEKLFNYFLKRVWISSDYANSILGTENSIRKLEINDLEKFHR
HHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEHHHHHHHHH
KHYTSEKICMAIAGNLSGEIYKIFENSDLSGIKKNPKNKDPNLLNLENKPFLKIRNGREL
HHCCCHHEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCEE
INFDNLEFSRIFMAWFIPNLNDQKTIIGLEILASVLSVGRNSRLVKFLKEDNNLVESVYV
EECCCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEE
DVNAGELGGLFILEATCEPKDIYLVENEILKIIDEISDSKALTLDEIKKAINIVKSNYVF
EECCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCEEE
NLETSSQLSAFFGNELLWGRKSSINNLKGHLKYWKDLGNFKEIINYIHGDKFTLIVSPSK
EECCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCC
C
C
>Mature Secondary Structure
MNVGEVNYYTHSSKTRCVFVDNKELPLVSIDIWCKAGSSFEEVDKNGTAHFLEHMIFKGS
CCCCCEEEEECCCCEEEEEECCCCCCEEEEEEEECCCCCHHHHHCCCHHHHHHHHHHCCC
NNIMPGEFDHKIESLGGLSNASTGYDDVHYHVLIPPNNFRESLALLTNIVVSPNFNPDEF
CCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHEECCCCCHHHH
IKEKGVVIDEIKQQNDQPEEKLFNYFLKRVWISSDYANSILGTENSIRKLEINDLEKFHR
HHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEHHHHHHHHH
KHYTSEKICMAIAGNLSGEIYKIFENSDLSGIKKNPKNKDPNLLNLENKPFLKIRNGREL
HHCCCHHEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCEE
INFDNLEFSRIFMAWFIPNLNDQKTIIGLEILASVLSVGRNSRLVKFLKEDNNLVESVYV
EECCCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEE
DVNAGELGGLFILEATCEPKDIYLVENEILKIIDEISDSKALTLDEIKKAINIVKSNYVF
EECCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCEEE
NLETSSQLSAFFGNELLWGRKSSINNLKGHLKYWKDLGNFKEIINYIHGDKFTLIVSPSK
EECCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCC
C
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]