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The map label for this gene is pcrA [H]

Identifier: 78778691

GI number: 78778691

Start: 291366

End: 293774

Strand: Reverse

Name: pcrA [H]

Synonym: PMT9312_0306

Alternate gene names: 78778691

Gene position: 293774-291366 (Counterclockwise)

Preceding gene: 78778693

Following gene: 78778690

Centisome position: 17.19

GC content: 32.79

Gene sequence:

>2409_bases
GTGCCTCAAACCAACAATTTCCTTTTTAAGTCCCTAAACAAACAACAACTTCAAGCAGTAAAACATGTTTATGGACCACT
ATTAGTTGTAGCAGGTGCAGGTAGCGGAAAAACTAAGGCTCTTACTCACAGAATTGCAAACCTTATAGAGGGTAACTCTA
TAGATCCCTATAACATTCTGGCAGTCACTTTCACTAACAAAGCTGCTAAAGAAATGAAAGCAAGATTAGAGGTTCTTCTA
GCCCAAGAATTAGCTTTTAATCAATTTGGTCAGCCTTGGACAACTCTCAAAGAAATTGATCAAAATCAATTAAGAACAAA
CGTTCACCAAGAGAGGCTTCAGAACCTTTGGATCGGTACTTTCCATTCTTTATTTTCAAGACTTCTGAGATACGATATTG
AAAAATATACTGATCCAGAAGGCCTAAAATGGACGAGGCAATTTTCAATTTACGATGAAACAGATTCTCAAACATTAGTA
AAAGAAATTATCAGTCAAGATATGAATCTTGACCCAAAAAGATATGATCCCAAAAAGATTAAAAGATTAATAAGTAATGC
TAAAAATCAATGCTTAACTTCTAATGATCTTTTAGAAAAAGCAGATAATAATTTTGATAAAACAGTTGCAGAAGCCTACA
GGAGATATAGAATTTCGCTTTCAAAAAATAATTCTTTAGATTTTGATGATCTTCTACTTTTGCCTGTTTTCTTATTAAGA
CAAAATGATATGGTCAGAGATTACTGGCACAAAAGATTTAAACATATTTTAGTTGACGAATATCAAGATACAAATAGAAC
ACAATATGAACTTATAAAATTAATTACGGCTGGAAATACTGAACCAAAAAAATTCTTCAATTGGGAAGATCGGTCAATTT
TTGTAGTTGGGGATGCTGATCAAAGTATTTATAGTTTCAGAGCAGCTGACTTCAGAATTTTAATTGGTTTTCAAGAAGAT
TTTAAAACTTCAATCAACGACGATACAAAATCATCTTTAATTAAATTAGAAGAAAATTATAGGTCATCTTCTAATATCCT
TGATGCTGCAAACTCACTAATTGAAAACAACTCTGAAAGAATTGACAAAGTTTTAAAGGCTACTAAAGAAAAAGGGGAAC
TTTTAACGTTACTCAGCTGTGATGATGAAATTTCCGAGGCAGAAGCAATTACCAATAAAATAAAATCACTCAATAACTAT
AATCAAAACCCAATTTGGAAAAATTTTGCAATTTTATATCGAACCAGGGCTCAGTCAAGAGTATTAGAAGAATCTCTTGT
AAGGTGGCGCATTCCTTATACAATTTTTGGAGGATTGCGTTTTTATGATAGAAGAGAAATTAAAGATGCAATAGCATATT
TGAAAGTTCTGGTTAATTCTTCAGATAACGTTAGTCTTTTGCGAATCATAAATGTTCCTAGAAGAGGGATTGGTAAGACT
ACTATTCAAAAACTTAATGAATTATCTAATAGGTTAAATATCCCATTATGGGAGGTTCTTAATGATAAGCAAAGTCTTGA
AGAAACAATAGGCCGATCATCAAAAGGAATTAATAAATTTACTGAAGTTATGAATGATCTACTGTGTTACCTAGAAAATT
CAGGCCCCGCTCAACTACTACAACTTATATTAGAAAAAAGTGGTTATTTAAGTGACTTGCTCTCTAATGGGACTGAAGAA
TCTGAAGATAGAAGAAATAACTTACAAGAACTAATTAATGCAGCTACTCAATATGAAGAAGAAACAGAAAGTGGGGATGT
AGAGGGATTTCTTTCTACAGCAGCCTTAACAACTGATAATGATACGAAAAAAAATAATCCCAACTCTGTAACTCTCATGA
CTCTGCATAATAGTAAAGGTTTAGAATTTCAAAATGTTTTTATCACTGGGCTAGAACAAGGTCTCTTCCCTAGCCATAGA
TCAATAGATACTCCCTCACTTCTTGAAGAGGAAAGAAGATTATGCTATGTAGGTATTACTAGAGCTAAAGAAAGAGTTTT
CTTAAGTCATGCTAGAGAAAGAAGATTATGGGGTGGAATGCGTGAAGCAACAATTCCTTCAATATTTCTTTCAGAAATAC
CTGAAGATTTAATGGATGGCGAATTACCACAAACTGGTGGTGCTTCAATTAGAAGAGATTGGCATCTTGAACGTTTAACT
AGAGTTGATCGAAACAATCCAAATGAATTTGTTAACAAACCAATAAATGCAGTAAGGAAATTATATTCAGGTCCCAGTAA
AGGGAAAAGCTGGATAGTTGGAGATAAGCTAATTCACTCAAAGTTTGGGAAAGGTGAAATCATACATATTTTTGGGAGTG
GGGAAAAAATATCTTTAGCAGTAAAATTTGGTGATAAAGGAAGTAAAATTCTAGATCCCAGATTAGCTCCAATTCGTTAT
GTAAGTTAA

Upstream 100 bases:

>100_bases
AACAATAATGAACTTATGAACTTAAAAAAAGCGTTAGAAGATCTAGAAACGGAATCTGAATCTCATACTAAAGTCTGATT
TTTGAAAAACCCTTCCAAAA

Downstream 100 bases:

>100_bases
AACTCATGAACGATATCTCTGATTACATCCAAGGAGAATTAATAAAAACTCCATTTAATCTATATAACCTAATTGCTAAA
TACATAGAATCTAATAACAA

Product: ATP-dependent DNA helicase Rep

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 802; Mature: 801

Protein sequence:

>802_residues
MPQTNNFLFKSLNKQQLQAVKHVYGPLLVVAGAGSGKTKALTHRIANLIEGNSIDPYNILAVTFTNKAAKEMKARLEVLL
AQELAFNQFGQPWTTLKEIDQNQLRTNVHQERLQNLWIGTFHSLFSRLLRYDIEKYTDPEGLKWTRQFSIYDETDSQTLV
KEIISQDMNLDPKRYDPKKIKRLISNAKNQCLTSNDLLEKADNNFDKTVAEAYRRYRISLSKNNSLDFDDLLLLPVFLLR
QNDMVRDYWHKRFKHILVDEYQDTNRTQYELIKLITAGNTEPKKFFNWEDRSIFVVGDADQSIYSFRAADFRILIGFQED
FKTSINDDTKSSLIKLEENYRSSSNILDAANSLIENNSERIDKVLKATKEKGELLTLLSCDDEISEAEAITNKIKSLNNY
NQNPIWKNFAILYRTRAQSRVLEESLVRWRIPYTIFGGLRFYDRREIKDAIAYLKVLVNSSDNVSLLRIINVPRRGIGKT
TIQKLNELSNRLNIPLWEVLNDKQSLEETIGRSSKGINKFTEVMNDLLCYLENSGPAQLLQLILEKSGYLSDLLSNGTEE
SEDRRNNLQELINAATQYEEETESGDVEGFLSTAALTTDNDTKKNNPNSVTLMTLHNSKGLEFQNVFITGLEQGLFPSHR
SIDTPSLLEEERRLCYVGITRAKERVFLSHARERRLWGGMREATIPSIFLSEIPEDLMDGELPQTGGASIRRDWHLERLT
RVDRNNPNEFVNKPINAVRKLYSGPSKGKSWIVGDKLIHSKFGKGEIIHIFGSGEKISLAVKFGDKGSKILDPRLAPIRY
VS

Sequences:

>Translated_802_residues
MPQTNNFLFKSLNKQQLQAVKHVYGPLLVVAGAGSGKTKALTHRIANLIEGNSIDPYNILAVTFTNKAAKEMKARLEVLL
AQELAFNQFGQPWTTLKEIDQNQLRTNVHQERLQNLWIGTFHSLFSRLLRYDIEKYTDPEGLKWTRQFSIYDETDSQTLV
KEIISQDMNLDPKRYDPKKIKRLISNAKNQCLTSNDLLEKADNNFDKTVAEAYRRYRISLSKNNSLDFDDLLLLPVFLLR
QNDMVRDYWHKRFKHILVDEYQDTNRTQYELIKLITAGNTEPKKFFNWEDRSIFVVGDADQSIYSFRAADFRILIGFQED
FKTSINDDTKSSLIKLEENYRSSSNILDAANSLIENNSERIDKVLKATKEKGELLTLLSCDDEISEAEAITNKIKSLNNY
NQNPIWKNFAILYRTRAQSRVLEESLVRWRIPYTIFGGLRFYDRREIKDAIAYLKVLVNSSDNVSLLRIINVPRRGIGKT
TIQKLNELSNRLNIPLWEVLNDKQSLEETIGRSSKGINKFTEVMNDLLCYLENSGPAQLLQLILEKSGYLSDLLSNGTEE
SEDRRNNLQELINAATQYEEETESGDVEGFLSTAALTTDNDTKKNNPNSVTLMTLHNSKGLEFQNVFITGLEQGLFPSHR
SIDTPSLLEEERRLCYVGITRAKERVFLSHARERRLWGGMREATIPSIFLSEIPEDLMDGELPQTGGASIRRDWHLERLT
RVDRNNPNEFVNKPINAVRKLYSGPSKGKSWIVGDKLIHSKFGKGEIIHIFGSGEKISLAVKFGDKGSKILDPRLAPIRY
VS
>Mature_801_residues
PQTNNFLFKSLNKQQLQAVKHVYGPLLVVAGAGSGKTKALTHRIANLIEGNSIDPYNILAVTFTNKAAKEMKARLEVLLA
QELAFNQFGQPWTTLKEIDQNQLRTNVHQERLQNLWIGTFHSLFSRLLRYDIEKYTDPEGLKWTRQFSIYDETDSQTLVK
EIISQDMNLDPKRYDPKKIKRLISNAKNQCLTSNDLLEKADNNFDKTVAEAYRRYRISLSKNNSLDFDDLLLLPVFLLRQ
NDMVRDYWHKRFKHILVDEYQDTNRTQYELIKLITAGNTEPKKFFNWEDRSIFVVGDADQSIYSFRAADFRILIGFQEDF
KTSINDDTKSSLIKLEENYRSSSNILDAANSLIENNSERIDKVLKATKEKGELLTLLSCDDEISEAEAITNKIKSLNNYN
QNPIWKNFAILYRTRAQSRVLEESLVRWRIPYTIFGGLRFYDRREIKDAIAYLKVLVNSSDNVSLLRIINVPRRGIGKTT
IQKLNELSNRLNIPLWEVLNDKQSLEETIGRSSKGINKFTEVMNDLLCYLENSGPAQLLQLILEKSGYLSDLLSNGTEES
EDRRNNLQELINAATQYEEETESGDVEGFLSTAALTTDNDTKKNNPNSVTLMTLHNSKGLEFQNVFITGLEQGLFPSHRS
IDTPSLLEEERRLCYVGITRAKERVFLSHARERRLWGGMREATIPSIFLSEIPEDLMDGELPQTGGASIRRDWHLERLTR
VDRNNPNEFVNKPINAVRKLYSGPSKGKSWIVGDKLIHSKFGKGEIIHIFGSGEKISLAVKFGDKGSKILDPRLAPIRYV
S

Specific function: Essential helicase [H]

COG id: COG0210

COG function: function code L; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367296, Length=790, Percent_Identity=34.9367088607595, Blast_Score=437, Evalue=1e-123,
Organism=Escherichia coli, GI48994965, Length=693, Percent_Identity=36.7965367965368, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1787196, Length=428, Percent_Identity=27.1028037383178, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322369, Length=782, Percent_Identity=27.8772378516624, Blast_Score=207, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6324477, Length=732, Percent_Identity=23.6338797814208, Blast_Score=113, Evalue=1e-25,

Paralogues:

None

Copy number: 3000 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005751
- InterPro:   IPR013986
- InterPro:   IPR014017
- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 92045; Mature: 91913

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQTNNFLFKSLNKQQLQAVKHVYGPLLVVAGAGSGKTKALTHRIANLIEGNSIDPYNIL
CCCCCCHHHHHCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEE
AVTFTNKAAKEMKARLEVLLAQELAFNQFGQPWTTLKEIDQNQLRTNVHQERLQNLWIGT
EEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHSLFSRLLRYDIEKYTDPEGLKWTRQFSIYDETDSQTLVKEIISQDMNLDPKRYDPKKI
HHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHH
KRLISNAKNQCLTSNDLLEKADNNFDKTVAEAYRRYRISLSKNNSLDFDDLLLLPVFLLR
HHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHC
QNDMVRDYWHKRFKHILVDEYQDTNRTQYELIKLITAGNTEPKKFFNWEDRSIFVVGDAD
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEECCC
QSIYSFRAADFRILIGFQEDFKTSINDDTKSSLIKLEENYRSSSNILDAANSLIENNSER
CHHHHHHCCCEEEEEEEHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHH
IDKVLKATKEKGELLTLLSCDDEISEAEAITNKIKSLNNYNQNPIWKNFAILYRTRAQSR
HHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VLEESLVRWRIPYTIFGGLRFYDRREIKDAIAYLKVLVNSSDNVSLLRIINVPRRGIGKT
HHHHHHHHEECCHHEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHH
TIQKLNELSNRLNIPLWEVLNDKQSLEETIGRSSKGINKFTEVMNDLLCYLENSGPAQLL
HHHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
QLILEKSGYLSDLLSNGTEESEDRRNNLQELINAATQYEEETESGDVEGFLSTAALTTDN
HHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEECCC
DTKKNNPNSVTLMTLHNSKGLEFQNVFITGLEQGLFPSHRSIDTPSLLEEERRLCYVGIT
CCCCCCCCEEEEEEEECCCCCEEHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEEEHH
RAKERVFLSHARERRLWGGMREATIPSIFLSEIPEDLMDGELPQTGGASIRRDWHLERLT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHH
RVDRNNPNEFVNKPINAVRKLYSGPSKGKSWIVGDKLIHSKFGKGEIIHIFGSGEKISLA
HHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHCCCCCCEEEEEECCCEEEEE
VKFGDKGSKILDPRLAPIRYVS
EEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PQTNNFLFKSLNKQQLQAVKHVYGPLLVVAGAGSGKTKALTHRIANLIEGNSIDPYNIL
CCCCCHHHHHCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEE
AVTFTNKAAKEMKARLEVLLAQELAFNQFGQPWTTLKEIDQNQLRTNVHQERLQNLWIGT
EEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHSLFSRLLRYDIEKYTDPEGLKWTRQFSIYDETDSQTLVKEIISQDMNLDPKRYDPKKI
HHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHH
KRLISNAKNQCLTSNDLLEKADNNFDKTVAEAYRRYRISLSKNNSLDFDDLLLLPVFLLR
HHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHC
QNDMVRDYWHKRFKHILVDEYQDTNRTQYELIKLITAGNTEPKKFFNWEDRSIFVVGDAD
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEECCC
QSIYSFRAADFRILIGFQEDFKTSINDDTKSSLIKLEENYRSSSNILDAANSLIENNSER
CHHHHHHCCCEEEEEEEHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHH
IDKVLKATKEKGELLTLLSCDDEISEAEAITNKIKSLNNYNQNPIWKNFAILYRTRAQSR
HHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VLEESLVRWRIPYTIFGGLRFYDRREIKDAIAYLKVLVNSSDNVSLLRIINVPRRGIGKT
HHHHHHHHEECCHHEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHH
TIQKLNELSNRLNIPLWEVLNDKQSLEETIGRSSKGINKFTEVMNDLLCYLENSGPAQLL
HHHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
QLILEKSGYLSDLLSNGTEESEDRRNNLQELINAATQYEEETESGDVEGFLSTAALTTDN
HHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEECCC
DTKKNNPNSVTLMTLHNSKGLEFQNVFITGLEQGLFPSHRSIDTPSLLEEERRLCYVGIT
CCCCCCCCEEEEEEEECCCCCEEHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEEEHH
RAKERVFLSHARERRLWGGMREATIPSIFLSEIPEDLMDGELPQTGGASIRRDWHLERLT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHH
RVDRNNPNEFVNKPINAVRKLYSGPSKGKSWIVGDKLIHSKFGKGEIIHIFGSGEKISLA
HHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHCCCCCCEEEEEECCCEEEEE
VKFGDKGSKILDPRLAPIRYVS
EEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA