| Definition | Prochlorococcus marinus str. MIT 9312, complete genome. |
|---|---|
| Accession | NC_007577 |
| Length | 1,709,204 |
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The map label for this gene is purK [H]
Identifier: 78779068
GI number: 78779068
Start: 645011
End: 646201
Strand: Direct
Name: purK [H]
Synonym: PMT9312_0683
Alternate gene names: 78779068
Gene position: 645011-646201 (Clockwise)
Preceding gene: 78779066
Following gene: 78779073
Centisome position: 37.74
GC content: 30.81
Gene sequence:
>1191_bases ATGAGTTTAAAAAGAAATATAAACGATATTAAGAAAAATTATTCCCTAGGAATAATTGGAGGCGGTCAACTGGCTTTGAT GTTAACCGAGGCAGCACAAAAAAGAGATTTAGAAGTATGTGTGCAAACAAAATCTTGTGATGATCCTGCTGGTTTAAAAG CAGATCATGTCATAGAAGCTGATCCTTTAAAGATAAGAGGTAATAAATCGTTAATTAATGAGTGTGAAAAAATAATTTTT GAAAATGAATGGATAAAAATTGATAAATTAAATTTAATTGATAATAACGATATTTTTGTTCCAAGCCTTAATGCGATTAA GCCATTAGTAGATAGGTTTTCTCAAAAAAAATTAATAGATAGAATGAATATTCCCTGTCCAAAATGGATAAGTATTGAAG ATTTTAAAAATCTCCCTTATGAGGAAATCAGTAATTGGAGTTTCCCTTTAATGGCAAAATCAAATAAAGGTGGATATGAC GGTAAAGGGAACAGAAAAATAATGACAAAAGAAGATTTAGATTCTTTTTTAAAAGAGAATAATTCTGATGAATGGTTAAT AGAAGAATGGATAGAGTATGAAAAGGAACTAGCTCTTGTTGGTTCGAGAGATAGAACCGGTAAGATAAGATTCTTTCCAA TCGTTGAGACATTCCAATCAAATCATGTTTGTGATTGGGTTCTTGCACCTGCTACTACTGAATATGATTTGAACTTATTT GCAATAAATATTTTTTCCTCAATAGTCAATGAACTTAATTATGTTGGAGTTTTAGCTATTGAATTCTTCTATGGAGATAA TGGTCTTTTAATTAATGAAATAGCTCCAAGAACACATAACTCAGCACATTTCTCTATTGAAGCTTGTACTTCAAGTCAGT TTGATCAATATGTTTGCATTTCTTCTGGGATAATGCCACCTGAAATTAAAATGCACTCAGAAGGGGCAATTATGATAAAT CTACTGGGATTAAAAAAGAATTTCCCAATTTCAATAGAAACAAGAGTTAAAATGTTGTCTGAAATTGAGGGTTCTAATAT TCATTGTTATGGTAAATCTCGAGAAATTCTGGGGAGAAAAATGGCTCACATTACATTTTTATTGAACGGTAAAACGCATT CAGAAAGATATGATCAGGCACAAGTTTTATTAACTATGGTAAGAGACATTTGGCCATCTCCAAATACATAA
Upstream 100 bases:
>100_bases AAATATTTGGTATTAAGTACTATATATATTAGCAAAATCTAAGCTCTAGATACTTAAAAATTCAGTTGTTAAGAATTAGA AATCGTAATAAAATCATGCT
Downstream 100 bases:
>100_bases AAAAATAAGTTAGAGTTAAGTCACTGGATCTTTGGTTAAGTTCTTCTTTATGTGCTCTGATCTGACTTTCTTTCGACGTG AGGAGACTGTCGTGATGCGG
Product: phosphoribosylaminoimidazole carboxylase ATPase subunit
Products: NA
Alternate protein names: N5-CAIR synthase; 5-(carboxyamino)imidazole ribonucleotide synthetase [H]
Number of amino acids: Translated: 396; Mature: 395
Protein sequence:
>396_residues MSLKRNINDIKKNYSLGIIGGGQLALMLTEAAQKRDLEVCVQTKSCDDPAGLKADHVIEADPLKIRGNKSLINECEKIIF ENEWIKIDKLNLIDNNDIFVPSLNAIKPLVDRFSQKKLIDRMNIPCPKWISIEDFKNLPYEEISNWSFPLMAKSNKGGYD GKGNRKIMTKEDLDSFLKENNSDEWLIEEWIEYEKELALVGSRDRTGKIRFFPIVETFQSNHVCDWVLAPATTEYDLNLF AINIFSSIVNELNYVGVLAIEFFYGDNGLLINEIAPRTHNSAHFSIEACTSSQFDQYVCISSGIMPPEIKMHSEGAIMIN LLGLKKNFPISIETRVKMLSEIEGSNIHCYGKSREILGRKMAHITFLLNGKTHSERYDQAQVLLTMVRDIWPSPNT
Sequences:
>Translated_396_residues MSLKRNINDIKKNYSLGIIGGGQLALMLTEAAQKRDLEVCVQTKSCDDPAGLKADHVIEADPLKIRGNKSLINECEKIIF ENEWIKIDKLNLIDNNDIFVPSLNAIKPLVDRFSQKKLIDRMNIPCPKWISIEDFKNLPYEEISNWSFPLMAKSNKGGYD GKGNRKIMTKEDLDSFLKENNSDEWLIEEWIEYEKELALVGSRDRTGKIRFFPIVETFQSNHVCDWVLAPATTEYDLNLF AINIFSSIVNELNYVGVLAIEFFYGDNGLLINEIAPRTHNSAHFSIEACTSSQFDQYVCISSGIMPPEIKMHSEGAIMIN LLGLKKNFPISIETRVKMLSEIEGSNIHCYGKSREILGRKMAHITFLLNGKTHSERYDQAQVLLTMVRDIWPSPNT >Mature_395_residues SLKRNINDIKKNYSLGIIGGGQLALMLTEAAQKRDLEVCVQTKSCDDPAGLKADHVIEADPLKIRGNKSLINECEKIIFE NEWIKIDKLNLIDNNDIFVPSLNAIKPLVDRFSQKKLIDRMNIPCPKWISIEDFKNLPYEEISNWSFPLMAKSNKGGYDG KGNRKIMTKEDLDSFLKENNSDEWLIEEWIEYEKELALVGSRDRTGKIRFFPIVETFQSNHVCDWVLAPATTEYDLNLFA INIFSSIVNELNYVGVLAIEFFYGDNGLLINEIAPRTHNSAHFSIEACTSSQFDQYVCISSGIMPPEIKMHSEGAIMINL LGLKKNFPISIETRVKMLSEIEGSNIHCYGKSREILGRKMAHITFLLNGKTHSERYDQAQVLLTMVRDIWPSPNT
Specific function: Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) [H]
COG id: COG0026
COG function: function code F; Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ATP-grasp domain [H]
Homologues:
Organism=Escherichia coli, GI1786733, Length=354, Percent_Identity=25.9887005649718, Blast_Score=119, Evalue=4e-28, Organism=Saccharomyces cerevisiae, GI6324702, Length=377, Percent_Identity=30.7692307692308, Blast_Score=151, Evalue=1e-37,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005875 - InterPro: IPR011761 - InterPro: IPR003135 - InterPro: IPR013816 - InterPro: IPR013817 - InterPro: IPR016185 - InterPro: IPR011054 [H]
Pfam domain/function: PF02222 ATP-grasp [H]
EC number: =6.3.4.18 [H]
Molecular weight: Translated: 45102; Mature: 44971
Theoretical pI: Translated: 5.70; Mature: 5.70
Prosite motif: PS50975 ATP_GRASP
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 4.8 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 4.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSLKRNINDIKKNYSLGIIGGGQLALMLTEAAQKRDLEVCVQTKSCDDPAGLKADHVIEA CCCCCCHHHHHHCCEEEEEECCEEEEEEEHHHHHCCEEEEEEECCCCCCCCCCCCCEECC DPLKIRGNKSLINECEKIIFENEWIKIDKLNLIDNNDIFVPSLNAIKPLVDRFSQKKLID CCEEEECCHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHH RMNIPCPKWISIEDFKNLPYEEISNWSFPLMAKSNKGGYDGKGNRKIMTKEDLDSFLKEN HCCCCCCCCEEHHHHHCCCHHHHCCCCCEEEEECCCCCCCCCCCCEEECHHHHHHHHHCC NSDEWLIEEWIEYEKELALVGSRDRTGKIRFFPIVETFQSNHVCDWVLAPATTEYDLNLF CCCCHHHHHHHHHHHHEEEECCCCCCCCEEEEEEHHHHCCCCCEEEEECCCCCCCCCEEE AINIFSSIVNELNYVGVLAIEFFYGDNGLLINEIAPRTHNSAHFSIEACTSSQFDQYVCI EHHHHHHHHHHHCCEEEEEEEEEECCCCEEEECCCCCCCCCCEEEEEECCCCCCCCEEEE SSGIMPPEIKMHSEGAIMINLLGLKKNFPISIETRVKMLSEIEGSNIHCYGKSREILGRK CCCCCCCCEEECCCCEEEEEEEECCCCCCEEHHHHHHHHHHCCCCEEEEECCCHHHHHHE MAHITFLLNGKTHSERYDQAQVLLTMVRDIWPSPNT EEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCC >Mature Secondary Structure SLKRNINDIKKNYSLGIIGGGQLALMLTEAAQKRDLEVCVQTKSCDDPAGLKADHVIEA CCCCCHHHHHHCCEEEEEECCEEEEEEEHHHHHCCEEEEEEECCCCCCCCCCCCCEECC DPLKIRGNKSLINECEKIIFENEWIKIDKLNLIDNNDIFVPSLNAIKPLVDRFSQKKLID CCEEEECCHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHH RMNIPCPKWISIEDFKNLPYEEISNWSFPLMAKSNKGGYDGKGNRKIMTKEDLDSFLKEN HCCCCCCCCEEHHHHHCCCHHHHCCCCCEEEEECCCCCCCCCCCCEEECHHHHHHHHHCC NSDEWLIEEWIEYEKELALVGSRDRTGKIRFFPIVETFQSNHVCDWVLAPATTEYDLNLF CCCCHHHHHHHHHHHHEEEECCCCCCCCEEEEEEHHHHCCCCCEEEEECCCCCCCCCEEE AINIFSSIVNELNYVGVLAIEFFYGDNGLLINEIAPRTHNSAHFSIEACTSSQFDQYVCI EHHHHHHHHHHHCCEEEEEEEEEECCCCEEEECCCCCCCCCCEEEEEECCCCCCCCEEEE SSGIMPPEIKMHSEGAIMINLLGLKKNFPISIETRVKMLSEIEGSNIHCYGKSREILGRK CCCCCCCCEEECCCCEEEEEEEECCCCCCEEHHHHHHHHHHCCCCEEEEECCCHHHHHHE MAHITFLLNGKTHSERYDQAQVLLTMVRDIWPSPNT EEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA