Click here to switch to the map view.

The map label for this gene is obgE

Identifier: 78778606

GI number: 78778606

Start: 213614

End: 214597

Strand: Direct

Name: obgE

Synonym: PMT9312_0220

Alternate gene names: 78778606

Gene position: 213614-214597 (Clockwise)

Preceding gene: 78778605

Following gene: 78778607

Centisome position: 12.5

GC content: 34.76

Gene sequence:

>984_bases
GTGCAATTTATTGATCAAGCAAACATTATTCTTAAAGCTGGAAAAGGTGGGAATGGAATAGTTTCATTTAGAAGAGAAAA
ATTCGTTCCTGCTGGAGGACCATCGGGGGGGAATGGTGGCAGAGGGGGGTCAATAATATTGGTGGCTGATAATAATCTTC
AAACATTATTAGATTTTAAATTCAAAAGAGAAATAATTGCTGAAGATGGATGCAAAGGAGGTCCTAATAAAAGATCTGGT
GCTTCAGGTGAGGATACAATCCTTAAAGTTCCTTGCGGTACAGAAATAAGGGATTTTAAAACCGGCATTATTTTAGGAGA
CTTAACTAAAAATAAAGAGAGTTTAACTATTGCCATTGGGGGAAGAGGTGGACATGGTAATGCTTACTATTTAAGTAATC
AAAATAGAGCCCCAGAATCATTTACTGAAGGACAAGATGGTGAGATATGGGAGGTTCAATTAGAACTTAAACTCCTTGCA
GAGGTCGGGATTATAGGCCTACCAAATGCAGGGAAAAGTACTTTAATATCCGTCCTGTCATCTGCTCGTCCAAAAATAGC
AAACTATCCTTTCACAACTTTAATACCTAACTTAGGTGTAGTTAGAAAAGTAGATGGAAATGGTTGTCTTTTTGCCGATA
TACCTGGATTAATATCAGGGGCAGCAGATGGAGTAGGTTTAGGTCATGATTTTTTGAGGCACATTCAAAGAACGAAGATA
CTTGTGCACTTAATTGATTCAATTGCAGAAAATCCTATTCATGATTTTGAGATAATTGAGCAGGAATTAAGAAAATATGG
AAAAGGTCTTATAGACAAAGAGAGGATAATAGTATTAAATAAAATGGAACTTGTAGATGATGATTATTTGCAAATAATCA
CAAAAAAGTTAGAAGAATTATCTAAAAAAAAAGTTTTAGCAATTTCTTCATCTTTAAAAAAAGGTTTATCTTCACTGCTT
TTTGAGGTATGGAAAAGGATCTAA

Upstream 100 bases:

>100_bases
GATTGAAGATGCTGCACTCAACGAGGGTGGACCTGGTTGCAGTATTGCGTGGATAAAATAAAATTTAAAATATTTAAAAA
CCATTGTTTAACTACATTAA

Downstream 100 bases:

>100_bases
ATTAAATTAAATTTTTTTTGTAAATAAATATACTTGATTTAATAATGAAAATTAGCCATAAATAAGATACTTCTTTAACC
TAAACATGAATTTCTACAGT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MQFIDQANIILKAGKGGNGIVSFRREKFVPAGGPSGGNGGRGGSIILVADNNLQTLLDFKFKREIIAEDGCKGGPNKRSG
ASGEDTILKVPCGTEIRDFKTGIILGDLTKNKESLTIAIGGRGGHGNAYYLSNQNRAPESFTEGQDGEIWEVQLELKLLA
EVGIIGLPNAGKSTLISVLSSARPKIANYPFTTLIPNLGVVRKVDGNGCLFADIPGLISGAADGVGLGHDFLRHIQRTKI
LVHLIDSIAENPIHDFEIIEQELRKYGKGLIDKERIIVLNKMELVDDDYLQIITKKLEELSKKKVLAISSSLKKGLSSLL
FEVWKRI

Sequences:

>Translated_327_residues
MQFIDQANIILKAGKGGNGIVSFRREKFVPAGGPSGGNGGRGGSIILVADNNLQTLLDFKFKREIIAEDGCKGGPNKRSG
ASGEDTILKVPCGTEIRDFKTGIILGDLTKNKESLTIAIGGRGGHGNAYYLSNQNRAPESFTEGQDGEIWEVQLELKLLA
EVGIIGLPNAGKSTLISVLSSARPKIANYPFTTLIPNLGVVRKVDGNGCLFADIPGLISGAADGVGLGHDFLRHIQRTKI
LVHLIDSIAENPIHDFEIIEQELRKYGKGLIDKERIIVLNKMELVDDDYLQIITKKLEELSKKKVLAISSSLKKGLSSLL
FEVWKRI
>Mature_327_residues
MQFIDQANIILKAGKGGNGIVSFRREKFVPAGGPSGGNGGRGGSIILVADNNLQTLLDFKFKREIIAEDGCKGGPNKRSG
ASGEDTILKVPCGTEIRDFKTGIILGDLTKNKESLTIAIGGRGGHGNAYYLSNQNRAPESFTEGQDGEIWEVQLELKLLA
EVGIIGLPNAGKSTLISVLSSARPKIANYPFTTLIPNLGVVRKVDGNGCLFADIPGLISGAADGVGLGHDFLRHIQRTKI
LVHLIDSIAENPIHDFEIIEQELRKYGKGLIDKERIIVLNKMELVDDDYLQIITKKLEELSKKKVLAISSSLKKGLSSLL
FEVWKRI

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=321, Percent_Identity=36.4485981308411, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI111955139, Length=286, Percent_Identity=34.6153846153846, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI111955063, Length=140, Percent_Identity=40, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI58761500, Length=152, Percent_Identity=34.2105263157895, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1789574, Length=328, Percent_Identity=45.7317073170732, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1787454, Length=129, Percent_Identity=37.984496124031, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17508313, Length=283, Percent_Identity=38.1625441696113, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17552324, Length=308, Percent_Identity=29.5454545454545, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17509631, Length=172, Percent_Identity=31.9767441860465, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6321962, Length=159, Percent_Identity=39.622641509434, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6319281, Length=125, Percent_Identity=36.8, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20129375, Length=322, Percent_Identity=36.3354037267081, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24585318, Length=293, Percent_Identity=35.1535836177474, Blast_Score=137, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24640873, Length=151, Percent_Identity=34.4370860927152, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24640877, Length=151, Percent_Identity=34.4370860927152, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24640875, Length=151, Percent_Identity=34.4370860927152, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21356473, Length=108, Percent_Identity=36.1111111111111, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 35412; Mature: 35412

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFIDQANIILKAGKGGNGIVSFRREKFVPAGGPSGGNGGRGGSIILVADNNLQTLLDFK
CCCCCCCCEEEEECCCCCCEEEEHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
FKREIIAEDGCKGGPNKRSGASGEDTILKVPCGTEIRDFKTGIILGDLTKNKESLTIAIG
HHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHCCCEEEEECCCCCCEEEEEEE
GRGGHGNAYYLSNQNRAPESFTEGQDGEIWEVQLELKLLAEVGIIGLPNAGKSTLISVLS
CCCCCCCEEEECCCCCCCCHHCCCCCCCEEEEEEEEEEHHHCCEEECCCCCHHHHHHHHH
SARPKIANYPFTTLIPNLGVVRKVDGNGCLFADIPGLISGAADGVGLGHDFLRHIQRTKI
HCCCCCCCCCHHHHCCCCCEEEEECCCCEEEEECCHHHHCCCCCCCCCHHHHHHHHHHHH
LVHLIDSIAENPIHDFEIIEQELRKYGKGLIDKERIIVLNKMELVDDDYLQIITKKLEEL
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHCCHHHHHHHHHHHHHH
SKKKVLAISSSLKKGLSSLLFEVWKRI
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQFIDQANIILKAGKGGNGIVSFRREKFVPAGGPSGGNGGRGGSIILVADNNLQTLLDFK
CCCCCCCCEEEEECCCCCCEEEEHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
FKREIIAEDGCKGGPNKRSGASGEDTILKVPCGTEIRDFKTGIILGDLTKNKESLTIAIG
HHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHCCCEEEEECCCCCCEEEEEEE
GRGGHGNAYYLSNQNRAPESFTEGQDGEIWEVQLELKLLAEVGIIGLPNAGKSTLISVLS
CCCCCCCEEEECCCCCCCCHHCCCCCCCEEEEEEEEEEHHHCCEEECCCCCHHHHHHHHH
SARPKIANYPFTTLIPNLGVVRKVDGNGCLFADIPGLISGAADGVGLGHDFLRHIQRTKI
HCCCCCCCCCHHHHCCCCCEEEEECCCCEEEEECCHHHHCCCCCCCCCHHHHHHHHHHHH
LVHLIDSIAENPIHDFEIIEQELRKYGKGLIDKERIIVLNKMELVDDDYLQIITKKLEEL
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHCCHHHHHHHHHHHHHH
SKKKVLAISSSLKKGLSSLLFEVWKRI
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA