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The map label for this gene is holB [H]

Identifier: 78778517

GI number: 78778517

Start: 126658

End: 127617

Strand: Reverse

Name: holB [H]

Synonym: PMT9312_0131

Alternate gene names: 78778517

Gene position: 127617-126658 (Counterclockwise)

Preceding gene: 78778518

Following gene: 78778515

Centisome position: 7.47

GC content: 26.04

Gene sequence:

>960_bases
ATGATTGAGGTAAAAAAAAAATTATTCTTTAATGAAGAAGTTAATACATATCTTAAAAGCATAATTAGAAATAAATCATT
TGCTAATGGTTACATATTTAATGGTGCTGAAGGAGTAGGGAAACAACAAACTGCTCTTCAATTTATAAAAGAGATTTTCA
AGCAATCTTCTCCAGTCGGAAATATTGAAGAAAGAATTACAAACAATAACCATCCGGATTTTCTCATTATCGAACCTAAT
TCGATTTTGGAATCTAAAAGGTCAAAAAGTTCCGATCTTGAAAAAACAACAAAAAGTGGATCTGAGATTATTAAGATTGC
TCAAATACGTAATATCAAAACTTTTCTTGGTCAAAAATCAATAAACTCAGACAAAAAAATTGTTTTAATTATTGATGCCC
ACCTTCTAAACGAAGCAGCCTCAAATTGCCTTTTAAAAATACTAGAAGAACCCAACAATGGCATTTTTATTTTATTAACA
TCAAAATTAAATCTTCTCTTAGATACGATCATATCAAGATGTCAATTAGTCAGGTTTCGATCCTTTTCTAGTAAACAAAT
AAACTCTCTTTTCAAAGATTATTTAGATCCTTCTCAATTTAACATTAATACAAAATTGAAATTCGAAGATGTAATAAACT
CTGCAAATGGATCTCCAGGGCAATTATTGAAAAATATTGAAATTTGGAATGAATTACCAAGTGAAATTACAAATAAATTA
ATTTTTCCAATAAAAAATAGTCTAGAAATTTTAGAAGTATCTAAATTAATATATGAAAAATTAGAAATTTATCAACAGAT
TTGCTTAGTCAATTTTATTCAAATTATTTGGTGGAGAAATACAAAAAATATTGATCTAGTAAAAAAGCTTGAAAATTTAA
AATTTTATTTAAGAACAAATATTCAACCAAGGTTGGCATGGGAAATAACCTTTTTAAAAATTTCAATGGAAGATATATGA

Upstream 100 bases:

>100_bases
CCAGAGAAAAAAAATGGAAAGTAATATCTGCCTCACAAAATATTAAAACTATTTCTAATCAAATTAAAGAGACTCTATTA
AACAATTTTTCTAATGACAA

Downstream 100 bases:

>100_bases
AATTTAATCTATTACAGAATTCATTAGATTAGGATTTCGTGCTTGAATAAAATCTTGCTTGGCAGCTTCAACTTGAGAGC
CAATAGGTAACTCAAGACAA

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MIEVKKKLFFNEEVNTYLKSIIRNKSFANGYIFNGAEGVGKQQTALQFIKEIFKQSSPVGNIEERITNNNHPDFLIIEPN
SILESKRSKSSDLEKTTKSGSEIIKIAQIRNIKTFLGQKSINSDKKIVLIIDAHLLNEAASNCLLKILEEPNNGIFILLT
SKLNLLLDTIISRCQLVRFRSFSSKQINSLFKDYLDPSQFNINTKLKFEDVINSANGSPGQLLKNIEIWNELPSEITNKL
IFPIKNSLEILEVSKLIYEKLEIYQQICLVNFIQIIWWRNTKNIDLVKKLENLKFYLRTNIQPRLAWEITFLKISMEDI

Sequences:

>Translated_319_residues
MIEVKKKLFFNEEVNTYLKSIIRNKSFANGYIFNGAEGVGKQQTALQFIKEIFKQSSPVGNIEERITNNNHPDFLIIEPN
SILESKRSKSSDLEKTTKSGSEIIKIAQIRNIKTFLGQKSINSDKKIVLIIDAHLLNEAASNCLLKILEEPNNGIFILLT
SKLNLLLDTIISRCQLVRFRSFSSKQINSLFKDYLDPSQFNINTKLKFEDVINSANGSPGQLLKNIEIWNELPSEITNKL
IFPIKNSLEILEVSKLIYEKLEIYQQICLVNFIQIIWWRNTKNIDLVKKLENLKFYLRTNIQPRLAWEITFLKISMEDI
>Mature_319_residues
MIEVKKKLFFNEEVNTYLKSIIRNKSFANGYIFNGAEGVGKQQTALQFIKEIFKQSSPVGNIEERITNNNHPDFLIIEPN
SILESKRSKSSDLEKTTKSGSEIIKIAQIRNIKTFLGQKSINSDKKIVLIIDAHLLNEAASNCLLKILEEPNNGIFILLT
SKLNLLLDTIISRCQLVRFRSFSSKQINSLFKDYLDPSQFNINTKLKFEDVINSANGSPGQLLKNIEIWNELPSEITNKL
IFPIKNSLEILEVSKLIYEKLEIYQQICLVNFIQIIWWRNTKNIDLVKKLENLKFYLRTNIQPRLAWEITFLKISMEDI

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004622 [H]

Pfam domain/function: NA

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 36872; Mature: 36872

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEVKKKLFFNEEVNTYLKSIIRNKSFANGYIFNGAEGVGKQQTALQFIKEIFKQSSPVG
CCCCHHHHHHCHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCC
NIEERITNNNHPDFLIIEPNSILESKRSKSSDLEKTTKSGSEIIKIAQIRNIKTFLGQKS
CHHHHHCCCCCCCEEEECCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
INSDKKIVLIIDAHLLNEAASNCLLKILEEPNNGIFILLTSKLNLLLDTIISRCQLVRFR
CCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
SFSSKQINSLFKDYLDPSQFNINTKLKFEDVINSANGSPGQLLKNIEIWNELPSEITNKL
CCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHE
IFPIKNSLEILEVSKLIYEKLEIYQQICLVNFIQIIWWRNTKNIDLVKKLENLKFYLRTN
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEECC
IQPRLAWEITFLKISMEDI
CCCEEEEEEEEEEEEECCC
>Mature Secondary Structure
MIEVKKKLFFNEEVNTYLKSIIRNKSFANGYIFNGAEGVGKQQTALQFIKEIFKQSSPVG
CCCCHHHHHHCHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCC
NIEERITNNNHPDFLIIEPNSILESKRSKSSDLEKTTKSGSEIIKIAQIRNIKTFLGQKS
CHHHHHCCCCCCCEEEECCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
INSDKKIVLIIDAHLLNEAASNCLLKILEEPNNGIFILLTSKLNLLLDTIISRCQLVRFR
CCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
SFSSKQINSLFKDYLDPSQFNINTKLKFEDVINSANGSPGQLLKNIEIWNELPSEITNKL
CCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHE
IFPIKNSLEILEVSKLIYEKLEIYQQICLVNFIQIIWWRNTKNIDLVKKLENLKFYLRTN
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEECC
IQPRLAWEITFLKISMEDI
CCCEEEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]