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The map label for this gene is cysC [H]

Identifier: 78778554

GI number: 78778554

Start: 161684

End: 162319

Strand: Direct

Name: cysC [H]

Synonym: PMT9312_0168

Alternate gene names: 78778554

Gene position: 161684-162319 (Clockwise)

Preceding gene: 78778553

Following gene: 78778556

Centisome position: 9.46

GC content: 31.6

Gene sequence:

>636_bases
ATGATGCAAAAAATGAAAGAACAAGATCAAACAAATTCAACCAATATAAAGTGGCACAATTTAACTATTGATAGAGATAA
GTTAGAGAAAATGAGAGGTCATAAAGGAATGGTCATTTGGTTTACAGGTTTATCAGGCTCTGGTAAAAGTACTTTGGCCA
ACGCTTTAAATGAAGTTTTACACTTAGATGGTTTTTCAACTTACGTGTTGGATGGAGATAATATAAGGCACGGTTTATGT
AGAGATCTTGGTTTTTCGGATGAAGATAGAGAAGAAAATATAAGAAGAATTGGAGAAGTTGCGAATTTATTTATGAATGC
TGGGATAATAACTATTACAGCATTCGTTTCACCATTTATTAGCGATAGAGATAAGGTGAGAAAAATTATTGGATCTAAAG
ATTTTATTGAAGTTTATTGTGCTGCAGATATCAAAGTTTGCGAAAACAGGGATACTAAAGGTCTTTATAAGAAAGCTCGT
TTAGGGGAAATTAAGGATTTTACTGGGATTTCTAGTCCATATGAAGCTCCTCATAATCCAGAAATTATTGTTGATACAGG
TTCGTTAGATTTAAAGGATTCTGTTGAAAAAGTTATTAACTATCTTAAAAAAGAAAACTTCCTTAAAAAGGGTTAA

Upstream 100 bases:

>100_bases
CCAGTTACAGGGCGATATGGTATTGAAATCAATTGAGTTTCTTCGTAAAGAGGGATTTCATAATTTATGAAGCAAGGGTT
AAGATAGGTTTTTAATTTTG

Downstream 100 bases:

>100_bases
TAGAGAAATATAAGTTCATTTATTTTGAAGATAATTGTCCGCTCCAATATTTGATAACTTACTATTTTTAGTTCTTACCT
GTGTATGAAGATTTTCTCTG

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MMQKMKEQDQTNSTNIKWHNLTIDRDKLEKMRGHKGMVIWFTGLSGSGKSTLANALNEVLHLDGFSTYVLDGDNIRHGLC
RDLGFSDEDREENIRRIGEVANLFMNAGIITITAFVSPFISDRDKVRKIIGSKDFIEVYCAADIKVCENRDTKGLYKKAR
LGEIKDFTGISSPYEAPHNPEIIVDTGSLDLKDSVEKVINYLKKENFLKKG

Sequences:

>Translated_211_residues
MMQKMKEQDQTNSTNIKWHNLTIDRDKLEKMRGHKGMVIWFTGLSGSGKSTLANALNEVLHLDGFSTYVLDGDNIRHGLC
RDLGFSDEDREENIRRIGEVANLFMNAGIITITAFVSPFISDRDKVRKIIGSKDFIEVYCAADIKVCENRDTKGLYKKAR
LGEIKDFTGISSPYEAPHNPEIIVDTGSLDLKDSVEKVINYLKKENFLKKG
>Mature_211_residues
MMQKMKEQDQTNSTNIKWHNLTIDRDKLEKMRGHKGMVIWFTGLSGSGKSTLANALNEVLHLDGFSTYVLDGDNIRHGLC
RDLGFSDEDREENIRRIGEVANLFMNAGIITITAFVSPFISDRDKVRKIIGSKDFIEVYCAADIKVCENRDTKGLYKKAR
LGEIKDFTGISSPYEAPHNPEIIVDTGSLDLKDSVEKVINYLKKENFLKKG

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=202, Percent_Identity=48.5148514851485, Blast_Score=201, Evalue=3e-52,
Organism=Homo sapiens, GI34447231, Length=213, Percent_Identity=46.9483568075117, Blast_Score=200, Evalue=6e-52,
Organism=Homo sapiens, GI62912492, Length=213, Percent_Identity=46.9483568075117, Blast_Score=200, Evalue=6e-52,
Organism=Escherichia coli, GI1789107, Length=195, Percent_Identity=52.3076923076923, Blast_Score=223, Evalue=7e-60,
Organism=Caenorhabditis elegans, GI17542422, Length=205, Percent_Identity=50.2439024390244, Blast_Score=205, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6322852, Length=202, Percent_Identity=50.4950495049505, Blast_Score=192, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24667032, Length=213, Percent_Identity=46.9483568075117, Blast_Score=188, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24667028, Length=213, Percent_Identity=46.9483568075117, Blast_Score=188, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24667036, Length=213, Percent_Identity=46.9483568075117, Blast_Score=188, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24667040, Length=208, Percent_Identity=47.1153846153846, Blast_Score=188, Evalue=2e-48,
Organism=Drosophila melanogaster, GI116007838, Length=208, Percent_Identity=47.1153846153846, Blast_Score=187, Evalue=6e-48,
Organism=Drosophila melanogaster, GI24667044, Length=208, Percent_Identity=47.1153846153846, Blast_Score=187, Evalue=6e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 23877; Mature: 23877

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQKMKEQDQTNSTNIKWHNLTIDRDKLEKMRGHKGMVIWFTGLSGSGKSTLANALNEVL
CCCHHHHHHCCCCCCEEEEEEEECHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHH
HLDGFSTYVLDGDNIRHGLCRDLGFSDEDREENIRRIGEVANLFMNAGIITITAFVSPFI
HCCCCEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
SDRDKVRKIIGSKDFIEVYCAADIKVCENRDTKGLYKKARLGEIKDFTGISSPYEAPHNP
CCHHHHHHHHCCCCCEEEEEECCEEEECCCCCHHHHHHHHCCCCHHHCCCCCCCCCCCCC
EIIVDTGSLDLKDSVEKVINYLKKENFLKKG
EEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMQKMKEQDQTNSTNIKWHNLTIDRDKLEKMRGHKGMVIWFTGLSGSGKSTLANALNEVL
CCCHHHHHHCCCCCCEEEEEEEECHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHH
HLDGFSTYVLDGDNIRHGLCRDLGFSDEDREENIRRIGEVANLFMNAGIITITAFVSPFI
HCCCCEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
SDRDKVRKIIGSKDFIEVYCAADIKVCENRDTKGLYKKARLGEIKDFTGISSPYEAPHNP
CCHHHHHHHHCCCCCEEEEEECCEEEECCCCCHHHHHHHHCCCCHHHCCCCCCCCCCCCC
EIIVDTGSLDLKDSVEKVINYLKKENFLKKG
EEEEECCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]