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The map label for this gene is aroK

Identifier: 78778496

GI number: 78778496

Start: 112384

End: 112941

Strand: Direct

Name: aroK

Synonym: PMT9312_0111

Alternate gene names: 78778496

Gene position: 112384-112941 (Clockwise)

Preceding gene: 78778491

Following gene: 78778498

Centisome position: 6.58

GC content: 29.39

Gene sequence:

>558_bases
ATGGAACAATCCATTATCGAAAAAACAGTTAAGGTTATCAAGGGTAGAAGCATATTTTTAATCGGTATGATGGGTTGTGG
TAAGTCACAAACTGGTTTGAAACTGGCTGAATTATTGAAGTATAAATACATTGATTTAGATTCATTAATAGAGAAGTTGG
CCAAAAAATCTATCAATCAAATTTTTAACGATGAAGGAGAAGATAATTTTCGTGAATTAGAAACAAGCTGCCTTAAAGAA
ACTATCAAAATTCCTTCATTAGTAATATCAACTGGTGGAGGGATAGTTACTAAATCCGAAAACTGGGGAATATTAAGACA
GGGAATAATTGCTTGGATAGATCTCGACAAAGATATCGCAATTGAGAGATTGAAAAATGAAATTGAAAACAGGCCATTAC
TTCAGGGAAAGAATCTAAATGATTTATATATGAGTATTTTAAAATCCAGAGAAAATTTATATTCTCAAGCCGATTTAAGA
ATTCAAGTAAAAAATGAAAATATTGAAGAAGTTGCTATAAAAATAATCAATGCGATGCATAAAGAAATAAATAATTAA

Upstream 100 bases:

>100_bases
ACGCATTCACGTCCTTTTCCATGTAATGGTTTGGATTGTGTAGAAGTCATACCTGTCTGCGATAATACTATCTTAAGGTT
TTAAATACGCTTTTGTCTTT

Downstream 100 bases:

>100_bases
TCTGGTTCAATTCTCACCGCAAACCATTTAATAACGTATCCTAACTTTATTTCTAATTCATAAGTGCTTTCCAATAATTC
TTCAAAAAATTCCTGATCAG

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MEQSIIEKTVKVIKGRSIFLIGMMGCGKSQTGLKLAELLKYKYIDLDSLIEKLAKKSINQIFNDEGEDNFRELETSCLKE
TIKIPSLVISTGGGIVTKSENWGILRQGIIAWIDLDKDIAIERLKNEIENRPLLQGKNLNDLYMSILKSRENLYSQADLR
IQVKNENIEEVAIKIINAMHKEINN

Sequences:

>Translated_185_residues
MEQSIIEKTVKVIKGRSIFLIGMMGCGKSQTGLKLAELLKYKYIDLDSLIEKLAKKSINQIFNDEGEDNFRELETSCLKE
TIKIPSLVISTGGGIVTKSENWGILRQGIIAWIDLDKDIAIERLKNEIENRPLLQGKNLNDLYMSILKSRENLYSQADLR
IQVKNENIEEVAIKIINAMHKEINN
>Mature_185_residues
MEQSIIEKTVKVIKGRSIFLIGMMGCGKSQTGLKLAELLKYKYIDLDSLIEKLAKKSINQIFNDEGEDNFRELETSCLKE
TIKIPSLVISTGGGIVTKSENWGILRQGIIAWIDLDKDIAIERLKNEIENRPLLQGKNLNDLYMSILKSRENLYSQADLR
IQVKNENIEEVAIKIINAMHKEINN

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786587, Length=173, Percent_Identity=32.3699421965318, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI87082255, Length=167, Percent_Identity=30.5389221556886, Blast_Score=79, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 21050; Mature: 21050

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQSIIEKTVKVIKGRSIFLIGMMGCGKSQTGLKLAELLKYKYIDLDSLIEKLAKKSINQ
CCHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IFNDEGEDNFRELETSCLKETIKIPSLVISTGGGIVTKSENWGILRQGIIAWIDLDKDIA
HHCCCCCHHHHHHHHHHHHHHHHCCHHEEECCCCEEECCCCCCHHHHHHHHEEECCHHHH
IERLKNEIENRPLLQGKNLNDLYMSILKSRENLYSQADLRIQVKNENIEEVAIKIINAMH
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
KEINN
HHHCC
>Mature Secondary Structure
MEQSIIEKTVKVIKGRSIFLIGMMGCGKSQTGLKLAELLKYKYIDLDSLIEKLAKKSINQ
CCHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IFNDEGEDNFRELETSCLKETIKIPSLVISTGGGIVTKSENWGILRQGIIAWIDLDKDIA
HHCCCCCHHHHHHHHHHHHHHHHCCHHEEECCCCEEECCCCCCHHHHHHHHEEECCHHHH
IERLKNEIENRPLLQGKNLNDLYMSILKSRENLYSQADLRIQVKNENIEEVAIKIINAMH
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
KEINN
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]