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The map label for this gene is trpS [H]

Identifier: 78778983

GI number: 78778983

Start: 562890

End: 563906

Strand: Reverse

Name: trpS [H]

Synonym: PMT9312_0598

Alternate gene names: 78778983

Gene position: 563906-562890 (Counterclockwise)

Preceding gene: 78778984

Following gene: 78778982

Centisome position: 32.99

GC content: 31.96

Gene sequence:

>1017_bases
ATGACAAATAAAAAAAGGATTCTTTCGGGAGTCCAACCAACTGGTGATTTACATATAGGAAATTGGCTTGGAGCAATCAA
TAATTGGGTGACACTTCAAGAGGAATATGAAACATTTCTATGTGTAGTTGATTTGCACGCAATAACAGCCGCATATAATC
CCAAAGAATTATCTAAAAATACTATCTCTACCGCCGCTTTGTACGTTGCTTGTGGGATAGATCCCAAAATATGCTCAATT
TTCGTTCAAAGTCAGATTTCTGCACATTCAGAACTTTGTTGGATATTAAATTGCATGACTCCTATAAATTGGATGGAAAG
AATGATTCAATTCAAAGAAAAATCCATACAACAGGGAAATAATGTATCTATTGGATTATTTGACTATCCAATCCTGATGG
CTGCAGACATCCTCCTATACGATGCAGACTACGTACCAGTAGGTGAGGATCAAAAACAACATCTTGAACTTGCTAGAGAT
ATTGCACAACAAAGAATTAATGCCAAATTTAGTAAAGATAAAAATATTTTGAAAATTCCTCAGCCAATAATTATGAAGAA
TGGATCAAAAATAATGAGTTTAGTTGATGGTTCAAAAAAGATGAGCAAAAGTGATCCTAATGAGGGCAGTCGCATTAACT
TATTAGATCCTCCTGAAATAATCACAAAAAAAATAAAAAGAGCAAAAAGTGACAGTTCTATTGGAATTGAATTTAACAAC
CCAGAGAGACCAGAATCTAAAAATCTTTTGATGATTTATTCAATATTATCTGGCAAAGAAATTTCTCAATGCGAAAATGA
ATTCTCAGAGACTGGATGGGGGACATTTAAAAAATTAATTACTGAAAAACTCATTGAATCACTAGAACCTATTCAGAAAA
AATATAAATTATTAATTAATGATCCTTATCAATTAAATAACATCCTTGATGAAGGGAAGGAAAAAGCTGAAGATTTAGCA
AATCAGACTTTAAAAAGAGTTAAATCAAAATTGGGATTCTTTGAAATGGAGAAATAA

Upstream 100 bases:

>100_bases
AAACCTTATGAAGAAAATACAAAAAAAACACCTGACCCCTTTGCAAGACCTGTCAAAAGTACCTCAAATGAAGAAATCCA
ATCTAGCGAATTAGAAAAGG

Downstream 100 bases:

>100_bases
ATTATGCCAATAATTACCTTGCCTGATGGTTCAAAAAAGGTTTTCGAAAAATCTGTAACTATTCTAGAAATTGCCCAGAG
TATAGGTGCTGGATTAGCTA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTNKKRILSGVQPTGDLHIGNWLGAINNWVTLQEEYETFLCVVDLHAITAAYNPKELSKNTISTAALYVACGIDPKICSI
FVQSQISAHSELCWILNCMTPINWMERMIQFKEKSIQQGNNVSIGLFDYPILMAADILLYDADYVPVGEDQKQHLELARD
IAQQRINAKFSKDKNILKIPQPIIMKNGSKIMSLVDGSKKMSKSDPNEGSRINLLDPPEIITKKIKRAKSDSSIGIEFNN
PERPESKNLLMIYSILSGKEISQCENEFSETGWGTFKKLITEKLIESLEPIQKKYKLLINDPYQLNNILDEGKEKAEDLA
NQTLKRVKSKLGFFEMEK

Sequences:

>Translated_338_residues
MTNKKRILSGVQPTGDLHIGNWLGAINNWVTLQEEYETFLCVVDLHAITAAYNPKELSKNTISTAALYVACGIDPKICSI
FVQSQISAHSELCWILNCMTPINWMERMIQFKEKSIQQGNNVSIGLFDYPILMAADILLYDADYVPVGEDQKQHLELARD
IAQQRINAKFSKDKNILKIPQPIIMKNGSKIMSLVDGSKKMSKSDPNEGSRINLLDPPEIITKKIKRAKSDSSIGIEFNN
PERPESKNLLMIYSILSGKEISQCENEFSETGWGTFKKLITEKLIESLEPIQKKYKLLINDPYQLNNILDEGKEKAEDLA
NQTLKRVKSKLGFFEMEK
>Mature_337_residues
TNKKRILSGVQPTGDLHIGNWLGAINNWVTLQEEYETFLCVVDLHAITAAYNPKELSKNTISTAALYVACGIDPKICSIF
VQSQISAHSELCWILNCMTPINWMERMIQFKEKSIQQGNNVSIGLFDYPILMAADILLYDADYVPVGEDQKQHLELARDI
AQQRINAKFSKDKNILKIPQPIIMKNGSKIMSLVDGSKKMSKSDPNEGSRINLLDPPEIITKKIKRAKSDSSIGIEFNNP
ERPESKNLLMIYSILSGKEISQCENEFSETGWGTFKKLITEKLIESLEPIQKKYKLLINDPYQLNNILDEGKEKAEDLAN
QTLKRVKSKLGFFEMEK

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=333, Percent_Identity=37.2372372372372, Blast_Score=248, Evalue=5e-66,
Organism=Homo sapiens, GI41352700, Length=183, Percent_Identity=45.9016393442623, Blast_Score=181, Evalue=1e-45,
Organism=Escherichia coli, GI1789786, Length=329, Percent_Identity=45.2887537993921, Blast_Score=301, Evalue=5e-83,
Organism=Caenorhabditis elegans, GI71982800, Length=335, Percent_Identity=34.0298507462687, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI71982793, Length=335, Percent_Identity=34.3283582089552, Blast_Score=183, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6320474, Length=350, Percent_Identity=38.5714285714286, Blast_Score=209, Evalue=5e-55,
Organism=Drosophila melanogaster, GI24666151, Length=333, Percent_Identity=39.6396396396396, Blast_Score=250, Evalue=9e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 38318; Mature: 38187

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKKRILSGVQPTGDLHIGNWLGAINNWVTLQEEYETFLCVVDLHAITAAYNPKELSKN
CCCHHHHHCCCCCCCCEEHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TISTAALYVACGIDPKICSIFVQSQISAHSELCWILNCMTPINWMERMIQFKEKSIQQGN
HHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC
NVSIGLFDYPILMAADILLYDADYVPVGEDQKQHLELARDIAQQRINAKFSKDKNILKIP
CEEEEEECCHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCCCCEEECC
QPIIMKNGSKIMSLVDGSKKMSKSDPNEGSRINLLDPPEIITKKIKRAKSDSSIGIEFNN
CHHHHCCCHHHHHHHCCCHHHCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCEEEEECC
PERPESKNLLMIYSILSGKEISQCENEFSETGWGTFKKLITEKLIESLEPIQKKYKLLIN
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPYQLNNILDEGKEKAEDLANQTLKRVKSKLGFFEMEK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC
>Mature Secondary Structure 
TNKKRILSGVQPTGDLHIGNWLGAINNWVTLQEEYETFLCVVDLHAITAAYNPKELSKN
CCHHHHHCCCCCCCCEEHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TISTAALYVACGIDPKICSIFVQSQISAHSELCWILNCMTPINWMERMIQFKEKSIQQGN
HHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC
NVSIGLFDYPILMAADILLYDADYVPVGEDQKQHLELARDIAQQRINAKFSKDKNILKIP
CEEEEEECCHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCCCCEEECC
QPIIMKNGSKIMSLVDGSKKMSKSDPNEGSRINLLDPPEIITKKIKRAKSDSSIGIEFNN
CHHHHCCCHHHHHHHCCCHHHCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCEEEEECC
PERPESKNLLMIYSILSGKEISQCENEFSETGWGTFKKLITEKLIESLEPIQKKYKLLIN
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPYQLNNILDEGKEKAEDLANQTLKRVKSKLGFFEMEK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]