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The map label for this gene is gap3 [H]

Identifier: 78779109

GI number: 78779109

Start: 676240

End: 677295

Strand: Reverse

Name: gap3 [H]

Synonym: PMT9312_0725

Alternate gene names: 78779109

Gene position: 677295-676240 (Counterclockwise)

Preceding gene: 78779114

Following gene: 78779108

Centisome position: 39.63

GC content: 33.24

Gene sequence:

>1056_bases
ATGTATGATTTATATAGAAAAAATTTCAAAGTTATGAAAATTGGAATTAATGGTTTTGGAAGAATTGGCAGATTAGTTTT
CAGAGCATTATGGGATAGAGCTGATATAGAAATAACTCACATTAATGAGATAGCAGGAGATTCGAATGCCGCTGCGCATC
TACTCGAATTCGATTCAGTCCATGGCAGATGGGAGAAAGATATAAAGGTTAAAGAAGAAGGAATAATAATTGATGGAATG
AAATTAACCTACACATCTTTTAAAAATTACCTTGATGTTCCTTGGGAAAAATCTTCTGTAGATATTATTTTGGAATGTAC
AGGTAAGAATAAAAAGCCAGACAAACTAAATCCCTATTTTGATTCTCTAGGTATGAAAAGAGTAATAGTAGCTTGTCCAG
TAAAGGGAATTGTAACTGGAGAGGAAGCACTTAATATTGTTTACGGTATAAATCAAAGTCTTTATGACCCTTCCAAACAT
AAATTAGTAACAGCAGCATCCTGCACTACAAATTGTTTAGCTCCGATAGTAAAGGTAATTAATGAAAATTTCTCAATTAA
ACATGGCGCTATTACAACTATTCACGATGTCACGAACACTCAAGTTCCTGTAGATTTTTATAAAAGTGATTTGAGGAGAG
CAAGAGGATGTATGCAAAGTTTAATACCTACTACCACTGGATCTGCTAAAGCTATCGCTGAGATCTTCCCAGAATTAAAA
GGAAAATTAAATGGACATGCAGTAAGAGTTCCTCTGCTTAATGGTTCTTTAACAGATGCAGTTTTTGAATTAAATAAAGA
AGTGACAACTGAACAAGTAAATATGGCACTAAAGGAAGCTTCAGAAACTTATTTAAAAGGAATTCTTGGCTACGAAGAAA
GACCTTTAGTTTCTGCAGATTATGTAAATGACTCCAGAAGTTCAATAGTTGATAGTTTATCAACGATGGTTGTTAATTCA
AATTTATTAAAGATATACGCTTGGTATGACAACGAGTGGGGTTACAGCTGCAGACTTGCAGATCTTACTGAATATGTAAT
CAAAAAAGAGATTTAA

Upstream 100 bases:

>100_bases
ATATCTTTTAACAATTTTAAAGTAATTAAATTTTCCTAAATATAGCTTAAATAAAAAAGATTTCATTAGTCAAAACATCT
TGATACATCAAAATATTTTG

Downstream 100 bases:

>100_bases
TTTATGTCTTTATGAAATTATCTAATATTCAACAATATAGTGTTGTAACAGCAAACTATTGGGCGTTCACGCTTACTGAC
GGCGCATTAAGATTATTAGT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MYDLYRKNFKVMKIGINGFGRIGRLVFRALWDRADIEITHINEIAGDSNAAAHLLEFDSVHGRWEKDIKVKEEGIIIDGM
KLTYTSFKNYLDVPWEKSSVDIILECTGKNKKPDKLNPYFDSLGMKRVIVACPVKGIVTGEEALNIVYGINQSLYDPSKH
KLVTAASCTTNCLAPIVKVINENFSIKHGAITTIHDVTNTQVPVDFYKSDLRRARGCMQSLIPTTTGSAKAIAEIFPELK
GKLNGHAVRVPLLNGSLTDAVFELNKEVTTEQVNMALKEASETYLKGILGYEERPLVSADYVNDSRSSIVDSLSTMVVNS
NLLKIYAWYDNEWGYSCRLADLTEYVIKKEI

Sequences:

>Translated_351_residues
MYDLYRKNFKVMKIGINGFGRIGRLVFRALWDRADIEITHINEIAGDSNAAAHLLEFDSVHGRWEKDIKVKEEGIIIDGM
KLTYTSFKNYLDVPWEKSSVDIILECTGKNKKPDKLNPYFDSLGMKRVIVACPVKGIVTGEEALNIVYGINQSLYDPSKH
KLVTAASCTTNCLAPIVKVINENFSIKHGAITTIHDVTNTQVPVDFYKSDLRRARGCMQSLIPTTTGSAKAIAEIFPELK
GKLNGHAVRVPLLNGSLTDAVFELNKEVTTEQVNMALKEASETYLKGILGYEERPLVSADYVNDSRSSIVDSLSTMVVNS
NLLKIYAWYDNEWGYSCRLADLTEYVIKKEI
>Mature_351_residues
MYDLYRKNFKVMKIGINGFGRIGRLVFRALWDRADIEITHINEIAGDSNAAAHLLEFDSVHGRWEKDIKVKEEGIIIDGM
KLTYTSFKNYLDVPWEKSSVDIILECTGKNKKPDKLNPYFDSLGMKRVIVACPVKGIVTGEEALNIVYGINQSLYDPSKH
KLVTAASCTTNCLAPIVKVINENFSIKHGAITTIHDVTNTQVPVDFYKSDLRRARGCMQSLIPTTTGSAKAIAEIFPELK
GKLNGHAVRVPLLNGSLTDAVFELNKEVTTEQVNMALKEASETYLKGILGYEERPLVSADYVNDSRSSIVDSLSTMVVNS
NLLKIYAWYDNEWGYSCRLADLTEYVIKKEI

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=340, Percent_Identity=39.1176470588235, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI7657116, Length=340, Percent_Identity=35.8823529411765, Blast_Score=240, Evalue=2e-63,
Organism=Escherichia coli, GI1788079, Length=338, Percent_Identity=40.8284023668639, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI1789295, Length=337, Percent_Identity=36.2017804154303, Blast_Score=237, Evalue=8e-64,
Organism=Caenorhabditis elegans, GI32566163, Length=342, Percent_Identity=37.1345029239766, Blast_Score=241, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI17568413, Length=342, Percent_Identity=37.1345029239766, Blast_Score=241, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI17534677, Length=342, Percent_Identity=38.0116959064327, Blast_Score=240, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI17534679, Length=342, Percent_Identity=37.719298245614, Blast_Score=239, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6322409, Length=339, Percent_Identity=40.7079646017699, Blast_Score=275, Evalue=6e-75,
Organism=Saccharomyces cerevisiae, GI6321631, Length=339, Percent_Identity=40.4129793510324, Blast_Score=270, Evalue=3e-73,
Organism=Saccharomyces cerevisiae, GI6322468, Length=339, Percent_Identity=39.5280235988201, Blast_Score=266, Evalue=3e-72,
Organism=Drosophila melanogaster, GI85725000, Length=339, Percent_Identity=40.117994100295, Blast_Score=254, Evalue=4e-68,
Organism=Drosophila melanogaster, GI22023983, Length=339, Percent_Identity=40.117994100295, Blast_Score=254, Evalue=4e-68,
Organism=Drosophila melanogaster, GI17933600, Length=339, Percent_Identity=39.8230088495575, Blast_Score=254, Evalue=7e-68,
Organism=Drosophila melanogaster, GI18110149, Length=339, Percent_Identity=39.8230088495575, Blast_Score=254, Evalue=7e-68,
Organism=Drosophila melanogaster, GI19922412, Length=333, Percent_Identity=38.1381381381381, Blast_Score=243, Evalue=1e-64,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 39328; Mature: 39328

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDLYRKNFKVMKIGINGFGRIGRLVFRALWDRADIEITHINEIAGDSNAAAHLLEFDSV
CCCCHHCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCHHHHHHHHHCC
HGRWEKDIKVKEEGIIIDGMKLTYTSFKNYLDVPWEKSSVDIILECTGKNKKPDKLNPYF
CCCCCCCCEEECCCEEEECCEEEHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCHH
DSLGMKRVIVACPVKGIVTGEEALNIVYGINQSLYDPSKHKLVTAASCTTNCLAPIVKVI
HHCCCCEEEEECCCCCEEECHHHEEEEEECCCHHCCCCCCCEEEECCHHHHHHHHHHHHH
NENFSIKHGAITTIHDVTNTQVPVDFYKSDLRRARGCMQSLIPTTTGSAKAIAEIFPELK
CCCCCEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
GKLNGHAVRVPLLNGSLTDAVFELNKEVTTEQVNMALKEASETYLKGILGYEERPLVSAD
CCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC
YVNDSRSSIVDSLSTMVVNSNLLKIYAWYDNEWGYSCRLADLTEYVIKKEI
CCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEHHHHHHHHHHCCC
>Mature Secondary Structure
MYDLYRKNFKVMKIGINGFGRIGRLVFRALWDRADIEITHINEIAGDSNAAAHLLEFDSV
CCCCHHCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCHHHHHHHHHCC
HGRWEKDIKVKEEGIIIDGMKLTYTSFKNYLDVPWEKSSVDIILECTGKNKKPDKLNPYF
CCCCCCCCEEECCCEEEECCEEEHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCHH
DSLGMKRVIVACPVKGIVTGEEALNIVYGINQSLYDPSKHKLVTAASCTTNCLAPIVKVI
HHCCCCEEEEECCCCCEEECHHHEEEEEECCCHHCCCCCCCEEEECCHHHHHHHHHHHHH
NENFSIKHGAITTIHDVTNTQVPVDFYKSDLRRARGCMQSLIPTTTGSAKAIAEIFPELK
CCCCCEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
GKLNGHAVRVPLLNGSLTDAVFELNKEVTTEQVNMALKEASETYLKGILGYEERPLVSAD
CCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC
YVNDSRSSIVDSLSTMVVNSNLLKIYAWYDNEWGYSCRLADLTEYVIKKEI
CCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]