| Definition | Prochlorococcus marinus str. MIT 9312, complete genome. |
|---|---|
| Accession | NC_007577 |
| Length | 1,709,204 |
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The map label for this gene is murF [H]
Identifier: 78778995
GI number: 78778995
Start: 574747
End: 576120
Strand: Direct
Name: murF [H]
Synonym: PMT9312_0610
Alternate gene names: 78778995
Gene position: 574747-576120 (Clockwise)
Preceding gene: 78778994
Following gene: 78778999
Centisome position: 33.63
GC content: 28.31
Gene sequence:
>1374_bases ATGGAATTCTCTTTATCAGAATTGAAAAATGTTTTGGGGGATATTAAAAATCTGAAAGAGGGGGGGGAAGACTTTTTAAA TTTTAAAAATATAAGTATTGATAGTAGAACTATATTAAAAGATGATCTTTTTATAGCTATTAAGGGTAAGGATTTTGATG GACATAGTTTTCTTTCAGAGGTTTTAAAGAAAGGAGTTAAATCAGTAGTCATTAAAAAAGGGATGCAAAAATCACTCCCT ATTGATTTCCCTTGTTGGGTTGTAAATGACACATTAGAGGCATTTCAGAAATTAGCATTGCTAAAAAGAAAAAAATTAAA TATCCCTATAGTTGCAATAACTGGTTCAGTTGGTAAAACAACAACAAAAGAAATGATGGGTGAAGTTTTAAAGAAACTTG GAAGAATAAAACTATCCTATTCAAATTTCAATAATGAGATTGGAGTTGGTCTTACTATTCTTGATACAGATGTAGAAGAT AAAGTTTTAGTTCTTGAGATGGGAATGAGAGGTCTTGGACAAATCGAGAATTTATCTAAATATAGTGAACCCGATATTGC AGTTATTACTAACATTGGGACAGCTCATATTGGATTGTTAGGCTCGAAAAAGAATATTACTTATGCAAAGTGTGAAATTA GTAAGTTCTTAAATCCCAAAGGAGTTGTAATAATTCCAGCAAATGATTCATTACTAGAGGAAACTTTAAAAGAATTCTGG AAAGGTAGAGTAATAAAAGTAGAACTATTAAATATAGAAAATCAAAATGAGCGTTTTAAAAAAGATGATAATTTGCGAGG ATTTTATAATCCTTCGAATAAAACAATTTCAATTCAAGAAAATACCTTTGAAATTTCATTTGGGGGATTTCACAATGCTT CAAATTTCTTATTTGCTTATGGAGTTGCTAAAGAGCTTGGGATTGATTTCTCAAGTTTTAATAAGTTTAATTTTGCAAGC TTAGGCGGAAGGAATAAAATTCTTAAATCAGTTAAAACAACAATATATGATGAATCATATAATGCCTCGCCAGAGTCAGT AAAAGCATGTATTAAAACCCTGCTTGAAAAACCGAGAAATCAATTTTTCATATTTGGAAGTATGCAAGAATTAGGTGAAG AATCTGAAAAATATCATAAAGAAATATTCAACCTAATAAATAATTCAGACATAGAAAAGTGTTTATTTATTTGCGATAAA AAAAATGAAAGAATTTACGCTAATTATCTAAAAGACAACAAAAAATTTTTAGTTTTAAATAATATTAAAGATGTACCTAA AGAGATTAATAAATCTACAAAAAAAGGTGATTCAATTCTTATAAAAGGGAGCAGATGTTGGCAGCTTGAAAAAATTATTG AATTAATTAATTAG
Upstream 100 bases:
>100_bases CGGAATAAAGGAACCATCACCAGATGTTGCTGAAGTTGAAAAGTTCTCTTATGGACAATCTGCTGATCCATCATTAAAAA AAGGATGACTTAATATTTTA
Downstream 100 bases:
>100_bases ATCAAGGTTTCTTCCTTTCCCAATTATCTATATTAACTTGCTTAGTTCTTGAGATTGCTAATGAATTATCTTTGGAGTCT TTTGTTATCACTGAACCAGC
Product: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase
Products: NA
Alternate protein names: D-alanyl-D-alanine-adding enzyme; UDP-MurNAc-pentapeptide synthetase [H]
Number of amino acids: Translated: 457; Mature: 457
Protein sequence:
>457_residues MEFSLSELKNVLGDIKNLKEGGEDFLNFKNISIDSRTILKDDLFIAIKGKDFDGHSFLSEVLKKGVKSVVIKKGMQKSLP IDFPCWVVNDTLEAFQKLALLKRKKLNIPIVAITGSVGKTTTKEMMGEVLKKLGRIKLSYSNFNNEIGVGLTILDTDVED KVLVLEMGMRGLGQIENLSKYSEPDIAVITNIGTAHIGLLGSKKNITYAKCEISKFLNPKGVVIIPANDSLLEETLKEFW KGRVIKVELLNIENQNERFKKDDNLRGFYNPSNKTISIQENTFEISFGGFHNASNFLFAYGVAKELGIDFSSFNKFNFAS LGGRNKILKSVKTTIYDESYNASPESVKACIKTLLEKPRNQFFIFGSMQELGEESEKYHKEIFNLINNSDIEKCLFICDK KNERIYANYLKDNKKFLVLNNIKDVPKEINKSTKKGDSILIKGSRCWQLEKIIELIN
Sequences:
>Translated_457_residues MEFSLSELKNVLGDIKNLKEGGEDFLNFKNISIDSRTILKDDLFIAIKGKDFDGHSFLSEVLKKGVKSVVIKKGMQKSLP IDFPCWVVNDTLEAFQKLALLKRKKLNIPIVAITGSVGKTTTKEMMGEVLKKLGRIKLSYSNFNNEIGVGLTILDTDVED KVLVLEMGMRGLGQIENLSKYSEPDIAVITNIGTAHIGLLGSKKNITYAKCEISKFLNPKGVVIIPANDSLLEETLKEFW KGRVIKVELLNIENQNERFKKDDNLRGFYNPSNKTISIQENTFEISFGGFHNASNFLFAYGVAKELGIDFSSFNKFNFAS LGGRNKILKSVKTTIYDESYNASPESVKACIKTLLEKPRNQFFIFGSMQELGEESEKYHKEIFNLINNSDIEKCLFICDK KNERIYANYLKDNKKFLVLNNIKDVPKEINKSTKKGDSILIKGSRCWQLEKIIELIN >Mature_457_residues MEFSLSELKNVLGDIKNLKEGGEDFLNFKNISIDSRTILKDDLFIAIKGKDFDGHSFLSEVLKKGVKSVVIKKGMQKSLP IDFPCWVVNDTLEAFQKLALLKRKKLNIPIVAITGSVGKTTTKEMMGEVLKKLGRIKLSYSNFNNEIGVGLTILDTDVED KVLVLEMGMRGLGQIENLSKYSEPDIAVITNIGTAHIGLLGSKKNITYAKCEISKFLNPKGVVIIPANDSLLEETLKEFW KGRVIKVELLNIENQNERFKKDDNLRGFYNPSNKTISIQENTFEISFGGFHNASNFLFAYGVAKELGIDFSSFNKFNFAS LGGRNKILKSVKTTIYDESYNASPESVKACIKTLLEKPRNQFFIFGSMQELGEESEKYHKEIFNLINNSDIEKCLFICDK KNERIYANYLKDNKKFLVLNNIKDVPKEINKSTKKGDSILIKGSRCWQLEKIIELIN
Specific function: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein [H]
COG id: COG0770
COG function: function code M; UDP-N-acetylmuramyl pentapeptide synthase
Gene ontology:
Cell location: Cytoplasm (Probable) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family [H]
Homologues:
Organism=Escherichia coli, GI1786274, Length=470, Percent_Identity=26.3829787234043, Blast_Score=144, Evalue=2e-35,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR005863 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.10 [H]
Molecular weight: Translated: 51684; Mature: 51684
Theoretical pI: Translated: 9.39; Mature: 9.39
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEFSLSELKNVLGDIKNLKEGGEDFLNFKNISIDSRTILKDDLFIAIKGKDFDGHSFLSE CCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEECCEEEEEECCCCCHHHHHHH VLKKGVKSVVIKKGMQKSLPIDFPCWVVNDTLEAFQKLALLKRKKLNIPIVAITGSVGKT HHHHHHHHHHHHHCHHHCCCCCCCCEEECHHHHHHHHHHHHHHHCCCCEEEEEECCCCCH TTKEMMGEVLKKLGRIKLSYSNFNNEIGVGLTILDTDVEDKVLVLEMGMRGLGQIENLSK HHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHH YSEPDIAVITNIGTAHIGLLGSKKNITYAKCEISKFLNPKGVVIIPANDSLLEETLKEFW CCCCCEEEEEECCCEEEEEEECCCCCEEEEEEHHHCCCCCCEEEECCCHHHHHHHHHHHH KGRVIKVELLNIENQNERFKKDDNLRGFYNPSNKTISIQENTFEISFGGFHNASNFLFAY CCCEEEEEEEECCCCCCCCCCCCCCCCEECCCCCEEEEECCEEEEEECCCCCCCCEEEEE GVAKELGIDFSSFNKFNFASLGGRNKILKSVKTTIYDESYNASPESVKACIKTLLEKPRN ECHHHHCCCHHHCCCCCCHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC QFFIFGSMQELGEESEKYHKEIFNLINNSDIEKCLFICDKKNERIYANYLKDNKKFLVLN CEEEEECHHHHCHHHHHHHHHHHHHHCCCCHHHHHHEECCCCCEEEEEECCCCCCEEEEC NIKDVPKEINKSTKKGDSILIKGSRCWQLEKIIELIN CCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHC >Mature Secondary Structure MEFSLSELKNVLGDIKNLKEGGEDFLNFKNISIDSRTILKDDLFIAIKGKDFDGHSFLSE CCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEECCEEEEEECCCCCHHHHHHH VLKKGVKSVVIKKGMQKSLPIDFPCWVVNDTLEAFQKLALLKRKKLNIPIVAITGSVGKT HHHHHHHHHHHHHCHHHCCCCCCCCEEECHHHHHHHHHHHHHHHCCCCEEEEEECCCCCH TTKEMMGEVLKKLGRIKLSYSNFNNEIGVGLTILDTDVEDKVLVLEMGMRGLGQIENLSK HHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHH YSEPDIAVITNIGTAHIGLLGSKKNITYAKCEISKFLNPKGVVIIPANDSLLEETLKEFW CCCCCEEEEEECCCEEEEEEECCCCCEEEEEEHHHCCCCCCEEEECCCHHHHHHHHHHHH KGRVIKVELLNIENQNERFKKDDNLRGFYNPSNKTISIQENTFEISFGGFHNASNFLFAY CCCEEEEEEEECCCCCCCCCCCCCCCCEECCCCCEEEEECCEEEEEECCCCCCCCEEEEE GVAKELGIDFSSFNKFNFASLGGRNKILKSVKTTIYDESYNASPESVKACIKTLLEKPRN ECHHHHCCCHHHCCCCCCHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC QFFIFGSMQELGEESEKYHKEIFNLINNSDIEKCLFICDKKNERIYANYLKDNKKFLVLN CEEEEECHHHHCHHHHHHHHHHHHHHCCCCHHHHHHEECCCCCEEEEEECCCCCCEEEEC NIKDVPKEINKSTKKGDSILIKGSRCWQLEKIIELIN CCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7894708; 8905231 [H]