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The map label for this gene is aroA [H]

Identifier: 78778998

GI number: 78778998

Start: 578414

End: 579724

Strand: Reverse

Name: aroA [H]

Synonym: PMT9312_0613

Alternate gene names: 78778998

Gene position: 579724-578414 (Counterclockwise)

Preceding gene: 78779005

Following gene: 78778997

Centisome position: 33.92

GC content: 36.46

Gene sequence:

>1311_bases
ATGAATAATGTCCGCAAAATAAAAGGTGGAAGTAATTTAAAAGGAAAAATAAAAGTACCTGGAGACAAATCTATTTCTCA
TAGAGCCTTGATAATAGGAAGTATTGCGCAGGGTGAAACGACTATTGAGGGTTTTTTACATTCTGAAGATCCACTTTCAA
CCGCTGATTGTCTTAGGAAATTAGGTGTAAACATACCAGACATAAAAGAAGATGAGCCTTTTACTATCTCAGGCTTGGGT
CTTGATGGAATAAAAGAGCCTAAAGAAATTCTTAATTGTGGAAATTCAGGAACCACCATGCGGTTATTAATGGGATTACT
AGCCGGTCAAGAAGGTAAAAATTTTATCTTGACAGGGGACACTTCTCTTAATGAGAGGCCAATGGGTAGAGTGAACAAAC
CATTATCTTTGATGGGTGGCATAATTTCTGGTAGAGAAAGCGGTAATAAAGCTCCAATCTCAATTTATGGAAATAAACTT
AAGGGATGTGTTATTGGAACTCCTATAGCAAGCGCTCAAGTAAAATCGGCAATATTATTGGCAGGCCTCAAAGCTTCTGG
AACTACTTCTGTTATTGAGCCTGCATCTTCAAGAGATCATACTGAAAGAATGTTAAAAGCATTTGGAGCGAACATAAGTA
TTAGAGGAGAATTAGGAAGGAATGTAGTAATAAAGTCAGGGGGTAATTTAATTGGGCAGAGAATATTAATCCCTGGAGAC
ATAAGCTCTGCATCCTTTTGGATGATTGCTGCATCTATTGTCCCAAATTCAGAGGTTTTAATTAAGAATGTTGGATTAAA
TCCCACTAGAACAGGGATATTAAATGTAATGGATTCAATGGGCTGCAATTATGAGATTTTAGATAAATCAACGATTGCAG
GAGAACCTATTGGATCTATTAAAGTAAAGACCGCAAATAATTTAAGATCATTCACTATTGAAGGAGATATTCTCCCAAAA
CTTATAGATGAAATTCCAATCCTTACTGTGGCAGCATGTTTTTGTAATGGAGTGTCTGAAATTAAGGATGCACAGGAATT
GAGATTTAAAGAAACAGACCGATTAAAAGTCATGGCAAGACAATTGAGCAAATTCGGTGCTGAAATAACAGAAAAAGAGG
ATGGATTAATAATTAATGGTCAATCAAAATTTCATTCTGCGGAAGTAGACAGTGAGACAGATCATCGAGTATCAATGAGT
CTTGCGATAGCTTCACTTGTCGCCAAAGGTACCTCAAAAATTATGAGAGCAGATGCATCTTACGTCTCATATCCATCTTT
TTGGGAAGACCTTGCCAAGTTAACTAACTAA

Upstream 100 bases:

>100_bases
ACAGTTACTTACTTTGAATATTTTTTTTTAAAAAACAAACTTATTGATAATATATATCTAATTTGTATTAATAAAAAATT
TATCAAGTATTAATTTGAAA

Downstream 100 bases:

>100_bases
CTCAAAAAGTTTTTGTCTGAATTAATAGAAGTTTTAACAAAAGATGGGAGTTACTCTTTAAGAAGTTTATTTTTTCAAGA
GAATTTCCATAGCTTATCGG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MNNVRKIKGGSNLKGKIKVPGDKSISHRALIIGSIAQGETTIEGFLHSEDPLSTADCLRKLGVNIPDIKEDEPFTISGLG
LDGIKEPKEILNCGNSGTTMRLLMGLLAGQEGKNFILTGDTSLNERPMGRVNKPLSLMGGIISGRESGNKAPISIYGNKL
KGCVIGTPIASAQVKSAILLAGLKASGTTSVIEPASSRDHTERMLKAFGANISIRGELGRNVVIKSGGNLIGQRILIPGD
ISSASFWMIAASIVPNSEVLIKNVGLNPTRTGILNVMDSMGCNYEILDKSTIAGEPIGSIKVKTANNLRSFTIEGDILPK
LIDEIPILTVAACFCNGVSEIKDAQELRFKETDRLKVMARQLSKFGAEITEKEDGLIINGQSKFHSAEVDSETDHRVSMS
LAIASLVAKGTSKIMRADASYVSYPSFWEDLAKLTN

Sequences:

>Translated_436_residues
MNNVRKIKGGSNLKGKIKVPGDKSISHRALIIGSIAQGETTIEGFLHSEDPLSTADCLRKLGVNIPDIKEDEPFTISGLG
LDGIKEPKEILNCGNSGTTMRLLMGLLAGQEGKNFILTGDTSLNERPMGRVNKPLSLMGGIISGRESGNKAPISIYGNKL
KGCVIGTPIASAQVKSAILLAGLKASGTTSVIEPASSRDHTERMLKAFGANISIRGELGRNVVIKSGGNLIGQRILIPGD
ISSASFWMIAASIVPNSEVLIKNVGLNPTRTGILNVMDSMGCNYEILDKSTIAGEPIGSIKVKTANNLRSFTIEGDILPK
LIDEIPILTVAACFCNGVSEIKDAQELRFKETDRLKVMARQLSKFGAEITEKEDGLIINGQSKFHSAEVDSETDHRVSMS
LAIASLVAKGTSKIMRADASYVSYPSFWEDLAKLTN
>Mature_436_residues
MNNVRKIKGGSNLKGKIKVPGDKSISHRALIIGSIAQGETTIEGFLHSEDPLSTADCLRKLGVNIPDIKEDEPFTISGLG
LDGIKEPKEILNCGNSGTTMRLLMGLLAGQEGKNFILTGDTSLNERPMGRVNKPLSLMGGIISGRESGNKAPISIYGNKL
KGCVIGTPIASAQVKSAILLAGLKASGTTSVIEPASSRDHTERMLKAFGANISIRGELGRNVVIKSGGNLIGQRILIPGD
ISSASFWMIAASIVPNSEVLIKNVGLNPTRTGILNVMDSMGCNYEILDKSTIAGEPIGSIKVKTANNLRSFTIEGDILPK
LIDEIPILTVAACFCNGVSEIKDAQELRFKETDRLKVMARQLSKFGAEITEKEDGLIINGQSKFHSAEVDSETDHRVSMS
LAIASLVAKGTSKIMRADASYVSYPSFWEDLAKLTN

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=434, Percent_Identity=28.110599078341, Blast_Score=130, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320332, Length=459, Percent_Identity=24.8366013071895, Blast_Score=113, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46535; Mature: 46535

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNVRKIKGGSNLKGKIKVPGDKSISHRALIIGSIAQGETTIEGFLHSEDPLSTADCLRK
CCCCEECCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCHHHHEECCCCCCCHHHHHHH
LGVNIPDIKEDEPFTISGLGLDGIKEPKEILNCGNSGTTMRLLMGLLAGQEGKNFILTGD
HCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECC
TSLNERPMGRVNKPLSLMGGIISGRESGNKAPISIYGNKLKGCVIGTPIASAQVKSAILL
CCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHE
AGLKASGTTSVIEPASSRDHTERMLKAFGANISIRGELGRNVVIKSGGNLIGQRILIPGD
EECCCCCCCHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCCEEEECCC
ISSASFWMIAASIVPNSEVLIKNVGLNPTRTGILNVMDSMGCNYEILDKSTIAGEPIGSI
CCCCEEEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCE
KVKTANNLRSFTIEGDILPKLIDEIPILTVAACFCNGVSEIKDAQELRFKETDRLKVMAR
EEEECCCCEEEEECCCHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHH
QLSKFGAEITEKEDGLIINGQSKFHSAEVDSETDHRVSMSLAIASLVAKGTSKIMRADAS
HHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
YVSYPSFWEDLAKLTN
CCCCCHHHHHHHHHCC
>Mature Secondary Structure
MNNVRKIKGGSNLKGKIKVPGDKSISHRALIIGSIAQGETTIEGFLHSEDPLSTADCLRK
CCCCEECCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCHHHHEECCCCCCCHHHHHHH
LGVNIPDIKEDEPFTISGLGLDGIKEPKEILNCGNSGTTMRLLMGLLAGQEGKNFILTGD
HCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECC
TSLNERPMGRVNKPLSLMGGIISGRESGNKAPISIYGNKLKGCVIGTPIASAQVKSAILL
CCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHE
AGLKASGTTSVIEPASSRDHTERMLKAFGANISIRGELGRNVVIKSGGNLIGQRILIPGD
EECCCCCCCHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCCEEEECCC
ISSASFWMIAASIVPNSEVLIKNVGLNPTRTGILNVMDSMGCNYEILDKSTIAGEPIGSI
CCCCEEEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCE
KVKTANNLRSFTIEGDILPKLIDEIPILTVAACFCNGVSEIKDAQELRFKETDRLKVMAR
EEEECCCCEEEEECCCHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHH
QLSKFGAEITEKEDGLIINGQSKFHSAEVDSETDHRVSMSLAIASLVAKGTSKIMRADAS
HHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
YVSYPSFWEDLAKLTN
CCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA