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The map label for this gene is aroC [H]

Identifier: 78778612

GI number: 78778612

Start: 218769

End: 219866

Strand: Direct

Name: aroC [H]

Synonym: PMT9312_0226

Alternate gene names: 78778612

Gene position: 218769-219866 (Clockwise)

Preceding gene: 78778611

Following gene: 78778619

Centisome position: 12.8

GC content: 36.89

Gene sequence:

>1098_bases
ATGAGTAGTAGTTTTGGAAAAATTTTTCGGGTTAGTACTTTTGGAGAATCACATGGCGGTGGAGTAGGAGTTATCCTTGA
TGGATGTCCACCTAAGTTAAAAATAGATATAAAACTGATACAAAATGAATTAGATAGGCGTAGACCTGGTCAAAGTGACA
TTACAACACCACGAAATGAAGACGATAAAATTGAGATATTAAGTGGGATAAAGGAAGGTTTAACACTTGGAACTCCAATA
GCGATGTTGGTAAGAAACAAGGATCAAAGACCAGGAGATTATAATAATTTGGAGCAAGTATTTAGACCATCTCATGCAGA
TGGTACATATCATCTGAAATATGGAATTCAGGCTGGTTCTGGAGGTGGAAGAGCGTCTGCAAGAGAAACAATTGGGCGAG
TAGCAGCTGGTGCTGTAGCAAAACAATTATTAAAAAACTTGTGTAACACTGAAATATTATCTTGGGTAAAGCGTATACAT
GATATTGATTCTGATGTAAATAAAGAGAAGATTTCTCTCAATAAAATAGATTCTAATATTGTCAGATGTCCTGATGAAAA
GGTATCAGCAGAAATGATCGATAGAATTAAGGATTTAAAGCGTCAAGGAGACTCTTGTGGAGGTGTAATTGAATGTCTGG
TAAGGAATGTTCCGTCTGGTCTTGGGATGCCTGTTTTTGATAAATTGGAAGCTGATTTAGCGAAGGCTTTGATGTCTTTG
CCAGCCACGAAAGGCTTTGAAATAGGTTCAGGTTTCTCTGGAACTTATTTAAAAGGAAGCGAACATAATGATTCATTCAT
TAAGTCTGATGATATTAGTAAGTTAAGAACAACATCTAACAATTCAGGAGGTATACAGGGCGGAATAAGTAATGGAGAAA
ATATTGAGATGAAGATAGCTTTTAAACCCACAGCAACCATTGGGAAAGAACAGAAAACCGTAAATGCTGAAGGGAAAGAA
GTATTGATGAAAGCAAAAGGGAGACATGATCCATGCGTTCTACCAAGAGCAGTTCCTATGGTTGACGCTATGGTCGCTTT
AGTACTTGCTGATCATTTGCTTCTGAATAATGCTCAATGTGGATTAATGAAAAATTAG

Upstream 100 bases:

>100_bases
TTCTTAATTTTACAAGCCCCCTTTTTGGGGGCTTTTTTTTGTTTAATTTTCAATTATTTTCATATAATGTTTATATATAG
ATAAAACATTTGATATTTCT

Downstream 100 bases:

>100_bases
TAGTTTTGTTGAATCAATTATATTTGTCCTTAATTTAACTATTTTCGAGCCATTCAAATATTTTTGGATCAAAATTTTTA
TTTTTTATACCTTTATCTCC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSSSFGKIFRVSTFGESHGGGVGVILDGCPPKLKIDIKLIQNELDRRRPGQSDITTPRNEDDKIEILSGIKEGLTLGTPI
AMLVRNKDQRPGDYNNLEQVFRPSHADGTYHLKYGIQAGSGGGRASARETIGRVAAGAVAKQLLKNLCNTEILSWVKRIH
DIDSDVNKEKISLNKIDSNIVRCPDEKVSAEMIDRIKDLKRQGDSCGGVIECLVRNVPSGLGMPVFDKLEADLAKALMSL
PATKGFEIGSGFSGTYLKGSEHNDSFIKSDDISKLRTTSNNSGGIQGGISNGENIEMKIAFKPTATIGKEQKTVNAEGKE
VLMKAKGRHDPCVLPRAVPMVDAMVALVLADHLLLNNAQCGLMKN

Sequences:

>Translated_365_residues
MSSSFGKIFRVSTFGESHGGGVGVILDGCPPKLKIDIKLIQNELDRRRPGQSDITTPRNEDDKIEILSGIKEGLTLGTPI
AMLVRNKDQRPGDYNNLEQVFRPSHADGTYHLKYGIQAGSGGGRASARETIGRVAAGAVAKQLLKNLCNTEILSWVKRIH
DIDSDVNKEKISLNKIDSNIVRCPDEKVSAEMIDRIKDLKRQGDSCGGVIECLVRNVPSGLGMPVFDKLEADLAKALMSL
PATKGFEIGSGFSGTYLKGSEHNDSFIKSDDISKLRTTSNNSGGIQGGISNGENIEMKIAFKPTATIGKEQKTVNAEGKE
VLMKAKGRHDPCVLPRAVPMVDAMVALVLADHLLLNNAQCGLMKN
>Mature_364_residues
SSSFGKIFRVSTFGESHGGGVGVILDGCPPKLKIDIKLIQNELDRRRPGQSDITTPRNEDDKIEILSGIKEGLTLGTPIA
MLVRNKDQRPGDYNNLEQVFRPSHADGTYHLKYGIQAGSGGGRASARETIGRVAAGAVAKQLLKNLCNTEILSWVKRIHD
IDSDVNKEKISLNKIDSNIVRCPDEKVSAEMIDRIKDLKRQGDSCGGVIECLVRNVPSGLGMPVFDKLEADLAKALMSLP
ATKGFEIGSGFSGTYLKGSEHNDSFIKSDDISKLRTTSNNSGGIQGGISNGENIEMKIAFKPTATIGKEQKTVNAEGKEV
LMKAKGRHDPCVLPRAVPMVDAMVALVLADHLLLNNAQCGLMKN

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=357, Percent_Identity=47.3389355742297, Blast_Score=302, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=54.2234332425068, Blast_Score=409, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 39408; Mature: 39277

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSFGKIFRVSTFGESHGGGVGVILDGCPPKLKIDIKLIQNELDRRRPGQSDITTPRNE
CCCCCCCEEEEEECCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCC
DDKIEILSGIKEGLTLGTPIAMLVRNKDQRPGDYNNLEQVFRPSHADGTYHLKYGIQAGS
CCHHHHHHHHHHCCCCCCCHHHEECCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEEEECC
GGGRASARETIGRVAAGAVAKQLLKNLCNTEILSWVKRIHDIDSDVNKEKISLNKIDSNI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEHHHHCCCC
VRCPDEKVSAEMIDRIKDLKRQGDSCGGVIECLVRNVPSGLGMPVFDKLEADLAKALMSL
EECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
PATKGFEIGSGFSGTYLKGSEHNDSFIKSDDISKLRTTSNNSGGIQGGISNGENIEMKIA
CCCCCCCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
FKPTATIGKEQKTVNAEGKEVLMKAKGRHDPCVLPRAVPMVDAMVALVLADHLLLNNAQC
ECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
GLMKN
CCCCC
>Mature Secondary Structure 
SSSFGKIFRVSTFGESHGGGVGVILDGCPPKLKIDIKLIQNELDRRRPGQSDITTPRNE
CCCCCCEEEEEECCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCC
DDKIEILSGIKEGLTLGTPIAMLVRNKDQRPGDYNNLEQVFRPSHADGTYHLKYGIQAGS
CCHHHHHHHHHHCCCCCCCHHHEECCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEEEECC
GGGRASARETIGRVAAGAVAKQLLKNLCNTEILSWVKRIHDIDSDVNKEKISLNKIDSNI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEHHHHCCCC
VRCPDEKVSAEMIDRIKDLKRQGDSCGGVIECLVRNVPSGLGMPVFDKLEADLAKALMSL
EECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
PATKGFEIGSGFSGTYLKGSEHNDSFIKSDDISKLRTTSNNSGGIQGGISNGENIEMKIA
CCCCCCCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
FKPTATIGKEQKTVNAEGKEVLMKAKGRHDPCVLPRAVPMVDAMVALVLADHLLLNNAQC
ECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
GLMKN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA